TCR αβ gene usage for myelin basic protein recognition in healthy monozygous twins

Journal of Immunology

Volumn 156, Issue 10, 1996, Pages 3747-3754

  Shanmugam, Ananth ^a   Copie Bergman, Christiane ^a   Falissard, Bruno ^a   Delrieu, Olivier ^a   Jais, Jean Philippe ^a   Rebibo, Danielle ^a   Bach, Jean François ^a   Tournier Lasserve, Elisabeth ^a,b  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MYELIN BASIC PROTEIN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ALLERGIC ENCEPHALITIS; ANTIGEN RECOGNITION; ARTICLE; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MONOZYGOTIC TWINS; MULTIGENE FAMILY; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; T LYMPHOCYTE;

AMINO ACID SEQUENCE; BASE SEQUENCE; CELL LINE; EPITOPES; HUMANS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; MYELIN BASIC PROTEINS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTES; TWINS, MONOZYGOTIC;

EID: 0029917619     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Zamvil, S. S., and L. Steinman 1990 The T lymphocyte in experimental allergic encephalomyelitis. Annu Rev. Immunol 8:579
2. Wekerle, H , K. Kojima, J. Lannes-Vieira, H. Lassmann, and C. Linington. 1994. Animal models. Ann Neurol. 36:S47.
3. Joshi, N., K. Usuku, and S. L. Hauser. 1993. The T cell response to myelin basic protein in familial multiple sclerosis: diversity of fine specificity, restricting elements and T cell receptor usage. Ann. Neurol. 34:385.
4. Ota, K , M. Matsui, E. L. Milford, G. A. Mackin, H. L. Weiner, and D. A. Hafler. 1990. T-cell recognition of an immunodominant myelin basic protein epitope in MS. Nature 346:183.
5. Pette, M , K Fujita, D Wilkinson, D. M. Altmann, J Trowsdale, G. Giegerich, A. Hinkannen, J T. Epplen, L. Kappos, and H Wekerle. 1990. Myelin autoreactivity in multiple sclerosis: recognition of myelin basic protein in the context of HLA-DR2 products by T lymphocytes of multiple sclerosis patients and healthy donors Proc. Natl. Acad. Sci USA 87:7968
6. Martin, R., R. Voskuhl, M. Flerlage, D E. McFarlin, and H. F. McFarland. 1993. Myelin basic protein specific T cell responses in identical twins discordant or concordant for multiple sclerosis. Ann. Neurol. 34:524.
7. Liblau, R., E. Tournier-Lasserve, J. Maciazek, G. Dumas, O. Siffert, G. Hashim, and M A. Bach. 1991. T cell response to myelin basic protein epitopes in multiple sclerosis patients and healthy subjects. Eur. J. Immunol. 21:1391.
8. Meinl, E., F. Weber, K. Drexler, C. Morelle, M. Ott, G. S. Direskeneli, N. Goebels, B. Ertl, G. Jechart, G. Giegerich, S. Schonbeck, W. Bannwarth, H. Wekerle, and R. Hohfeld. 1993. Myelin basic protein-specific T lymphocyte repertoire in multiple sclerosis. J. Clin Invest. 92:2633
9. Salvetti, M., G. Ristori, M. D'Amato, C. Buttinelli, M Falcone, C. Fieschi, H. Wekerle, and C. Pozzilli. 1993. Predominant and stable T cell responses to regions of myelin basic protein can be detected in individual patients with multiple sclerosis. Eur. J. Immunol. 23:1232.
10. Valli, A., A. Sette, L. Kappos, C. Oseroff, J Sidney, G. Miescher, M. Hochberger, E D. Albert, and A. Adorini. 1993. Binding of myelin basic protein peptides to human histocompatibility leukocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patients. J. Clin. Invest. 91:616.
11. Shanmugam, A., C. Copie-Bergmann, G. Hashim, G. Rebibo, J P. Jais, J F. Bach, M. A. Bach, and E Tournier-Lasserve. 1994. Healthy monozygous twins do not recognize identical T cell epitopes on the myelin basic protein autoantigen Eur J. Immunol. 24:2299.
12. Ben-Nun, A., R. S. Liblau, L. Cohen, E. Tournier-Lasserve, A. Rozenweig, Z Jingwu, J. C M. Raus, and M. A Bach. 1991. Restricted T-cell receptor Vβ gene usage by myelin basic protein-specific T-cell clones in multiple sclerosis: predominant genes vary in individuals. Proc. Natl. Acad. Sci. USA 88:2466.
13. Wucherpfennig, K W., K. Ota, N. Endo, J. G. Seidman, A. Rosenweig, H. L. Weiner, and D A. Hafler. 1990. Shared human T cell receptor Vβ usage to immunodominant regions of myelin basic protein. Science 24:1016.
14. Geigerich, G., M. Pette, E Meinl, J. T. Epplen, H. Wekerle, and A. Hinkannen. 1992. Diversity of T cell receptor α and β chain genes expressed by human T cells specific for similar myelin basic protein peptide/major histocompatibility complexes. Eur. J. Immunol. 122:753.
15. + cytotoxic T cell response for the immunodominant myelin basic protein peptide 87-106. J Immunol. 148:1359.
