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Volumn 2, Issue 2, 1996, Pages 319-330

Clinical and immimological effects of granulocyte-macrophage colony-stimulating factor coadministered with interleukin 2: A phase IB study

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA DR ANTIGEN; INTERLEUKIN 2; RECOMBINANT INTERLEUKIN 2;

EID: 0029916896     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (39)

References (50)
  • 1
    • 0025190051 scopus 로고
    • Lymphokines and cytokines as cancer treatment, immunotherapy realized
    • Phila.
    • Borden, E , and Sondel, P. Lymphokines and cytokines as cancer treatment, immunotherapy realized. Cancer (Phila.), 65: 800-814, 1990.
    • (1990) Cancer , vol.65 , pp. 800-814
    • Borden, E.1    Sondel, P.2
  • 2
    • 0023751402 scopus 로고
    • New approaches to the immunotherapy of cancer using interleukin-2
    • Rosenberg, S. New approaches to the immunotherapy of cancer using interleukin-2. Ann. Intern. Med , 108: 853-864, 1988.
    • (1988) Ann. Intern. Med , vol.108 , pp. 853-864
    • Rosenberg, S.1
  • 3
    • 0027522021 scopus 로고
    • Interleukin-2, a review of its pharmacologic properties and therapeutic use in patients with cancer
    • Whittington, R., and Faulds, D. Interleukin-2, a review of its pharmacologic properties and therapeutic use in patients with cancer. Drugs, 46: 446-514, 1993.
    • (1993) Drugs , vol.46 , pp. 446-514
    • Whittington, R.1    Faulds, D.2
  • 4
    • 0028332155 scopus 로고
    • Effects of route and formulation on clinical pharmacokinetics of interleukin-2
    • Anderson, P. M., and Sorenson, M. A. Effects of route and formulation on clinical pharmacokinetics of interleukin-2. Clin. Pharmacokinet., 27: 19-31, 1994
    • (1994) Clin. Pharmacokinet. , vol.27 , pp. 19-31
    • Anderson, P.M.1    Sorenson, M.A.2
  • 6
    • 0020031140 scopus 로고
    • Augmentation of the antitumor therapeutic efficacy of long-term cultured T lymphocytes by in vitro administration of purified interleukin-2
    • Cheever, M., Greenberg, P., Fefer, A , and Gillis, S. Augmentation of the antitumor therapeutic efficacy of long-term cultured T lymphocytes by in vitro administration of purified interleukin-2 J. Exp. Med., 155: 968-980, 1982.
    • (1982) J. Exp. Med. , vol.155 , pp. 968-980
    • Cheever, M.1    Greenberg, P.2    Fefer, A.3    Gillis, S.4
  • 7
    • 0023937203 scopus 로고
    • In vivo induction of the lymphokine-activated killer phenomenon: Interleukin 2-dependent human non-major histocompatibility complex-restricted cytotoxicity generated in vivo during administration of human recombinant interleukin 2
    • Hank, J., Kohler, P., Hillman, G , Rosenthal, N., Moore, K., Storer, B., Minkoff, D., Bradshaw, J., Bechhofer, R., and Sondel, P. In vivo induction of the lymphokine-activated killer phenomenon: interleukin 2-dependent human non-major histocompatibility complex-restricted cytotoxicity generated in vivo during administration of human recombinant interleukin 2. Cancer Res., 48: 1965-1971, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 1965-1971
    • Hank, J.1    Kohler, P.2    Hillman, G.3    Rosenthal, N.4    Moore, K.5    Storer, B.6    Minkoff, D.7    Bradshaw, J.8    Bechhofer, R.9    Sondel, P.10
  • 8
    • 0023804208 scopus 로고
    • Repetitive weekly cycles of interleukin-2. II. Clinical and immunological effects of dose, schedule, and addition of indomethacin
    • Sosman, J. A., Kohler, P. C., Hank, J., Moore, K. H., Bechhofer, R., Storer, B., and Sondel, P. M. Repetitive weekly cycles of interleukin-2. II. Clinical and immunological effects of dose, schedule, and addition of indomethacin. J. Natl. Cancer Inst., 80: 1451-1461, 1988.
