-
1
-
-
0023187085
-
Clinical Pharmacokinetics of 5-Fluorouracil and its Metabolism in Plasma, Urine, and Bile
-
Heggie GD, Sommadossi J-P, Cross DS, Huster WJ and Diasio RB: Clinical Pharmacokinetics of 5-Fluorouracil and its Metabolism in Plasma, Urine, and Bile. Cancer Res 47; 2203-2206, 1987.
-
(1987)
Cancer Res
, vol.47
, pp. 2203-2206
-
-
Heggie, G.D.1
Sommadossi, J.-P.2
Cross, D.S.3
Huster, W.J.4
Diasio, R.B.5
-
2
-
-
0025774575
-
Inhibition of fluoropyrimidine catabolism by benzyloxybenzyluracil
-
Daher GC, Naguib FNM. el Kouni MH, Zhang R, Soong SJ and Diasio, RB: Inhibition of fluoropyrimidine catabolism by benzyloxybenzyluracil. Biochem Pharmacol 41: 1887-1893, 1991.
-
(1991)
Biochem Pharmacol
, vol.41
, pp. 1887-1893
-
-
Daher, G.C.1
Naguib, F.N.M.2
El Kouni, M.H.3
Zhang, R.4
Soong, S.J.5
Diasio, R.B.6
-
3
-
-
0023883431
-
Enhancing effect of bromovinyldeoxyuridine on antitumour activity of 5-fluorouracil against adenocarcinoma 755 in mice
-
Iigo M, Araki E, Nakajima Y, Hoshi A and De Clercq E: Enhancing effect of bromovinyldeoxyuridine on antitumour activity of 5-fluorouracil against adenocarcinoma 755 in mice. Biochem Pharmacol 37: 1609-1613, 1988.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 1609-1613
-
-
Iigo, M.1
Araki, E.2
Nakajima, Y.3
Hoshi, A.4
De Clercq, E.5
-
4
-
-
0027135995
-
5-Ethynyluracl (776C85): Inactivation of dihydropyrimidine dehydrogenase in vivo
-
Spector T, Harrington JA and Porter DJT. 5-Ethynyluracl (776C85): inactivation of dihydropyrimidine dehydrogenase in vivo. Biochem Pharmacol 46: 2243-2248, 1993.
-
(1993)
Biochem Pharmacol
, vol.46
, pp. 2243-2248
-
-
Spector, T.1
Harrington, J.A.2
Porter, D.J.T.3
-
5
-
-
0023902287
-
Familial Deficiency of Dihydropyrimidine Dehydrogenase, Biochemical Basis for Familial Pyrimidinemia and Severe 5-Fluorouracil-induced Toxicity
-
Diasio RB, Beavers TL and Carpenter JT: Familial Deficiency of Dihydropyrimidine Dehydrogenase, Biochemical Basis for Familial Pyrimidinemia and Severe 5-Fluorouracil-induced Toxicity. J Clin Invest 81: 47-51, 1988.
-
(1988)
J Clin Invest
, vol.81
, pp. 47-51
-
-
Diasio, R.B.1
Beavers, T.L.2
Carpenter, J.T.3
-
6
-
-
0025990479
-
Severe 5-Fluorouracil Toxicity Secondary to Dihydropyrimidine Dehydrogenase Deficiency
-
Harris BE, Carpenter JT and Diasio RB. Severe 5-Fluorouracil Toxicity Secondary to Dihydropyrimidine Dehydrogenase Deficiency. Cancer 68: 499-501, 1991.
-
(1991)
Cancer
, vol.68
, pp. 499-501
-
-
Harris, B.E.1
Carpenter, J.T.2
Diasio, R.B.3
-
7
-
-
0027409335
-
Severe 5-Fluorouracil Toxicity in a Patient with Decreased Dihydropyrimidine Dehydrogenase Activity
-
Lyss AP, Lilenbaum RC, Harris BE and Diasio RB: Severe 5-Fluorouracil Toxicity in a Patient with Decreased Dihydropyrimidine Dehydrogenase Activity. Cancer Invest 11: 239-240, 1993.
