Inhibition of in vitro proliferation of chronic myelogenous leukemia progenitor cells by c-myb antisense oligodeoxynucleotides

Folia Histochemica et Cytobiologica

Volumn 34, Issue 3-4, 1996, Pages 129-134

  Szczylik, Cezary ^a   Skórski, Tomasz ^b   Malaguarnera, Lucia ^b   Hetman, Joanna ^a   Chen, Sing Tsung ^c   Calabretta, Bruno ^b  

^a MILITARY INSTITUTE OF MEDICINE   (Poland)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

blast crisis; c myb; CD34; chronic phase; CML; gene expression

Indexed keywords

CD34 ANTIGEN; OLIGODEOXYNUCLEOTIDE;

ARTICLE; CELL PROLIFERATION; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; COLONY FORMING CELL; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; ONCOGENE C MYB; STEM CELL;

EID: 0029911333     PISSN: 00155586     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Ahuja H, Bar-Eli N, Advani SH, Benchimol S, Cline MJ (1989) Alteration in the p53 gene and the clonal evolution of the blast crisis of chronic myelocytic leukemia. Proc Natl Acad Sci USA 86: 6783-6787
2. Anfossi G, Gewirtz AM, Calabretta B (1989) An oligomer complementary to c-myb encoded mRNA inhibits proliferation of human myeloid leukemia cell lines. Proc Natl Acad Sci USA 86: 3379-3383
3. Brandt J, Baird L, Lu L, Srour E, Hoffman R (1988) Characterization of a human hematopoietic progenitor cell capable of forming blast cell containing colonies in vitro. J Clin Invest 82: 1017-1027
4. Calabretta B, Sims RR, Valtieri M, Caracciolo P, Szczylik C, Venturelli D, Beran M, Gewirtz AM (1991) Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study with relevance to bone marrow purging. Proc Natl Acad Sci USA 88: 2351-2355
5. Calabretta B, Venturelli D, Kaczmarek L, Narni F, Talpaz M, Anderson B, Beran M, Baserga R (1986) Altered expression of G1 specific genes in human malignant myeloid cells. Proc Natl Acad Sci USA 83: 1495-1498
6. Caracciolo D, Venturelli D, Valtieri M, Peschle C, Gewirtz AM, Calabretta B (1990) Stage-related proliferative activity determines c-myb functional requirements during normal human hematopoiesis. J Clin Invest 85: 55-61
7. Churilla AM, Braciale TJ, Braciale VL (1989) Regulation of T-lymphocyte proliferation. Interleukin 2-mediated induction of c- myb gene expression is dependent on T-lymphocyte activation state. J Exp Med 170: 105-121
8. Civin CI, Strauss LC, Brovall C, Fackler MJ, Schwartz JF, Shaper JH (1984) A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-la cells. J Immunol 133: 157-165
9. Clarke MF, Kukowska-Lotallo JF, Westin EH, Smith M, Prochownick E (1988) Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation. Mol Cell Biol 8: 884-892
10. Craig RW, Bloch A (1984) Early decline in c-myb oncogene expression in the differentiation of human myeloblastic leukemia (ML-1) cells induced with 12-0-tetradecanoylphorbol-13-acetate. Cancer Res 44: 442-446
11. Feinstein E, Cimino G, Gale RP, Alimena G, Berthier R, Kishi K, Goldman J, Zaccaria A, Besebi A, Canaani E (1991) p53 in chronic myelogenous leukemia in acute phase. Proc Natl Acad Sci USA 88: 6923-6927
12. Ferrari S, Narni F, Mars W, Kaczmarek L, Venturelli D, Anderson B, Calabretta B (1986) Expression of growth regulated genes in human acute leukemias. Cancer Res 46: 5162-5166
13. Gewirtz AM, Calabretta B (1988) A c-myb antisense oligodeoxynucleotide inhibits normal human hematopoiesis in vitro. Science 242: 1303-1306
14. Kastan MB, Slamon DS, Civin CI (1989) Expression of protooncogene c-myb in normal human hematopoietic cells. Blood 73: 1444-1451
15. Koeffler PH, Golde DW (1981) Chronic myleogenous leukemia. New concepts. N Engl J Med 304: 1201-1209
16. Majello B, Kenyon LC, Dalla Pavera R (1986) Human c-myb proto-oncogene: nucleotide sequence of cDNA and organization of the genomic locus. Proc Natl Acad Sci USA 83: 96369640
17. Ness SA, Marknell A, Graf T (1989) The v-myb oncogene product binds to and activates the promyelocyte-specific mim-1 gene. Cell 59: 1115-1125
18. Ramsay RG, Ikeda K, Rifkind RA, Marks PA (1986) Changes in gene expression associated with induced differentiation of erythroleukemia, proto-oncogenes, globin genes and cell division. Proc Natl Acad Sci USA 84: 3171-3175
19. Rappelee DA, Mark D, Benda MJ, Werb Z (1988) Wound macrophages express TGF-α and other growth factors in vitro: analysis by mRNA phenotyping. Science 241: 708-172
20. Rovera G, Richard BA, Hudson S, Bittenbender S, Yamada M, Tourmay O, Preisler HD (1989) Point mutations in both transforming and nontransforming codons of the N-Ras proto-oncogene of Ph+ leukemias. Oncogene 4: 867-872
21. Rowley JD (1980) Ph+ positive leukemia, including chronic myelogenous leukemia. Clin Hematol ?: 55-86
22. Saiki RK, Gelfand DH, Staffel S, Scharf SS, Higuchi R, Horn GT, Mullils KB, Erlich HA (1988) Primer-directed enzymatic amplification of DNA with thermostable DNA polymerase. Science 230: 487-491
23. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: A laboratory manual; second edition. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
24. Suggs SV, Wallace RB, Hirose T, Kawashima BH, Itakura K (1981) Use of synthetic oligonucleotides as hybridization probes: isolation of cloned cDNA sequences for human β2-microglobulin. Proc Natl Acad Sci USA 78: 6613-6617
25. Valtieri M, Venturelli D, Pelosi E, Labbaye C, Mattia G, Fossati C, Gewirtz AM, Calabretta B, Peschle C (1991) Antisense myb inhibition of purified erythroid progenitors in development and differentiation is linked to cycling activity and expression of DNA polymerase A. Blood 77: 1181-1190
26. Westin EH, Gallo RC, Arya SK, Eva A, Souza LM, Baluda MA, Aaronson SA, Wong-Staal F (1982) Differential expression of the AMV gene in human hematopoietic cells. Proc Natl Acad Sci USA 79: 2194-2198