The kinetics of repair of sublethal radiation-induced damage in pig skin: Studies with multiple interfraction intervals

Radiation Research

Volumn 145, Issue 5, 1996, Pages 586-594

  Van Den Aardweg, G J M J ^a,c   Hopewell, J W ^a   Guttenberger, R ^b  

^a CHURCHILL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF FREIBURG   (Germany)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL KINETICS; DOSE TIME EFFECT RELATION; FEMALE; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE FRACTIONATION; RADIATION INJURY; REPRODUCIBILITY; SKIN DEFECT; SWINE; TISSUE REPAIR;

ANIMALS; BETA RAYS; DOSE-RESPONSE RELATIONSHIP, RADIATION; EPIDERMIS; FEMALE; KINETICS; PROBABILITY; RADIATION TOLERANCE; SKIN; STRONTIUM; SWINE; TIME FACTORS; YTTRIUM RADIOISOTOPES;

ANIMALIA; SUS SCROFA;

EID: 0029919006     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579277     Document Type: Article

References (31)

1. J. F. Edsmyr, L. Andersson, P. L. Esposti, B. Littbrand and B. Nilsson, Irradiation therapy with muitiple small fractions per day in urinary bladder cancer. Radiother. Oncol. 4, 197-203 (1985).
2. M. I. Saunders and S. Dische, Radiotherapy employing three fractions in each day over a continuous period of 12 days. Br. J. Radiol. 59, 523-525 (1986).
3. M. I. Saunders, S. Dische, J. F. Fowler, J. Denekamp, E. P. Dunphy, E. J. Grosch, D. C. Fremont, R. F. U. Ashford, J. Maher and C Des Rochers, Radiotherapy employing 3 fractions on each of 12 consecutive days. Acta Oncol. 27, 163-167 (1988).
4. D. Gonzalez Gonzalez, K. Breur and E. van der Schueren, Preliminary results in advanced head and neck cancer with radiotherapy by multiple fractions a day. Clin. Radiol. 31, 417-421 (1980).
5. G. Peracchia and C. Salti, Radiotherapy with thrice-a-day fractionation in a short overall time: Clinical experiences. Int. J. Radiat. Oncol. Biol. Phys. 7, 99-104 (1981).
6. V. H. J. Svoboda, J. Krawczyk and A. Krawczyk, Seventeen years experience with accelerated radiotherapy for carcinoma of the breast. Int. J. Radiat. Oncol. Biol. Phys. 24, 65-71 (1992).
7. S. Dische and M. I. Saunders, Continuous, hyperfractionated accelerated radiotherapy (CHART): an interim report upon late morbidity. Radiother. Oncol. 16, 65-72 (1989).
8. L. Vanuytsel, K. K. Ang, L. Vandenbussche, R. Vereecken and E. van der Schueren, Radiotherapy in multiple fractions per day for prostatic carcinoma: late complications. Int. J. Radiat. Oncol. Biol. Phys. 12, 1589-1595 (1986).
9. H. D. Thames, An "incomplete repair" model for survival after fractionated and continuous irradiations. Int. J. Radiat. Biol. 47, 319-339 (1985).
10. R. G. Dale, The application of the linear-quadratic models to fractionated radiotherapy when there is incomplete normal tissue recovery between fractions, and possible implications for treatments involving multiple fractions per day. Br. J. Radiol. 59, 919-927 (1986).
11. R. Oliver, A comparison of the effects of acute and protracted gamma radiation on the growth of seedlings of Vicia faba. Int. J. Radiat. Biol. 8, 475-488 (1964).
12. J. W. Hopewell and G. J. M. J. van den Aardweg, Current concepts of dose fractionation in radiotherapy. Normal tissue tolerance. Br. J. Radiol. Suppl. 22, 88-94 (1988).
13. G. J. M. J. van den Aardweg and J. W. Hopewell, The kinetics of repair for radiation-induced sublethal damage in the pig epidermis: an interpretation based on a fast and a slow component of repair. Radiother. Oncol. 23, 94-104 (1992).