    • (1988) J. Natl. Cancer Inst. , vol.80 , pp. 1451-1461
    • Sosman, J.A.1    Kohler, P.C.2    Hank, J.3    Moore, K.H.4    Bechhofer, R.5    Storer, B.6    Sondel, P.M.7
  • 9
    • 0025091247 scopus 로고
    • Augmentation of antibody dependent cell mediated cytotoxicity following in vivo therapy with recombinant interleukin 2
    • Hank, J., Robinson, R., Surfus, J., Mueller, B., Reisfeld, R., Cheung, N., and Sondel, P. Augmentation of antibody dependent cell mediated cytotoxicity following in vivo therapy with recombinant interleukin 2. Cancer Res., 50: 5234-5239, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 5234-5239
    • Hank, J.1    Robinson, R.2    Surfus, J.3    Mueller, B.4    Reisfeld, R.5    Cheung, N.6    Sondel, P.7
  • 10
    • 0019022864 scopus 로고
    • The functional relationship of the interleukins
    • Smith, K., Lachman, L., Oppenheim, J., and Favata, M. The functional relationship of the interleukins. J. Exp. Med., 154: 1551-1556, 1980.
    • (1980) J. Exp. Med. , vol.154 , pp. 1551-1556
    • Smith, K.1    Lachman, L.2    Oppenheim, J.3    Favata, M.4
  • 11
    • 0026813323 scopus 로고
    • The immunotherapy and gene therapy of cancer
    • Rosenberg, S. A. The immunotherapy and gene therapy of cancer. J. Clin. Oncol., 10: 180-199, 1992.
    • (1992) J. Clin. Oncol. , vol.10 , pp. 180-199
    • Rosenberg, S.A.1
  • 14
    • 0024311016 scopus 로고
    • Phase I clinical trial of interleukin 2 and α-interferon: Toxicity and immunologic effects
    • Budd, G. T., Osgood, B., Barna, B., and Bukowski, R. M. Phase I clinical trial of interleukin 2 and α-interferon: toxicity and immunologic effects. Cancer Res., 49: 6432-6436, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 6432-6436
    • Budd, G.T.1    Osgood, B.2    Barna, B.3    Bukowski, R.M.4
  • 17
    • 3042934146 scopus 로고
    • The molecular biology and functions of the granulocyte-macrophage colony stimulating factors
    • Metcalf, D. The molecular biology and functions of the granulocyte-macrophage colony stimulating factors. Blood 67: 35-43, 1987.
    • (1987) Blood , vol.67 , pp. 35-43
    • Metcalf, D.1
  • 18
    • 0025331307 scopus 로고
    • Effects of parenteral recombinant human macrophage colony-stimulating factor on monocyte number, phenotype, and antitumor cytotoxicity in nonhuman primates
    • Munn, D., Garnick, M., and Cheung, N. Effects of parenteral recombinant human macrophage colony-stimulating factor on monocyte number, phenotype, and antitumor cytotoxicity in nonhuman primates. Blood, 75. 2042-2048, 1990.
    • (1990) Blood , vol.75 , pp. 2042-2048
    • Munn, D.1    Garnick, M.2    Cheung, N.3
  • 19
    • 0025326953 scopus 로고
    • Phagocytosis of rumor cells by human monocytes cultured in recombinant macrophage colony stimulating factor
    • Munn, D., and Cheung, N-K. Phagocytosis of rumor cells by human monocytes cultured in recombinant macrophage colony stimulating factor. J. Exp. Med., 172: 231-237, 1990.
    • (1990) J. Exp. Med. , vol.172 , pp. 231-237
    • Munn, D.1    Cheung, N.-K.2
  • 20
    • 0024378215 scopus 로고
    • Antibody-dependent antitumor cytotoxicity by human monocytes cultured with recombinant macrophage colony-stimulating factor
    • Munn, D., and Cheung, N. Antibody-dependent antitumor cytotoxicity by human monocytes cultured with recombinant macrophage colony-stimulating factor. J. Exp. Med., 170: 511-526, 1989.
    • (1989) J. Exp. Med. , vol.170 , pp. 511-526
    • Munn, D.1    Cheung, N.2
  • 21
    • 0022478367 scopus 로고
    • Induction of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor
    • Washington DC
    • Grabstein, K., Urdal, D., Tushinski, R., Mochizuki, D., Price, V., Cantrell, M., Gillis, S., and Conlon, P. Induction of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor. Science (Washington DC), 232: 506-508, 1986.
