메뉴 건너뛰기




Volumn 15, Issue 2, 1996, Pages 144-153

Alterations in transforming growth factor-α and epidermal growth factor receptor expression during rat esophageal tumorigenesis

Author keywords

Chemical carcinogenesis; Gene expression; Papilloma; Preneoplastic

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 0029917811     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2744(199602)15:2<144::AID-MC7>3.0.CO;2-J     Document Type: Article
Times cited : (35)

References (51)
  • 2
    • 0000226889 scopus 로고
    • A study of etiology factors in cancer of esophagus
    • Wynder EL, Bross IJ. A study of etiology factors in cancer of esophagus Cancer 14.389-413, 1961.
    • (1961) Cancer , vol.14 , pp. 389-413
    • Wynder, E.L.1    Bross, I.J.2
  • 4
    • 0018902754 scopus 로고
    • Research on esophageal cancer in China: A review
    • Yang CS Research on esophageal cancer in China: A review. Cancer Res 40:2633-2644, 1980
    • (1980) Cancer Res , vol.40 , pp. 2633-2644
    • Yang, C.S.1
  • 5
    • 0002251794 scopus 로고
    • Some aspects of the epidemiology and etiology of esophageal cancer with particular emphasis on the Transkei, South Africa
    • Warwick GP, Harington JS. Some aspects of the epidemiology and etiology of esophageal cancer with particular emphasis on the Transkei, South Africa. Adv Cancer Res 17:81-229, 1973.
    • (1973) Adv Cancer Res , vol.17 , pp. 81-229
    • Warwick, G.P.1    Harington, J.S.2
  • 6
    • 0002450223 scopus 로고
    • Organospecific carcinogenesis in the digestive tract
    • Nakahara W, Takayama S, Sugimura T, et al. (eds), University Park Press, Baltimore
    • Druckrey H Organospecific carcinogenesis in the digestive tract. In: Nakahara W, Takayama S, Sugimura T, et al. (eds), Topics in Chemical Carcinogenesis University Park Press, Baltimore, 1972, pp. 73-101
    • (1972) Topics in Chemical Carcinogenesis , pp. 73-101
    • Druckrey, H.1
  • 7
    • 0025304093 scopus 로고
    • Mutational activation of the cellular Harvey ras oncogene in rat esophageal papillomas induced by methylbenzylnitrosamine
    • Wang Y, You M, Reynolds SH, Stoner GD, Anderson MW. Mutational activation of the cellular Harvey ras oncogene in rat esophageal papillomas induced by methylbenzylnitrosamine Cancer Res 50-1591-1595, 1990
    • (1990) Cancer Res , vol.50 , pp. 1591-1595
    • Wang, Y.1    You, M.2    Reynolds, S.H.3    Stoner, G.D.4    Anderson, M.W.5
  • 8
    • 0026041456 scopus 로고
    • Incidence of Harvey ras oncogene point mutations and their expression in methylbenzylnitrosamine-indueed esophageal tumongenesis
    • Barch DH, Jacoby RF, Brasitus TA, Radosevich JA, Carney WP, lannaccone PM. Incidence of Harvey ras oncogene point mutations and their expression in methylbenzylnitrosamine-indueed esophageal tumongenesis. Carcinogenesis 12:2373-2377, 1991.
    • (1991) Carcinogenesis , vol.12 , pp. 2373-2377
    • Barch, D.H.1    Jacoby, R.F.2    Brasitus, T.A.3    Radosevich, J.A.4    Carney, W.P.5    Lannaccone, P.M.6
  • 9
    • 0028003037 scopus 로고
    • Mutations in p53 and Ha-ras genes in esophageal papillomas induced by N-nitrosomethylbenzylamine in two strains of rats
    • Lozano J-C, Nakazawa H, Cros M-P, Cabrai R, Yamasaki H G-A mutations in p53 and Ha-ras genes in esophageal papillomas induced by N-nitrosomethylbenzylamine in two strains of rats. Mol Carcinog 9 33-39, 1994.
