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Volumn 44, Issue 2, 1996, Pages 124-132

Induction of connexin43 and gap junctional communication in PC12 cells overexpressing the carboxy terminal region of amyloid precursor protein

Author keywords

A4 amyloid; Alzheimer's disease; connexin43; gap junctions; PC12 cells

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CONNEXIN 43; LUCIFER YELLOW;

EID: 0029917161     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19960415)44:2<124::AID-JNR4>3.0.CO;2-F     Document Type: Article
Times cited : (12)

References (42)
  • 2
    • 0027254716 scopus 로고
    • Gap junctions
    • Beyer EC (1993): Gap junctions. Int Rev Cytol 137:1-37.
    • (1993) Int Rev Cytol , vol.137 , pp. 1-37
    • Beyer, E.C.1
  • 3
    • 0023551497 scopus 로고
    • Connexin43: A protein from rat heart homologous to a gap junction protein from liver
    • Beyer EC, Paul DL, Goodenough DA (1987): Connexin43: a protein from rat heart homologous to a gap junction protein from liver. J Cell Biol 105:2621-2629.
    • (1987) J Cell Biol , vol.105 , pp. 2621-2629
    • Beyer, E.C.1    Paul, D.L.2    Goodenough, D.A.3
  • 7
    • 0026468207 scopus 로고
    • Expression of a carboxy-terminal region of the β-amyloid precursor protein in a heterogeneous culture of neuroblastoma cells: Evidence for altered processing and selective neurotoxicity
    • Fukuchi KI, Kamino K, Deeb SS, Furlong CE, Sundstrom JA, Smith AC, Martin CM (1992a): Expression of a carboxy-terminal region of the β-amyloid precursor protein in a heterogeneous culture of neuroblastoma cells: evidence for altered processing and selective neurotoxicity. Mol Brain Res 16:37-46.
    • (1992) Mol Brain Res , vol.16 , pp. 37-46
    • Fukuchi, K.I.1    Kamino, K.2    Deeb, S.S.3    Furlong, C.E.4    Sundstrom, J.A.5    Smith, A.C.6    Martin, C.M.7
  • 8
    • 0026542758 scopus 로고
    • Overexpression of amyloid precursor protein alters its normal processing and is associated with neurotoxicity
    • Fukuchi KI, Kamino K, Deeb SS, Smith AC, Dang T, Martin GM (1992b): Overexpression of amyloid precursor protein alters its normal processing and is associated with neurotoxicity. Biochem Biophys Res Commun 182:165-173.
    • (1992) Biochem Biophys Res Commun , vol.182 , pp. 165-173
    • Fukuchi, K.I.1    Kamino, K.2    Deeb, S.S.3    Smith, A.C.4    Dang, T.5    Martin, G.M.6
  • 10
    • 0027379266 scopus 로고
    • High-level expression and in vitro mutagenesis of a fibrillogenic 109-amino acid C-terminal fragment of Alzbeimer's disease amyloid precursor protein
    • Gardella JE, Gorgone GA, Candela L, Ghiso J, Castano EM, Frangione B, Gorevic PD (1993): High-level expression and in vitro mutagenesis of a fibrillogenic 109-amino acid C-terminal fragment of Alzbeimer's disease amyloid precursor protein. Biochem J 294:667-674.
    • (1993) Biochem J , vol.294 , pp. 667-674
    • Gardella, J.E.1    Gorgone, G.A.2    Candela, L.3    Ghiso, J.4    Castano, E.M.5    Frangione, B.6    Gorevic, P.D.7
  • 11
    • 0026539090 scopus 로고
    • Processing of the amyloid protein precursor to potentially amyloidogenic derivatives
    • Golde TE, Estus S, Younkin LH, Selkoe DJ, Younkin SG (1992): Processing of the amyloid protein precursor to potentially amyloidogenic derivatives. Science 255:728-730.
    • (1992) Science , vol.255 , pp. 728-730
    • Golde, T.E.1    Estus, S.2    Younkin, L.H.3    Selkoe, D.J.4    Younkin, S.G.5
  • 13
    • 0024165145 scopus 로고
    • Topology of the Mr 27,000 liver gap junction protein. Cytoplasmic localization of amino- And carboxyl termini and a hydrophobic domain which is protease-hypersensitive
    • Hertzberg EL, Disher RM, Tiller AA, Zhou Y, Cook RG (1988): Topology of the Mr 27,000 liver gap junction protein. Cytoplasmic localization of amino- and carboxyl termini and a hydrophobic domain which is protease-hypersensitive. J Biol Chem 263:19105-19111.
