Immobilized anti-KIT monoclonal antibody induces ligand-independent dimerization and activation of steel factor receptor: Biologic similarity with membrane-bound form of steel factor rather than its soluble form

Blood

Volumn 87, Issue 6, 1996, Pages 2235-2243

  Kurosawa, Kazuyo ^b   Miyazawa, Keisuke ^a   Gotoh, Akihiko ^b   Katagiri, Tomoko ^b   Nishimaki, Jiroh ^b   Ashman, Leonie K ^b   Toyama, Keisuke ^b  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE; STEEL FACTOR;

ARTICLE; DIMERIZATION; ENZYME PHOSPHORYLATION; HEMATOPOIESIS; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE; GOATS; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKEMIA, MEGAKARYOCYTIC, ACUTE; LIGANDS; MEMBRANE PROTEINS; MICE; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS C-KIT; SOLUBILITY; STEM CELL FACTOR; TUMOR STEM CELLS;

EID: 0029912548     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.6.2235.bloodjournal8762235     Document Type: Article

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