Role of Intimal Hyperplasia and Arterial Remodeling after Balloon Angioplasty: An Experimental Study in the Atherosclerotic Rabbit Model

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 16, Issue 3, 1996, Pages 479-487

  Guzman, Luis A ^a   Mick, Mathew J ^a   Arnold, Anita M ^a   Forudi, Farhad ^a   Whitlow, Patrick L ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Arterial remodeling; Atherosclerotic rabbit model; Balloon angioplasty; Restenosis

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY DIAMETER; ARTERY INJURY; ARTERY INTIMA PROLIFERATION; ARTERY OCCLUSION; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; FEMORAL ARTERY; NONHUMAN; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PRIORITY JOURNAL; RABBIT;

EID: 0029917275     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.16.3.479     Document Type: Article

References (42)

1. Califf RM, Ohman EM, Frid DJ, Fortin DF, Mark DB. Hlatky MA, Herndon JE, Bengtson JR. Restenosis: the clinical issue. In: Topol EJ, ed. Textbook of Interventional Cardiology. Philadelphia, Pa: WB Saunders Co; 1990:363-394.
2. Popma JJ, Califf RM, Topol EJ. Clinical trials of restenosis after coronary angioplasty. Circulation. 1991;84:1426-1436.
3. Kuntz R, Gibson C, Nobuyoshi M, Baim D. Generalized model of restenosis after conventional balloon angioplasty, stenting and directional atherectomy. J Am Cod Cardiol. 1993;21:15-25.
4. Kuntz RE, Safian RD, Levine MJ, Reis GJ, Diver DJ, Baim DS. Novel approach to the analysis of restenosis after the use of three new coronary devices. J Am Coll Cardiol. 1992;19:1493-1499.
5. Beatt KJ, Serruys PW, Luijten HE, Rensing BJ, Suryapranata H, de Feyter P, van den Brand M, Laarman GJ, Roelandt J. Restenosis after coronary angioplasty: the paradox of increased lumen diameter and restenosis. J Am Coll Cardiol. 1992;19:258-266.
6. Schwartz RS, Huber KC, Murphy JG, Edwards WD, Camrud AR, Vlietstra RE, Holmes DR. Restenosis and the proportional neointimal response to coronary artery injury: results in a porcine model. J Am Coll Cardiol. 1992;19:267-274.
7. Nobuyoshi M, Kimura T, Ohishi H, Horiuchi H, Nosaka H, Hamasaki N, Yokoi H, Kim K. Restenosis after percutaneous transluminal coronary angioplasty: pathologic observations in 20 patients. J Am Coll Cardiol. 1991;17:433-439.
8. Ueda M, Becker AE, Tsukada T, Numano F, Fujimoto T. Fibro-cellular tissue response after percutaneous transluminal coronary angioplasty. Circulation. 1991;83:1327-1332.
9. Garratt KN, Holmes DR, Bell MR, Bresnahan JF, Kaufmann UP, Vlietstra RE, Edwards WD. Restenosis after directional coronary atherectomy: differences between primary atheromatous and restenotic lesions and influence of subintimal tissue resection. J Am Coll Cardiol. 1990;16:1665-1671.
10. Austin GE, Ratliff NB, Hollman J, Tabei S, Phillips DF. Intimal proliferation of smooth muscle as an explanation for recurrent coronary artery stenosis after percutaneous transluminal coronary angioplasty. J Am Coll Cardiol. 1985;6:369-375.
11. Waller BF, Pinkerton CA, Orr CM, Slack JD, Van Tassel JW, Peters T. Restenosis 1 to 24 months after clinically successful coronary balloon angioplasty: a necropsy study of 20 patients. J Am Coll Cardiol. 1991;17:58B-70B.
12. Isner JM. Vascular remodeling: Honey, I think I shrunk the artery. Circulation. 1994;89:2937-2941.
13. Mintz GS, Kovach JA, Pichard AD, Kent KM, Satler LF, Popma JJ, Painter JA, Morgan K, Leon MB. Geometric remodeling is the predominant mechanism of clinical restenosis after coronary angioplasty. J Am Coll Cardiol. 1994:138A. Abstract.
