Heterogeneity of allergic airway responses in sheep: Differences in signal transduction?

American Journal of Respiratory and Critical Care Medicine

Volumn 154, Issue 4 I, 1996, Pages 843-849

  Ahmed, Tahir ^a,b   D'Brot, Juan ^a   Abraham, William M ^a   Lucio, James ^a   Mendelssohn, Richard ^a   Robinson, Morton J ^a   Shakir, Shahida ^a   Sanpedro, Berta ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b MOUNT SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEPARIN; HISTAMINE; IMMUNOGLOBULIN E; INOSITOL TRISPHOSPHATE;

ALLERGY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; FEMALE; HISTAMINE RELEASE; LUNG LAVAGE; LUNG RESISTANCE; MAST CELL; NONHUMAN; PRIORITY JOURNAL; SHEEP; SIGNAL TRANSDUCTION;

EID: 0029919380     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.154.4.8887573     Document Type: Article

References (48)

1. Casale, T. B., D. Wood, H. B. Richarson, B. Zehr, D. Zavala, and G. W. Hunninghake. 1987. Direct evidence of a role for mast cells in the pathogenesis of antigen-induced bronchoconstriction. J. Clin. Invest. 80:1507-1511.
2. Martin, T. R., S. J. Galli, I. M. Katona, and J. M. Drazen. 1989. Role of mast cells in anaphylaxis. Evidence for the importance of mast cells in the cardiopulmonary alterations and death induced by anti-IgE in mice. J. Clin. Invest. 83:1375-1383.
3. Lai, C. K. W., and S. T. Holgate. 1988. The mast cells in asthma. In A. B. Kay, editor. Clinical Immunology and Allergy: The Allergic Basis of Asthma. Balliere Tindall, London. 37-65.
4. Penner, R. 1988. Multiple signaling pathways control stimulus-secretion coupling in rat peritoneal mast cells. Proc. Natl. Acad. Sci. U.S.A. 85:9856-9860.
5. Penner, R., G. Matthews, and E. Neher. 1988. Regulation of calcium influx by second messengers in rat mast cells. Nature 334:499-504.
6. Metzger, H., G. Alcaraz, R. Hohman, J. P. Kinet, V. Pribluda, and R. Quarto. 1986. The receptor with high affinity for immunoglobulin E. Annu. Rev. Immunol. 4:419-470.
7. Berridge, M. J. 1987. Inositol triphosphate and diacylglycerol: two interacting second messengers. Annu. Rev. Biochem. 56:159-193.
8. Berridge, M. J., and R. F. Irvine. 1984. Inositol trisphosphate, a novel second messenger in cellular signal transduction. Nature 312:315-321.
9. Williamson, J. R., R. H. Cooper, S. K. Joseph, and A. P. Thomas. 1985. Inositol trisphosphate and diacylglycerol as intracellular second messengers in liver. 1985. Am. J. Physiol. 248:C203-216.
10. 32P-inositol 1,4,5-triphosphate in hepatocytes and neutrophils. Nature 319:514-516.
11. Supattapone, S., P. F. Worley, J. M. Barbara, and S. H. Snyder. 1988. Solubilization, purification and characterization of an inositol trisphosphate receptor. J. Biol. Chem. 263:1530-1534.
12. 2+ in the degranulation of skinned mast cells. Agents Actions 20: 157-160.
13. Ghosh, T. K., P. S. Eis, J. M. Mullaney, C. L. Ebert, and D. L. Gill. 1988. Competitive, reversible, and potent antagonism of inositol 1,4,5-trisphosphate-activated calcium release by heparin. J. Biol. Chem. 263:11075-11079.
14. Kobayashi, S., A. V. Somlyo, and A. P. Somlyo. 1988. Heparin inhibits the inositol 1,4,5-trisphosphate-dependent, but not the independent, calcium release induced by guanine nucleotide in vascular smooth muscle. Biochem. Biophys. Res. Commun. 153:625-631.
15. 2+ release from rat liver microsomes. F.E.B.S. Lett. 228:57-59.
16. Ahmed, T., W. M. Abraham, and J. D'Brot. 1992. Effects of inhaled heparin on immunologic and nonimmunologic bronchoconstrictor responses in sheep. Am. Rev. Respir. Dis. 145:566-570.
17. Lucio, J., J. D'Brot, C. B. Guo, W. M. Abraham, L. M. Lichtenstein, A. Kagey-Sobotka, and T. Ahmed. 1992. Immunologic mast cell-mediated responses and histamine release are attenuated by heparin. J. Appl. Physiol. 73:1093-1101.
18. Ahmed, T., T. Syriste, J. Lucio, W. M. Abraham, M. J. Robinson, and J. D'Brot. 1993. Inhibition of antigen-induced airway and cutaneous responses by heparin: a pharmacodynamic study. J. Appl. Physiol. 74:1492-1498.
19. 3-mediated mast cell degranulation? J. Appl. Physiol. 76:893-901.
20. O'Byrne, P. M., J. Dolovich, and F. E. Hargreave. 1987. Late asthmatic responses. Am. Rev. Respir. Dis. 136:740-751.
21. Cartier, A., N. C. Thomson, P. A. Frith, R. Roberts, and F. E. Hargreave. 1982. Allergen-induced increase in bronchial responsiveness to histamine: relationship to the late asthmatic response and change in airway caliber. J. Allergy Clin. Immunol. 70:170-177.
22. Abraham, W. M., W. M. Sielczak, A. Wanner, A. P. Perruchoud, L. Blinder, J. S. Stevenson, A. Ahmed, and L. D. Yerger. 1988. Cellular markers of inflammation in the airways of allergic sheep with and without allergen-induced late responders. Am. Rev. Respir. Dis. 138: 1565-1571.
