메뉴 건너뛰기




Volumn 6, Issue 4, 1996, Pages 467-480

Inherited neurodegenerative diseases and transgenic models

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; CONFERENCE PAPER; GENE MUTATION; HUMAN; NONHUMAN; TRANSGENIC ANIMAL;

EID: 0029910953     PISSN: 10156305     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1750-3639.1996.tb00876.x     Document Type: Conference Paper
Times cited : (7)

References (220)
  • 1
    • 0029612271 scopus 로고
    • Selective neurodegeneration in Huntington's disease
    • Albin RL (1995) Selective neurodegeneration in Huntington's disease. Ann Neurol 38:835-836
    • (1995) Ann Neurol , vol.38 , pp. 835-836
    • Albin, R.L.1
  • 2
    • 0029115555 scopus 로고
    • The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families
    • Alzheimer's Disease Collaborative Group (1995) The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families. Nature Genetics 11:219-222
    • (1995) Nature Genetics , vol.11 , pp. 219-222
  • 3
    • 0029976253 scopus 로고    scopus 로고
    • DNA damage and apoptosis in Alzheimer's disease. colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay
    • Anderson AJ, Su JH, Cotman CW (1996) DNA damage and apoptosis in Alzheimer's disease. colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay J Neurosci 16:1710-1719
    • (1996) J Neurosci , vol.16 , pp. 1710-1719
    • Anderson, A.J.1    Su, J.H.2    Cotman, C.W.3
  • 4
    • 0025717816 scopus 로고
    • The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease
    • Arnold SE, Hyman BT, Flory J, Damasio AR, Van Hoesen GW (1991) The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease. Cereb Cortex 1.103-116
    • (1991) Cereb Cortex , vol.1 , pp. 103-116
    • Arnold, S.E.1    Hyman, B.T.2    Flory, J.3    Damasio, A.R.4    Van Hoesen, G.W.5
  • 5
    • 0028878761 scopus 로고
    • N-methyl-D-aspartate receptors are critical for mediating the effects of glutamate on intracellular calcium concentration and immediate early gene expression in cultured hippocampal neurons
    • Bading H, Segal MM, Sucher NJ, Dudek H, Lipton SA, Greenberg ME (1995) N-methyl-D-aspartate receptors are critical for mediating the effects of glutamate on intracellular calcium concentration and immediate early gene expression in cultured hippocampal neurons. Neuroscience 64:653-664
    • (1995) Neuroscience , vol.64 , pp. 653-664
    • Bading, H.1    Segal, M.M.2    Sucher, N.J.3    Dudek, H.4    Lipton, S.A.5    Greenberg, M.E.6
  • 6
    • 0021967395 scopus 로고
    • Reduced numbers of somatostatin receptors in the cerebral cortex in Alzheimer's disease
    • Beal MF, Mazurek MF, Tran VT, Chattha G, Bird ED, Martin JB (1985) Reduced numbers of somatostatin receptors in the cerebral cortex in Alzheimer's disease. Science 229:289-291
    • (1985) Science , vol.229 , pp. 289-291
    • Beal, M.F.1    Mazurek, M.F.2    Tran, V.T.3    Chattha, G.4    Bird, E.D.5    Martin, J.B.6
  • 9
    • 0002089018 scopus 로고
    • Clinical genetics of familial Alzheimer disease
    • Terry RD, Katzman R, Bick KL (eds.), Raven Press: New York
    • Bird TD (1994) Clinical genetics of familial Alzheimer disease In. Alzheimer Disease, Terry RD, Katzman R, Bick KL (eds.), pp 65-74, Raven Press: New York,
    • (1994) Alzheimer Disease , pp. 65-74
    • Bird, T.D.1
  • 10
    • 0020077837 scopus 로고
    • Loss of neurons of origin of the adrenergic projection to cerebral cortex (nucleus locus ceruleus) in senile dementia
    • Bondareff W, Mountjoy CQ, Roth M (1982) Loss of neurons of origin of the adrenergic projection to cerebral cortex (nucleus locus ceruleus) in senile dementia. Neurology 32:164-168
    • (1982) Neurology , vol.32 , pp. 164-168
    • Bondareff, W.1    Mountjoy, C.Q.2    Roth, M.3
  • 11
    • 0001921207 scopus 로고
    • Neuropsychological features of memory disorders in Alzheimer disease
    • Terry RD, Katzman R, Bick KL (eds.), Raven Press: New York
    • Bondi MW, Salmon DP, Butters NM (1994) Neuropsychological features of memory disorders in Alzheimer disease. In: Alzheimer Disease, Terry RD, Katzman R, Bick KL (eds.), pp 41-63, Raven Press: New York.