14. Mintz GS, Matar FA, Kent KM, Pichard AD, Satler LF, Harvey M, Ditrano JC, Prunka N, Popma JP, Leon MB. Chronic compensatory arterial dilatation following coronary angioplasty: an intravscular ultrasound study. J Am Coll Cardiol. 1994:139A. Abstract.
15. Fishman J, Ryan GB, Karnovsky MJ. Endothelial regeneration in the rat carotid artery and the significance of endothelial denudation in the pathogenesis of intimal thickening. Lab Invest. 1975;32:339-351.
16. Sarembock IJ, La Veau PJ, Sigal SL, Timms I, Sussman J, Haudenschild C, Ezekowitz MD. Influence of inflation pressure and balloon size on the development of intimal hyperplasia after balloon angioplasty. Circulation. 1989;80:1029-1040.
17. LeVeen RF, Wolf GL, Villanueva TG. New rabbit atherosclerosis model for the investigation of transluminal angioplasty. Invest Radiol. 1982;17:470-475.
18. Kritchevsky D, Tepper SA, Kim HK, Story JA, Vesselinovitch D, Wissler RW. Experimental atherosclerosis in rabbits fed cholesterol-free diets: comparison with peanut, corn, butter and coconut oils. Exp Mol Pathol. 1976;24:375-391.
19. Scoblionko DP, Brown BG, Mitten S, Caldwell JH, Kennedy JW, Bolson EL, Dodge HT. A new digital electronic caliper for measurement of coronary arterial stenosis: comparison with visual estimates and computer-assisted measurements. Am J Cardiol. 1984;53:689-693.
20. Califf RM, Fortin DF, Frid DJ, Harlan WR, Ohman EM, Bengtson JR, Nelson CL, Tcheng JE, Mark DB, Stack RS. Restenosis after coronary angioplasty: an overview. J Am Coll Cardiol. 1991;17:2B-13B.
21. Holmes DR, Vlietstra RE, Smith HC, Vetrovec GW, Kent KM, Cowley MJ, Faxon DP, Gruentzig AR, Kelsey SF, Detre KM, van Raden MJ, Mock MB. Restenosis after percutaneous transluminal coronary angioplasty (PTCA): a report from the PTCA registry of the National Heart, Lung, and Blood Institute. Am J Cardiol. 1984;53:77C-81C.
22. Steele PM, Chesebro JH, Stanson AW, Holmes DR Jr, Dewanjee MK, Badimon L, Fuster V. Balloon angioplasty: natural history of the pathophysiological response to injury in a pig model. Circ Res. 1985;57:105-112.
23. Fingerle J, Johnson R, Clowes A, Majesky MW, Reidy MA, Role of platelets in smooth muscle cell proliferation and migration after vascular injury in rat carotid artery. Proc Natl Acad Sci U S A. 1989;86:8412-8416.
24. Sarembock IJ, Gertz D, Gimple LW, Owen RM, Powers ER, Roberts WC. Effectiveness of recombinant desulphatohirudin in reducing restenosis after balloon angioplasty of atherosclerotic femoral arteries in rabbits. Circulation. 1991;84:232-243.
25. Villa A, Guzman L, Chen W, Golomb G, Levy R, Topol E. Local delivery of dexamethasone for prevention of neointimal proliferation in a rat model of balloon angioplasty. J Clin Invest. 1994;93:1243-1249.
26. Ferns G, Raines E, Sprugel K, Motani A, Reidy M, Ross R. Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF. Science. 1991;253:1129-1132.
27. Weintraub WS, Boccuzzi SJ, Klein JL, Kosinski AS, King SB, Ivanhoe R, Cedarholm JC, Stillabower ME, Talley JD, DeMaio SJ, O'Neill NW, Frazier JE, Cohen-Bernstein CL, Robbins DC, Brown CL, Alexander RW. Lack of effect of lovastatin on restenosis after coronary angioplasty: lovastatin restenosis trial study group. N Engl J Med. 1994;331:1331-1337.