    • (1988) J Biol Chem , vol.263 , pp. 19105-19111
    • Hertzberg, E.L.1    Disher, R.M.2    Tiller, A.A.3    Zhou, Y.4    Cook, R.G.5
  • 14
    • 0028286566 scopus 로고
    • Phosphorylated forms of connexin43 predominate in rat brain: Demonstration by rapid inactivation of brain metabolism
    • Hossain MZ, Murphy LJ, Hertzberg EL, Nagy JI (1994): Phosphorylated forms of connexin43 predominate in rat brain: demonstration by rapid inactivation of brain metabolism. J Neurochem 62:2394-2403.
    • (1994) J Neurochem , vol.62 , pp. 2394-2403
    • Hossain, M.Z.1    Murphy, L.J.2    Hertzberg, E.L.3    Nagy, J.I.4
  • 15
    • 0023872043 scopus 로고
    • Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity
    • Kitaguchi N, Takahashi Y, Tokushima Y, Shiojiri S, Ito H (1988): Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity. Nature 331:531-534.
    • (1988) Nature , vol.331 , pp. 531-534
    • Kitaguchi, N.1    Takahashi, Y.2    Tokushima, Y.3    Shiojiri, S.4    Ito, H.5
  • 16
    • 0028225403 scopus 로고
    • An in vitro model for the effects of estrogen on neurons employing estrogen receptor-transfected PC12 cells
    • Lustig RH, Hua P, Wyu W, Ahmad FJ, Baas PW (1994): An in vitro model for the effects of estrogen on neurons employing estrogen receptor-transfected PC12 cells. J Neurosci 14:3945-3957.
    • (1994) J Neurosci , vol.14 , pp. 3945-3957
    • Lustig, R.H.1    Hua, P.2    Wyu, W.3    Ahmad, F.J.4    Baas, P.W.5
  • 17
    • 0027067949 scopus 로고
    • Cell surface extensions associated with overexpression of Alzheimer β/A4 amyloid
    • Maestre GE, Tate B, Majocha RE, Marotta CA (1992): Cell surface extensions associated with overexpression of Alzheimer β/A4 amyloid. Brain Res 599:64-72.
    • (1992) Brain Res , vol.599 , pp. 64-72
    • Maestre, G.E.1    Tate, B.2    Majocha, R.E.3    Marotta, C.A.4
  • 18
    • 0027180334 scopus 로고
    • Membrane surface ruffling in cells that overexpress Alzheimer amyloid β/A4 C-terminal peptide
    • Maestre GE, Tate BA, Majocha RE, Marotta CA (1993): Membrane surface ruffling in cells that overexpress Alzheimer amyloid β/A4 C-terminal peptide. Brain Res 621:145-149.
    • (1993) Brain Res , vol.621 , pp. 145-149
    • Maestre, G.E.1    Tate, B.A.2    Majocha, R.E.3    Marotta, C.A.4
  • 20
    • 0026459302 scopus 로고
    • Development of a monoclonal antibody specific for β/A4 amyloid in Alzheimer's disease brain for application to in vivo imaging of amyloid angiopathy
    • Majocha RE, Reno JM, Van Haight C, Lyle LR, Freidland RP, Marotta CA (1992a): Development of a monoclonal antibody specific for β/A4 amyloid in Alzheimer's disease brain for application to in vivo imaging of amyloid angiopathy. J Nucl Med 33:2184-2189.
    • (1992) J Nucl Med , vol.33 , pp. 2184-2189
    • Majocha, R.E.1    Reno, J.M.2    Van Haight, C.3    Lyle, L.R.4    Freidland, R.P.5    Marotta, C.A.6
  • 21
    • 0027318115 scopus 로고
    • PC12 cells release stimulatory factors after transfection with β/A4 C-terminal DNA of the Alzheimer amyloid precursor protein
    • Majocha RE, Tate B, Marotta CA (1992b): PC12 cells release stimulatory factors after transfection with β/A4 C-terminal DNA of the Alzheimer amyloid precursor protein. Cell Mol Neurobiol 18:99-113.
