A novel diterpenoid labdane from Sideritis javalambrensis inhibits eicosanoid generation from stimulated macrophages but enhances arachidonate release

Biochemical Pharmacology

Volumn 51, Issue 6, 1996, Pages 863-868

  Pang, Linhua ^a   De Las Heras, Beatriz ^a,b   Hoult, J R S ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

anti inflammatory drugs; cyclo oxygenase; diterpenoids; Lamiaceae; nitric oxide synthase; thimerosal; transacylation

Indexed keywords

1 ACYLGLYCEROPHOSPHOCHOLINE ACYLTRANSFERASE INHIBITOR; 8ALPHA HYDROXY LABDA 13 (16), 14 DIEN; ANTIINFLAMMATORY AGENT; ARACHIDONIC ACID; BACTERIUM LIPOPOLYSACCHARIDE; CALCIMYCIN; DITERPENOID; ICOSANOID; IONOPHORE; LABDANE; NEW DRUG; NITRIC OXIDE SYNTHASE; OLEIC ACID; PHORBOL 13 ACETATE 12 MYRISTATE; PLANT EXTRACT; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; RADIOISOTOPE; SIDERITIS JAVALAMBRENSIS EXTRACT; THIOMERSAL; UNCLASSIFIED DRUG; ZYMOSAN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG ISOLATION; DRUG MECHANISM; ICOSANOID METABOLISM; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

SIDERITIS JAVALAMBRENSIS;

EID: 0029912511     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(95)02249-X     Document Type: Article

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