Control of nasal dilator muscle activities during exercise: Role of nasopharyngeal afferents

Journal of Applied Physiology

Volumn 80, Issue 5, 1996, Pages 1520-1527

  Sullivan, Jenna ^a   Fuller, David ^a   Fregosi, Ralph F ^a,b  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

carbon dioxide rebreathing; control of breathing; facial motoneurons; lidocaine; nasal splints

Indexed keywords

CARBON DIOXIDE; HELIUM; LIDOCAINE; OXYGEN;

ADULT; AIRWAY RESISTANCE; ARTICLE; CARBON DIOXIDE BREATHING; CLINICAL PROTOCOL; CONTROLLED STUDY; ELECTROMYOGRAPHY; EXERCISE; FEMALE; HELIUM OXYGEN BREATHING; HUMAN; HUMAN EXPERIMENT; HYPERCAPNIA; LUNG VENTILATION; MALE; MOTONEURON; NASOPHARYNX; NORMAL HUMAN; NOSE BREATHING; PRIORITY JOURNAL; RESPIRATION CONTROL;

EID: 0029913739     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1996.80.5.1520     Document Type: Article

References (20)

1. Bartlett, D., Jr. Upper airway motor systems. In: Handbook of Physiology. The Respiratory System. Control of Breathing. Bethesda, MD: Am. Physiol. Soc., 1986, sect. 3, vol. II, pt. 1, chapt. 8, p. 223-245.
2. Connel, D. C., and R. F. Fregosi. Influence of nasal airflow and resistance on nasal dilator muscle activity during exercise. J. Appl. Physiol. 74: 2529-2536, 1993.
3. Dempsey, J. A., L. Adams, D. M. Ainsworth, R. F. Fregosi, C. C. Gallagher, A. Guz, B. D. Johnson, and S. K. Powers. Airway, lung, and respiratory muscle function during exercise. In: Handbook of Physiology. Exercise: Regulation and Integration of Multiple Systems. Bethesda, MD: Am. Physiol. Soc. In press.
4. Fregosi, R. F., and R. L. Lansing. Neural drive to nasal dilator muscles: influence of exercise intensity and oronasal flow partitioning. J. Appl. Physiol. 79: 1330-1337, 1995.
5. Fuller, D., J. Sullivan, B. Essif, K. Personius, and R. F. Fregosi. Measurement of the EMG-force relationship in a human upper airway muscle. J. Appl. Physiol. 79: 270-278, 1995.
6. Horner, R. L., J. A. Innes, H. B. Holden, and A. Guz. Afferent pathway(s) for pharyngeal dilator reflex to negative pressure in man: a study using upper airway anesthesia. J. Physiol. Lond. 436: 31-44, 1991.
7. Horner, R. L., J. A. Innes, K. Murphy, and A. Guz. Evidence for reflex upper airway dilator muscle activation by sudden negative airway pressure in man. J. Physiol. Lond. 436: 15-29, 1991.
8. Hussain, S. N. A., R. L. Pardy, and J. A. Dempsey. Mechanical impedance as determinant of inspiratory neural drive during exercise in humans. J. Appl. Physiol. 59: 365-375, 1985.
9. Jacobs, B. L., C. W. Metzler, C. A. Fornal, and S. C. Veasey. Response profiles of serotonergic neurons to motor challenges differ for pontine and medullary raphe neurons. Soc. Neurosci. Abstr. 20: 378, 1994.
10. Jones, A. S., J. M. Lancer, G. Shone, and J. C. Stevens. The effect of lignocaine on nasal resistance and nasal sensation of airflow. Acta Otolaryngol. 101: 328-330, 1986.
11. Kay, A., J. Trinder, G. Bowes, and Y. Kim. Changes in airway resistance during sleep onset. J. Appl. Physiol. 76: 1600-1607, 1994.
12. Krogh, A., and J. Lindhard. The regulation of respiration and circulation during the initial stages of muscular work. J. Physiol. Lond. 47: 112-136, 1913.
13. Mezzanotte, W. S., D. J. Tangel, and D. P. White. Mechanisms of control of alae nasi muscle activation. J. Appl. Physiol. 72: 925-933, 1992.
14. Olson, L. G., and K. P. Strohl. The response of the nasal airway to exercise. Am. Rev. Respir. Dis. 135: 356-359, 1987.
15. Proctor, D. F. Form and function of the upper airways and larynx. In: Handbook of Physiology. The Respiratory System. Control of Breathing. Bethesda, MD: Am. Physiol. Soc., 1986, sect. 3, vol. III, pt. 1, chapt. 6, p. 63-73.
16. Tsubone, H. Nasal "pressure" receptors. Jpn J. Vet. Sci. 52: 225-232, 1990.
17. Vandermaelen, C. P., and G. K. Aghajanian. Serotonin-induced depolarization of rat facial motoneurons in vivo: comparisons with amino acid neurotransmitters. Brain Res. 239: 139-152, 1982.
18. Van Lunteren, E., W. B. Van de Graaff, D. M. Parker, J. Mitra, M. A. Haxhiu, K. P. Strohl, and N. S. Cherniack. Nasal and laryngeal reflex responses to negative upper airway pressure. J. Appl. Physiol. 56: 746-752, 1984.
19. Wheatley, J. R., T. C. Amis, and L. A. Engel. Influence of nasal airflow temperature and pressure on alae nasi electrical activity. J. Appl. Physiol. 71: 2283-2291, 1991.
20. Wheatley, J. R., W. S. Mezzanotte, D. J. Tangel, and D. P. White. Influence of sleep on genioglossus muscle activation by negative pressure in normal men. Am. Rev. Respir. Dis. 148: 597-605, 1993.