    • (1992) Cell Mol Neurobiol , vol.18 , pp. 99-113
    • Majocha, R.E.1    Tate, B.2    Marotta, C.A.3
  • 22
    • 0024574962 scopus 로고
    • Overexpression of amyloid precursor protein A4 (β-amyloid) immunoreactivity in genetically transformed cells. Implications for a cellular model of Alzheimer amyloidosis
    • Marotta CA, Chou WG, Majocha RE, Watkins R, Zain SB (1989): Overexpression of amyloid precursor protein A4 (β-amyloid) immunoreactivity in genetically transformed cells. Implications for a cellular model of Alzheimer amyloidosis. Proc Natl Acad Sci USA 86:337-341.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 337-341
    • Marotta, C.A.1    Chou, W.G.2    Majocha, R.E.3    Watkins, R.4    Zain, S.B.5
  • 23
    • 0025133329 scopus 로고
    • Formation of amyloid like fibrils in cos cells overexpressing part of the Alzheimer amyloid protein precursor
    • Maruyama K, Terakado K, Usami M, Woshikawa K (1990): Formation of amyloid like fibrils in cos cells overexpressing part of the Alzheimer amyloid protein precursor. Nature 347:566-569.
    • (1990) Nature , vol.347 , pp. 566-569
    • Maruyama, K.1    Terakado, K.2    Usami, M.3    Woshikawa, K.4
  • 25
    • 0025789648 scopus 로고
    • Biochemical analysis of connexin43 intracellular transport, phosphorylation. and assembly into gap junctional plaques
    • Musil LS, Goodenough DA (1991): Biochemical analysis of connexin43 intracellular transport, phosphorylation. and assembly into gap junctional plaques. J Cell Biol 115:1357-1374.
    • (1991) J Cell Biol , vol.115 , pp. 1357-1374
    • Musil, L.S.1    Goodenough, D.A.2
  • 26
    • 0011161024 scopus 로고    scopus 로고
    • Gap junctions and connexins in the mammalian central nervous system
    • Hertzberg EL (ed): New York: JAI Press (in press)
    • Nagy JI, Dermietzel R (1996). Gap junctions and connexins in the mammalian central nervous system. In Hertzberg EL (ed): "Advances in Molecular and Cell Biology," vol. 18. New York: JAI Press (in press).
    • (1996) Advances in Molecular and Cell Biology , vol.18
    • Nagy, J.I.1    Dermietzel, R.2
  • 27
    • 9244241834 scopus 로고
    • Requirement of the hyaluronan receptor RHAMM in neurite extension and motility as demonstrated in primary neurons and neuronal cell lines
    • Nagy JI, Hacking J, Frankenstein UN, Turley EA (1995a): Requirement of the hyaluronan receptor RHAMM in neurite extension and motility as demonstrated in primary neurons and neuronal cell lines. J Neurosci 64:61-70.
    • (1995) J Neurosci , vol.64 , pp. 61-70
    • Nagy, J.I.1    Hacking, J.2    Frankenstein, U.N.3    Turley, E.A.4
  • 28
    • 9244262242 scopus 로고
    • Increased connexin43 and gap junctional communication correlates with altered phenotypic characteristics of cells overexpressing the hyaluronan receptor RHAMM
    • in press
    • Nagy JI, Hossain MZ, Lynn BD, Curpen GE, Turley EA (1995b): Increased connexin43 and gap junctional communication correlates with altered phenotypic characteristics of cells overexpressing the hyaluronan receptor RHAMM. Cell Growth Differ (in press).
    • (1995) Cell Growth Differ
    • Nagy, J.I.1    Hossain, M.Z.2    Lynn, B.D.3    Curpen, G.E.4    Turley, E.A.5
  • 29
    • 0022531305 scopus 로고
    • Molecular cloning of cDNA for rat liver gap junction protein
    • Paul DL (1986): Molecular cloning of cDNA for rat liver gap junction protein. J Cell Biol 103:123-134
    • (1986) J Cell Biol , vol.103 , pp. 123-134
    • Paul, D.L.1
  • 31
    • 0028085725 scopus 로고
    • Solubilization of full-length amyloid precursor proteins from PC12 cell membranes
    • Ripellino JA, Vassilacopoulou D, Robakis NK (1994): Solubilization of full-length amyloid precursor proteins from PC12 cell membranes. J Neurosci Res 39:211-218.
    • (1994) J Neurosci Res , vol.39 , pp. 211-218
    • Ripellino, J.A.1    Vassilacopoulou, D.2    Robakis, N.K.3
  • 32
    • 0027352474 scopus 로고
    • Multiplicity of controls in differentiated and undifferentiated cells and possible functional implications
    • Shenolikar S, Nairn AC (eds): New York: Raven Press
    • Saez JC, Berthoud VM, Moreno AP, Spray DC (1993): Multiplicity of controls in differentiated and undifferentiated cells and possible functional implications. In Shenolikar S, Nairn AC (eds): "Advances in Second Messenger and Phosphoprotein Research," vol. 27. New York: Raven Press, pp 163-198.