    • (1994) Mol Carcinog , vol.9 , pp. 33-39
    • Lozano, J.-C.1    Nakazawa, H.2    Cros, M.-P.3    Cabrai, R.4    Yamasaki, H.G.-A.5
  • 10
    • 0345562434 scopus 로고
    • Chemoprevention of esophageal cancer by ellagic acid and phenethyl isothiocyanate
    • Wattenberg LW, Lipkin M, Boone CW, Kelloff GJ (eds), CRC Press, Inc., Boca Raton, FL
    • Stoner GD, Mandal-Chaudhuri S, Daniel EM, Heur Y-H, Morrissey DT Chemoprevention of esophageal cancer by ellagic acid and phenethyl isothiocyanate In: Wattenberg LW, Lipkin M, Boone CW, Kelloff GJ (eds), Cancer Chemoprevention. CRC Press, Inc., Boca Raton, FL, 1992, pp 407-439
    • (1992) Cancer Chemoprevention , pp. 407-439
    • Stoner, G.D.1    Mandal-Chaudhuri, S.2    Daniel, E.M.3    Heur, Y.-H.4    Morrissey, D.T.5
  • 11
    • 0023807364 scopus 로고
    • Transforming growth factor α
    • Derynck R Transforming growth factor α Cell 54-593-595, 1988.
    • (1988) Cell , vol.54 , pp. 593-595
    • Derynck, R.1
  • 12
    • 0024306478 scopus 로고
    • Induction of c-fos and c-myc proto-oncogene expression by epidermal growth factor and transforming growth factor alpha is calcium independent
    • Cutry AF, Kinniburgh AJ, Krabak MJ, Hui S-W, Wenner CE. Induction of c-fos and c-myc proto-oncogene expression by epidermal growth factor and transforming growth factor alpha is calcium independent. J Biol Chem 264:19700-19705, 1989
    • (1989) J Biol Chem , vol.264 , pp. 19700-19705
    • Cutry, A.F.1    Kinniburgh, A.J.2    Krabak, M.J.3    Hui, S.-W.4    Wenner, C.E.5
  • 13
    • 0002873953 scopus 로고
    • Transforming growth factor-alpha as a possible autocrine growth factor for human adenocarcinoma of the lung
    • Imura H, Shizume K, Yoshida S (eds), Excerpta Medica, New York
    • Imanishi K, Yamaguchi K, Honda S, Abe K. Transforming growth factor-alpha as a possible autocrine growth factor for human adenocarcinoma of the lung. In Imura H, Shizume K, Yoshida S (eds), Progress in Endocrinology, Vol. 2 Excerpta Medica, New York, 1988, pp 1363-1368.
    • (1988) Progress in Endocrinology , vol.2 , pp. 1363-1368
    • Imanishi, K.1    Yamaguchi, K.2    Honda, S.3    Abe, K.4
  • 14
    • 0024551794 scopus 로고
    • Transforming growth factor alpha production and epidermal growth factor receptor expression in normal and oncogene transformed human mammary epithelial cells
    • Valverius EM, Bates SE, Stampfer MR, et al. Transforming growth factor alpha production and epidermal growth factor receptor expression in normal and oncogene transformed human mammary epithelial cells. Mol Endocrinol 3:203-214, 1989
    • (1989) Mol Endocrinol , vol.3 , pp. 203-214
    • Valverius, E.M.1    Bates, S.E.2    Stampfer, M.R.3
  • 15
    • 0023449818 scopus 로고
    • Production of transforming growth factor alpha in human pancreatic cancer cells: Evidence for a superagonist autocrine cycle
    • Smith JJ, Derynck R, Korc M. Production of transforming growth factor alpha in human pancreatic cancer cells: Evidence for a superagonist autocrine cycle Proc Natl Acad Sci USA 84 7567-7570, 1987.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7567-7570
    • Smith, J.J.1    Derynck, R.2    Korc, M.3
  • 16
    • 0025128587 scopus 로고
    • Expression of epidermal growth factor, transforming growth factor-alpha and their receptor genes in human gastric carcinomas: Implication for autocrine growth
    • Yoshida O, Kyo E, Tsujino T, Sano T, Niimoto M, Tahara E. Expression of epidermal growth factor, transforming growth factor-alpha and their receptor genes in human gastric carcinomas: Implication for autocrine growth. Jpn J Cancer Res 81:43-51, 1990
    • (1990) Jpn J Cancer Res , vol.81 , pp. 43-51
    • Yoshida, O.1    Kyo, E.2    Tsujino, T.3    Sano, T.4    Niimoto, M.5    Tahara, E.6
  • 17
    • 0025103246 scopus 로고
    • EGF andTGF-alpha, the ligands of hyperproduced EGFR in human esophageal carcinoma cells, act as autocrine growth factors
    • Yoshida K, Kyo E, Tsuda T, et al. EGF andTGF-alpha, the ligands of hyperproduced EGFR in human esophageal carcinoma cells, act as autocrine growth factors, Int J Cancer 45.131-135, 1990.