    • (1986) Science , vol.232 , pp. 506-508
    • Grabstein, K.1    Urdal, D.2    Tushinski, R.3    Mochizuki, D.4    Price, V.5    Cantrell, M.6    Gillis, S.7    Conlon, P.8
  • 22
    • 0026019353 scopus 로고
    • Induction of cytokine messenger RNA and secretion in alveolar macrophages and blood monocytes from patients with lung cancer receiving granulocyte-macrophage colony-stimulating factor
    • Thomassen, M., Ahmad, M., Barna, B., Antal, J., Wiedmann, H., Meeker, D , Klein, J., Bauer, L., Gibson, V., Andresen, S., and Bukowski, R. Induction of cytokine messenger RNA and secretion in alveolar macrophages and blood monocytes from patients with lung cancer receiving granulocyte-macrophage colony-stimulating factor. Cancer Res., 51: 857-862, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 857-862
    • Thomassen, M.1    Ahmad, M.2    Barna, B.3    Antal, J.4    Wiedmann, H.5    Meeker, D.6    Klein, J.7    Bauer, L.8    Gibson, V.9    Andresen, S.10    Bukowski, R.11
  • 23
    • 0023948373 scopus 로고
    • Response of resident murine peritoneal macrophages to in vivo administration of granulocyte-macrophage colony-stimulating factor
    • Morrissey, P., Bressler, L., Charrier, K., and Alpert, A. Response of resident murine peritoneal macrophages to in vivo administration of granulocyte-macrophage colony-stimulating factor. J. Immunol., 140: 1910-1915, 1988.
    • (1988) J. Immunol. , vol.140 , pp. 1910-1915
    • Morrissey, P.1    Bressler, L.2    Charrier, K.3    Alpert, A.4
  • 24
    • 0027209079 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor-induced antibody-dependent cellular cytotoxicity in bone marrow macrophages: Application in bone marrow transplantation
    • Charak, B., Agah, R., and Mazumder, A. Granulocyte-macrophage colony-stimulating factor-induced antibody-dependent cellular cytotoxicity in bone marrow macrophages: application in bone marrow transplantation. Blood, 81: 3474-3479, 1993.
    • (1993) Blood , vol.81 , pp. 3474-3479
    • Charak, B.1    Agah, R.2    Mazumder, A.3
  • 25
    • 0026629579 scopus 로고
    • In vivo administration of recombinant macrophage colony-stimulating factor induces macrophage-mediated antibody-dependent cytotoxicity of tumor cells
    • Sanda, M., Bolton, E., Mulé, J. J., and Rosenberg, S. A. In vivo administration of recombinant macrophage colony-stimulating factor induces macrophage-mediated antibody-dependent cytotoxicity of tumor cells. J. Immunother., 12: 132-137, 1992.
    • (1992) J. Immunother. , vol.12 , pp. 132-137
    • Sanda, M.1    Bolton, E.2    Mulé, J.J.3    Rosenberg, S.A.4
  • 26
    • 0028202926 scopus 로고
    • Monocyte activation following systemic administration of granulocyte-macrophage colony-stimulating factor
    • Chachoua, A., Oratz, R., Hoogmoed, R., Caron, D., Peace, D., Liebes, L., Blum, R., and Vilcek, J. Monocyte activation following systemic administration of granulocyte-macrophage colony-stimulating factor. J. Imunother., 15: 217-224, 1994.
