Interspecies scaling: Predicting pharmacokinetic parameters of antiepileptic drugs in humans from animals with special emphasis on clearance

Journal of Pharmaceutical Sciences

Volumn 85, Issue 4, 1996, Pages 411-414

  Mahmood, Iftekhar ^a   Balian, John Dikran ^b  

^a Off Clin Pharmacol Biopharmaceut   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; DIAZEPAM; ETHOSUXIMIDE; PHENYTOIN; PROGABIDE; TOPIRAMATE; VALPROIC ACID; ZONISAMIDE;

ANIMAL; ARTICLE; BODY WEIGHT; BRAIN WEIGHT; CALCULATION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; HUMAN; LIFESPAN; NONHUMAN; PHARMACOKINETICS; SPECIES DIFFERENCE;

EID: 0029918773     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js950400y     Document Type: Article

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