-
(1993)
Cancer Invest
, vol.11
, pp. 239-240
-
-
Lyss, A.P.1
Lilenbaum, R.C.2
Harris, B.E.3
Diasio, R.B.4
-
8
-
-
0028813120
-
Human Polymorphism in Drug Metabolism: Mutation in the Dihydropyrimidine Dehydrogenase Gene Results in Exon Skipping and Thymine Uraciluria
-
Meinsma R, Fernandez - Salguero P, Van Kuilenburg ABP, Van Gennip AH and Gonzalez FJ: Human Polymorphism in Drug Metabolism: Mutation in the Dihydropyrimidine Dehydrogenase Gene Results in Exon Skipping and Thymine Uraciluria. DNA Cell Biol 14: 1-6, 1995.
-
(1995)
DNA Cell Biol
, vol.14
, pp. 1-6
-
-
Meinsma, R.1
Fernandez - Salguero, P.2
Van Kuilenburg, A.B.P.3
Van Gennip, A.H.4
Gonzalez, F.J.5
-
9
-
-
0019876538
-
Purification and Properties of Dihydropyrimidine Dehydrogenase from Rat Liver
-
Shiotani T and Weber G: Purification and Properties of Dihydropyrimidine Dehydrogenase from Rat Liver. J Biol Chem 256: 219-224, 1981.
-
(1981)
J Biol Chem
, vol.256
, pp. 219-224
-
-
Shiotani, T.1
Weber, G.2
-
10
-
-
0024472695
-
Purification and characterisation of dihydropyrimidine dehydrogenase from pig liver
-
Podschun B, Wahler G and Schnackerz KD: Purification and characterisation of dihydropyrimidine dehydrogenase from pig liver. Eur J Biochem 185: 219-224, 1989.
-
(1989)
Eur J Biochem
, vol.185
, pp. 219-224
-
-
Podschun, B.1
Wahler, G.2
Schnackerz, K.D.3
-
11
-
-
0026793052
-
Purification and Characterisation of Dihydropyrimidine dehydrogenase from Human Liver
-
Lu Z-H, Zhang R and Diasio RB: Purification and Characterisation of Dihydropyrimidine dehydrogenase from Human Liver. J Biol Chem 267: 17102-17109, 1992.
-
(1992)
J Biol Chem
, vol.267
, pp. 17102-17109
-
-
Lu, Z.-H.1
Zhang, R.2
Diasio, R.B.3
-
12
-
-
0027297227
-
Comparison of Dihydropyrimidine dehydrogenase from human, rat, pig and cow liver
-
Lu Z-H, Zhang R and Diasioo RB: Comparison of Dihydropyrimidine dehydrogenase from human, rat, pig and cow liver. Biochem Pharmacol 46: 945-952, 1993.
-
(1993)
Biochem Pharmacol
, vol.46
, pp. 945-952
-
-
Lu, Z.-H.1
Zhang, R.2
Diasioo, R.B.3
-
13
-
-
0022400840
-
Enzymes of Uracil Catabolism in Normal and Neoplastic Human Tissues
-
Naguib FNM, el Kouni MH and Cha S: Enzymes of Uracil Catabolism in Normal and Neoplastic Human Tissues. Cancer Res 45: 5405-5412, 1985.
-
(1985)
Cancer Res
, vol.45
, pp. 5405-5412
-
-
Naguib, F.N.M.1
El Kouni, M.H.2
Cha, S.3
-
14
-
-
0022448330
-
Distribution and Inhibition of Dihydrouracil Dehydrogenase Activities in Human Tissues Using 5-Fluorouracil as a Substrate
-
Ho DH, Townsend L, Luna MA and Bodey GP: Distribution and Inhibition of Dihydrouracil Dehydrogenase Activities in Human Tissues Using 5-Fluorouracil as a Substrate. Anticancer Res 6: 781-784, 1986.
-
(1986)
Anticancer Res
, vol.6
, pp. 781-784
-
-
Ho, D.H.1
Townsend, L.2
Luna, M.A.3
Bodey, G.P.4
-
15
-
-
0015217925
-
Dihydrouracil Dehydrogenase of Rat Liver. Separation of Hydrogenases and Dehydrogenase Activities
-
Smith AE and Yamada EW: Dihydrouracil Dehydrogenase of Rat Liver. Separation of Hydrogenases and Dehydrogenase Activities. J Biol Chem 246: 3610-3617, 1971.
-
(1971)
J Biol Chem
, vol.246
, pp. 3610-3617
-
-
Smith, A.E.1
Yamada, E.W.2
-
16
-
-
0017240313
-
Pyrimidine reducing enzymes of rat liver
-
Hallock RO and Yamada EW: Pyrimidine reducing enzymes of rat liver. Can J Biochem 54. 178-184, 1976.