23. Wanner, A., and M. E. Reinhart. 1978. Respiratory mechanics in conscious sheep: response to methacholine. J. Appl. Physiol. 44:479-482.
24. 2 receptors in airway reactions to histamine in conscious sheep. J. Appl. Physiol. 49:826-833.
25. Erger, R. A., and T. B. Casale. 1992. Comparison of methodologies to measure human lung histamine. J. Immunol. Methods 152:115-121.
26. Zar, J. H. 1974. Biostatistical analysis. Prentice Hall, Englewood Cliffs, NJ.
27. 4 in bronchoalveolar lavage fluid during biphasic allergic bronchoconstriction in sheep. Am. Rev. Respir. Dis. 139: 725-731.
28. Liu, M. C., W. C. Hubbard, D. Proud, B. A. Stealey, S. J. Galli, A. Kagey-Sobotka, E. R. Bleecker, and L. M. Lichtenstein. 1991. Immediate and late inflammatory responses to ragweed antigen challenge of the peripheral airways in allergic asthmatics. Cellular, mediator, and permability changes. Am. Rev. Respir. Dis. 144:51-58.
29. Abraham, W. M. 1988. The role of leukotrienes in allergen-induced late responses in allergic sheep. Ann. N. Y. Acad. Sci. 524:260-270.
30. Wood-Baker, R., J. P. Finnerty, and S. T. Holgate. 1993. Plasma and urinary histamine in allergen-induced early and late phase asthmatic responses. Eur. Respir. J. 6:1138-1144.
31. Schwartz, L. B., and T. R. Bradford. 1986. Regulation of tryptase from human lung mast cells by heparin. Stabilization of the active tetramer. J. Biol. Chem. 261:7372-7379.
32. Sayama, S., R. V. Iozzo, G. S. Lazarus, and N. M. Schecter. 1987. Human skin chymotrypsin-like proteinase chymase. Subcellular localization to mast cell granules and interaction with heparin and other glycosaminoglycans, J. Biol. Chem. 262:6808-6815.
33. Ekre, H. P., B. Fjellner, and O. Hagermark. 1986. Inhibition of complement dependent experimental inflammation in human skin by different heparin fractions. Int. J. Immunopharmacol. 8:277-286.
34. Dolowitz, D. A., and T. F. Dougherty. 1960. The use of heparin as an anti-inflammatory agent. Laryngoscope 70:873-884.
35. Nelson, R. M., O. Cecconi, W. G. Roberts, A. Aruffo, R. J. Linhardt, and M. P. Bevilacqua. 1993. Heparin oligosaccharides bind L- and p-selectin and inhibit acute inflammation. Blood 82:3235-3258.
36. Seeds, E. A., J. Hanns, and C. P. Page. 1993. The effect of heparin and related proteoglycans on allergen and PAF-induced eosinophil infiltration. J. Lipid Medial. 7:269-278.
37. Castellot, J. J., Jr., Cochran, D. L., and M. J. Karnovsky. 1985. Effect of heparin on vascular smooth muscle cell. 1. Cell metabolism. J. Cell. Physiol. 124:21-28.
38. Wright, T. C., Jr., T. V. Johnstone, J. J. Castellot, and M. J. Karnovsky. 1985. Inhibition of rat cervical epithelial cell growth by heparin and its reversal by EGF. J. Cell. Physiol. 125:499-506.
39. Ahmed, T., J. Garrigo, and I. Danta. 1993. Preventing bronchoconstriction in exercise-induced asthma with inhaled heparin. N. Engl. J. Med. 329:90-95.
40. Bowler, S. D., S. M. Smith, and P. S. Lavercombe. 1993. Heparin inhibits the immediate response to antigen in the skin and lungs of allergic subjects. Am. Rev. Respir. Dis. 147:160-163.
41. Rumyantseva, A. G., V. M. Kotel'nikov, M. Y. Rozkin, and V. S. Efimov. 1991. Response of the mast cell population to intratracheal injection of heparin and fucoidan. Bull. Exp. Biol. Med. 112:1612-1614.
42. Wilson, O., A. L. Jacobs, S. Stewart, and D. D. Carson. 1990. Expression of externally disposed heparin/heparan sulfate binding sites by uterine epithelial cells. J. Cell. Physiol. 143:60-67.
43. Heibert, L. M., and N. M. McDuffie. 1990. The internalization and release of heparin by cultured endothelial cells: the process is cell source, heparin source, time and concentration dependant. Artery 17:107-118.
44. Tsai, M., T. Takeishi, H. Thompson, K. E. Langley, K. M. Zsebo, D. D. Metcalfe, E. N. Geissler, and S. J. Galli. 1991. Induction of mast cell proliferation, maturation and heparin synthesis by the rat c-kit ligand, stem cell factor. Proc. Natl. Acad. Sci. U.S.A. 88:6382-6386.
45. 2+ influx through receptor-mediated activation of nonspecific cation channels in mast cells. Proc. Natl. Acad. Sci 90:3068-3072.
46. Hoth, M., and R. Penner. 1992. Depletion of intracellular calcium stores activates a calcium current in mast cells. Nature 355:353-355.
47. Smith, C. D., D. Wen, S. L. Mooberry, and K. J. Chang. 1992. Inhibitor of phosphatidylinositol 4-phosphate kinase by heparin. A possible mechanism for the antiproliferative effects of heparin. Biochem. J. 281:803-808.
48. Hunt, T. C., A. M. Campbell, C. Robinson, and S. T. Holgate. 1991. Structural and secretory characteristics of bovine lung and skin mast cells: evidence for the existence of heterogeneity. Clin. Exp. Allergy 21:173-182.