    • (1994) Alzheimer Disease , pp. 41-63
    • Bondi, M.W.1    Salmon, D.P.2    Butters, N.M.3
  • 13
    • 0028813380 scopus 로고
    • Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function
    • Borchelt DR, Guarnieri M, Wong PC, Lee MK, Slunt HS, Xu Z, Sisodia SS, Price DL, Cleveland DW (1995) Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function J Biol Chem 270:3234-3238
    • (1995) J Biol Chem , vol.270 , pp. 3234-3238
    • Borchelt, D.R.1    Guarnieri, M.2    Wong, P.C.3    Lee, M.K.4    Slunt, H.S.5    Xu, Z.6    Sisodia, S.S.7    Price, D.L.8    Cleveland, D.W.9
  • 14
    • 0029975481 scopus 로고    scopus 로고
    • Age, neurofibrillary changes, Aβ-amyloid and the onset of Alzheimer's disease
    • Braak H, Braak E, Bohl J, Reintjes R (1996a) Age, neurofibrillary changes, Aβ-amyloid and the onset of Alzheimer's disease Neurosci Lett 210.87-90
    • (1996) Neurosci Lett , vol.210 , pp. 87-90
    • Braak, H.1    Braak, E.2    Bohl, J.3    Reintjes, R.4
  • 16
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H, Braak E (1991a) Neuropathological stageing of Alzheimer-related changes Acta Neuropathol 82:239-259
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 17
    • 0025968532 scopus 로고
    • Alzheimer's disease affects limbic nuclei of the thalamus
    • Braak H, Braak E (1991b) Alzheimer's disease affects limbic nuclei of the thalamus Acta Neuropathol 81:261-268
    • (1991) Acta Neuropathol , vol.81 , pp. 261-268
    • Braak, H.1    Braak, E.2
  • 18
    • 0001815909 scopus 로고
    • Pathology of Alzheimer's disease
    • Calne DB (ed.), W.B. Saunders: Philadelphia
    • Braak H, Braak E (1994) Pathology of Alzheimer's disease. In: Neurodegenerative Diseases, Calne DB (ed.), pp 585-613, W.B. Saunders: Philadelphia.
    • (1994) Neurodegenerative Diseases , pp. 585-613
    • Braak, H.1    Braak, E.2
  • 19
    • 0020507869 scopus 로고
    • Morphometric and biochemical studies of peripheral nerves in amyotrophic lateral sclerosis
    • Bradley WG, Good P, Rasool CG, Adelman LS (1983) Morphometric and biochemical studies of peripheral nerves in amyotrophic lateral sclerosis. Ann Neurol 14:267-277
    • (1983) Ann Neurol , vol.14 , pp. 267-277
    • Bradley, W.G.1    Good, P.2    Rasool, C.G.3    Adelman, L.S.4
  • 20
    • 0012081115 scopus 로고
    • Molecular pathology of Alzheimer amyloid and neurofibrillary tangles
    • Brion J-P (1990) Molecular pathology of Alzheimer amyloid and neurofibrillary tangles. Semin Neurosci 2:89-100
    • (1990) Semin Neurosci , vol.2 , pp. 89-100
    • Brion, J.-P.1
  • 22
    • 0029129227 scopus 로고
    • Spinal and bulbar muscular atrophy: A trinucleotide-repeat expansion neurodegenerative disease
    • Brooks BP, Fischbeck KH (1995) Spinal and bulbar muscular atrophy: a trinucleotide-repeat expansion neurodegenerative disease Trends Neurosci 18:459-461
    • (1995) Trends Neurosci , vol.18 , pp. 459-461
    • Brooks, B.P.1    Fischbeck, K.H.2
  • 23
    • 0029610443 scopus 로고
    • Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice
    • Brusa R, Zimmermann F, Koh D-S, Feldmeyer D, Gass P, Seeburg PH, Sprengel R (1995) Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice. Science 270:1677-1680
    • (1995) Science , vol.270 , pp. 1677-1680
    • Brusa, R.1    Zimmermann, F.2    Koh, D.-S.3    Feldmeyer, D.4    Gass, P.5    Seeburg, P.H.6    Sprengel, R.7
  • 27
    • 0024328536 scopus 로고
    • Altering the genome by homologous recombination
    • Capecchi MR (1989) Altering the genome by homologous recombination. Science 244:1288-1299
