The Oct-1 POU-specific domain can stimulate small nuclear RNA gene transcription by stabilizing the basal transcription complex SNAPc

Molecular and Cellular Biology

Volumn 16, Issue 5, 1996, Pages 1955-1965

  Mittal, Vivek ^a,b   Cleary, Michele A ^b,c   Herr, Winship ^b   Hernandez, Nouria ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b Simons Center for Quantitative Biology   (United States)

^c STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SMALL NUCLEAR RIBONUCLEOPROTEIN; SMALL NUCLEAR RNA;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; DNA PROTEIN COMPLEX; GENE EXPRESSION REGULATION; HUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; TATA BOX; TRANSCRIPTION INITIATION;

AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; CLONING, MOLECULAR; CONSERVED SEQUENCE; DNA-BINDING PROTEINS; GENES, HOMEOBOX; GLUTATHIONE TRANSFERASE; HOMEODOMAIN PROTEINS; HOST CELL FACTOR C1; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OCTAMER TRANSCRIPTION FACTOR-1; OCTAMER TRANSCRIPTION FACTOR-2; OLIGONUCLEOTIDE PROBES; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; RNA POLYMERASE I; RNA POLYMERASE II; RNA, SMALL NUCLEAR; SEQUENCE HOMOLOGY, AMINO ACID; TATA BOX; TATA-BOX BINDING PROTEIN; TRANSCRIPTION FACTOR PIT-1; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0029911579     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.5.1955     Document Type: Article

References (54)

