Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin

Biochemistry

Volumn 35, Issue 43, 1996, Pages 13808-13816

  Perin, Mark S ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALMODULIN; NEUREXIN; PROTEIN; RABPHILIN 3A; SYNAPTOTAGMIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN MEMBRANE; CARBOXY TERMINAL SEQUENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; RAT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; BRAIN; CALCIUM-BINDING PROTEINS; CALMODULIN; CHROMATOGRAPHY, AFFINITY; CLONING, MOLECULAR; CONSERVED SEQUENCE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GTP-BINDING PROTEINS; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PEPTIDE FRAGMENTS; RAB GTP-BINDING PROTEINS; RATS; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SYNAPTIC VESICLES; SYNAPTOTAGMIN I; SYNAPTOTAGMINS; VESICULAR TRANSPORT PROTEINS;

ANIMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 0029911966     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi960853x     Document Type: Article

References (36)

1. Artalejo, C. R., Henley, J., McNiven, M., & Palfrey, H. C. (1996) Calmodulin is the divalent cation receptor for rapid endocytosis, but not exocytosis, in chromaffin cells, Neuron 16, 195-205.
2. Bennett, M. K., Calakos, N., & Scheller, R. H. (1992) Syntaxin: a synaptic protein implicated in docking synaptic vesicles at presynaptic active zones, Science 257, 255-259.
3. Bennett, M. K., Miller, K. G., & Scheller, R. W. (1993) Casein kinase II phosphorylates the synaptic vesicle protein, p 65, J. Neurosci. 13, 1701-1707.
4. Bradford, M. M. (1976) A rapid and sensitive method for the quanlitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem. 72, 248-254.
5. Brose, N., Petrenko, A. G., Südhof, T. C., & Jahn, R. (1992) Synaptotagmin: a calcium sensor on the synaptic vesicle surface, Science 256, 1021-1025.
6. Davletov, B., Sontag, J.-M., Hata, Y., Petrenko, A. G., Fykse, E. M., Jahn, R., & Südhof, T. C. (1993) Phosphorylation of synaptotagmin I by casein kinase II, J. Biol. Chem. 268, 6816-6822.
7. Davletov, B. A., Krasnoperov, V., Hata, Y., Petrenko, A. G., & Südhof, T. C. (1995) High affinity binding of α-latrotoxin to recombinant neurexin 1a. J. Biol. Chem. 270, 23903-23905.
8. Dedman, J. R., Kaetzel, M. A., Chan, H. C., Nelson, D. J., & Jamieson, G. A. (1993) Selection of targeted biological modifiers from a bacteriophage library of random peptides, J. Biol. Chem. 268, 23025-23030.
9. DiAntonio, A., Parfitt, K. D., & Schwarz, T. L. (1993) Synaptic transmission persists in synaptotagmin mutants of Drosophila, Cell 73, 1281-1290.
10. Fournier, S., & Trifaro, J.-M. (1988) A similar calmodulin-binding protein expressed in chromaffin, synaptic and neurohypophyseal secretory vesicles, J. Neurochem. 50, 27-37.
11. Fukuda, M., Aruga, J., Niinobe, M., Aimoto, S., & Mikoshiba, K. (1994) Inositol 1,3,4,5-tetrakisphosphate binding to C2B domain of IP4BP/synaptotagmin II, J. Biol. Chem. 269, 29296-29211.
12. +2/calmodulin- and cAMP-dependent protein kinases in vitro, J. Neurosci. 15, 2385-2395.
13. +2 sensor for neurotransmitter release at a central synapse, Cell 79, 717-727.
14. Hata, Y., Davletov, B., Petrenko, A. G., Jahn, R., & Südhof, T. C. (1993) Interaction of synaptotagmin with the cytoplasmic domains of neurexins, Neuron 10, 307-315.
15. Hudson, A. W., & Birnbaum, M. J. (1995) Identification of a nonneuronal isoform of synaptotagmin, Proc. Natl. Acad. Sci. U.S.A. 92, 5895-5895.