    • (1989) Science , vol.244 , pp. 1288-1299
    • Capecchi, M.R.1
  • 28
    • 0014336826 scopus 로고
    • Proximal axonal enlargement in motor neuron disease
    • Carpenter S (1968) Proximal axonal enlargement in motor neuron disease. Neurology 18:841-851
    • (1968) Neurology , vol.18 , pp. 841-851
    • Carpenter, S.1
  • 31
    • 0028178047 scopus 로고
    • Apolipoprotein E, ε4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: Analysis of the 19q13.2 chromosomal region
    • Chartier-Harlin M-C, Parfitt M, Legrain S, et al. (1994) Apolipoprotein E, ε4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region. Hum Mol Genet 3:569-574
    • (1994) Hum Mol Genet , vol.3 , pp. 569-574
    • Chartier-Harlin, M.-C.1    Parfitt, M.2    Legrain, S.3
  • 32
    • 0000581648 scopus 로고
    • Pathology-light microscopy of amyotrophic lateral sclerosis
    • Smith RA (ed.), Marcel Dekker: New York
    • Chou SM (1992) Pathology-light microscopy of amyotrophic lateral sclerosis In: Handbook of Amyotrophic Lateral Sclerosis, Smith RA (ed.), pp 133-181, Marcel Dekker: New York.
    • (1992) Handbook of Amyotrophic Lateral Sclerosis , pp. 133-181
    • Chou, S.M.1
  • 34
    • 0021139170 scopus 로고
    • Nucleus raphe dorsalis in dementia of the Alzheimer type: Neurofibrillary changes and neuronal packing density
    • Curcio CA, Kemper T (1984) Nucleus raphe dorsalis in dementia of the Alzheimer type: neurofibrillary changes and neuronal packing density. J Neuropathol Exp Neurol 43:359-368
    • (1984) J Neuropathol Exp Neurol , vol.43 , pp. 359-368
    • Curcio, C.A.1    Kemper, T.2
  • 36
    • 0027946294 scopus 로고
    • The development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis
    • Dal Canto MC, Gurney ME (1994a) The development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis. Am J Pathol 145.1-9
    • (1994) Am J Pathol , vol.145 , pp. 1-9
    • Dal Canto, M.C.1    Gurney, M.E.2
  • 37
    • 0027946294 scopus 로고
    • Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis
    • Dal Canto MC, Gurney ME (1994b) Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis. Am J Pathol 145:1271-1280
    • (1994) Am J Pathol , vol.145 , pp. 1271-1280
    • Dal Canto, M.C.1    Gurney, M.E.2
  • 38
    • 0028933344 scopus 로고
    • Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,ZN SOD, and in mice overexpressing wild type human SOD: A model of familial amyotrophic lateral sclerosis (FALS)
    • Dal Canto MC, Gurney ME (1995) Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,ZN SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS). Brain Res 676:25-40
    • (1995) Brain Res , vol.676 , pp. 25-40
    • Dal Canto, M.C.1    Gurney, M.E.2
  • 39
    • 0023106967 scopus 로고
    • A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease
    • Davies CA, Mann DMA, Sumpter PQ, Yates PO (1987) A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease. J Neurol Sci 78:151-164
    • (1987) J Neurol Sci , vol.78 , pp. 151-164
    • Davies, C.A.1    Mann, D.M.A.2    Sumpter, P.Q.3    Yates, P.O.4
  • 40
    • 0019256571 scopus 로고
    • Reduced somato-statin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementia
    • Davies P, Katzman R, Terry RD (1980) Reduced somato-statin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementia. Nature 288:279-280
    • (1980) Nature , vol.288 , pp. 279-280
    • Davies, P.1    Katzman, R.2    Terry, R.D.3
  • 41
    • 0027511389 scopus 로고
    • The role of cortical connectvity in Alzheimer's disease pathogenesis: A review and model system