    • (1990) Int J Cancer , vol.45 , pp. 131-135
    • Yoshida, K.1    Kyo, E.2    Tsuda, T.3
  • 19
    • 0027767476 scopus 로고
    • Targeted overexpression of transforming growth factor α in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas
    • Dominey AM, Wang X-J, King LE Jr, et al Targeted overexpression of transforming growth factor α in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas. Cell Growth Differ 4 1071-1082, 1993
    • (1993) Cell Growth Differ , vol.4 , pp. 1071-1082
    • Dominey, A.M.1    Wang, X.-J.2    King Jr., L.E.3
  • 20
    • 0025297086 scopus 로고
    • Overexpression of TGFα in transgenic mice. Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast
    • Sandgren EP, Luetteke NC, Palmiter RD, Brinster RL, Lee DC. Overexpression of TGFα in transgenic mice. Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast Cell 61:1121-1135, 1990.
    • (1990) Cell , vol.61 , pp. 1121-1135
    • Sandgren, E.P.1    Luetteke, N.C.2    Palmiter, R.D.3    Brinster, R.L.4    Lee, D.C.5
  • 21
    • 0025341727 scopus 로고
    • TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas
    • Jhappan C, Stahle C, Harkins RN, Fausto N, Smith GH, Merlino GT. TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas. Cell 61.1137-1146, 1990.
    • (1990) Cell , vol.61 , pp. 1137-1146
    • Jhappan, C.1    Stahle, C.2    Harkins, R.N.3    Fausto, N.4    Smith, G.H.5    Merlino, G.T.6
  • 22
    • 0024367513 scopus 로고
    • Anti-epidermal growth factor receptor antibodies inhibit the autocrine-stimulated growth of MDA-468 human breast cancer cells
    • Ennis BW, Valverius EM, Bates SE, et al. Anti-epidermal growth factor receptor antibodies inhibit the autocrine-stimulated growth of MDA-468 human breast cancer cells. Mol Endocrinol 3:1830-1838,1989
    • (1989) Mol Endocrinol , vol.3 , pp. 1830-1838
    • Ennis, B.W.1    Valverius, E.M.2    Bates, S.E.3
  • 23
    • 0025094161 scopus 로고
    • Monoclonal antibody 425 inhibits growth stimulation of carcinoma cells by exogenous EGF and tumor-derived EGF/TGF-alpha
    • Rodeck U, Noel W, Murthy U, Herlyn M. Monoclonal antibody 425 inhibits growth stimulation of carcinoma cells by exogenous EGF and tumor-derived EGF/TGF-alpha. J Cell Biochem 44 69-79, 1990.
    • (1990) J Cell Biochem , vol.44 , pp. 69-79
    • Rodeck, U.1    Noel, W.2    Murthy, U.3    Herlyn, M.4
  • 24
    • 0026029762 scopus 로고
    • Differential role of transforming growth factor-α in two human colon carcinoma cell lines
    • Watkins LF, Levine AE Differential role of transforming growth factor-α in two human colon carcinoma cell lines, Int J Cancer 47455-460, 1991.
    • (1991) Int J Cancer , vol.47 , pp. 455-460
    • Watkins, L.F.1    Levine, A.E.2
  • 25
    • 0023100052 scopus 로고
    • Synthesis of messenger RNAs for transforming growth factor α and β and the epidermal growth factor receptor by human tumors
    • Derynck R, Goeddel DV, Ullrich A, et al. Synthesis of messenger RNAs for transforming growth factor α and β and the epidermal growth factor receptor by human tumors Cancer Res 47:707-712, 1987
    • (1987) Cancer Res , vol.47 , pp. 707-712
    • Derynck, R.1    Goeddel, D.V.2    Ullrich, A.3
  • 26
    • 0026028343 scopus 로고
    • Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers
    • Gullick WJ. Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers. Br Med Bull 47 87-98, 1991.
