Specific accumulation of lipoprotein(a) in balloon-injured rabbit aorta in vivo

Circulation Research

Volumn 78, Issue 4, 1996, Pages 615-626

  Nielsen, Lars B ^a   Stender, Steen ^a   Kjeldsen, Knud ^a   Nordestgaard, Børge G ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

angioplasty; atherosclerosis; lipoprotein(a); low density lipoprotein; restenosis

Indexed keywords

CHOLESTEROL; LIPOPROTEIN; LIPOPROTEIN A; LOW DENSITY LIPOPROTEIN;

ANGIOPLASTY; ANIMAL MODEL; ANIMAL TISSUE; AORTA INJURY; ARTICLE; CONTROLLED STUDY; IMMUNOELECTROPHORESIS; MALE; NONHUMAN; PERMEABILITY; PRIORITY JOURNAL; RABBIT; TURBIDIMETRY;

EID: 0029917512     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.78.4.615     Document Type: Article

References (47)

1. Utermann G. The mysteries of lipoprotein(a). Science. 1989;246: 904-910.
2. Scanu AM, Fless GM. Lipoprotein(a): heterogeneity and biological relevance. J Clin Invest. 1990;85:1709-1715.
3. Hoff HF, Beck GJ, Skibinski CI, Jürgens G, O'Neil J, Kramer J, Lytle B. Serum Lp(a) level as a predictor of vein graft stenosis after coronary artery bypass surgery in patients. Circulation. 1988;77: 1238-1244.
4. Hearn JA, Donohue BC, Ba'albaki H, Douglas JS, King SB III, Lembo NJ, Roubin GS, Sgoutas DS. Usefulness of serum lipoprotein(a) as a predictor of restenosis after percutaneous transluminal coronary angioplasty. Am J Cardiol. 1992;69:736-739.
5. Austin GE. Lipids and vascular restenosis. Circulation. 1992;85: 1613-1615.
6. Lawn RM, Wade DP, Hammer RE, Chiesa G, Verstuyft JG, Rubin EM. Atherogenesis in transgenic mice expressing human apolipoprotein(a). Nature. 1992;360:670-672.
7. Eaton DL, Fless GM, Kohr WJ, McLean JW, Xu Q, Miller CG, Lawn RM, Scanu AM. Partial amino acid sequence of apolipoprotein(a) shows that it is homologous to plasminogen. Proc Natl Acad Sci USA. 1987;84:3224-3228.
8. Zioncheck TF, Powell LM, Rice GC, Eaton DL, Lawn RM. Interaction of recombinant apolipoprotein(a) and lipoprotein(a) with macrophages. J Clin Invest. 1991;87:767-771.
9. Grainger DJ, Kirschenlohr HL, Metcalfe JC, Wiessberg PL, Wade DP, Lawn RM. Proliferation of human smooth muscle cells promoted by lipoprotein(a). Science. 1993;260:1655-1658.
10. Howard GC, Pizzo SV. Lipoprotein(a) and its role in atherothrombotic disease. Lab Invest. 1993;69:373-386.
11. Bihari-Varga M, Gruber E, Rotheneder M, Zechner R, Kostner GM. Interaction of lipoprotein Lp(a) and low-density lipoprotein with glycosaminoglycans from human aorta. Arteriosclerosis. 1988;8: 851-857.
12. Molinari EA, Pichler PF, Grillhofer H, Kostner GM. Immunoturbidimetric determination of lipoprotein(a): improvement in the measurement of turbid and triglyceride-rich samples. Clin Chim Acta. 1995;235:59-65.
13. Utermann G, Menzel HJ, Kraft HG, Kemmler HG, Seitz C. Lp(a) glycoprotein phenotypes: inheritance and relation to Lp(a) lipoprotein concentrations in plasma. J Clin Invest. 1987;80:458-465.
14. Nielsen LB, Slender S, Kjeldsen K, Nordestgaard BG. Effect of angiotensin II and enalapril on transfer of low-density lipoprotein into aortic intima in rabbits. Circ Res. 1994;75:63-69.
15. Zilversmit DB, Shea TM. Quantitation of apoB-48 and apoB-100 by gel scanning or radioiodination. J Lipid Res. 1989;30:1639-1646.
16. McFarlane AS. Efficient trace-labelling of proteins with iodine. Nature. 1958;182:53.
17. Bilheimer DW, Eisenberg S, Levy RI. The metabolism of very low density lipoprotein proteins, I: preliminary in vitro and in vivo observations. Biochim Biophys Acta. 1972;260:212-221.
18. Chapman MJ. Comparative analysis of mammalian plasma lipoproteins. Methods Enzymol. 1986;128:70-143(Table V).
19. Nielsen LB, Nordestgaard BG, Stender S, Kjeldsen K. Aortic permeability to LDL as a predictor of aortic cholesterol accumulation in cholesterol-fed rabbits. Arterioscler Thromb. 1992;12:1402-1409.
20. Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem. 1957;226:497-509.
21. Ness AT, Pastewka JV, Peakock AC. Evaluation of a recently reported stable Liebermann-Burchard reagent and its use for the direct determination of serum total cholesterol. Clin Chim Acta. 1964;10:229-237.
22. Nordestgaard BG, Wootton R, Lewis B. Selective retention of VLDL, IDL, and LDL in the arterial intima of genetically hyperlipidemic rabbits in vivo: molecular size as a determinant of fractional loss from the intima-inner media. Arterioscler Thromb Vasc Biol. 1995;15:534-542.
23. Ghosh S, Armstrong M, Megan MB, Cheng FH. Arterial uptake indices of low density lipoproteins after fatty streak formation in cynomolgus monkeys. Cardiovasc Res. 1987;21:14-20.
24. Schwenke DC, Zilversmit DB. The arterial barrier to lipoprotein influx in the hypercholesterolemic rabbit, 1: studies during the first two days after mild aortic injury. Atherosclerosis. 1989;77:91-103.