-
(1976)
Can J Biochem
, vol.54
, pp. 178-184
-
-
Hallock, R.O.1
Yamada, E.W.2
-
17
-
-
0028261564
-
Clinical and Biochemical Findings in Six Patients with Pyrimidine Degradation Defects
-
Van Gennip AH, Abeling NGGM, Stroomer AEM, Van Lenthe H and Bakker HD: Clinical and Biochemical Findings in Six Patients with Pyrimidine Degradation Defects. J Inher Metab Dis 17: 130-132, 1994.
-
(1994)
J Inher Metab Dis
, vol.17
, pp. 130-132
-
-
Van Gennip, A.H.1
Abeling, N.G.G.M.2
Stroomer, A.E.M.3
Van Lenthe, H.4
Bakker, H.D.5
-
18
-
-
0021810750
-
Nucleotide Profiles of Normal Blood Cells Determined by High-Performance Liquid Chromatography
-
De Korte D, Haverkort WA, Van Gennip AH and Roos D: Nucleotide Profiles of Normal Blood Cells Determined by High-Performance Liquid Chromatography. Anal Biochem 147: 197-209, 1985.
-
(1985)
Anal Biochem
, vol.147
, pp. 197-209
-
-
De Korte, D.1
Haverkort, W.A.2
Van Gennip, A.H.3
Roos, D.4
-
19
-
-
0022186670
-
Measurement of Protein Using Bicinchoninic Acid
-
Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ and Klenk DC: Measurement of Protein Using Bicinchoninic Acid. Anal Biochem 150: 76-85, 1985.
-
(1985)
Anal Biochem
, vol.150
, pp. 76-85
-
-
Smith, P.K.1
Krohn, R.I.2
Hermanson, G.T.3
Mallia, A.K.4
Gartner, F.H.5
Provenzano, M.D.6
Fujimoto, E.K.7
Goeke, N.M.8
Olson, B.J.9
Klenk, D.C.10
-
20
-
-
0023841231
-
Pyrimidine Base Degradation in Cultured Murine C-1300 Neuroblastoma Cells and in Situ Tumours
-
Tuchman M, O' Dea RF, Ramnaraine MLR and Mirkin BL. Pyrimidine Base Degradation in Cultured Murine C-1300 Neuroblastoma Cells and in Situ Tumours. J Clin Invest 81: 425-430, 1988.
-
(1988)
J Clin Invest
, vol.81
, pp. 425-430
-
-
Tuchman, M.1
O' Dea, R.F.2
Ramnaraine, M.L.R.3
Mirkin, B.L.4
-
21
-
-
0024399344
-
Dihydropyrimidine Dehydrogenase Activity in Human Blood Mononuclear Cells
-
Tuchman M, Roemeling RV, Hrushesky WAM, Sothern RB and O' Dea RF: Dihydropyrimidine Dehydrogenase Activity in Human Blood Mononuclear Cells. Enzyme 42: 15-24, 1989.
-
(1989)
Enzyme
, vol.42
, pp. 15-24
-
-
Tuchman, M.1
Roemeling, R.V.2
Wam, H.3
Sothern, R.B.4
O' Dea, R.F.5
-
22
-
-
0017855795
-
Estimation of michaelis constant and maximum velocity from the direct linear plot
-
Cornisch - Bowden A and Eisenthal R: Estimation of michaelis constant and maximum velocity from the direct linear plot. Biochim Biophys Acta 523: 268-272, 1978.
-
(1978)
Biochim Biophys Acta
, vol.523
, pp. 268-272
-
-
Cornisch - Bowden, A.1
Eisenthal, R.2
-
24
-
-
0028102536
-
Dehalogenating and NADPH-modifying Activities of Dihydropyrimidine Dehydrogenase
-
Porter DJT: Dehalogenating and NADPH-modifying Activities of Dihydropyrimidine Dehydrogenase. J Biol Chem 269: 24177-24182, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 24177-24182
-
-
Porter, D.J.T.1
-
25
-
-
0028069815
-
The Conversion of Xanthine Dehydrogenase to Xanthine Oxidase and the Role of the Enzyme in Reperfusion Injury
-
Nishino T: The Conversion of Xanthine Dehydrogenase to Xanthine Oxidase and the Role of the Enzyme in Reperfusion Injury. J Biochem 116. 1-6, 1994.