    • (1991) Br Med Bull , vol.47 , pp. 87-98
    • Gullick, W.J.1
  • 27
    • 0025737543 scopus 로고
    • Altered regulation of TGFβ1 and TGFα in primary keratinocytes and papillomas expressing v-Haras
    • Glick AB, Sporn MB, Yuspa SH. Altered regulation of TGFβ1 and TGFα in primary keratinocytes and papillomas expressing v-Haras. Mol Carcinog 4:210-219, 1991.
    • (1991) Mol Carcinog , vol.4 , pp. 210-219
    • Glick, A.B.1    Sporn, M.B.2    Yuspa, S.H.3
  • 29
    • 0024230257 scopus 로고
    • Induction of transforming growth factor α expression in mouse mammary epithelial cells after transformation with a point-mutated c-Ha-ras protooncogene
    • Ciardiello F, Kim N, Hynes N, et al Induction of transforming growth factor α expression in mouse mammary epithelial cells after transformation with a point-mutated c-Ha-ras protooncogene. Mol Endocrinol 2.1202-1216, 1988.
    • (1988) Mol Endocrinol , vol.2 , pp. 1202-1216
    • Ciardiello, F.1    Kim, N.2    Hynes, N.3
  • 30
    • 0025490534 scopus 로고
    • Transforming growth factor-α expression is enhanced in human mammary epithelial cells transformed by an activated c-Ha-ras protooncogene but not by the c-neu protooncogene, and overexpression of the transforming growth factor-α complementary DNA leads to transformation
    • Gardiello F, McGeady ML, Kim N, et al Transforming growth factor-α expression is enhanced in human mammary epithelial cells transformed by an activated c-Ha-ras protooncogene but not by the c-neu protooncogene, and overexpression of the transforming growth factor-α complementary DNA leads to transformation. Cell Growth Differ 1:407-420, 1990.
    • (1990) Cell Growth Differ , vol.1 , pp. 407-420
    • Gardiello, F.1    McGeady, M.L.2    Kim, N.3
  • 31
    • 0026072372 scopus 로고
    • Ha-ras induction of invasive phenotype results in up-regulation of epidermal growth factor receptors and altered responsiveness to epidermal growth factor in human papillary transitional cell carcinoma cells
    • Theodorescu D, Cornil I, Sheehan C, Man MS, Kerbel RS. Ha-ras induction of invasive phenotype results in up-regulation of epidermal growth factor receptors and altered responsiveness to epidermal growth factor in human papillary transitional cell carcinoma cells Cancer Res 51.4486-4491, 1991.
    • (1991) Cancer Res , vol.51 , pp. 4486-4491
    • Theodorescu, D.1    Cornil, I.2    Sheehan, C.3    Man, M.S.4    Kerbel, R.S.5
  • 32
    • 0028034699 scopus 로고
    • Altered expression of the epidermal growth factor receptor and transforming growth factor-α during multistage skin carcinogenesis in SENCAR mice
    • Rho O, Beltrán LM, Gimenez-Conti IB, DiGiovanni J Altered expression of the epidermal growth factor receptor and transforming growth factor-α during multistage skin carcinogenesis in SENCAR mice Mol Carcinog 11.19-28, 1994
    • (1994) Mol Carcinog , vol.11 , pp. 19-28
    • Rho, O.1    Beltrán, L.M.2    Gimenez-Conti, I.B.3    DiGiovanni, J.4
  • 33
    • 0023274128 scopus 로고
    • Production and autoinduction of transforming growth factor-α in human keratinocytes
    • Coffey RJ Jr, Derynck R, Wilcox JN, et al Production and autoinduction of transforming growth factor-α in human keratinocytes Nature 328.817-820, 1987.