16. Kato, M., Sasaki, T., Imazumi, K., Takahashi, K., Araki, K., Shiralaki, H., Matsuuma, Y., Ishida, H., Fujisawa, H., & Takai, Y. (1994) Biochem. Biophys. Res. Commun. 205, 1776-1784.
17. Kee, Y., & Scheller, R. H. (1996) Localization of synaptotagmin-binding domains on syntaxin, J. Neurosci. 16, 1975-1981.
18. +2:-dependent and -independent activities of neural and non-neural synaptotagmins, Nature 375, 594-599.
19. 2+-activated neurotransmitter release. Cell 74, 1125-1134.
20. Littleton, J. T., Stern, M., Perin, M. S., & Bellen, H. J. (1994) The calcium dependence of neurotransmitter release and the rate of spontaneous vesicle fusions are altered in synaptotagmin mutants, Proc. Natl. Acad. Sci. U.S.A. 91, 10888-10892.
21. Matteoli, M., Haimann, C., Torri-Tarelli, F., Polak, J. M., Ceccarelli, B., & De Camilli, P. (1988) Differential effect of α-latrotoxin on exocytosis from small synaptic vesicles and from large dense- core vesicles containing calcitonin gene-related peptide at the frog neuromuscular junction, Proc. Natl. Acad. Sci. U.S.A. 85, 7366-7370.
22. Means, A. R., VanBerkum, M. F., Bagchi, I., Lu, K. P., & Rasmussen, C. D. (1991) Regulatory functions of calmodulin, Pharmacol. Ther. 50, 255-270.
23. Nonet, M. L., Grundahl, K., Meyer, B. J., & Rand, J. B. (1993) Synaptic function is impaired but not eliminated in C. elegans mutants lacking synptotagmin. Cell 73, 1291-1305.
24. Perin, M. S. (1994) The C-terminus of synaptotagmin mediates interaction with the neurexins, J. Biol. Chem. 269, 8576-8581.
25. Perin, M. S., Fried, V. A., Mignery, G. A., Jahn, R., & Südhof, T. C. (1990) Phospholipid binding by a synaptic vesicle protein homologous to the regulatory domain of protein kinase C, Nature 345, 260-263.
26. Perin, M. S., Brose, N., Jahn, R., & Südhof, T. C. (1991) Domain structure of synaptotagmin (p65), J. Biol. Chem. 266, 623-629.
27. Petrenko, A. G., Perin, M. S., Davletov, B. A., Ushkaryov, Y. A., Geppert, M., & Südhof, T. C. (1991) Binding of synaptotagmin to α-lalrotoxin receptor implicates both in synaptic vesicle exocytosis. Nature 353, 65-68.
28. Shirataki, H., Kaibuchi, K., Sakoda, T., Kishida, S., Yamaguchi, T., Wada, K., Miyazaki, M., & Takai, Y. (1993) Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP- binding protein related to synaptotagmin, Mol. Cell. Biol. 13, 2061-2068.
29. Südhof, T. C. (1995) The synaptic vesicle cycle: a cascade of protein-protein interactions, Nature 375, 645-653.
30. 2 domains of synaptotagmin I, J. Biol. Chem. 271, 1262-1265.
31. +2/phospholipid-binding fold, Cell 80, 929-938.
32. Ullrich, B., Ushkaryov, Y. A., & Südhof, T. C. (1995) Cartography of neurexins: more than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons. Neuron 14, 497-507.
33. Ushkaryov, Y. A., Petrenko, A. G., Geppert, M., & Südhof, T. C. (1992) Neurexins: synaptic cell surface proteins related to the α-latrotoxin receptor and laminin, Science 257, 50-56.
34. Van Eldik, L. J., & Wolchok, S. R. (1984) Conditions for reproducible detection of calmodulin and S100β in immunoblots, Biochem. Biophys. Res. Commun. 124, 752-759.
35. Walch-Solimena, C., Blasi, J., Edelmann, L., Chapman, E. R., von Mollard, G. F., & Jahn, R. (1995) The t-SNAREs syntaxin 1 and SNAP-25 are present on organelles that participate in synaptic vesicle recycling, J. Cell Biol. 128, 637-645.
36. Zhang, J. Z., Davletov, B. A., Südhof, T. C., & Anderson, R. G. W. (1994) Synaptotagmin 1 is a high affinity receptor for clathrin AP-2: implications for membrane recycling, Cell 78, 751-760.