    • De LaCoste M-C, White CL, III (1993) The role of cortical connectvity in Alzheimer's disease pathogenesis: a review and model system. Neurobiol Aging 14:1-16
    • (1993) Neurobiol Aging , vol.14 , pp. 1-16
    • De LaCoste, M.-C.1    White III, C.L.2
  • 42
    • 0022573696 scopus 로고
    • Reciprocal changes in corticotrophin-releasing factor (CRF)-like immunoractivity and CRF receptors in cerebral cortex of Alzheimer's disease
    • De Souza EB, Whitehouse PJ, Kuhar MJ, Price DL, Vale WW (1986) Reciprocal changes in corticotrophin-releasing factor (CRF)-like immunoractivity and CRF receptors in cerebral cortex of Alzheimer's disease. Nature 319:593-595
    • (1986) Nature , vol.319 , pp. 593-595
    • De Souza, E.B.1    Whitehouse, P.J.2    Kuhar, M.J.3    Price, D.L.4    Vale, W.W.5
  • 44
    • 0025269152 scopus 로고
    • Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive seventy
    • DeKosky ST, Scheff SW (1990) Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive seventy. Ann Neurol 27.457-463
    • (1990) Ann Neurol , vol.27 , pp. 457-463
    • DeKosky, S.T.1    Scheff, S.W.2
  • 46
    • 0028109336 scopus 로고
    • The US economic and social costs of Alzheimer's disease revisited
    • Ernst RL, Hay JW (1994) The US economic and social costs of Alzheimer's disease revisited. Am J Public Health 84:1261-1264
    • (1994) Am J Public Health , vol.84 , pp. 1261-1264
    • Ernst, R.L.1    Hay, J.W.2
  • 53
    • 0028113971 scopus 로고
    • The apolipoprotein E allele ε4 is over-represented in patients with the Lewy body variant of Alzheimer's disease
    • Galasko D, Saitoh T, Xia Y, Thai LJ, Katzman R, Hill LR, Hansen L (1994) The apolipoprotein E allele ε4 is over-represented in patients with the Lewy body variant of Alzheimer's disease. Neurology 44:1950-1951
    • (1994) Neurology , vol.44 , pp. 1950-1951
    • Galasko, D.1    Saitoh, T.2    Xia, Y.3    Thai, L.J.4    Katzman, R.5    Hill, L.R.6    Hansen, L.7
  • 55
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA framentation
    • Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA framentation. J Cell Biol 119:493-501
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 56
    • 0021256895 scopus 로고
    • Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
    • Glenner GG, Wong CW (1984a) Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 120.885-890
    • (1984) Biochem Biophys Res Commun , vol.120 , pp. 885-890
    • Glenner, G.G.1    Wong, C.W.2
  • 57
    • 0021207461 scopus 로고
    • Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein
    • Glenner GG, Wong CW (1984b) Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein. Biochem Biophys Res Commun 122:1131-1135
    • (1984) Biochem Biophys Res Commun , vol.122 , pp. 1131-1135
    • Glenner, G.G.1    Wong, C.W.2
  • 59
    • 0026231697 scopus 로고
    • Neurofibrillary tangles and β-amyloid deposits in Alzheimer's disease
    • Goedert M, Sisodia SS, Price DL (1991) Neurofibrillary tangles and β-amyloid deposits in Alzheimer's disease. Curr Opin Neurobiol 1:441-447
    • (1991) Curr Opin Neurobiol , vol.1 , pp. 441-447
    • Goedert, M.1    Sisodia, S.S.2    Price, D.L.3
  • 61
    • 0023132387 scopus 로고
    • Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease
    • Goldgaber D, Lerman MI, McBride OW, Saffiotti U, Gajdusek DC (1987) Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease. Science 235:877-880
    • (1987) Science , vol.235 , pp. 877-880
    • Goldgaber, D.1    Lerman, M.I.2    McBride, O.W.3    Saffiotti, U.4    Gajdusek, D.C.5
  • 64
    • 0020334692 scopus 로고
