Anti-DNA autoantibodies stimulate the release of interleukin-1 and interleukin-6 from endothelial cells

Journal of Pathology

Volumn 178, Issue 4, 1996, Pages 451-457

  Lai, Kar Neng ^a   Leung, Joseph C K ^a   Lai, K A Bik ^a   Li, Philip K T ^a   Lai, Christopher K W ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Anti DNA autoantibodies; Cytokines; Endothelial cells

Indexed keywords

AUTOANTIBODY; CYTOKINE; DNA ANTIBODY; IMMUNOGLOBULIN G; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6;

ADULT; AFFINITY CHROMATOGRAPHY; ARTICLE; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS;

ADULT; ANTIBODIES, ANTINUCLEAR; BASE SEQUENCE; CELL CULTURE TECHNIQUES; DNA; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; IMMUNOGLOBULIN G; INTERLEUKIN-1; INTERLEUKIN-6; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RECEPTORS, INTERLEUKIN-1; RNA, MESSENGER;

EID: 0029912208     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199604)178:4<451::AID-PATH499>3.0.CO;2-P     Document Type: Article

References (32)

1. Bendtzen K. Interleukin I, interleukin 6 and tumor necrosis factor in infection, inflammation and immunity Immunol Lett 1988, 19: 183-192.
2. Platanias LC, Vogelzang NJ. Interleukin-1. biology, pathophysiology, and clinical prospects Am J Med 1990; 89: 621-629.
3. Diarello CA. Interleukin-1 and interleukin-1 antagonism. Blood 1991; 77: 1627-1652.
4. Barnes PJ. Cytokines as mediators of chronic asthma. Am J Respir Crit Cure Med 1994; 150: 542-549.
5. Le J, Vilcek J Interleukin 6; a multifunctional cytokine regulating immune reactions and the acute phase protein response Lab Invest 1989; 61: 588-602
6. Tan EM, Cohen AS, Fries JF, et al The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25: 1271-1277
7. Lai KN, Leung JCK, Rifkin I, Lockwood CM. Effect of anti-neutrophil cytoplasm autoantibodies on the intracellular calcium concentration of human neutrophils. Lab Invest 1994; 70: 152-162.
8. Jaffe EA, Nachman EL, Becker CG, Minick CR. Culture of human endothelial cells derived from umbilical veins Identification by morphologic and immunologic criteria. J Clin Invest 1973; 52: 1745-1756.
9. Lai KN, Ho RT II, Leung JCK, Lai FM, Li PKT. Increased mRNA encoding for transforming growth factor-β in CD4+ cells from patients with IgA nephropathy. Kidney Int 1994; 46: 862-868
10. Westphal JR, Boerbooms AMT, Schalkwuk CJM, et al Anti-endothelial cell antibodies in sera of patients with autoimmune disease comparison betwen ELISA and FACS analysis. Clin Exp Inmunol 1994, 96: 444-449.
11. Hashimoto Y, Ziff M, Hurd ER. Increased endothelial cell adherence, aggregation, and Superoxide generation by neutrophils incubated in systemic lupus erythematosus and Felty's syndrome sera. Arthritis Rheumatol 1982; 25: 1409-1418
12. Yap HK, Ng SC, Lee B, et al Modulation of MHC expression on human endothelial cells by sera from patients with systemic lupus erythematosus. Clin Immunol Immunopathol 1993, 68: 321-326.
13. Lindsey NJ, Dawson RA, Henderson FJ, Greaves M, Hughes P. Stimulation of von Willebrand factor antigen release by immunoglobulin from thrombosis prone patients with systemic lupus erythematosus and antiphospholipid syndrome. Br J Rheumatol 1993; 32: 123-126
14. Yu L, Chang KL, Chiu CC, Chiang BN, Han SH, Wang SR Alteration of mitogenic responses of mononuclear cells by anti-ds DNA antibodies resembling immune disorders in patients with systemic lupus erythematosus. Stand J Rheumatol 1989; 18: 265-276