    • (1987) Nature , vol.328 , pp. 817-820
    • Coffey Jr., R.J.1    Derynck, R.2    Wilcox, J.N.3
  • 34
    • 0023654798 scopus 로고
    • Epidermal growth factor receptor synthesis is stimulated by phorbol ester and epidermal growth factor
    • Bjorge JD, Kudlow JE Epidermal growth factor receptor synthesis is stimulated by phorbol ester and epidermal growth factor. J Biol Chem 262 6615-6622, 1987
    • (1987) J Biol Chem , vol.262 , pp. 6615-6622
    • Bjorge, J.D.1    Kudlow, J.E.2
  • 35
    • 0026078008 scopus 로고
    • Immunohistologic detection of the epidermal growth factor receptor in human esophageal squamous cell carcinoma
    • Yano H, Shiozaki H, Kobayashi D, et al. Immunohistologic detection of the epidermal growth factor receptor in human esophageal squamous cell carcinoma. Cancer 67:91-98, 1991,
    • (1991) Cancer , vol.67 , pp. 91-98
    • Yano, H.1    Shiozaki, H.2    Kobayashi, D.3
  • 36
    • 0027771838 scopus 로고
    • Correlation of p53 mutations with epidermal growth factor receptor overexpression and absence of mdm2 amplification in human esophageal carcinomas
    • Esteve A, Lehman T, Jiang W, et al Correlation of p53 mutations with epidermal growth factor receptor overexpression and absence of mdm2 amplification in human esophageal carcinomas. Mol Carcinog 8:306-311, 1993.
    • (1993) Mol Carcinog , vol.8 , pp. 306-311
    • Esteve, A.1    Lehman, T.2    Jiang, W.3
  • 38
    • 0027294912 scopus 로고
    • Amplification and overexpression of the EGFR and erbB-2 genes in human esophageal adenocaronomas
    • Al-Kasspooles M, Moore JH, Orringer MB, Beer DG. Amplification and overexpression of the EGFR and erbB-2 genes in human esophageal adenocaronomas Int J Cancer 54:213-219, 1993.
    • (1993) Int J Cancer , vol.54 , pp. 213-219
    • Al-Kasspooles, M.1    Moore, J.H.2    Orringer, M.B.3    Beer, D.G.4
  • 39
    • 0026593881 scopus 로고
    • Proliferating cell nuclear antigen in esophageal diseases: Correlation with transforming growth factor alpha expression
    • Jankowski J, McMenemin R, Yu C, Hopwood D, Wormsley KG. Proliferating cell nuclear antigen in esophageal diseases: Correlation with transforming growth factor alpha expression. Gut 33-587-591, 1992
    • (1992) Gut , vol.33 , pp. 587-591
    • Jankowski, J.1    McMenemin, R.2    Yu, C.3    Hopwood, D.4    Wormsley, K.G.5
  • 40
    • 0027183870 scopus 로고
    • Elevated levels of transforming growth factor α and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer
    • Grandis JR, Tweardy DJ. Elevated levels of transforming growth factor α and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer Cancer Res 533579-3584, 1993.
    • (1993) Cancer Res , vol.53 , pp. 3579-3584
    • Grandis, J.R.1    Tweardy, D.J.2
  • 41
    • 0028292482 scopus 로고
    • Dysregulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis
    • Shin DM, Ro JY, Hong WK, Hittelman WN. Dysregulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis. Cancer Res 54:3153-3159, 1994
    • (1994) Cancer Res , vol.54 , pp. 3153-3159
    • Shin, D.M.1    Ro, J.Y.2    Hong, W.K.3    Hittelman, W.N.4
  • 43
    • 0027098011 scopus 로고
    • Comparison between epidermal growth factor, transforming growth factor-α, and EGF receptor levels in regions of adult rat brain
    • Kaser MR, Lakshmanan J, Fisher DA Comparison between epidermal growth factor, transforming growth factor-α, and EGF receptor levels in regions of adult rat brain Mol Brain Res 16-316-322, 1992
    • (1992) Mol Brain Res , vol.16 , pp. 316-322
    • Kaser, M.R.1    Lakshmanan, J.2    Fisher, D.A.3
  • 44
    • 0025274445 scopus 로고
    • Characterization of the rat transforming growth factor alpha gene and identification of promoter sequences
    • Blasband AJ, Rogers KT, Chen X, Azizkhan JC, Lee DC. Characterization of the rat transforming growth factor alpha gene and identification of promoter sequences. Mol Cell Biol 10.2111-2121, 1990.