16. Kotzin, B. L., S. Karuturi, Y. K Chou, J. Lafferty, J. M. Forrester, M. Better, G. E. Nedwin, H., Offner, and A. A. Vandenbark. 1991. Preferential T-cell receptor β-chain variable gene use in myelin basic protein-reactive T-cell clones from patients with multiple sclerosis Proc. Natl. Acad. Sci. USA 88:9161.
17. Utz, U., W. E. Biddison, H. F. McFarland, D. E. McFarlin, M. Flerlage, and R. Martin 1993. Skewed T cell repertoire in genetically identical twins correlates with multiple sclerosis. Nature 364:243.
18. Martin, R., M. D. Howell, D. Jaraquemada, M. Flerlage, J. Richert, S. Brostoff, E O Long, D. E. McFarlin, and H. F McFarland. 1991. A myelin basic protein peptide is recognized by cytotoxic T cells in the context of four HLA-DR types associated with multiple sclerosis. J. Exp. Med. 173:19.
19. Genevée, C., A. Diu, J. Nierat, A Caignard, P. Y. Dietrich, L. Ferradiru, S. Roman-Roman, F. Triebel, and T Hercend 1992. An experimentally validated panel of subfamily-specific oligonucleotide primers (Vα1-w29/Vβ1-24) for the study of human T cell receptor variable V gene segment usage by polymerase chain reaction Eur J Immunol. 22:1261.
20. Oksenberg, J. R., S. Stuart, B. A. Begovich, R. B. Bell, H. A. Erlich, L. Steinman, and C. C. A. Bernard. 1990. Limited heterogeneity of rearranged T-cell receptor in brain of multiple sclerosis patients. Nature 345:344.
21. Eferon, B. 1979. Bootstrap method an overlook at the Jacknife. Ann. Stat 7:1.
22. Triebel, F., R. Breathnach, M. Graziani, T. Hercend, and P. Debré. 1988. Evidence for expression of two distinct T cell receptor β-chain transcripts in a human diptheria toxoid-specific T cell clone. J. Immunol. 140:300.
23. Shanmugam, A., C. Copie-Bergman, S. Caillat, I. F. Bach, and E. Tournier-Lasserve. 1995. In-vivo clonal expansion of T lymphocytes specific for a new immunodominant myelin basic protein epitope in healthy individuals. J. Neuroimmunol 59:165.
24. Wucherpfennig, K., H L. Weiner, and D. A. Hafler. 1991. T cell recognition of myelin basic protein Immunol. Today 12:277.
25. Cox, D. R., and D. V. Hinkley. 1974. Theoretical Statistics. Chapman & Hall, New York
26. Moss, P. A. H., W. M. C. Rosenberg, E. Zintaras, and J. I Bell. 1993. Characterization of the human T cell receptor α-chain repertoire and demonstration of a genetic influence on Vα usage. Eur J. Immunol. 23:1153.
27. Rosenberg, W. M. C., P. A. H. Moss, and J. I. Bell. 1992. Variation in human T cell receptor Vβ and Jβ repertoire: analysis using anchor polymerase chain reaction. Eur J. Immunol. 22:541.
28. Kohsaka, H., A Taniguchi, P Chen, W E. R. Ollier, and D. A. Carson. 1993 The expressed T cell receptor V gene repertoire of rheumatoid arthritis monozygous twins: rapid analysis by anchored polymerase chain reaction and enzyme-linked immunosorbent assay. Eur. J Immunol. 23:1895.
29. Usuku, K N., Joshi, C J. Hatem, C. A Alper, D. A Schoenfeld, and S. L. Hauser. 1993. The human T cell receptor β-chain repertoire: longitudinal fluctuations and assessment in MHC matched populations. Immunogenetics 38:193.
30. Akolkar, P N., B. Gulwani-Akolkar, R. Pergolizzi, R. D. Bigler, and J Silver. 1993. Influence of HLA genes on T cell receptor V segment frequencies and expression levels in peripheral blood lymphocytes. J. Immunol. 150:2761.
31. Malhotra, U., R Spielman, and P. Concannon. 1992. Variability in T cell receptor Vβ gene usage in human peripheral blood lymphocytes. J. Immunol. 149 1802.
32. Roman-Roman, S., L. Ferradini, J. Azocar, C. Genevée, F. Triebel, and T. Hercend. 1991. Studies on the human T cell receptor α/β variable region genes. I. Identification of 7 additional Vα subfamilies and Jα gene segments Eur. J. Immunol. 21:927.
33. Wilson, R. K , E. Lai, P. Concannon, R. K. Barth, and L. E. Hood. 1988 Structure organisation and polymorphism of murine and human T-cell receptor alpha and beta chain genes. Immunol Rev. 101:149
34. Koop, F. B., L. Rowen, K. Wang, C. L. Kuo, D. Seto, J. A. Lenstra, S Howard, W Shan, P. Deshpande, and L. Hood. 1994. The human T-cell receptor TCRAC/ TCRDC (Cα/Cδ) region: organisation, sequence and evolution of 97 6 kb of DNA Genomics 19:478.
35. Wei, S , P. Charmley, M. A. Robinson, and P. Concannon. 1994. The extent of the human germline T-cell receptor V beta segment repertoire. Immunogenetics 40:27.
36. Ferradini, L, S Roman-Roman. J. Azocar, H. Michalaki, F. Triebel, and T. Hercend 1991. Studies on the human T cell receptor α/β variable region genes. II. Identification of four additional Vβ subfamilies. Eur. J. Immunol 21: 935.
37. Toyonaga, B., and T. W. Mak. 1987. Genes of the T-cell antigen receptor in normal and malignant cells. Annu. Rev. Immunol 5:585.