    • (1993) Advances in Second Messenger and Phosphoprotein Research , vol.27 , pp. 163-198
    • Saez, J.C.1    Berthoud, V.M.2    Moreno, A.P.3    Spray, D.C.4
  • 33
    • 0025373508 scopus 로고
    • Evidence that β-amyloid protein in Alzheimer's disease is not derived by normal processing
    • Sisodia SS, Koo EH, Beyreuther K, Unterbeck A, Price DL (1990): Evidence that β-amyloid protein in Alzheimer's disease is not derived by normal processing. Science 248:492-495.
    • (1990) Science , vol.248 , pp. 492-495
    • Sisodia, S.S.1    Koo, E.H.2    Beyreuther, K.3    Unterbeck, A.4    Price, D.L.5
  • 34
    • 0023850791 scopus 로고
    • Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease
    • Tanzi RE, McClatchey AI, Lamperti ED, Villa-Komaroff L, Gusella JF, Neve RL (1988): Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease. Nature 331:528-530.
    • (1988) Nature , vol.331 , pp. 528-530
    • Tanzi, R.E.1    McClatchey, A.I.2    Lamperti, E.D.3    Villa-Komaroff, L.4    Gusella, J.F.5    Neve, R.L.6
  • 36
    • 0024566344 scopus 로고
    • Comparative characterization of the 21-kD and 26-kD gap junction proteins in murine liver and cultured hepatocytes
    • Traub O, Look J, Dermietzel R, Brummer F, Hulser D, Willecke K (1989): Comparative characterization of the 21-kD and 26-kD gap junction proteins in murine liver and cultured hepatocytes. J Cell Biol 108:1039-1051.
    • (1989) J Cell Biol , vol.108 , pp. 1039-1051
    • Traub, O.1    Look, J.2    Dermietzel, R.3    Brummer, F.4    Hulser, D.5    Willecke, K.6
  • 37
    • 0028501218 scopus 로고
    • Astrocyte and microglial motility in culture is functionally dependent on the hyaluronic acid receptor RHAMM
    • Turley EA, Hossain MZ, Serokan T, Jordan LM, Nagy JI (1994): Astrocyte and microglial motility in culture is functionally dependent on the hyaluronic acid receptor RHAMM. Glia 12:68-80.
    • (1994) Glia , vol.12 , pp. 68-80
    • Turley, E.A.1    Hossain, M.Z.2    Serokan, T.3    Jordan, L.M.4    Nagy, J.I.5
  • 38
    • 0021627104 scopus 로고
    • Spreading of non-transformed and transformed cells
    • Vasilliev JM (1985): Spreading of non-transformed and transformed cells. Biochem Biophys Acta 780:21-65.
    • (1985) Biochem Biophys Acta , vol.780 , pp. 21-65
    • Vasilliev, J.M.1
  • 39
    • 0025316164 scopus 로고
    • Identification and characterization of C-terminal fragments of the β-amyloid precursor produced in cell culture
    • Wolf D, Quyon D, Wang Y, Cordell B (1990): Identification and characterization of C-terminal fragments of the β-amyloid precursor produced in cell culture. EMBO J 9:2079-2084.
    • (1990) EMBO J , vol.9 , pp. 2079-2084
    • Wolf, D.1    Quyon, D.2    Wang, Y.3    Cordell, B.4
  • 40
    • 0025636024 scopus 로고
    • On the organization of astrocytic gap junctions in rat brain as suggested by LM and EM immunohistochemistry of connexin43 expression
    • Yamamoto T, Ochalski A, Hertzberg EL, Nagy JI (1990): On the organization of astrocytic gap junctions in rat brain as suggested by LM and EM immunohistochemistry of connexin43 expression. J Comp Neurol 302.853-883.
    • (1990) J Comp Neurol , vol.302 , pp. 853-883
    • Yamamoto, T.1    Ochalski, A.2    Hertzberg, E.L.3    Nagy, J.I.4
  • 42
    • 0023845257 scopus 로고
    • Molecular cloning of amyloid cDNA derived from mRNA of the Alzheimer brain. Coding and noncoding regions of the fetal precursor mRNA are expressed in the Alzheimer cortex
    • Zain SB, Salim M, Chou W-G, Sajdel-Sulkowska EM, Majocha RE, Marotta CA (1988): Molecular cloning of amyloid cDNA derived from mRNA of the Alzheimer brain. Coding and noncoding regions of the fetal precursor mRNA are expressed in the Alzheimer cortex. Proc Natl Acad Sci USA 85:929-933.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 929-933
    • Zain, S.B.1    Salim, M.2    Chou, W.-G.3    Sajdel-Sulkowska, E.M.4    Majocha, R.E.5    Marotta, C.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.