Formation of N-substituted 2-iminothiolanes when amino groups in proteins and peptides are modified by 2-iminothiolane

Analytical Biochemistry

Volumn 236, Issue 1, 1996, Pages 114-125

  Singh, Rajeeva ^a,b   Kats, Lana ^a   Blättler, Walter A ^a   Lambert, John M ^a  

^a IMMUNOGEN INC   (United States)

^b INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDES; AMINES; AMINO ACIDS; AMMONIA; DECAY (ORGANIC); MASS SPECTROMETRY; PEPTIDES; SULFUR COMPOUNDS;

2-IMINOTHIOLANE; AMIDE FUNCTIONALITIES; BENZYLAMINES; BIOCONJUGATES; DISULFIDE GROUPS; FIRST-ORDER PROCESS; LYSINE RESIDUES; THIOL ADDUCT;

SUBSTITUTION REACTIONS;

AMINE; IMINOTHIOL; PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL REACTION; MASS SPECTROMETRY; PKA; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0029914595     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.1996.0139     Document Type: Article

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