Paradoxical effects of overexpression of the type I insulin-like growth factor (IGF) receptor on the responsiveness of human breast cancer cells to IGFs and estradiol

Endocrinology

Volumn 137, Issue 4, 1996, Pages 1177-1186

  Daws, Michael R ^a   Westley, Bruce R ^a   May, Felicity E B ^a  

^a ROYAL VICTORIA INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTRADIOL RECEPTOR; SOMATOMEDIN C; SOMATOMEDIN RECEPTOR;

ARTICLE; BREAST CANCER; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GROWTH REGULATION; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0029919565     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.4.8625887     Document Type: Article

References (50)

1. Ullrich A, Gray A, Tama W, Yang-Feng T, Tsubokawa M, Collins C, Henzel W, Le Bon T, Kathuria S, Chen E, Jacobs S, Francke U, Ramachandran J, Fujita-Yamaguchi Y 1986 IGF-1 receptor primary structure: comparison with insulin receptor suggests structural determinants that define structural specificity. EMBO J 5:2503-2512
2. Macaulay VM 1992 Insulin-like growth factors and cancer. Br J Cancer 65:311-320
3. Westley B, May FEB 1991 IGFs and control of cell proliferation in breast cancer and other malignancies. Reviews on Endocrine-Related Cancer 39:29-34
4. Osborne CK, Clemmons DR, Arteaga CL 1990 Regulation of breast cancer growth by insulin-like growth factors. J Steroid Biochem Mol Biol 37:805-809
5. Karey KP, Sirbasku DA 1988 Differential responsiveness of human breast cancer cell lines MCF-7 and T 47D to growth factors and 17β-estradiol. Cancer Res 48:4083-4092
6. Huff KK, Kaufman D, Gabbay KH, Spencer EM, Lippman ME, Dickson RB 1986 Secretion of an IGF-I-related protein by human breast cancer cells. Cancer Res 46:4613-4619
7. Foekens JA, Portengen H, Janssen M, Klijn JGM 1989 IGF-I receptors and IGF-I-like activity in human primary breast cancer. Cancer 63:2139-2147
8. Freed KA, Herington AC 1989 IGF-I and its autocrine role in growth of human breast cancer cells in culture. J Mol Endocrinol 3:183-190
9. Huff KK, Knabbe C, Lindsey R, Kaufman D, Bronzert D, Lippman ME, Dickson RB 1988 Multihormonal regulation of insulin-like growth factor-I-related protein in MCF-7 human breast cancer cells. Mol Endocrinol 2:200-208
10. Yee D, Paik S, Lebovic GS, Marcus RR, Favoni RE, Cullen KJ, Lippman ME, Rosen N 1989 Analysis of IGF-I gene expression in malignancy: evidence for a paracrine role in human breast cancer. Mol Endocrinol 3:509-517
11. Doglio A, Dani C, Fredrikson G, Grimaldi P, Ailhaud G 1987 Acute regulation of insulin-like growth factor-I gene expression by growth hormone during adipose cell differentiation. EMBO J 6:4011-4016
12. Colletti RB, Roberts JD, Devlin JT, Copeland KC 1989 Effect of tamoxifen on plasma insulin-like growth factor I in patients with breast cancer. Cancer Res 49:1882-1884
13. Pollak M, Costantino J, Polychronakos C, Blauer S, Guyda H, Redmond C, Fisher B, Maigolese R 1990 Effect of tamoxifen on serum insulin-like growth factor I levels in stage I breast cancer patients. J Natl Cancer Inst 82:1693-1697
14. Huynh HT, Tetenes E, Wallace L, Pollak M 1993 In vivo inhibition of insulin-like growth factor I gene expression by tamoxifen. Cancer Res 53:1727-1731
15. Osborne CK, Corpnado EB, Kitten LJ, Arteaga CL, Fuqua SAW, Ramasharma K, Marshall M, Li CH 1989 IGF-II: a potential autocrine/paracrine growth factor for human breast cancer acting via the IGF-I receptor. Mol Endocrinol 3:1701-1709
16. Lee AV, Darbre P, King RJB 1994 Processing of insulin-like growth factor II (IGF-II) by human breast cancer cells. Mol Cell Endocrinol 99:211-220
17. Yee D, Cullen KJ, Paik S, Perdue JF, Hampton B, Schwartz A, Lippman ME, Rosen N 1988 IGF-II mRNA expression in human breast cancer. Cancer Res 48:6691-6696
18. Stewart AJ, Johnson MD, May FEB, Westley BR 1990 Role of IGFs and the type I IGF receptor in the estrogen stimulated proliferation of human breast cancer cells. J Biol Chem 265:21172-21178
19. Van Der Burg B, Rutteman GR, Blankenstein MA, De Laat SW, Van Zoelen EJJ 1988 Mitogenic stimulation of human breast cancer cells in a growth factor-defined medium: synergistic action of insulin and estrogen. J Cell Physiol 134:101-108
20. Thorsen T, Lahooti H, Rasmussen M, Aakvaag A 1992 Estradiol treatment increases the sensitivity of MCF-7 cells for the growth stimulatory effects of IGF-I. J Steroid Biochem Mol Biol 41:537-540
21. Wiseman LR, Johnson MD, Wakeling AE, Lykkesfeldt AE, May FEB, Westley BR 1993 Type I IGF receptor and acquired tamoxifen resistance in estrogen-responsive human breast cancer cells. Eur J Cancer 29:2256-2264
22. Kaleko M, Rutter WJ, Miller AD 1990 Overexpression of the human IGF-I receptor promotes ligand-dependant neoplastic transformation. Mol Cell Biol 10:464-473
