Effect of colchicine on intracellular transport of alkaline phosphatase is primary culture of adult rat hepatocytes - Immunocytochemical study

Acta Histochemica et Cytochemica

Volumn 29, Issue 1, 1996, Pages 45-49

  Chida, Kohsuke ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Alkaline phosphatase; Colchicine; Intracellular transport; Primary culture; Rat hepatocyte

Indexed keywords

EID: 0029915534     PISSN: 00445991     EISSN: None     Source Type: Journal    
DOI: 10.1267/ahc.29.45     Document Type: Article

References (10)

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2. Chida, K.: Immunohistochemical detection of alkaline phosphatase in formalin-fixed and paraffin-embedded rat organs by means of avidin-biotin peroxidase complex method. Okajimas Folia Anat. Jpn. 70; 203-208, 1993.
3. Durand-Schneider, A. -M., Bouanga, J. -C., Feldmann, G. and Maurince, M.: Microtubule disruption interferes with the structural and functional integrity of the apical pole in primary cultures of rat hepatocytes. Eur. J. Cell Biol. 56; 260-268, 1991.
4. Hatoff, D. E. and Hardison, W. G. M.: Induced synthesis of alkaline phosphatase by bile acids in rat liver cell culture. Gastroenterology 77; 1062-1067, 1979.
5. Ikehara, Y., Mansho, K. and Kato, K.: Inducible effect of colchicine on alkaline phosphatase in rat liver in vivo. J. Biochem. 84; 1335-1338, 1978.
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8. Misumi, Y., Oda, K. and Ikehara, Y.: Induction of alkaline phosphatase and its transport to cell surface in primary culture of rat hepatocyres: Effect of the antimicrotubular agent colchicine. J. Biochem. 100; 433-438, 1986.
9. Oda, K. and Ikehara, Y.: Inhibitory effect of colchicine on translocation of alkaline phosphatase to the plasma membrane concomitant to its induction in rat liver. Biochim. Biophys. Acta 640; 398-408, 1981.
10. Seglen, P. O.: Preparation of isolated rat liver cell. Methods Cell Biol. 13; 29-83, 1976.