'Blind' multicenter evaluation of the prognostic value of DNA image cytometric and morphometric features in invasive breast cancer

Analytical Cellular Pathology

Volumn 10, Issue 2, 1996, Pages 85-99

  Theissig, F ^a   Baak, J P A ^b   Schuurmans, L ^b   Haroske, G ^a   Meyer, W ^a   Kunze, K D ^a  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Breast cancer; DNA image cytometry; Morphometry; Prognosis

Indexed keywords

DNA;

ARTICLE; BREAST CANCER; CONTROLLED STUDY; CYTOMETRY; FEMALE; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; MAJOR CLINICAL STUDY; MORPHOMETRICS; PRIORITY JOURNAL; PROGNOSIS;

BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; DNA, NEOPLASM; FEMALE; HUMANS; LYMPHATIC METASTASIS; NEOPLASM INVASIVENESS; NEOPLASM STAGING; OBSERVER VARIATION; PROGNOSIS; SURVIVAL RATE; TIME FACTORS;

EID: 0029916342     PISSN: 09218912     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Atkin NB, Kay R. Prognostic significance of modal DNA value and other factors in malignant tumors, based on 1465 cases. Br J Cancer 1979; 40: 210-221.
2. Auer G, Caspersson T, Wallgren AS. DNA content and survival in mammary carcinoma. Anal Quant Cytol 1980; 2: 161-165.
3. Baak JPA, van Dop H, Kurver PHJ, Hermans J. The value of morphometry of classic prognosticators in breast cancer. Cancer 1985; 56: 374-382.
4. Baak JPA, van Diest PJ, Ariens AT, Beek PDM et al. The Multicenter Morphometric Mammary Carcinoma Project (MMMCP). A nationwide prospective study on reprodu-cibility and prognostic power of routine quantitative assessments in the Netherlands. Pathol Res Pract 1989; 185: 664-670.
5. Baak JPA, Chin D, van Diest PJ, Ortiz R, Matze-Cok P, Bacus SS. Comparative long-term prognostic value of quantitative HER-2/neu protein expression, DNA ploidy, and morphometric and clinical features in paraffin-embedded invasive breast cancer. Lab Invest 1991; 64: 215-223.
6. Baak JPA, van Diest PJ, Benraadt J, Matze-Cok E, Brugghe J, Schuurmans LT, Littooij JJ, MMMCP Collaborators. The multi-center morphometric mammary carcinoma project (MMMCP) in the Netherlands: value of morphometrically assessed proliferation and differentiation. J Cell Biochem. In press.
7. Bloom HJG, Richardson WW. Histological grading and prognosis in breast cancer. Br J Cancer 1957; 11: 359-377.
8. Böcking A, Adler CF, Common HH, Hilgarth M, Granzen B, Auffermann W. Algorithm for a DNA-cytophoto-metric diagnosis and grading of malignancy. Anal Quant Cytol 1984; 6: 1-8.
9. Böcking A, Chatelain R, Biesterfeld S, Noll E, Biesterfeld D, Wohltmann D, Goecke G. DNA grading of malignancy in breast cancer: prognostic validity reproducibility and comparison with other classifications. Anal Quant Cytol Histol 1989; 11: 73-80.
10. van Diest PJ, Baak JPA. The morphometric prognostic index is the strongest prognosticator in premenopausal lymph node-negative and lymph node-positive breast cancer patients. Hum Pathol 1991; 22: 326-330.
11. van Diest PJ, Baak JPA, Matze-Cok P, Wisse-Brekelmans ECM, van Galen CM, Kurver PHJ et al. Reproducibility of mitosis counting in 2469 breast cancer specimens: results from the multicenter morphometric mammary carcinoma project. Hum Pathol 1992; 23: 603-607.
12. Haroske G, Kunze KD, Dimmer V, Meyer W, Theissig F. Feasibility and limitations of cytometric DNA ploidy analysis procedures in tissue sections. Zentbl Pathol 1994; 139: 407-417.
13. Kunze KD, Haroske G, Dimmer V, Meyer W, Theissig F. Grading and prognosis of invasive ductal mammary carcinoma by nuclear image analysis in tissue sections. Pathol Res Pract 1989; 185: 689-693.
14. Kunze KD, Haroske G, Dimmer V, Meyer W, Theissig F. Quantitative morphology of primary and metastatic tumor. Comparative studies on tissue sections. Anal Cell Pathol 1989; 1: 143-151.
15. van der Linden HC, Baak JPA, Lindeman J et al. Prospective evaluation of the prognostic value of morphometry in primary breast cancer patients. J Clin Pathol 1987; 40: 302-306.
16. van der Lindeman JC, Baak JPA, Meijer CJLM, Herman C.J. The multivariate prognostic index and nuclear DNA content are independent prognostic factors in primary breast cancer patients. Cytometry 1989; 10: 56-61.
17. Siitonen GM, Kallioniemi O-P, Helin HJ, Isola JJ. Prognostic value of cells with more than 5c DNA content in node-negative breast cancer as determined by image cytometry from tissue sections. Hum Pathol 1993; 24: 1348-1353.
18. Theissig F, Kunze KD, Haroske G, Meyer W. Histological grading of breast cancer: interobserver reproducibility and prognostic significance. Pathol Res Pract 1990; 186: 732-736.
19. Theissig F, Dimmer V, Haroske G, Kunze KD, Meyer W. Use of nuclear image cytometry, histopathologjcal grading and DNA cytometry to make breast cancer prognosis more objective. Anal Cell Pathol 1991; 3: 351-360.
20. Tosi P, Luzi P, Sforza V, Santopietro R, Baak JPA. Correlation between morphometrical parameters and disease free-survival in ductal breast cancer treated only by surgery. Appl Pathol 1986; 4: 33-42.
21. Uyterlinde AM, Baak JPA, Schipper NW, Peterse H, Matze E, Meijer CJLM. Further evaluation of the prognostic value of morphometric and flow cytometric parameters in breast-cancer patients with long follow-up. Int J Cancer 1990; 45: 1-7.
22. Uyterlinde AM, Baak JPA, Schipper NW, Peters HJ, Meijer JWR, Vooijs PG, Matze E. Prognostic value of morphometry and DNA flow-cytometry features of invasive breast cancers detected by population screening: comparison with control group of hospital patients. Int J Cancer 1991; 48: 173-181.