Duodenal active calcium transport in female rats increases with serum calcitriol concentrations, but reaches a plateau far below maximal calcitriol levels

Journal of Bone and Mineral Research

Volumn 11, Issue 11, 1996, Pages 1640-1645

  Boass, Agna ^a   Toverud, Svein U ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; CALCIUM ION;

ACTIVE TRANSPORT; ANIMAL EXPERIMENT; ARTICLE; CALCIUM ABSORPTION; CONTROLLED STUDY; DUODENUM; NEWBORN; NONHUMAN; RAT; VITAMIN BLOOD LEVEL;

EID: 0029914148     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbmr.5650111107     Document Type: Article

References (38)

1. 3 metabolites. Am J Physiol 233:E488-E494.
2. 3 in intestinal mucosa of rats. Metab Bone Dis Rel Res 1:29-33.
3. Halloran BP, DeLuca HF 1980 Calcium transport in small intestine during early development: role of vitamin D. Am J Physiol 239:G473-G479.
4. 3 on duodenal calcium absorption in vivo during early development. Am J Physiol 264:G528-G534.
5. 3 during neonatal development in the rat. J Biol Chem 256:7338-7342.
6. 3 concentration by calcium intake in rat pups. Bone Miner 1:193-203.
7. Halloran BP, Barthell EN, DeLuca HF 1979 Vitamin D metabolism during pregnancy and lactation in the rat. Proc Natl Acad Sci USA 76:5549-5553.
8. Pike JW, Parker JB, Haussler MR, Boass A, Toverud SU 1979 Dynamic changes in circulating 1,25-dihydroxyvitamin D during reproduction in rats. Science 204:1427-1429.
9. Halloran BP, DeLuca HF 1980 Calcium transport in small intestine during pregnancy and lactation. Am J Physiol 239:E64-E68.
10. Bruns ME, Boass A, Toverud SU 1987 Regulation by dietary calcium of vitamin D-dependent calcium-binding protein and active calcium transport in the small intestine of lactating rats. Endocrinology 121:278-283.
11. Quan-Sheng D, Miller SC 1989 Calciotrophic hormone levels and calcium absorption during pregnancy in rats. Am J Physiol 257:E118-E123.
12. Boass A, Lovdal JA, Toverud SU 1992 Pregnancy- and lactation-induced changes in active intestinal calcium transport in rats. Am J Physiol 263:G127-G134.
13. Boass A, Toverud SU 1995 Suppression of circulating calcitriol and duodenal active Ca transport by ketoconazole in pregnant rats. Am J Physiol 269:E934-E939.
14. Johnson JA, Kumar R 1994 Renal and intestinal calcium transport: roles of vitamin D and vitamin D-dependent calcium binding proteins. Sem Nephrol 14:119-128.
15. Holick MF 1995 Vitamin D: photobiology, metabolism, and clinical applications. In: DeGroot LJ, Besser M, Burger HG, Jameson JL, Loriaux DL, Marshall JC, Odell WD, Potts JT Jr, Rubenstein AH (eds.) Endocrinology, 3rd Ed, Vol 2. Saunders, Philadelphia, PA, U.S.A., pp. 990-1014.
16. Reinhardt TA, Horst RL, Goff JP 1993 1,25-dihydroxyvitamin D receptor occupancy is limited: Dissociation of occupied receptor levels from plasma 1,25-dihydroxyvitamin D levels. Endocrine J 1:317-322.
17. Boass A, Ramp WK, Toverud SU 1981 Hypocalcemic, hypophosphatemic rickets in rat pups suckling vitamin D-deprived mothers. Endocrinology 109:505-512.
18. Gran FC 1960 Studies on calcium and strontium-90 metabolism in rats. Acta Physiol Scand 48 (Suppl 167):3-109.
19. Schachter D, Dowdle EB, Schenker H 1960 Active transport of calcium by the small intestine of rat. Am J Physiol 198:263-268.
20. Boass A, Toverud SU, Pike JW, Haussler MR 1981 Calcium metabolism during lactation: enhanced intestinal calcium absorption in vitamin D-deprived hypocalcemic rats. Endocrinology 109:900-907.
21. Reinhardt TA, Horst RL, Orf JW, Hollis BW 1984 A microassay for 1,25-dihydroxyvitamin D not requiring high performance liquid chromatography: application to clinical studies. J Clin Endocrinol Metab 58:91-98.
22. 2D in rats. Am J Physiol 262:E840-E844.
23. Armbrecht HJ 1986 Age-related changes in calcium and phosphorus uptake by rat small intestine. Biochim Biophys Acta 882:281-286.
24. Fisher RB, Parsons DS 1950 The gradient of mucosal surface area in the small intestine of the rat. J Anat 84:272-282.
25. 9K mRNA and protein: Is there a correlation with intestinal calcium transport? J Bone Miner Res 8:1483-1490.
26. Pansu D, Bellaton C, Bronner F 1983 Developmental changes in the mechanisms of duodenal calcium transport in the rat. Am J Physiol 244:G20-G26.
27. Favus MJ, Mangelsdorf DJ, Tembe V, Coe BJ, Haussler MR 1988 Evidence for in vivo upregulation of the intestinal vitamin D receptor during dietary calcium restriction in the rat. J Clin Invest 82:218-224.
28. 2D, induced by dietary calcium restriction, on vitamin D receptors. Endocrinology 126:1031-1035.
29. Li X-Q, Tembe V, Horwitz GM, Bushinsky DA, Favus MJ 1993 Increased intestinal vitamin D receptor in genetic hypercalciuric rats: A cause of intestinal calcium hyperabsorption. J Clin Invest 91:661-667.
30. Barger-Lux MJ, Heaney RP, Lanspa SJ, Healy JC, DeLuca HF 1995 An investigation of sources of variation in calcium absorption efficiency. J Clin Endocrinol Metab 80:406-411.
31. 2-vitamin D concentrations and net intestinal calcium, phosphate, and magnesium absorption in humans. Am J Clin Nutr 32:2052-2060.
32. Gallagher JC, Riggs BL, Eisman J, Hamstra A, Arnaud SB, DeLuca HF 1979 Intestinal calcium absorption and serum vitamin D metabolites in normal subjects and osteoporotic patients. J Clin Invest 64:729-736.
33. 2-vitamin D concentrations in healthy men. Kidney Int 24:555-560.
34. 2-vitamin D concentrations as determinants of calcium balance in healthy men. Kidney Int 26:752-759.
35. Hino M, Yamamoto I, Shigeno C, Aoki J, Dokoh S, Fukunaga M, Morita R, Torizuka K 1986 Evidence that factors other than 1,25 dihydroxyvitamin D may play a role in augmenting intestinal calcium absorption in patients with primary hyperparathyroidism. Calcif Tissue Int 38:193-196.
36. Sheikh MS, Ramirez A, Emmett M, Santa Ana C, Schiller LR, Fordtran JS 1988 Role of vitamin D-dependent and vitamin D-independent mechanisms in absorption of food calcium. J Clin Invest 81:126-132.
37. 3 and intestinal vitamin D receptor concentrations in normal women. J Clin Endocrinol Metab 75:176-182.
38. Specker BL, Vieira NE, O'Brien KO, Ho ML, Heubi JE, Abrams SA, Yergey AL 1994 Calcium kinetics in lactating women with low and high calcium intakes. Am J Clin Nutr 59:593-599.