Hepatocyte encapsulation - Initial intentions and new aspects for its use in bioartificial liver support

International Journal of Artificial Organs

Volumn 19, Issue 1, 1996, Pages 45-48

  Stange, J ^a   Mitzner, S ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

SUPPORTS;

BIOARTIFICIAL LIVER; HEPATOCYTES;

ARTIFICIAL ORGANS;

ANIMAL CELL; ARTIFICIAL LIVER; CONFERENCE PAPER; ENCAPSULATION; LIVER CELL; NONHUMAN;

EID: 0029916930     PISSN: 03913988     EISSN: None     Source Type: Journal    
DOI: 10.1177/039139889601900107     Document Type: Conference Paper

References (26)

1. Gislason G, Lobdell D, Kelly J, Sussmann N. A treatment system for implementing an extracorporeal liver assist device. Artif Organs 1994; 18: 385-9.
2. Sussman N, Kelly J. Improved liver function following treatment with an extracorporeal liver assist device. Artif Organs 1993; 17: 27-9.
3. Cattral M, Levy G. Artificial liver support-pipe dream or reality? New England Journal of Medicine 1994; 268-9.
4. Jauregui HO, Gann KL. Mammalian Hepatocytes as a Foundation for Treatment in Human Liver Failure. Journal of Cellular Biochemistry 1991; 45: 359-65.
5. Matsumura KN, Guevara GR, Hutson H, et al. Hybrid bioartificial liver in hepatic failure. Preliminary clinical report. Surgery 1987; 101: 99-103.
6. Michalopoulos G, Pilot HC. Primary culture of paren-chymal live cells on collagen membranes. Experimental Cell Research 1975; 94: 70-8.
7. Gerlach J, Stoll P, Schnoy B, Bücherl ES. Membranes as substrates for hepatocyte adhesion in liver support bioreactors. The International Journal of Artificial Organs 1990; 13: 436-41
8. Nyberg SL, Shatford RA, Peshwa MV, White JG, Cerra FB, Hu W-S. Evaluation of a hepatocyte-entrapment hollow fiber bioreactor. A Potential bioartificial liver. Biotechnology and Bioengineering 1993; 41: 194-203.
9. Demetriou AA, Reisner A, Sanchez J, Levenson SM, Moscioni AD Chowdhury JR. Transplantation of microcarrier-attached hepatocytes into 90% partially hepatectomized rats. Hepatology 1988; 8: 1006-9.
10. Gerlach J, Klöppel K, Schauwecker HH, Tauber R, Müller C, Bücherl ES. Use of hepatocytes in adhesion and suspension cultures for liver support bioreactors. The International Journal of Artificial Organs 1989; 12: 788-92.
11. Chang T. Artificial liver support based on artificial cells with emphasis on encapsulated hepatocytes. Artif Organs 1995; 16: 71-4.
12. Miura Y, Akimoto T, Fuke Y, Yamazaki S, Yagi K. In vitro maintenance of terminal-differentiated state in hepatocytes entrapped within calcium alginate. Artificial Organs 1987; 11: 361-5.
13. Stange J, Mitzner S, et al. Prolonged biochemical and morphological stability of encapsulated liver cells - a new method. Biomat, Artif Cell & Immob Biotech 1993; 21: 343-52.
14. Stange J, Bruegmann E, Falkenhagen D, Deutzenberg H, Dummler W, Ernst B. A new technique for encapsulation of liver microsomes. In: Whately, ed Microencapsulation of drugs. London Gordon & Breach, 1992; 257-8.
15. Wong H, Chang TMS. Bioartificial liver: implanted artificial cells microencapsulated living hepatocytes increases survival of liver failure rats. The International Journal of Artificial Organs 1986; 9: 335-6.
16. Frohburg E, Stözel U, Lenz K, Schäfer J-H, Tung LC, Riecken E-O. Prognostic indicators in fulminant hepatic failure. Z. Gastroenterol 1992; 30: 571-5.
17. Ringe B, Pichlmayr R, Lauchart W, Müller R. Indications and results of liver transplantation in acute hepatic failure. Transplantation Proceedings 1986; XVIII: 86-8.
18. Schwander JC, Hauri C, Zapf J, Froesch ER. Synthesis and secretion of insulin-like growth factor and its binding protein by the perfused rat liver. Dependence on growth hormone status. Endocrinology 1983; 113: 297.
19. Scott CD, Martin JL, Baxter RC. Production of insulin-like growth factor I and its binding protein by adult rat hepatocytes in primary culture. Endocrinology 1985; 116: 1094-1102.
20. Scott CD, Martin JL, Baxter RC. Rat hepatocyte insulin-like growth factor I and binding protein. Effect of growth hormone in vitro and in vivo. Endocrinology 1985; 116: 1102-7.
21. Oka Y, Orth D. Human plasma epidermal growth factor/β-Urogastrone is associated with blood platelets. J Clin Invest 1983; 72: 249.
22. Bucher NLR, Robinson G, Farmer SR. Effects of extra-cellular matrix on hepatocytes growth and gene expression. Implications for hepatic regeneration and the repair of liver injury. Seminars in liver disease 1990; 10(1): 11-9.
23. Dunn J, Tompkins R, Yarmush M. Hepatocytes in collagen sandwich: evidence for transcriptional and translation regulation. Journal of Cell Biology 1992; 116: 1043-53.
24. Clement B, Guguen-Goillouzu C, Campion JP, Claise D, Bourel M, Goillouzu A. Long-term co-cultures of adult human hepatocytes with rat liver epithelial cells: modulation of albumin secretion and accumulation of extracellular material. Hepatology 1984; 4(3): 373-80.
25. Michalopoulos G, Pilot HC. Primary culture of parenchymal liver cells on collagen membranes. Experimental Cell Research 1975; 94: 70-8.
26. Stange J. Development of a processor-regulated bioreactor on the base of microencapsulated hepatocytes. Biotechnology-Report of the German Research Ministry 1994, in press 1995.