Two regulated secretory pathways for newly synthesized parotid salivary proteins are distinguished by doses of secretagogues

Journal of Cell Science

Volumn 109, Issue 10, 1996, Pages 2591-2599

  Castle, J David ^a   Castle, Anna M ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

Acinar cell; Regulated secretion; Salivary protein

Indexed keywords

AMYLASE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; ISOPRENALINE; MUSCARINIC AGENT; PILOCARPINE; SALIVA PROTEIN; SECRETORY PROTEIN;

ACINAR CELL; ANIMAL TISSUE; ARTICLE; CELL SURFACE; CONTROLLED STUDY; EXOCYTOSIS; GOLGI COMPLEX; MALE; NONHUMAN; PAROTID GLAND; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SECRETION; PROTEIN SYNTHESIS; RAT;

AMYLASES; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FASTING; ISOPROTERENOL; MALE; MODELS, BIOLOGICAL; PAROTID GLAND; PILOCARPINE; RATS; RATS, SPRAGUE-DAWLEY; SALIVA; SALIVARY PROTEINS; TIME FACTORS;

ANIMALIA;

EID: 0029912792     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Anderson, L. C., Garrett, J. R., Johnson, D. A., Kauffman, D. L., Keller, P. J. and Thulin, A. (1984). Influence of circulating catecholamines on protein secretion into rat parotid saliva during parasympathetic stimulation. J. Physiol. 352, 163-171.
2. Arvan, P. and Castle, J. D. (1987). Phasic secretion of newly synthesized secretory proteins in the unstimulated rat exocrine pancreas. J. Cell Biol. 104, 243-252.
3. Arvan, P., Kuliawat, R., Prabakaran, D., Zavacki, A., Elahi, D., Wang, S. and Pilkey, D. (1991). Protein discharge from immature secretory granules displays both regulated and constitutive characteristics. J. Biol. Chem. 266, 14171-14174.
4. Arvan, P. and Castle, J. D. (1992). Protein sorting and secretion granule formation in regulated secretory cells. Trends Cell Biol. 2, 327-331.
5. Ball, W. D., Hand, A. R. and Johnson, A. O. (1988). Secretory proteins as markers of cellular phenotypes in rat salivary glands. Dev. Biol. 125, 265-279.
6. Baum, B. J. (1987). Regulation of salivary secretion. In The Salivary System (ed. L. M. Sreebny), pp. 123-134. CRC Press.
7. Bernfeld, P. (1955). Amylases α and β. Meth. Enzymol. 1, 149-158.
8. Brewer, C. B. and Roth, M. G. (1995). Polarized exocytosis in MDCJK cells is regulated by phosphorylation. J. Cell Sci. 108, 789-796.
9. Brignoni, M., Pignataro, O. P., Rodriguez, M. L., Alvarez, A., Vega-Salas, D. E., Rodriguez-Boulan, E. and Salas, P. J. I. (1995). Cyclic AMP modulates the rate of constitutive exocytosis of apical membrane proteins in Madin-Darby canine kidney cells. J. Cell Sci. 108, 1931-1943.
10. Brown, D. and Sabolic, I. (1993). Endosomal pathways for water channel and proton pump recycling in kidney epithelial cells. J. Cell Sci. Suppl. 17, 49-59.
11. Cameron, R. S., Cameron, P. L. and Castle, J. D. (1986). A common spectrum of polypeptides occurs in secretion granule membranes of different exocrine glands. J. Cell Biol. 103, 1299-1313.
12. Carnell, L. and Moore, H.-P. H. (1994). Transport via the regulated secretory pathway in semi-intact PC12 cells: Role of intra-cisternal calcium and pH in the transport and sorting of secretogranin II. J. Cell Biol. 127, 693-705.
13. Castle, A. M., Stahl, L. E. and Castle, J. D. (1992). A 13-amino acid N-terminal domain of a basic proline-rich protein is necessary for storage in secretory granules and facilitates exit from the endoplasmic reticulum. J. Biol. Chem. 267, 13093-13100.
14. DeCamilli, P. and Navone, F. (1987). Regulated secretory pathways of neurons and their relation to the regulated secretory pathway of endocrine cells. Ann. NY Acad. Sci. 493, 461-479.