-
(1994)
J Biochem
, vol.116
, pp. 1-6
-
-
Nishino, T.1
-
26
-
-
0028027180
-
cDNA Cloning and Chromosome Mapping of Human Dihydropyrimidine Dehydrogenase, an Enzyme Associated with 5-Fluorouracil Toxicity and Congenital Thymine Uraciluria
-
Yokota H, Fernandez - Salguero P, Furuya H, Lin K, McBride OW, Podschun B, Schnackerz KD and Gonzalez FJ: cDNA Cloning and Chromosome Mapping of Human Dihydropyrimidine Dehydrogenase, an Enzyme Associated with 5-Fluorouracil Toxicity and Congenital Thymine Uraciluria. J Biol Chem 269: 23192-23196, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 23192-23196
-
-
Yokota, H.1
Fernandez - Salguero, P.2
Furuya, H.3
Lin, K.4
McBride, O.W.5
Podschun, B.6
Schnackerz, K.D.7
Gonzalez, F.J.8
-
27
-
-
0017122896
-
Degradation of Purines and Pyrimidines by Micro-organisms
-
Vogels GD and Van der Drift C: Degradation of Purines and Pyrimidines by Micro-organisms. Bacterial Rev 40: 403-468, 1976.
-
(1976)
Bacterial Rev
, vol.40
, pp. 403-468
-
-
Vogels, G.D.1
Van Der Drift, C.2
-
28
-
-
0026043729
-
Isolation and characterisation of a dihjydropyrimidine dehydrogenase mutant of Pseudomonas chloroaphis
-
West TP: Isolation and characterisation of a dihjydropyrimidine dehydrogenase mutant of Pseudomonas chloroaphis. Arch Microbiol 156: 513-516, 1991.
-
(1991)
Arch Microbiol
, vol.156
, pp. 513-516
-
-
West, T.P.1
-
29
-
-
0026470199
-
Reductive catabolism of pyrimidine bases by Pseudomonas stutzeri
-
Xu G and West TP: Reductive catabolism of pyrimidine bases by Pseudomonas stutzeri. J Gen Microbiol 138: 2459-2463, 1992.
-
(1992)
J Gen Microbiol
, vol.138
, pp. 2459-2463
-
-
Xu, G.1
West, T.P.2
-
30
-
-
0028567197
-
Pyrimidine ribonucleoside catabolic enzyme activities of Pseudomonas picketti
-
West TP: Pyrimidine ribonucleoside catabolic enzyme activities of Pseudomonas picketti. Antonie van Leeuwenhoek 66: 307-312, 1994.
-
(1994)
Antonie van Leeuwenhoek
, vol.66
, pp. 307-312
-
-
West, T.P.1
-
31
-
-
0018788267
-
Pyrimidine-degrading enzymes. Purification and properties of β-ureidopropionase of euglena graciles
-
Wasternack C, Lippmann G and Reinbotte H: Pyrimidine-degrading enzymes. Purification and properties of β-ureidopropionase of euglena graciles. Biochim Biophys Acata 570: 341-351, 1979.
-
(1979)
Biochim Biophys Acata
, vol.570
, pp. 341-351
-
-
Wasternack, C.1
Lippmann, G.2
Reinbotte, H.3
-
32
-
-
0020674613
-
β-Alanine upatake by mouse brain slices
-
Kontro P: β-Alanine upatake by mouse brain slices. Neuroscience 8: 153-159, 1983.
-
(1983)
Neuroscience
, vol.8
, pp. 153-159
-
-
Kontro, P.1
-
33
-
-
0021713592
-
β-Alamine transport into plasma membrane vesicles derived from rat brain synaptosomes
-
Zafra F, Aragon MC, Valdivieso F and Gimenez C: β-Alamine transport into plasma membrane vesicles derived from rat brain synaptosomes. Neurochem Res 9: 695-707, 1984.
-
(1984)
Neurochem Res
, vol.9
, pp. 695-707
-
-
Zafra, F.1
Aragon, M.C.2
Valdivieso, F.3
Gimenez, C.4
-
34
-
-
0022613107
-
High-affinity uptake of taurine and β-alanine in primary cultures of rat astrocytes
-
Holopainen I and Kontro P: High-affinity uptake of taurine and β-alanine in primary cultures of rat astrocytes. Neurochem Res 11: 207-215, 1985.
-
(1985)
Neurochem Res
, vol.11
, pp. 207-215
-
-
Holopainen, I.1
Kontro, P.2
|