Possible reason for preferential damage to renal tubular epithelial cells evoked by amphotericin B

Antimicrobial Agents and Chemotherapy

Volumn 40, Issue 5, 1996, Pages 1116-1120

  Walev, Iwan ^a,b   Bhakdi, Sucharit ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b Inst of Med Microbiol and Hygiene   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B;

ANIMAL CELL; ARTICLE; CELL PH; CONTROLLED STUDY; DOSE RESPONSE; KIDNEY DISTAL TUBULE; MYCOSIS; NEPHROTOXICITY; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; RHESUS MONKEY; URINE ACIDIFICATION;

EID: 0029912433     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.5.1116     Document Type: Article

References (22)

1. Benson, J. M., and M. C. Nahata. 1988. Clinical use of systemic antifungal agents. Clin. Pharm. 7:424-438
2. Benson, J. M., and M. C. Nahata. 1989. Pharmacokinetics of amphotericin B in children. Antimicrob. Agents Chemother. 33:1989-1993.
3. Bhakdi, S., M. Muhly, S. Korom, and F. Hugo. 1989. Release of interleukin-1β associated with potent cytocidal action of staphylococcal alpha-toxin on human monocytes Infect. Immun. 57:3512-3519.
4. Bhakdi, S., U. Weller, I. Walev, E. Martin, D. Jonas, and M. Palmer. 1993 A guide to the use of pore-forming toxins for controlled permeabilization of cell membranes. Med. Microbiol. Immunol. 182:167-175.
5. Blum, S. F., S. B. Shohet, D. G. Nathan, and F. H. Gardner. 1969. The effect of amphotericin B on erythrocyte membrane cation permeability: its relation to in vivo erythrocyte survival. J. Lab. Clin. Med. 73:980-987.
6. Bolard, J. 1986 How do the polyene macrolide antibiotics affect the cellular membrane properties? Biochim. Biophys Acta 864:257-304.
7. Brajtburg, J., S. Elberg, J. Medoff, G. S. Kobayashi, D. Schlessinger, and G. Medoff. 1984. Stimulatory, permeabilizing, and toxic effects of amphotericin B on L cells. Antimicrob. Agents Chemother. 26:892-897.
8. Brajtburg, J., G. Medoff, G. S. Kobayashi, S. Elberg, and C. Finegold. 1980. Permeabilizing and hemolytic action of large and small polyene antibiotics on human erythrocytes. Antimicrob. Agents Chemother. 18:586-592.
9. Christiansen, K. J., E. M. Bernard, J. W. M. Gold, and D. Armstrong. 1985. Distribution and activity of amphotericin B in humans. J. Infect. Dis 152: 1037-1043.
10. Clements, J. S., Jr., and J. E. Peacock, Jr. 1990. Amphotericin B revisited: reassessment of toxicity. Am. J. Med. 88(5N):22N-27N.
11. Gouge, T. H., and V. T. Andriole. 1971 An experimental model of amphotericin B nephrotoxicity with renal tubular acidosis. J. Lab. Clin. Med 78: 713-724.
12. Hahn, G. M., and E. C. Shiu. 1983. Effect of pH and elevated temperatures on the cytotoxicity of some chemotherapeutic agents on chinese hamster cells in vitro. Cancer Res. 43:5789-5791.
13. Hoeprich, P. D. 1992. Clinical use of amphotericin B and derivatives. lore, mystique, and fact. Clin. Infect. Dis. 14:114-119.
14. Kaloyanides, G. J. 1994. Antibiotic-related nephrotoxicity. Nephrol. Dial. Transplant. 9:130-134.
15. Lampen, J. 1969. Amphotericin B and other polyenic antifungal antibiotics. Am. J. Clin. Pathol. 49:138-146.
16. Sabra, R., and R. A. Branch. 1990. Amphotericin B nephrotoxicity. Drug Saf. 5:94-108.
17. Shiabi, Z. K., B. L. Wasilauskas, and J. E. Peacock, Jr. 1988. Serum amphotericin B assay by scanning spectrophotometer. Ther. Drug Monit. 10: 486-489.
18. Steinmetz, P. R., and L. R. Lawson. 1970. Defect in urinary acidification induced in vitro by amphotericin B. J Clin. Invest. 49:5966-6001.
19. Trifillis, A. L., X. Cui, and G. L. Drusano. 1993. Use of human renal proximal tubule cell cultures for studying foscarnet-induced nephrotoxicity in vitro. Antimicrob. Agents Chemother. 37:2496-2499.
20. Walev, I., E. Martin, D. Jonas, M. Mohamadzadeh, W. Müller-Klieser, L. Kunz, and S. Bhakdi. 1994. Staphylococcal alpha-toxin kills human keratinocytes by permeabilizing the plasma membrane for monovalent ions. Infect. Immun. 61:4972-4979.
21. Walev, I., M. Palmer, E. Martin, D. Jonas, U. Weller, H. Höhn-Bentz, M. Husmann, and S. Bhakdi. 1994. Recovery of human fibroblasts from attack by the pore-forming α-toxin of Staphylococcus aureus. Microb. Pathog. 17: 187-201.
22. Wroblewski, F., and J. S. Ladue. 1955. Lactic dehydrogenase activity in blood Proc. Soc. Exp. Biol. Med. 90:210-213