1. Assa-Munt, N., R. J. Mortishire-Smith, R. Aurora, W. Herr, and P. E. Wright. 1993. The solution structure of the Oct-1 POU-specific domain reveals a striking similarity to the bacteriophage lambda repressor DNA-binding domain. Cell 73:193-205.
2. Aurora, R., and W. Herr. 1992. Segments of the POU domain influence one another's DNA-binding specificity. Mol. Cell. Biol. 12:455-467.
3. Bark, C., P. Weller, J. Zabielski, L. Janson, and U. Pettersson. 1987 A distant enhancer is required for polymerase III transcription of a U6 RNA gene Nature (London) 328:356-359.
4. Carey, M. 1994. Simplifying the complex. Nature (London) 368:402-403.
5. Cleary, M. A., and W. Herr. 1995. Mechanisms for flexibility in DNA sequence recognition and VP16-induced complex formation by the Oct-1 POU domain. Mol Cell. Biol. 15:2090-2100.
6. Coenjaerts, F. E. J., J. A. W. M. van Oosterhout, and P. C. van de Vliet. 1994 The Oct-1 POU domain stimulates adenovirus replication by a direct interaction between the viral precursor terminal protein-DNA polymerase complex and the POU homeodomain. EMBO J. 13:5401-5408.
7. Das, G., C. S. Hinkley, and W. Herr. 1995. Basal promoter elements as a selective determinant of transcriptional activator function. Nature (London) 374:657-660.
8. Dekker, N., M. Cox, R. Boelens, C. Verrijzer, P. C. van der Vliet, and R. Kaptein. 1993. Solution structure of the POU-specific DNA-binding domain of Oct-1. Nature (London) 362:852-855.
9. Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
10. Gerster, T., and R. G. Roeder. 1988. A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins. Proc. Natl. Acad. Sci. USA 85:6347-6351.
11. Gstaiger, M., L. Knoepfel, O. Georgiev, W. Schaffner, and C. M. Hovens. 1995. A B-cell coactivator of octamer-binding transcription factors. Nature (London) 373:360-362.
12. Harlow, E., and D. Lane. 1988 Antibodies: a laboratory manual. Cold Spring Harbor laboratory Press, Cold Spring Harbor, N Y.
13. Henry, R. W., C. L. Sadowski, R. Kobayashi, and N. Hernandez. 1995. A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerases II and III Nature (London) 374:653-657.
14. Hernandez, N. 1992 Transcription of vertebrate snRNA genes and related genes. Cold Spring Harbor Monogr Ser. 22:281-313.
15. Herr, W., and M. A. Cleary. 1995. The POU domain: versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain. Genes Dev. 9:1679-1693.
16. Herr, W., R. A. Sturm, R. G. Clerc, L. M. Corcoran, D. Baltimore, P. A. Sharp, H. A. Ingraham, M. G. Rosenfeld, M. Finney, G. Ruvkun, and H. R. Horvitz. 1988. The POU domain: a large conserved region in the mammalian pit-2, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes Dev. 2:1513-1516.
17. Ingraham, H. A., S. E. Flynn, J. W. Voss, V. R. Albert, M. S. Kapiloff, L. Wilson, and M. G. Rosenfeld. 1990 The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions. Cell 61:1021-1033.
18. Kim, Y. J., S. Bjorklund, Y. Li, H. M. Sayre, and R. D. Komberg. 1994 A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77:599-608.
19. Klemm, J. D., M. A. Rould, R. Aurora, W. Herr, and C. O. Pabo. 1994. Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules. Cell 77:21-32.
20. Koleske, A. J., and R. A. Young. 1994. An RNA polymerase II holoenzyme responsive to activators. Nature (London) 368:466-469.
21. Koleske, A. J., and R. A. Young. 1995. The RNA polymerase II holoenzyme and its implications for gene regulation. Trends Biochem. Sci. 20:113-116.
22. Kristie, T. M., J. H. LeBowitz, and P. A. Sharp. 1989. The octamer-binding proteins form multi-protein-DNA complexes with the HSV α-TIF regulatory protein. EMBO J 8:4229-4238.
23. Kunkel, G. R., and T. Pederson. 1988 Upstream elements required for efficient transcription of a human U6 RNA gene resemble those of U1 and U2 genes even though a different polymerase is used. Genes Dev. 2:196-204.
24. Kunkel, T. A., J. D. Roberts, and R. A. Zakour. 1987 Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol. 154:367-382.
25. Lai, J.-S. 1993. The herpes simplex virus VP16-induced complex: transcriptional regulation through selective protein-protein association. Ph.D. thesis. State University of New York-Stony Brook, Stony Brook.
26. Lai, J.-S., M. A. Cleary, and W. Herr. 1992. A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain. Genes Dev. 6:2058-2065.
27. Lai, J.-S., and W. Herr. 1992. Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations. Proc. Natl. Acad Sci. USA 89:6958-6962.
28. LeBowitz, J. H., R. G. Clerc, M. Brenowitz, and P. A. Sharp. 1989. The Oct-2 protein binds cooperatively to adjacent octamer sites. Genes Dev 3:1625-1638.
29. Lobo, S., and N. Hernandez. 1989. A 7 bp mutation converts a human RNA polymerase II snRNA promoter into an RNA polymerase III promoter. Cell 58:55-67.
30. Lubo, S. M., and N. Hernandez. 1994. Transcription of snRNA genes by RNA polymerases II and III, p. 127-159. In R. C. Conaway and J. W. Conaway (ed.), Transcription, mechanisms and regulation. Raven Press, New York
31. Luo, Y., H. Fujii, T. Gerster, and R. G. Roeder. 1992. A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors. Cell 71:231-241.
32. Luo, Y., and R. G. Roeder. 1995. Cloning, functional characterization and mechanism of action of the B-cell-specific transcription coactivator OCA-B. Mol. Cell. Biol. 15:4115-4124.
33. Murphy, S., A. Pierani, C. Scheidereit, M. Melli, and R. G. Roeder. 1989. Purified octamer binding transcription factors stimulate RNA polymerase Ill-mediated transcription of the 7SK RNA gene. Cell 59:1071-3080.
34. Murphy, S., J.-B. Yoon, T. Gerster, and R. G. Roeder. 1992. Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence clement of small nuclear RNA genes. Mol. Cell. Biol. 12:3247-3261.
35. Ossipow, V., J.-P. Tassan, E. A. Nigg, and U. Schibler. 1995. A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation. Cell 83:137-146.
36. Pomerantz, J. L., T. M. Kristie, and P. A. Sharp. 1992. Recognition of the surface of a homeo domain protein. Genes Dev. 6:2047-2057.
37. Pomerantz, J. L., C. O. Pabo, and P. A. Sharp. 1995. Analysis of homeodomain function by structure-based desing of a transcription factor. Proc. Natl. Acad. Sci. USA 92:9752-9756.
38. Ptashne, M. 1988. How eucaryotic transcriptional activators work. Nature (London) 335:683-689
39. Reinagel, P., and N. Hernandez. Unpublished data
40. c) is required for RNA polymerase II and III snRNA gene transcription and interacts with TBP. Proc. Natl. Acad Sci. USA, in press.
41. Sadowski, C. L., R. W. Henry, S. M. Lobo, and N. Hernandez. 1993 Targeting TBP to a non-TATA box cis-regulatory element: a TBP-containing complex activates RNA polymerase II and III transcription from snRNA promoters through the PSE. Genes Dev. 7:1535-1548.
42. Stern, S., M. Tanaka, and W. Herr. 1989. The Oct-1 homeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16. Nature (London) 341:624-630.
43. Strubin, M., J. W. Newell, and P. Matthias. 1993. OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. Cell 80:497-506.
44. Studier, F. W., A. H. Rasenberg, J. J. Dunn, and J. W. Dubendorff. 1990. Use of T7 RNA polymerase to direct expression of cloned genes. Methods Enzymol. 185:60-89.
45. Tanaka, M., U. Grossniklaus, W. Herr, and N. Hernandez. 1988. Activation ofthe U2 snRNA promoter by the octamer motif defines a new class of RNA polymerase II enhancer elements Genes Dev. 2:1764-1778.
46. Tanaka, M., and W. Herr. 1990. Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylation. Cell 60:375-386
47. Tanaka, M., J.-S. Lai, and W. Herr. 1992. Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoter Cell 68:755-767.
48. Voss, J. W., L. Wilson, and M. G. Rosenfeld. 1991. POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promoter. Genes Dev. 5:1309-1320.
49. Waldschmidt, R., I. Wanandi, and K. H. Seifart. 1991 Identification of transcription factors required for the expression of mammalian U6 genes in vitro. EMBO J. 10:2595-2603.
50. Yoon, J.-B., S. Murphy, L. Bai, Z. Wang, and R. G. Roeder. 1995. Proximal sequence element-binding transcription factor (PTF) is a multisubunit complex required for transcription of both RNA polymerase II- and RNA polymerase III-dependent smalt nuclear RNA genes. Mol. Cell. Biol. 15:2019-2027.
51. Yoon, J.-B., and R. G. Roeder. 1996. Cloning of two proximal sequence element-binding transcription factor subunits (γ and δ) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein. Mol. Cell. Biol. 16:1-9.
52. Zoller, M. J., and M. Smith. 1983. Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors. Methods Enzymol. 100:468-500.
53. Zwilling, S., A. Annweiler, and T. Wirth. 1994. The POU domains of the Oct1 and Oct2 transcription factors mediate specific interaction with TBP Nucleic Acids Res. 22:1655-1662.
54. Zwilling, S., H. Konig, and T. Wirth. 1995. High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors. EMBO J. 14:1198-1208.