    • (1994) J. Imunother. , vol.15 , pp. 217-224
    • Chachoua, A.1    Oratz, R.2    Hoogmoed, R.3    Caron, D.4    Peace, D.5    Liebes, L.6    Blum, R.7    Vilcek, J.8
  • 27
    • 0023893965 scopus 로고
    • Effect of recombinant granulocyte/macrophage colony-stimulating factor on human monocyte activity in vitro and following intravenous administration
    • Kleinerman, E., Knowles, R., Lachman, L., and Gutterman, J. Effect of recombinant granulocyte/macrophage colony-stimulating factor on human monocyte activity in vitro and following intravenous administration. Cancer Res., 48: 2604-2609, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 2604-2609
    • Kleinerman, E.1    Knowles, R.2    Lachman, L.3    Gutterman, J.4
  • 28
    • 0027982452 scopus 로고
    • Phase I trial of recombinant macrophage colony-stimulating factor and recombinant γ interferon: Toxicity, monocytosis, and clinical effects
    • Weiner, L., Li, W., Holmes, M., Catalono, R., Dovnarsky, M., Padavic, K., and Alpaugh, R. Phase I trial of recombinant macrophage colony-stimulating factor and recombinant γ interferon: toxicity, monocytosis, and clinical effects. Cancer Res., 54: 4084-4090, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 4084-4090
    • Weiner, L.1    Li, W.2    Holmes, M.3    Catalono, R.4    Dovnarsky, M.5    Padavic, K.6    Alpaugh, R.7
  • 29
    • 0023821499 scopus 로고
    • The international standard for human interleukin-2: Calibration by international collaborative study
    • Gearing, A. J. H., and Thorpe, R. The international standard for human interleukin-2: calibration by international collaborative study. J. Immunol. Methods. 114: 3-9, 1988.
    • (1988) J. Immunol. Methods , vol.114 , pp. 3-9
    • Gearing, A.J.H.1    Thorpe, R.2
  • 30
    • 0024308235 scopus 로고
    • Lymphokine-activated killer activity induced by in vivo interleukin 2 therapy: Predominant role for lymphocytes with increased expression of CD2 and Leu19 antigens but negative expression of CD16 antigens
    • Weil-Hillman, G., Fisch, P., Prieve, A. F., Sosman, J. A., Hank, J. A., and Sondel, P. M. Lymphokine-activated killer activity induced by in vivo interleukin 2 therapy: predominant role for lymphocytes with increased expression of CD2 and Leu19 antigens but negative expression of CD16 antigens. Cancer Res., 49: 3680-3688, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 3680-3688
    • Weil-Hillman, G.1    Fisch, P.2    Prieve, A.F.3    Sosman, J.A.4    Hank, J.A.5    Sondel, P.M.6
  • 31
    • 0025783318 scopus 로고
    • Biological and antitumor effects of recombinant human macrophage colony-stimulating factor in mice
    • Bock, S., Cameron, R., Kragel, P., Mule, J., and Rosenberg, S. Biological and antitumor effects of recombinant human macrophage colony-stimulating factor in mice. Cancer Res., 51: 2649-2654, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 2649-2654
    • Bock, S.1    Cameron, R.2    Kragel, P.3    Mule, J.4    Rosenberg, S.5
  • 32
    • 0029037056 scopus 로고
    • Macrophage colony-stimulating factor complementary DNA: A candidate for gene therapy in metastatic melanoma
    • Walsh, P., Dorner, A., Duke, R. C., Su, L. J., and Glode, L. M. Macrophage colony-stimulating factor complementary DNA: a candidate for gene therapy in metastatic melanoma. J. Natl. Cancer Inst., 87: 809-816, 1995.
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 809-816
    • Walsh, P.1    Dorner, A.2    Duke, R.C.3    Su, L.J.4    Glode, L.M.5
  • 34
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony stimulating factor stimulates potent, specific, and long-lasting antitumor immunity
    • Dranoff, G , Jaffee, E., Lazenby, A., Golumbek, P., Levitsky, H., Brose, K., Jackson, V., Hamada, H , Pardoll, D., and Mulligan, R. C. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony stimulating factor stimulates potent, specific, and long-lasting antitumor immunity. Proc. Natl. Acad. Sci. USA, 90: 3539-3543, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3    Golumbek, P.4    Levitsky, H.5    Brose, K.6    Jackson, V.7    Hamada, H.8    Pardoll, D.9    Mulligan, R.C.10
  • 37
    • 0026598776 scopus 로고
    • A phase I trial of recombinant human macrophage colony-stimulating factor by rapid intravenous infusion in patients with refractory malignancy
    • Zamkoff, K., Hudson, J., Groves, E., Childs, A., Konrad, M., and Rudolph, A. A phase I trial of recombinant human macrophage colony-stimulating factor by rapid intravenous infusion in patients with refractory malignancy. J. Immunother., 11: 103-110, 1992.
