Acute Na+,K+-ATPase Inhibition with Bufalin Impairs Pressure Natriuresis in the Rat

Hypertension

Volumn 27, Issue 3 II, 1996, Pages 668-671

  Patel, Ami R ^a   Kurashina, Toshiaki ^b   Granger, Joey P ^b   Kirchner, Kent A ^b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b NONE

Author keywords

Bufanolides; Homeostasis; Na+,K+ transporting ATPase; Natriuresis

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BUFALIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; AUTOREGULATION; BLOOD PRESSURE REGULATION; CONFERENCE PAPER; CONTROLLED STUDY; HOMEOSTASIS; HYPERTENSION; KIDNEY BLOOD FLOW; MALE; NATRIURESIS; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BLOOD PRESSURE; BUFANOLIDES; GLOMERULAR FILTRATION RATE; HYPERTENSION; MALE; NA(+)-K(+)-EXCHANGING ATPASE; NATRIURESIS; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW;

EID: 0029915362     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.hyp.27.3.668     Document Type: Article

References (23)

1. Yuan CM, Manunta P, Hamlyn JM, Chen S, Bohen E, Yeun J, Haddy JF, Pamnani MB. Long-term ouabain administration produces hypertension in rats. Hypertension. 1993;22:178-187.
2. Eliades D, Swindall B, Johnston J, Pamnani M, Haddy F. Hemodynamic effects of bufalin in the anesthetized dog. Hypertension. 1989;13:690-695.
3. Pamnani MB, Chen S, Bryant HJ, Schoolry JF Jr, Eliades DC, Yuan CM, Haddy FJ. Effects of three sodium-potassium adenosine triphosphatase inhibitors. Hypertension. 1991;18:316-324.
4. Pamnani MB, Chen S, Yuan CM, Haddy FJ. Chronic blood pressure effects of bufalin, a sodium-potassium ATPase inhibitor, in rats. Hypertension. 1994;23(suppl I):I-106-I-109.
5. Hamlyn JM, Blaustein MP, Bova S, Ducharme DW, Harris DW, Mandel F, Mathews WR, Ludens JH. Identification and characterization of a ouabain-like compound from human plasma. Proc Natl Acad Sci U S A. 1991;88:6259-6263.
6. +) ATPase associated with essential hypertension. Nature. 1982;300: 650-652.
7. DeWardener HE, MacGregor GA. Dahl's hypothesis that a saluretic substance may be responsible for a sustained rise in arterial pressure: its possible role in essential hypertension. Kidney Int. 1980;18:1-9.
8. Woolfson RG, Graves J, LaBella FS, Templeton JF, Poston L. Effect of bufalin and pregnanes on vasoreactivity of human resistance arteries. Biochem Biophys Res Commun. 1992;186:1-7.
9. Poston L, Woolfson RG. Effect of ouabain on endothelium-dependent relaxation of human resistance arteries. Hypertension. 1991;17:619-625.
10. Eliades D, Pamnani MB, Swindall BT, Haddy FJ. Effects of bufalin on renal venous outflow urine flow and natriuresis in the anesthetized dog. In: Cox RH, ed. Cellular and Molecular Mechanisms in Hypertension. New York, NY: Plenum Press; 1991:205-210.
11. +-ATPase inhibitors on cardiorenal function in the dog and rat. Hypertension. 1991; 17:438-439. Abstract.
12. Yates NA, McDougall JG. Effects of direct renal arterial infusion of bufalin and ouabain in conscious sheep. Br J Pharmacol. 1993;108: 627-630.
13. Guyton AC, Hall JE, Jackson TE. The basic kidney blood volume-pressure regulatory system: the pressure diuresis and natriuresis phenomena. In: Guyton AC, ed. Arterial Pressure and Hypertension. Philadelphia, Pa: WB Saunders Co; 1980:87-99.
14. Hall JE, Mizelle HL, Hildebrandt DA, Brands MW. Abnormal pressure natriuresis: a cause or a consequence of hypertension? Hypertension. 1990;15:547-559.
15. Hall JE, Granger JP, Hester RL, Montani JP. Mechanisms of sodium balance in hypertension: role of pressure-natriuresis. J Hypertens. 1986;4(suppl 4):S57-S65.
16. Patel A, Layne S, Watts D, Kirchner KA. L-Arginine administration normalizes pressure natriuresis in hypertensive Dahl rats. Hypertension. 1993;22:863-869.
17. Sample SJG, de Wardener HE. Effect of increased renal venous pressure on circulatory 'auto-regulation' of isolated dog kidneys. Circ Res. 1959;7:643-648.
18. Brownlee AA, Lee G, Mills IH. Marked inhibition of canine renal Na/K ATPase bifabufodienolide, but weak natriuretic activity in the rat. J Physiol. 1987;390:94P. Abstract.
19. +-ATPase activity. FASEB J. 1993;7:A548. Abstract.
20. Woolfson RG, Poston L. Effect of ouabain on endothelium-dependent relaxation of human resistance arteries. Hypertension. 1991;17:619-625.
21. Woolfson RG, Graves J, LaBella FS, Templeton JF, Poston L. Effect of bufalin and pregnancies on vasoreactivity of human resistance arteries. Biochem Biophys Res Commun. 1992;186:1-7.
22. Tamaki T, Fukui K, Fujioka S, Iwao H, Okahara T, Abe Y. Effects of ouabain on autoregulation of renal blood flow in dogs. Am J Physiol. 1986;250:F109-F114.
23. Huang BS, Huang X, Harmsen E, Leenen FHH. Chronic central versus peripheral ouabain, blood pressure, and sympathetic activity in rats. Hypertension. 1994;23(pt 2):1087-1090.