28. Serruys PW, Rutsch W, Heyndrickx GR, Danchin N, Mast EG, Wijns W, Rensing BJ, Vos J, Stibbe J, for the Coronary Artery Restenosis Prevention on Repeated Thromboxane-Antagonism Study Group (CARPORT). Prevention of restenosis after percutaneous transluminal coronary angioplasty with thromboxane A2-receptor blockade - a randomized, double-blind, placebo-controlled trial. Circulation. 1991;84:1568-1580.
29. The Multicenter European Research Trial with Cilazapril After Angioplasty to Prevent Transluminal Coronary Obstruction and Restenosis (MERCATOR) Study Group. Does the new angiotensin converting enzyme inhibitor Cilazapril prevent restenosis after percutaneous transluminal coronary angioplasty? Results of the MERCATOR Study. Circulation. 1992;86:100-110.
30. Kent KM, Williams DO, Cassagneau B, Broderick T, Chapekis A, Simpfendorfer C, Cote G, Bates E, Tauscher G, Kuntz RE, Popma JJ, Foegh M. Double blind, controlled trial of the effect of angio-peptin on coronary restenosis following balloon angioplasty. Circulation. 1993;88(suppl I):I-506. Abstract.
31. Thornton MA, Gruentzig AR, Hollman J, King SB III, Douglas JS. Coumadin and aspirin in prevention of recurrence after transluminal coronary angioplasty: a randomized study. Circulation. 1984;69:721-727.
32. Whitworth HB, Roubin GS, Hollman J, Meier B, Leimgruber PP, Douglas JS, King SB, Gruentzig AR, Effect of nifedipine on recurrent stenosis after percutaneous transluminal coronary angioplasty. J Am Coll Cardiol. 1986;8:1271-1276.
33. O'Keefe JH, McCallister BD, Bateman TM, Kuhnlein DL, Ligon RW, Hartzler GO. Ineffectiveness of colchicine for the prevention of restenosis after coronary angioplasty. J Am Coll Cardiol. 1992;19:1597-1600.
34. Post MJ, Borst C, Kuntz RE. The relative importance of arterial remodeling compared with intimal hyperplasia in lumen renarrowing after balloon angioplasty: a study in the normal rabbit and the hypercholesterolemic Yucatan Micropig. Circulation. 1994;89:2816-2821.
35. Kakuta T, Currier JW, Haudenschild CC, Ryan TJ, Faxon DP. Differences in compensatory vessel enlargement, not intimal formation, account for restenosis after angioplasty in the hypercholesterolemic rabbit model. Circulation. 1994;89:2809-2815.
36. Gertz S, Gimple L, Benai S, Ragosta M, Powers E, Roberts W, Perez L, Sarembock I. Geometric remodeling is not a principal pathogenetic process in restenosis after balloon angioplasty: evidence from correlative angiographic-histomorphometric studies of atherosclerotic arteries in rabbits. Circulation. 1995;90:3001-3008.
37. Lafont A, Guzman L, Whitlow P, Goormastic M, Cornhill J, Chisolm G. Restenosis after experimental angioplasty: intimal, medial, and adventitial changes associated with constrictive remodeling. Circ Res. 1995;76:996-1002.
38. Glagov S, Weisenberg E, Zarins CK, Stankunavicius R, Kolettis GJ. Compensatory enlargement of human atherosclerotic coronary arteries. N Engl J Med. 1987;316:1371-1375.
39. Glagov S, Zarins CK, Masawa N, Xu CP, Bassiouny H, Giddens DP. Mechanical functional role of non-atherosclerotic intimal thickening. Front Med Biol Eng. 1993;5:37-43.
40. Zarins CK, Weisenberg E, Kolletis G, Stankunavicius R, Glagov S. Differential enlargement of artery segments in response to enlarging atherosclerotic plaque. J Vasc Surg. 1988;7:386-394.
41. La Veau PJ, Sarembock IJ, Sigal SL, Yang TL, Ezekowitz MD. Vascular reactivity after balloon angioplasty in an atherosclerotic rabbit. Circulation. 1990;82:1790-1801.
42. Faxon DP, Weber VJ, Haudenschild C, Gottsman SB, MacGovern WA, Ryan TJ. Acute effects of transluminal angioplasty in three experimental models of atherosclerosis. Arteriosclerosis. 1982;2:125-133.