    • (1992) J. Immunother. , vol.11 , pp. 103-110
    • Zamkoff, K.1    Hudson, J.2    Groves, E.3    Childs, A.4    Konrad, M.5    Rudolph, A.6
  • 38
    • 0027232453 scopus 로고
    • The therapeutic use of the unconjugated monoclonal antibodies (MAb) 17-1A in combination with GM-CSF in the treatment of colorectal carcinoma (CRC)
    • Ragnhammar, P., Magnusson, I., Masucci, G., and Mellstedt, H. The therapeutic use of the unconjugated monoclonal antibodies (MAb) 17-1A in combination with GM-CSF in the treatment of colorectal carcinoma (CRC). Med. Oncol. Tumor Pharmacother., 10: 61-70, 1993.
    • (1993) Med. Oncol. Tumor Pharmacother. , vol.10 , pp. 61-70
    • Ragnhammar, P.1    Magnusson, I.2    Masucci, G.3    Mellstedt, H.4
  • 39
    • 0027482755 scopus 로고
    • Recombinant granulocyte colony-stimulating factor administration to healthy volunteers: Induction of immunophenotypically and functionally altered neutrophils via an effect on myeloid progenitor cells
    • Kerst, J. M., de Haas, M., van der Schoot, C. E., Slaper-Cortenbach, I. C , Kleijer, M., von dem Borne, A. E., and van Oers, W. H. Recombinant granulocyte colony-stimulating factor administration to healthy volunteers: induction of immunophenotypically and functionally altered neutrophils via an effect on myeloid progenitor cells. Blood. 82: 3265-3272, 1993.
    • (1993) Blood , vol.82 , pp. 3265-3272
    • Kerst, J.M.1    De Haas, M.2    Van Der Schoot, C.E.3    Slaper-Cortenbach, I.C.4    Kleijer, M.5    Von Dem Borne, A.E.6    Van Oers, W.H.7
  • 40
    • 0027304602 scopus 로고
    • Involvement of the high-affinity receptor for IgG (Fc gamma RI; CD64) in enhanced tumor cell cytotoxicity of neutrophils during granulocyte colony-stimulating factor therapy
    • Valerius, T., Repp, R., deWit, T. P., Berthold, S., Platzer, E., Kalden, J. R., Gramatzki, M., and van de Winkel, J. G. Involvement of the high-affinity receptor for IgG (Fc gamma RI; CD64) in enhanced tumor cell cytotoxicity of neutrophils during granulocyte colony-stimulating factor therapy. Blood. 82: 931-939, 1993
    • (1993) Blood , vol.82 , pp. 931-939
    • Valerius, T.1    Repp, R.2    DeWit, T.P.3    Berthold, S.4    Platzer, E.5    Kalden, J.R.6    Gramatzki, M.7    Van De Winkel, J.G.8
  • 41
    • 0025176662 scopus 로고
    • Activation of lymphocytes induced by recombinant human granulocyte-macrophage colony-stimulating factor in patients with malignant lymphoma
    • Ho, A. D., Haas, R., Wulf, G., Knauf, W., Ehrhardt, R., Heilig, B., Körbling, M., Schulz, G., and Hunstein, W. Activation of lymphocytes induced by recombinant human granulocyte-macrophage colony-stimulating factor in patients with malignant lymphoma. Blood, 75: 203-212, 1990.
    • (1990) Blood , vol.75 , pp. 203-212
    • Ho, A.D.1    Haas, R.2    Wulf, G.3    Knauf, W.4    Ehrhardt, R.5    Heilig, B.6    Körbling, M.7    Schulz, G.8    Hunstein, W.9
  • 42
    • 0023821508 scopus 로고
    • Amplification of IL-2-driven T cell proliferation by recombinant human IL-3 and granulocyte-macrophage colony-stimulating factor
    • Santoli, D., Clark, S. C., Kreider, B. L., Maslin, P. A., and Rovera G. Amplification of IL-2-driven T cell proliferation by recombinant human IL-3 and granulocyte-macrophage colony-stimulating factor. J. Immunol., 141: 519-526, 1988
    • (1988) J. Immunol. , vol.141 , pp. 519-526
    • Santoli, D.1    Clark, S.C.2    Kreider, B.L.3    Maslin, P.A.4    Rovera, G.5
  • 43
    • 0027212418 scopus 로고
    • Effect of granulocyte-macrophage colony-stimulating factor on lymphokine-activated killer cell induction
    • Stewart-Akers, A. M., Cairns, J. S., Tweardy, D. J., and McCarthy, S. A. Effect of granulocyte-macrophage colony-stimulating factor on lymphokine-activated killer cell induction. Blood, 81: 2671-2678, 1993.