23. Johnson MD, Westley BR, May FEB 1989 Estrogenic activity of tamoxifen and its metabolites on gene regulation and cell proliferation in MCF-7 breast cancer cells. Br J Cancer 59:727-738
24. Downs TR, Wilfinger WW 1983 Fluorimetric quantification of DNA in cells and tissue. Anal Biochem 132:538-554
25. Van Zoelen EJJ 1989 Receptor-ligand interaction: a new method for determining binding parameters without a priori assumptions on non-specific binding. Biochem J 262:549-556
26. White MF 1990 The insulin receptor tyrosine kinase. In: Siddle K, Hutton JC (eds) Peptide Hormone Action. IRL Press, Oxford, pp 223-250
27. Fraker PJ, Speck JC 1978 Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril. Biochem Biophys Res Commun 80:849-857
28. Steele-Perkins G, Turner J, Edman JC, Hari J, Pierce SB, Stover C, Rutter WJ, Roth RA 1988 Expression and characterization of a functional human IGF-I receptor. J Biol Chem 263:11486-11492
29. Quinn LS, Steinmetz B, Maas A, Ong L, Kaleko M 1994 Type-1 insulin-like growth factor receptor overexpression produces dual effects on myoblast proliferation and differentiation. J Cell Physiol 159:387-398
30. Poulsom R, Wright NA 1993 Trefoil peptides: a newly recognized family of epithelial mucin-associated molecules. Am J Physiol 265: 205-213
31. Westley B, May FEB 1984 The human genome contains multiple sequences of varying homology to mouse mammary tumour virus DNA. Gene 28:221-227
32. Piggott NH, Henry JA, May FEB, Westley BR 1991 Antipeptide antibodies against the pNR-2 estrogen-regulated protein of human breast cancer cells and detection of pNR-2 expression in normal tissues by immunohistochemistry. J Pathol 163:95-104
33. Scatchard G 1949 The attraction of proteins for small molecules and ions. Ann NY Acad Sci 51:660-672
34. May FEB, Westley BR 1988 Identification and characterization of estrogen-regulated RNAs in human breast cancer cells. J Biol Chem 263:12901-12908
35. Stewart AJ, Westley BR, May FEB 1992 Modulation of the proliferative response of breast cancer cells to growth factors by oestrogen. Br J Cancer 66:640-648
36. Bacus SS, Huberman E, Chin D, Kiguchi K, Simpson S, Lippman M, Lupu R 1992 A ligand for the erbB-2 oncogene product (gp31) induces differentiation of human breast cancer cells. Cell Growth Differ 3:401-411
37. Staebler A, Sommers C, Mueller SC, Byers S, Thompson EW, Lupu R 1994 Modulation of breast cancer progression and differentiation by the gp31/heregulin. Breast Cancer Res Treat 32:175-182
38. Traverse S, Seedorf K, Paterson H, Marshall CJ, Cohen P, Ullrich A 1994 EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor. Current Biology 4:694-701
39. Kato H, Faria TN, Stannard B, Levy-Toledano R, Taylor SI, Roberts CT, LeRoith D 1993 Paradoxical biological effects of overexpressed insulin-like growth factor-1 receptors in Chinese hamster ovary cells. J Cell Physiol 156:145-152
40. Myers MG, White MF 1993 The new elements of insulin signalling. Insulin receptor substrate-1 and proteins with SH2 domains. Diabetes 42:643-650
41. Sun XJ, Miralpeix M, Myers MG, Glasheen EM, Backer JM, Kahn CR, White MF 1992 Expression and function of IRS-1 in insulin signal transmission. J Biol Chem 267:22662-22672
42. Peyrat JP, Bonneterre J, Vennin PH, Jammes H, Beuscart R, Hecquet B, Djiane J, Lefebvre J, Demaille A 1990 IGF-1 receptors and IGF-1 in human breast tumours. J Steroid Biochem Mol Biol 37:823-827
43. Bonneterre J, Peyrat JP, Beuscart R, Demaille A 1990 Prognostic significance of IGF-1 receptors in human breast cancer. Cancer Res 50:6932-6935
44. Westley B, May FEB 1993 Mechanism of antiestrogen resistance in cancer cells. Cancer Topics 9:39-41
45. Reddel RR, Alexander IE, Koga M, Shine J, Sutherland RL 1988 Genetic instability and the development of steroid hormone insensitivity in cultured T 47D human breast cancer cells. Cancer Res 48:4340-4347
46. Sukumar S, Carney WP, Barbacid M 1988 Independent molecular pathways in initiation and loss of hormone responsiveness of breast carcinomas. Science 240:524-526
47. Kasid A, Lippman ME, Papageorge AG, Lowy DR, Gelman EP 1985 Transfection of v-rasH DNA into MCF-7 human breast cancer cells bypasses dependence on estrogen for tumorigenicity. Science 228:725-728
48. Daly RJ, Harris WH, Wang DY, Darbre PD 1991 Autocrine production of insulin-like growth factor II using an inducible expression system results in reduced estrogen sensitivity of MCF-7 human breast cancer cells. Cell Growth Differ 2:457-464
49. Cullen KJ, Lippman ME, Chow D, Hill S, Rosen N, Zwiebel JA 1992 Insulin-like growth factor II overexpression in MCF-7 cells induces phenotypic changes associated with malignant progression. Mol Endocrinol 6:91-100
50. Darbre PD, Daly RJ 1990 Transition of human breast cancer cells from an estrogen responsive to unresponsive-state. J Steroid Biochem Mol Biol 37:753-763