Lateralization of brain function in childhood revealed by magnetic resonance spectroscopy

Neurology

Volumn 46, Issue 4, 1996, Pages 974-977

  Gadian, D G ^a   Isaacs, E B ^a   Cross, J H ^a   Connelly, A ^a   Jackson, G D ^a   King, M D ^a   Neville, B G R ^a   Vargha Khadem, F ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b GREAT ORMOND STREET HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ARTICLE; BRAIN FUNCTION; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; COGNITIVE DEFECT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DATA ANALYSIS; DIAGNOSTIC VALUE; HEMISPHERIC DOMINANCE; HUMAN; IMAGE ANALYSIS; INTELLIGENCE QUOTIENT; MEMORY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; TEMPORAL LOBE EPILEPSY;

EID: 0029916606     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.46.4.974     Document Type: Article

References (19)

1. Koller JK, Zaczek R, Coyle JT. N-acetyl-aspartyl-glutamate: regional levels in rat brain and the effects of brain lesions as determined by a new HPLC method. J Neurochem 1984;43: 1136-1142.
2. Moffett JR, Namboodiri MA, Cangro CB, Neale JH. Immunohistochemical localization of N-acetylaspartate in rat brain. Neuroreport 1991;2:131-134.
3. Urenjak J, Williams SR, Gadian DG, Noble M. Specific expression of N-acetyl-aspartate in neurons, oligodendrocyte-type-2 astrocyte progenitors and immature oligodendrocytes in vitro. J Neurochem 1992;59:55-61.
4. Urenjak J, Williams SR, Gadian DG, Noble M. Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types. J Neurosci 1993;13:981-989.
5. Bruhn H, Frahm J, Gyngell ML, Merboldt KD, Hanicke W, Sauter R. Cerebral metabolism in man after acute stroke: new observations using localised proton NMR spectroscopy. Magn Reson Med 1989;9:126-131.
6. Luyten PR, Marien AJH, Heindel W, et al. Metabolic imaging of patients with intracranial tumours: H-1 MR spectroscopic imaging and PET. Radiology 1990;176:791-799.
7. Chong WK, Sweeney B, Wilkinson ID, et al. Proton spectroscopy of the brain in HIV infection: correlation with clinical, immunologic, and MR imaging findings. Radiology 1993;188: 119-124.
8. Hugg JW, Laxer KD, Matson GB, Maudsley AA, Weiner MW. Neuron loss localizes human focal epilepsy by in vivo proton MR spectroscopic imaging. Ann Neurol 1993;34:788-794.
9. Cendes F, Andermann F, Preul MC, Arnold DL. Lateralization of temporal lobe epilepsy based on regional metabolic abnormalities in proton magnetic resonance spectroscopic images. Ann Neurol 1994;35:211-216.
10. 1H magnetic resonance spectroscopy in the investigation of intractable epilepsy. Acta Neurol Scand Suppl 1994;152:116-121.
11. Connelly A, Jackson GD, Duncan JS, King MD, Gadian DG. Magnetic resonance spectroscopy in temporal lobe epilepsy. Neurology 1994;44:1411-1417.
12. Milner B. Psychological aspects of focal epilepsy and its neurosurgical management. Adv Neurol 1975;8:299-321.
13. Cross JH, Jackson GD, Neville BGR, et al. Early detection of abnormalities in partial epilepsy using magnetic resonance. Arch Dis Child 1993;69:104-109.
14. 2 relaxometry. Neurology 1993;43:1793-1799.
15. Lezak MD. Neuropsychological assessment. 2nd ed. Oxford: Oxford University Press, 1983.
16. Wechsler D, Stone CP. Wechsler Memory Scale. San Antonio, TX: Psychological Corporation, 1945.
17. Klose U. In vivo proton spectroscopy in presence of eddy currents. Magn Reson Med 1990;14:26-30.
18. Jambaque I, Dellatolas G, Dulac O, Ponsot G, Signoret J-L. Verbal and visual memory impairment in children with epilepsy. Neuropsychologia 1993;31:1321-1337.
19. Vargha-Khadem F, Isaacs E, Muter V. A review of cognitive outcome after unilateral lesions sustained during childhood. J Child Neurol 1994;9(suppl 2):2S67-2S73.