14. K. K. Ang, G. L. Jiang, R. Guttenberger, H. D. Thames, L. C. Stephens, C. D. Smith and Y. Feng, Impact of spinal cord repair kinetics on the practice of altered fractionation schedules. Radiother. Oncol. 25, 287-294 (1992).
15. W. T. Millar and P. A. Canney, The derivation and application of equations describing the effect of fractionated protracted irradiation, based on multiple and incomplete repair processes: Part 2 - Analysis of mouse lung data. Int. J. Radiat. Biol. 64, 292-303 (1993).
16. E. van Rongen, H. D. Thames and E. L. Travis, Recovery from radiation damage in mouse lung: Interpretation in terms of two rates of repair. Radiat. Res. 133, 225-233 (1993).
17. W. T. Millar, Y. M. Jen, J. H. Hendry and P. A. Canney, Two components of repair in irradiated kidney colony forming cells. Int. J Radiat Biol. 66, 189-196 (1994).
18. I. Turesson and H. D. Thames, Repair capacity and kinetics of human skin during fractionated radiotherapy: erythema, desquamation, and telangiectasia after 3 and 5 years follow-up. Radiother. Oncol. 15, 169-188 (1989).
19. G. J. M. J. van den Aardweg and J. W. Hopewell, Manipulation of the radiosensitivity of pig epidermis by changing the concentration of oxygen and halothane in the anaesthetic gas mixture. Int. J. Radiat. Biol. 56, 1023-1032 (1989).
20. G. J. M. J. van den Aardweg, M. Arnold and J. W. Hopewell, A comparison of the radiation response of the epidermis in two strains of pig. Radiat. Res. 124, 283-287 (1990).
21. J. W. Hopewell and G. J. M. J. van den Aardweg, Radiobiological studies with pig skin. Int. J. Radiat. Oncol. Biol. Phys. 14, 1047-1050 (1988).
22. G. J. M. J. van den Aardweg, J. W. Hopewell and R. H. Simmonds, Repair and recovery in the epithelial and vascular connective tissue of pig skin after irradiation. Radiother. Oncol. 11, 73-82 (1988).
23. R. Guttenberger, H. D. Thames and K. K. Ang, Is the experience with CHART compatible with experimental data? A new model of repair kinetics and computer simulations. Radiother. Oncol. 25, 280-286 (1992).
24. J. W. Hopewell and G. J. M. J. van den Aardweg, Studies of dose fractionation on early and late responses in pig skin: A re-appraisal of the importance of the overall treatment time and its effects on radiosensitisation and incomplete repair. Int. J. Radiat. Oncol. Biol. Phys. 21, 1441-1450 (1991).
25. H. D. Thames, Repair kinetics in tissues: alternative models. Radiother. Oncol. 14, 321-327 (1989).
26. A. Rojas, M. C. Joiner and H. Johns, Recovery kinetics of X-ray damage in mouse skin: the influence of dose per fraction. Int. J. Radiat. Biol. 59, 517-536 (1991).
27. J. F. Fowler, C. A. Whitsed and M. C. Joiner, Repair kinetics in mouse lung: a fast component at 1.1 Gy per fraction. Int. J. Radiat. Biol. 56, 335-353 (1989).
28. E. van Rongen, H. T. Madhuizen, C. H. T. Tan, S. K. Durham and M. J. J. Gijbels, Early and late effects of fractionated irradiation and the kinetics for repair in rat lung. Radiother. Oncol. 17, 323-337 (1990).
29. E. L. Travis, H. D. Thames, T. L. Watkins and I. Kiss, The kinetics of repair in mouse lung after fractionated irradiation. Int. J. Radiat. Biol. 52, 903-919 (1987).
30. W. T. Millar and P. A. Canney, The derivation and application of equations describing the effect of fractionated protracted irradiation, based on multiple and incomplete repair processes: Part I - Derivation of the equations. Int. J. Radiat. Biol. 64, 275-291 (1993).
31. W. T. Millar, G. J. M. J. van den Aardweg, J. W. Hopewell and P. A Canney, Repair kinetics in pig epidermis: an analysis based on two separate rates of repair. Int. J. Radiat. Biol. 69, 123-140 (1996).