S-phase fraction identifies high-risk subgroups among DNA-diploid breast cancers

Breast Cancer Research and Treatment

Volumn 38, Issue 3, 1996, Pages 265-275

  Romero, H ^a,b   Schneider, J ^a,c   Burgos, J ^a   Bilbao, J ^a   Rodriguez Escudero, F J ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b UNIVERSIDAD DEL CAUCA   (Colombia)

^c HOSPITAL DE CRUCES   (Spain)

Author keywords

Breast; Cancer; DNA content; Flow cytometry; Prognosis

Indexed keywords

ANEUPLOIDY; ARTICLE; BREAST CANCER; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CELL CYCLE S PHASE; DIPLOIDY; DNA CONTENT; FEMALE; FLOW CYTOMETRY; HIGH RISK POPULATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RETROSPECTIVE STUDY;

ADULT; AGED; AGED, 80 AND OVER; ANEUPLOIDY; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; DIPLOIDY; DISEASE-FREE SURVIVAL; FEMALE; FLOW CYTOMETRY; HUMANS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MULTIVARIATE ANALYSIS; S PHASE;

EID: 0029915985     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01806145     Document Type: Article

References (37)

1. Fisher B, Ravdin RG, Austrian RK, Slack NH, Moore GE, Noer RJ: Surgical adjuvant chemotherapy in cancer of the breast: results of a decade of cooperative investigation. Ann Surg 168: 337-356, 1968
2. Frierson HF Jr: Ploidy analysis and S-phase fraction determination by flow cytometry of invasive adenocarcinomas of the breast. Am J Surg Pathol 15: 358-367, 1941
3. Page DL: Prognosis and breast cancer. Recognition of lethal and favorable prognostic types. Am J Surg Pathol 15: 334-349, 1991
4. Shankey TV, Ravinovitch PS, Bruce B, Bauer K, Cox C, Duque RE, Hedley DW, Mayall BH, Wheeless L: Guidelines for the implementation of clinical DNA cytometry. Breast Cancer Res Treat 28: 61-68, 1993
5. Hedley DW, Clark GM, Cornelisse C, Killander D, Kute T, Merkel D: Consensus review of the clinical utility of DNA cytometry in carcinoma of the breast. Breast Cancer Res Treat 28: 55-59, 1993
6. Hedley DW, Friedlander MI, Taylor IW, Rugg CA, Musgrove EA: Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry. J Histochem Cytochcm 31: 1333-1335, 1983
7. Vindelov LL, Christensen IJ, Nissen NI: A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry 3: 323-327, 1983
8. Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53: 457-481, 1958
9. Mantel N: Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep 50: 163-170, 1966
10. Cox DR: Regression models and life tables. J R Stat Soc (B) 34: 187-220, 1972
11. UICC International Union Against Cancer. TNM classification of malignant tumors. Third Edition, Geneva, 1988
12. Kallioniemi O-P: Comparison of fresh and paraffin-embedded tissue as starting material for DNA flow cytometry and evaluation of intratumor heterogeneity. Cytometry 9: 164-169, 1988
13. Koss LG, Bogdan C, Herz F, Wersto RP: Flow cytometric measurements of DNA and other cell components in human tumors: a critical appraisal. Human Pathol 20: 528-548, 1989
14. Frierson HF Jr: The need for improvement in flow cytometric analysis of ploidy and S-phase fraction. Am J Clin Pathol 95:439-441, 1991
15. Fisher B, Gunduz N, Costantino J, Fisher ER, Redmond C, Mamounas EP, Siderits R: DNA flow cytometric analysis of primary operable breast cancer. Cancer 68: 465-475, 1991
16. Clark GM, Dressler LG, Owens MA, Pounds G, Oldaker T, McGuire WL: Prediction of relapse or survival in patients with node-negative breast cancer by DNA flow cytometry. N Engl J Med 320: 627-633, 1989
17. Sigurdsson H, Baldetorp B, Borg A, Dalberg M, Ferno M, Killander D, Olsson H: Indicators of prognosis in node-negative breast cancer. N Engl J Med 322: 1045-1053, 1990
18. Weaver DL, Bagwell CB, Hitchcox SA, Whetstone SD, Baker DR, Herbert DJ, Jones MA: Improved flow cytometric determination of proliferative activity (S-phase fraction) from paraffin-embedded tissue. Am J Clin Pathol 94: 576-584, 1990