15. Tsai CY, Wu T, Sun K, Liao T, Lin W, Yu C. Polyclonal anti-dsDNA antibodies exert cytotoxic effect on cultured rat mesangial cells by binding to cell membrane and augmenting apoptosis. Stand J Rheumatol 1993; 22: 162-171.
16. Sironi M, Breviario F, Proserpio P, et al. IL-1 stimulated IL-6 production in endothehal cells. J Immunol 1989; 142: 549-553.
17. Linker-Israeli M, Deans RJ, Wallace DJ, Prehn J, Oxzeri-Chen T, Klmberg JR Elevated levels of endogenous IL-6 in systemic lupus erythematosus. J Immunol 1991, 147: 117-123.
18. Spronk PE, ter Borg EJ, Limburg PC, Kallenberg CGM. Plasma concentration of IL-6 in systemic lupus erythematosus: an indicator of disease activity. Clin Exp Immunol 1992; 90: 106-110.
19. Gabay C. Roux-Lombard P, de Moerloose P, Dayer JD, Vischer T, Guerne PA Absence of correlation between interleukin 6 and C-reactive protein blood levels in systemic lupus erythematosus compared with rheumatoid arthritis J Rheumatol 1993; 20: 815-821.
20. Metsarinne KP, Nordstrom CDE, Konttinen YT, Teppo AM, Fyhrquist FY. Plasma interleukin-6 and renin substrate in reactive arthritis, rheumatoid arthritis and systemic lupus erythematosus Rheumatol Int 1992; 12: 93-96
21. Gordon C, Richards N, Howie AJ, et al. Urinary IL-6, a marker for mesangial proliferative glomerulonephritis. Clin Exp Immunol 1991, 86: 145-149.
22. Horn Y, Iwano M, Hirata E, et al. Role of interleukin-6 in the progression of mesangial proliferative glomerulonephritis. Kidney Int 1993, 43 (Suppl 39): S71-S75.
23. Hirohata S, Miyamoto T Elevated levels of interleukin-6 in cerebrospinal fluid from patients with systemic lupus erythematosus and central nervous system involvement. Arthritis Rheum 1990, 33: 644-649.
24. Finck BK, Chan B, Wofsy D Interleukin 6 promotes murine lupus in NZb/NZW F1 mice. J Clin Invest 1994; 94: 585-591.
25. Gordon C, Emery E. Cytokines and the acute phase response in SLE Lupus 1993; 2: 345-347
26. Ketlinskii SA, Alekseeva TG. Perumov DN, Simbirtsev AS. The content of IL-1β in the blood serum of patients with systemic lupus erythematosus and rheumatoid arthritis. Ter Arkh (Russia) 1993; 65: 51-54.
27. Paleolog EM, Crossman DC, McVey JH, Pearson JD. Differential regulation by cytokines of constitutive and stimulated secretion of von Willebrand factor from endothelial cells Blood 1990; 75: 688-695.
28. Giddings JC, Shall L Enhanced release of von Willebrand factor by human endothelial cells in culture in the presence of phorbol myristate acetate and interleukin-1. Thromb Res 1987: 47: 259-267.
29. Suenage R, Evans M, Hatfield M. Abdou NI. Study of anti-DNA antibodies prepared by DNA-cellulose or Cibacron blue chromatography. J Immunol Methods 1986, 93: 131-140
30. Furie MB. McHugh DD. Migration of neutrophils across endothelial monolayers is stimulated by treatment of the monolayers with interleukin-1 or tumor necrosis factor-α J Immunol 1989; 143: 3309-3317.
31. Izui S, Lambert PH, Miescher PA. In vitro demonstration of a particular affinity of glomerular basement membrane and collagen for DNA. A possible basis for a local formation of DNA-anti-DNA complexes in systemic lupus erythematosus J Exp Med 1976; 144: 428-433.
32. Chan TM, Frampton G, Cameron JS Identification of DNA-binding proteins on human umbilical vein endothelial cell plasma membrane. Clin Exp Immunol 1993; 91: 110-114.