    • (1990) Mol Cell Biol , vol.10 , pp. 2111-2121
    • Blasband, A.J.1    Rogers, K.T.2    Chen, X.3    Azizkhan, J.C.4    Lee, D.C.5
  • 45
    • 0025368706 scopus 로고
    • A truncated, secreted form of the epidermal growth factor receptor is encoded by an alternatively spliced transcript in normal rat tissue
    • Petch LA, Harris J, Raymond VW, Blasband AJ, Lee DC, Earp HS. A truncated, secreted form of the epidermal growth factor receptor is encoded by an alternatively spliced transcript in normal rat tissue. Mol Cell Biol 10:2973-2982, 1990
    • (1990) Mol Cell Biol , vol.10 , pp. 2973-2982
    • Petch, L.A.1    Harris, J.2    Raymond, V.W.3    Blasband, A.J.4    Lee, D.C.5    Earp, H.S.6
  • 46
    • 0026509115 scopus 로고
    • The gene encoding hypoxanthine-guanine phosphoribosyltransferase as target for mutational analysis: PCR cloning and sequencing of the cDNA from the rat
    • Jansen JG, Vneling H, van Zeeland AA, Mohn GR. The gene encoding hypoxanthine-guanine phosphoribosyltransferase as target for mutational analysis: PCR cloning and sequencing of the cDNA from the rat. Mutat Res 266 105-116, 1992.
    • (1992) Mutat Res , vol.266 , pp. 105-116
    • Jansen, J.G.1    Vneling, H.2    Van Zeeland, A.A.3    Mohn, G.R.4
  • 47
    • 17544394651 scopus 로고
    • Semi-dry electrophoretic transfer of RNA to membranes
    • Lane KB, Zoia O, Davidson JM Semi-dry electrophoretic transfer of RNA to membranes BioTechniques 12.340-342, 1992.
    • (1992) BioTechniques , vol.12 , pp. 340-342
    • Lane, K.B.1    Zoia, O.2    Davidson, J.M.3
  • 48
    • 0026675229 scopus 로고
    • Synthesis of cRNA probes from PCR-generated DNA
    • Logel J, Dill D, Leonard S Synthesis of cRNA probes from PCR-generated DNA. BioTechniques 13 604-610, 1992.
    • (1992) BioTechniques , vol.13 , pp. 604-610
    • Logel, J.1    Dill, D.2    Leonard, S.3
  • 49
    • 0019320348 scopus 로고
    • Autocrine secretion and malignant transformation of cells
    • Sporn MB, Todaro GJ. Autocrine secretion and malignant transformation of cells. N Engl J Med 303-878-880, 1980
    • (1980) N Engl J Med , vol.303 , pp. 878-880
    • Sporn, M.B.1    Todaro, G.J.2
  • 50
    • 0027931473 scopus 로고
    • Transgenic mice provide genetic evidence that transforming growth factor α promotes skin tumorigenesis via H-ras-dependent and H-ras-independent pathways
    • Jhappan C, Takayama H, Dickson RB, Merlino G Transgenic mice provide genetic evidence that transforming growth factor α promotes skin tumorigenesis via H-ras-dependent and H-ras-independent pathways. Cell Growth Differ 5.385-394, 1994.
    • (1994) Cell Growth Differ , vol.5 , pp. 385-394
    • Jhappan, C.1    Takayama, H.2    Dickson, R.B.3    Merlino, G.4
  • 51
    • 0028332305 scopus 로고
    • Epidermal expression of transforming growth factor-α in transgemc mice: Induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression
    • Wang X-J, Greenhalgh DA, Eckhardt JN, Rothnagel JA, Roop DR Epidermal expression of transforming growth factor-α in transgemc mice: Induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression Mol Carcinog 10 15-22, 1994
    • (1994) Mol Carcinog , vol.10 , pp. 15-22
    • Wang, X.-J.1    Greenhalgh, D.A.2    Eckhardt, J.N.3    Rothnagel, J.A.4    Roop, D.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.