15. DeLisle, R. and Bansal, R. (1996). Brefeldin A inhibits constitutive-like secretion of sulfated protein in pancreatic acinar cells. Eur. J. Cell Biol. (in press).
16. Emmelin, N. (1967). Nervous control of salivary glands. In Handbook of Physiology, section 6, The Alimentary Canal vol II. (ed. C. F. Code), pp. 595-632. Williams and Wilkins, Baltimore, MD.
17. 2+]) in single cells. Science 244, 1582-1585.
18. Girard, L., Castle, A., Hand, A., Castle, D. and Mirels, L. (1993). Characterization of common salivary protein 1, a product of rat submandibular, sublingual, and parotid glands. J. Biol. Chem. 268, 26592-26601.
19. Grimes, M. and Kelly, R. B. (1992). Intermediates in the constitutive and regulated secretory pathways release in vitro from semi-intact cells. J. Cell Biol. 117, 539-549.
20. James, D. E., Piper, R. C. and Slot, J. W. (1994). Insulin stimulation of GLUT-4 translocation: a model for regulated recycling. Trends Cell Biol. 4, 120-125.
21. Kuliawat, R. and Arvan, P. (1992). Protein targeting via the constitutive-like secretory pathway in isolated pancreatic islets: passive sorting in the immature granule compartment. J. Cell Biol. 118, 521-529.
22. Kuliawat, R. and Arvan, P. (1994). Distinct molecular mechanisms for protein sorting within immature secretory granules of pancreatic β-cells. J. Cell Biol. 126, 77-86.
23. Leslie, B. A. and Putney, J. W. (1983). Ionic mechanisms in secretagogue-induced morphological changes in rat parotid gland. J. Cell Biol. 97, 1119-1130.
24. Luini, A. and De Matteis, M. A. (1993). Receptor-mediated regulation of constitutive secretion. Trends Cell Biol. 3, 290-292.
25. Lundberg, J. M. and Hokfelt, T. (1983). Coexistence of peptides and classical neurotransmitters. Trends Neurosci. 6, 325-333.
26. Mirels, L. and Ball, W. D. (1992). Neonatal rat submandibular gland protein SMG-A and parotid secretory protein are alternatively regulated members of a salivary protein multigene family. J. Biol. Chem. 267, 2679-2687.
27. Milgram, S. L., Eipper, B. A. and Mains, R. E. (1994). Differential trafficking of soluble and integral membrane secretory granule-associated proteins. J. Cell Biol. 124, 33-41.
28. Nauntofte, B. (1992). Regulation of electrolyte and fluid secretion in salivary acinar cells. Am. J. Physiol. 263, G823-G837.
29. Pimplikar, S. and Simons, K. (1994). Activators of protein kinase A stimulate apical but not basolateral transport in epithelial Madin-Darby canine kidney cells. J. Biol. Chem. 269, 19054-19059.
30. Sharoni, Y., Eimerl, S. and Schramm, M. (1976). Secretion of old versus new exportable protein in rat parotid slices. J. Cell Biol. 71, 107-122.
31. Vugman, I. and Hand, A. R. (1995). Quantitative immunocytochemical study of secretory protein expression in parotid glands of rats chronically treated with isoproterenol. Microsc. Res. Tech. 31, 106-117.
32. Young, J. A., Cook, D. I., van Lennep, E. W. and Roberts, M. (1987). Secretion by the major salivary glands. In Physiology of the Gastrointestinal Tract (ed. L. R. Johnson), pp. 773-815. Raven Press, NY.
33. Zastrow, M. v. and Castle, J. D. (1987). Protein sorting among two distinct export pathways occurs from the content of maturing exocrine storage granules. J. Cell Biol. 105, 2675-2684.
34. Zastrow, M. v., Castle, A. M. and Castle, J. D. (1989). Ammonium chloride alters secretory protein sorting within the maturing exocrine storage compartment. J. Biol. Chem. 264, 6566-6571.