An integrated method to determine epithelial transport and bioactivity of oral drug candidates in vitro

Pharmaceutical Research

Volumn 13, Issue 1, 1996, Pages 23-26

  Rubas, Werner ^a   Cromwell, Mary E M ^a   Mrsny, Randall J ^a   Ingle, Gladys ^a   Elias, Kathleen A ^a  

^a GENENTECH INC   (United States)

Author keywords

Bioassay; Caco 2; GHRP; Growth hormone; Intestinal metabolism; Intestinal transport; Pituitary

Indexed keywords

GROWTH HORMONE RELEASING FACTOR; HISTIDYL DEXTRO TRYPTOPHYLALANYLTRYPTOPHYL DEXTRO PHENYLALANYLLYSINAMIDE;

ANIMAL CELL; ARTICLE; BIOASSAY; CELL CULTURE; COLON CARCINOMA; DRUG ACTIVITY; DRUG METABOLISM; DRUG TRANSPORT; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYPOPHYSIS CELL; IN VITRO STUDY; INTESTINE ABSORPTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; BIOLOGICAL ASSAY; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EPITHELIUM; HORMONES; HUMANS; LINEAR MODELS; MOLECULAR WEIGHT; OLIGOPEPTIDES; SENSITIVITY AND SPECIFICITY;

EID: 0029912485     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016060729594     Document Type: Article

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