19. Dowle CS, Owainati A, Robins A, Burns K, Ellis IO, Elston CW, Blamey RW: Prognostic significance of the DNA conlent of human breast cancer. Br J Surg 74: 133-136, 1987
20. Dressler LG, Seamer LC, Owens MA, Clark GM, McGuire WL: DNA flow cytometry and prognostic factors in 1331 frozen breast cancer specimens. Cancer 61: 420-427, 1988
21. Furh JE, Frye A, Kattine AA, Van Metter S: Flow cytometric determination of breast tumor heterogeneity. Cancer 67: 1401-1405, 1991
22. Joensuu H, Kallioniemi O-P: Different opinions on classification of DNA histograms produced from paraffin-embedded tissue. Cytometry 10: 711-717, 1989
23. Kallioniemi O-P, Joensuu H, Klemi P, Koivula T: Inter-laboratory comparison of DNA flow cytometric results from paraffin-embedded breast carcinomas. Breast Cancer Res Treat 17:59-61, 1990
24. Koss LG, Wersto RP, Simmons DA, Deitch D, Hertz F, Freed S: Predictive value of DNA measurements in bladder washings. Comparison of flow cytometry, image cytophotometry, and cytology in patients with a past history of urothelial tumors. Cancer 64: 916-924, 1989
25. Baldetorp B, Ferno M, Falienius A, Fallenius-Vecchi G, Idvall I, Olsson H, Sigurdsson H, Akerman M, Killander D: Image cytometric DNA analysis in human breast cancer analysis may add prognostic information in diploid cases with low S-phase fraction by flow cytometry. Cytometry 13: 577-585, 1992
26. Hedley DW, Rugg CA, Gelber RD: Association of DNA index and S-phase fraction with prognosis of node positive early breast cancer. Cancer Res 47: 4729-4735, 1987
27. Lewis WE: Prognostic significance of flow cytometric DNA analysis in node-negative breast cancer patients. Cancer 65: 2315-2320, 1990
28. Thorud E, Fossa SD, Vaage S, Kaalhus O, Knudsen OS, Bormer O, Shoaib MC: Primary breast cancer. Flow cytometric DNA pattern in relation to clinical and histopathologic characteristics. Cancer 57: 808-811, 1986
29. Beerman H, Kluin M, Van de Velde CJH, Hermans J, Cornelisse CJ: DNA flow cytometry in the prognosis of node-negative breast cancer. N Engl J Med 321: 473-474, 1989
30. Keyhani-Rofagha S, O'Toole RV, Farrar WB, Sickle-Santanello B, DeCenzo J, Young D: Is DNA ploidy an independent prognostic indicator in infiltrative node-negative breast adenocarcinoma? Cancer 65: 1577-1582, 1990
31. Muss HB, Kute TE, Case LD, Smith LR, Booher C, Long R, Kammire L, Gregory B, Brockschmidt JK: The relation of flow cytometry to clinical and biologic characteristics in women with node negative primary breast cancer. Cancer 64:1894-1900, 1989
32. Noguchi M, Taniya T, Ohta N, Koyasaki N, Miyasaki I, Mizukami Y: Lymph node metastases versus DNA ploidy as prognostic factors for invasive ductal carcinoma of the breast. Breast Cancer Res Treat 19: 23-31, 1991
33. Sharma S, Mishra MC, Kapur BML, Verma K, Nath I: The prognostic significance of ploidy analysis in operable breast cancer. Cancer 68: 2612-2616, 1991
34. Hedley DW: Developments in the use of flow cytometry as a guide to the prognosis of cancer. Diagn Oncol 1: 2-4, 1991
35. O'Reilly SM, Camplejohn RS, Barnes DM, Millis RR, Rubens RD, Richards MA: Node-negative breast cancer: Prognostic subgroups defined by tumor size and flow cytometry. J Clin Oncol 8: 2040-2046, 1990
36. Clark GM, Mathieu M-C, Owens MA, Dressler LG, Eudey L, Tormey DC, Osborne CK, Gilchrist KW, Mansour EG, Abeloff MD, McGuire WL: Prognostic significance of S-phase fraction in good risk, node-negative breast cancer patients. J Clin Oncol 10: 428-432, 1992
37. Ewers S-B, Attewell R, Baldetorp B, Borg A, Langstrom E, Killander D: Prognostic potential of flow cytometric S-phase and ploidy prospectively determined in primary-breast carcinomas. Breast Cancer Res Treat 20: 93-108, 1991