Efficient synthesis of (S)-4(5)-[1-(2,3-dimethylphenyl) ethyl]imidazole tartrate, the potent α2 adrenoceptor agonist dexmedetomidine

Synthetic Communications

Volumn 26, Issue 8, 1996, Pages 1585-1593

  Cordi, Alex A ^a   Persigand, Thierry ^a   Lecouvé, Jean Pierre ^b  

^a INSTITUT DE RECHERCHES SERVIER   (France)

^b ORIL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DEXMEDETOMIDINE; MEDETOMIDINE;

ARTICLE; CHIRALITY; DRUG PURIFICATION; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0029919060     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397919608003527     Document Type: Article

References (10)

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4. Karjalainen, A.J.; Pohjala, E.K.; Kurkela, K.O.A. UK Patent Application GB 2 101 114 (1983); Chem. Abstr. 1983, 99, 38462j.
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9. Carey, F.A.; Tremper, H.S. J. Org. Chem. 1971, 36, 758.
10. Jacques, J.; Collet, A.; Wilen, S.H. In Enantiomers, Racemates and Resolutions; Wiley-Interscience; New York 1981, 307-317.