    • (1993) Blood , vol.81 , pp. 2671-2678
    • Stewart-Akers, A.M.1    Cairns, J.S.2    Tweardy, D.J.3    McCarthy, S.A.4
  • 44
    • 25744472585 scopus 로고
    • Multiple cerebral lesions complicating therapy with interleukin-2
    • Karp, B., Yang, J., and Khorsand, M. Multiple cerebral lesions complicating therapy with interleukin-2 (Abstract). Neurology, 45 (Suppl. 4): A400, 1995.
    • (1995) Neurology , vol.45 , Issue.4 SUPPL.
    • Karp, B.1    Yang, J.2    Khorsand, M.3
  • 45
    • 0021965080 scopus 로고
    • Neurologic dysfunction in the idiopathic hypereosinophilic syndrome
    • Moore, P. M., Harley, J. B., and Fauci, A. S. Neurologic dysfunction in the idiopathic hypereosinophilic syndrome. Ann. Intern. Med., 102: 109-114, 1985.
    • (1985) Ann. Intern. Med. , vol.102 , pp. 109-114
    • Moore, P.M.1    Harley, J.B.2    Fauci, A.S.3
  • 46
    • 0015048032 scopus 로고
    • Loffler's eosinophilic endocarditis with Balint's syndrome
    • Gardner-Thorpe, G., Harriman, D. G., Parsons, M., and Rudge, P. Loffler's eosinophilic endocarditis with Balint's syndrome. Q. J. Med. 40: 249-260, 1971.
    • (1971) Q. J. Med. , vol.40 , pp. 249-260
    • Gardner-Thorpe, G.1    Harriman, D.G.2    Parsons, M.3    Rudge, P.4
  • 47
    • 0027175429 scopus 로고
    • Eosinophil cationic granule proteins impair thrombomodulin function a potential mechanism for thromboembolism in hypereosinophilic heart disease
    • Slungaard, A., Vercellotti, G. M., Tran, T., Gleich, G. J., and Key, N. S. Eosinophil cationic granule proteins impair thrombomodulin function A potential mechanism for thromboembolism in hypereosinophilic heart disease. J. Clin. Invest., 91: 1721-1730, 1993.
    • (1993) J. Clin. Invest. , vol.91 , pp. 1721-1730
    • Slungaard, A.1    Vercellotti, G.M.2    Tran, T.3    Gleich, G.J.4    Key, N.S.5
  • 48
    • 0025174705 scopus 로고
    • Structure and function of thrombomodulin: A natural anticoagulant
    • Dittman, W. A., and Majerus, P. W. Structure and function of thrombomodulin: a natural anticoagulant. Blood 75: 329-336, 1990.
    • (1990) Blood , vol.75 , pp. 329-336
    • Dittman, W.A.1    Majerus, P.W.2
  • 49
    • 0024558370 scopus 로고
    • The roles of protein C and thrombomodulin in the regulation of blood coagulation
    • Esmon, C. T. The roles of protein C and thrombomodulin in the regulation of blood coagulation. J. Biol. Chem., 264: 4743-4746, 1989.
    • (1989) J. Biol. Chem. , vol.264 , pp. 4743-4746
    • Esmon, C.T.1
  • 50
    • 0021929962 scopus 로고
    • Thrombomodulin is found on endothelium of arteries, veins, capillaries, and lymphatics and syncytiotrophoblast of human placenta
    • Maruyama, I., Bell, C. E., and Majerus, P. W. Thrombomodulin is found on endothelium of arteries, veins, capillaries, and lymphatics and syncytiotrophoblast of human placenta. J. Cell Biol. 101: 363-371, 1985.
    • (1985) J. Cell Biol. , vol.101 , pp. 363-371
    • Maruyama, I.1    Bell, C.E.2    Majerus, P.W.3


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