25. Bickel PJ, Doksum KA. In: Lehman EL, ed. Mathematical Statistics: Basic Ideas and Selected Topics. Oakland, Calif: Holden-Day Inc; 1977:283.
26. Jennrich RI, Schluchter MD. Unbalanced repeated-measures models with structured covariance matrices. Biometrics. 1986;42: 805-820.
27. Roberts AB, Lees AM, Strauss HW, Fallon JT, Taveras J, Kopiwoda S. Selective accumulation of low density lipoproteins in damaged arterial wall. J Lipid Res. 1983;24:1160-1167.
28. Stemerman MB, Spaet TH, Pitlick F, Cintron J, Lejnieks I, Tiell ML. Intimal healing: the pattern of reendothelialization and intimal thickening. Am J Pathol. 1977;87:125-142.
29. Schwenke DC, Zilversmit DB. Enhanced accumulation and turnover of esterified cholesterol in injured rabbit aorta. Arteriosclerosis. 1987;7:367-377.
30. Schwenke DC, Carew TE. Initiation of atherosclerotic lesions in cholesterol-fed rabbits, II: selective retention of LDL vs. selective increases in LDL permeability in susceptible sites of arteries. Arteriosclerosis. 1989;9:908-918.
31. Schwenke DC, Zilversmit DB. The arterial barrier to lipoprotein influx in the hypercholesterolemic rabbit, 2: long-term studies in deendothelialized and reendothelialized aortas. Atherosclerosis. 1989;77:105-115.
32. Schwenke DC, Carew TE. Quantification in vivo of increased LDL content and rate of LDL degradation in normal rabbit aorta occurring at sites susceptible to early atherosclerotic lesions. Circ Res. 1988;62:699-710.
33. Wagner JD, St Clair RW, Schwenke DC, Shively CA, Adams MR, Clarkson TB. Regional differences in arterial low density lipoprotein metabolism in surgically postmenopausal cynomolgus monkeys: effects of estrogen and progesterone replacement therapy. Arterioscler Thromb. 1992;12:717-726.
34. Kreuzer J, Lloyd MB, Bok D, Fless GM, Scanu AM, Lusis AJ, Haberland ME. Lipoprotein(a) displays increased accumulation compared with low-density lipoprotein in the murine arterial wall. Chem Phys Lipids. 1994;67/68:175-190.
35. Knight BL, Perombelon YFN, Soutar AK, Wade DP, Seed M. Catabolism of lipoprotein(a) in familial hypercholesterolemic subjects. Atherosclerosis. 1991;87:227-237.
36. Rader DJ, Mann WA, Cain W, Kraft HG, Usher D, Zech LA, Hoek JB, Davignon J, Lupien P, Grossmann M, Wilson JM, Brewer HBJ. The low density lipoprotein receptor is not required for normal catabolism of Lp(a) in humans. J Clin Invest. 1995;95: 1403-1408.
37. Stender S, Zilversmit DB. Transfer of plasma lipoprotein components and of plasma proteins into aortas of cholesterol-fed rabbits: molecular size as a determinant of plasma lipoprotein influx. Arteriosclerosis. 1981;1:38-49.
38. Gordon JL, Pearson JD. Responses of endothelial cells to injury. In: Nossel HL, Vogel HJ, eds. Pathobiology of the Endothelial Cell. London, UK: Academic Press Inc; 1982:433-452.
39. Helin P, Lorenzen I, Garbarsch C, Matthiessen ME. Repair in arterial tissue: morphological and biochemical changes in rabbit aorta after a single dilatation injury. Circ Res. 1971;29:542-554.
40. Fless GM, Snyder ML. Polymorphic forms of Lp(a) with different structural and functional properties: cold-induced self-association and binding to fibrin and lysine-sepharose. Chem Phys Lipids. 1994; 67/68:69-79.
41. Smith EB, Cochran S. Factors influencing the accumulation in fibrous plaques of lipid derived from low density lipoprotein, II: preferential immobilization of lipoprotein(a) [Lp(a)]. Atherosclerosis. 1990;84:173-181.
42. Carew TE, Pittman RC, Marchand ER, Steinberg D. Measurement in vivo of irreversible degradation of low-density lipoprotein in the rabbit aorta: predominance of intimal degradation. Arteriosclerosis. 1984;4:214-224.
43. Bondjers G, Glukhova M, Hansson GK, Postnov YV, Reidy MA, Schwartz SM. Hypertension and atherosclerosis: cause and effect, or two effects with one unknown cause? Circulation. 1991;84(suppl VI):VI-2-VI-16.
44. Reidy MA. Biology of disease: a reassessment of endothelial injury and arterial lesion formation. Lab Invest. 1985;53:513-520.
45. Stary HC, Chandler AB, Glagov S, Guyton JR, Insull W Jr, Rosenfeld ME, Schaffer SA, Schwartz CJ, Wagner WD, Wissler RW. A definition of initial, fatty streak, and intermediate lesions of atherosclerosis: a report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Arterioscler Thromb. 1994;14:840-856.
46. Williams KJ, Tabas I. The response-to-retention hypothesis of early atherosclerosis. Arterioscler Thromb Vasc Biol. 1995;15:551-561.
47. Jackson CL, Raines EW, Ross R, Reidy MA. Role of endogenous platelet-derived growth factor in arterial smooth muscle cell migration after balloon catheter injury. Arterioscler Thromb. 1993; 13:1218-1226.