Modelling the kinetics of chromosome exchange formation in human cells exposed to ionising radiation

Radiation and Environmental Biophysics

Volumn 35, Issue 1, 1996, Pages 31-35

  Moiseenko, V V ^a,d   Edwards, A A ^b   Nikjoo, N ^c  

^a MMRC   (Russian Federation)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

^c MEDICAL RESEARCH COUNCIL   (United Kingdom)

^d MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME STRUCTURE; DNA STRAND BREAKAGE; HUMAN; HUMAN CELL; IONIZING RADIATION; RADIATION DOSE; RADIATION HAZARD; RADIATION INJURY;

ANIMALS; CHROMOSOME ABERRATIONS; DNA DAMAGE; GAMMA RAYS; HUMANS; KINETICS; LYMPHOCYTES; MODELS, GENETIC; MONTE CARLO METHOD; RADIATION INJURIES, EXPERIMENTAL;

EID: 0029913055     PISSN: 0301634X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01211240     Document Type: Article

References (12)

1. Lloyd DC, Edwards AA (1983) Chromosome aberrations in human lymphocytes: effects of radiation quality and dose rate. In: Radiation-induced chromosome damage in man. (T Ishihara, M S Sasaki (eds) Alan R. Liss, New York, pp 23-49
2. Vyas RC, Darroudi F, Natarajan AT (1991) Radiation-induced chromosomal breakage and rejoining in interphase-metaphase chromosomes of human lymphocytes. Mutat Res 249:29-35
3. Brown JM, Evans JW (1992) Fluorescence in situ hybridization: an improved method of quantitative chromosome damage and repair. Br J Radiol (Suppl) 24:61-64
4. Brown JM, Evans JW, Kovacs MS (1993) Mechanism of chromosome exchange formation in human fibroblasts: insight from "chromosome painting". Environ Mol Mutagen 22: 218-224
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9. Purrott RJ, Reeder E (1976) Chromosome aberration yields in human lymphocytes induced by fractionated doses of x-radiation. Mutat Res 34: 437-446
10. Schmid E, Bauchinger M. Mergenthaler W (1976) Analysis of the time relationship for the interaction of x-ray-induced primary breaks in the formation of dicentric chromosomes. Int J Radiat Biol 30: 339-346
11. Edwards AA, Lloyd DC, Prosser JS (1985) The induction of chromosome aberrations in human lymphocytes by accelerated charged particles. Radiat Prot Dosim 13: 205-209
12. Virsik RP, Blohm R, Hermann K-P, Modler H, Harder D (1983) Chromosome aberrations and the mechanism of primary lesion interaction. In: Radiation protection - microdosimetry. (J Booz, HG Ebert eds) EUR 8395 EN. Commission of the European Communities (CEC), Luxembourg, pp 409-422