    • Dentatorubro-pallidoluysian degeneration: Clinical, neuro-ophthalmologic, biochemical, and pathologic studies on autosomal dominant form
    • Goto I, Tobimatsu S, Ohta M, Hosokawa S, Shibasaki H, Kuroiwa Y (1982) Dentatorubro-pallidoluysian degeneration: clinical, neuro-ophthalmologic, biochemical, and pathologic studies on autosomal dominant form. Neurology (NY) 32:1395-1399
    • (1982) Neurology (NY) , vol.32 , pp. 1395-1399
    • Goto, I.1    Tobimatsu, S.2    Ohta, M.3    Hosokawa, S.4    Shibasaki, H.5    Kuroiwa, Y.6
  • 65
    • 0025292866 scopus 로고
    • A preparation of Alzheimer paired helical filaments that displays distinct τ proteins by polyacrylamide gel electrophoresis
    • Greenberg SG, Davies P (1990) A preparation of Alzheimer paired helical filaments that displays distinct τ proteins by polyacrylamide gel electrophoresis. Proc Natl Acad Sci USA 87:5827-5831
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5827-5831
    • Greenberg, S.G.1    Davies, P.2
  • 67
    • 0027280936 scopus 로고
    • Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting
    • Gu H, Zou Y-R, Rajewsky K (1993) Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Cell 73:1155-1164
    • (1993) Cell , vol.73 , pp. 1155-1164
    • Gu, H.1    Zou, Y.-R.2    Rajewsky, K.3
  • 68
    • 0028059099 scopus 로고
    • Deletion of a DNA polymerase β gene segment in T cells using cell type-specific gene targeting
    • Gu H, Marth JD, Orban PC, Mossman H, Rajewsky K (1994) Deletion of a DNA polymerase β gene segment in T cells using cell type-specific gene targeting. Science 265:103-106
    • (1994) Science , vol.265 , pp. 103-106
    • Gu, H.1    Marth, J.D.2    Orban, P.C.3    Mossman, H.4    Rajewsky, K.5
  • 70
    • 0030050727 scopus 로고    scopus 로고
    • Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
    • Gurney ME, Cuttings FB, Zhai P, Doble A, Taylor CP, Andrus PK, Hall ED (1996) Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann Neurol 39.147-157
    • (1996) Ann Neurol , vol.39 , pp. 147-157
    • Gurney, M.E.1    Cuttings, F.B.2    Zhai, P.3    Doble, A.4    Taylor, C.P.5    Andrus, P.K.6    Hall, E.D.7
  • 71
    • 0024595972 scopus 로고
    • Synaptic loss in Alzheimer's disease and other dementias
    • Hamos JE, DeGennaro LJ, Drachmen DA (1989) Synaptic loss in Alzheimer's disease and other dementias. Neurology 39:355-361
    • (1989) Neurology , vol.39 , pp. 355-361
    • Hamos, J.E.1    DeGennaro, L.J.2    Drachmen, D.A.3
  • 72
    • 0029113929 scopus 로고
    • Inherited ataxias
    • Harding AE (1995) Inherited ataxias. Curr Opin Neurol 8:306-309
    • (1995) Curr Opin Neurol , vol.8 , pp. 306-309
    • Harding, A.E.1
  • 74
    • 0000533076 scopus 로고
    • Myotonic dystrophy
    • Engel AG, Franzini-Armstrong C (eds.), McGraw-Hill, Inc.: New York
    • Harper PS, Rüdel R (1994) Myotonic dystrophy. In: Myology. Basic and Clinical, Engel AG, Franzini-Armstrong C (eds.), pp 1192-1219, McGraw-Hill, Inc.: New York.
    • (1994) Myology. Basic and Clinical , pp. 1192-1219
    • Harper, P.S.1    Rüdel, R.2
  • 75
    • 0025885733 scopus 로고
    • Neuronal loss in layers V and VI of cerebral cortex in Huntington's disease
    • Hedreen JC, Peyser CE, Folstein SE, Ross CA (1991) Neuronal loss in layers V and VI of cerebral cortex in Huntington's disease. Neurosci Lett 133:257-261
    • (1991) Neurosci Lett , vol.133 , pp. 257-261
    • Hedreen, J.C.1    Peyser, C.E.2    Folstein, S.E.3    Ross, C.A.4
  • 78
    • 0018928275 scopus 로고
    • Amygdaloid changes in aging and dementia
    • Herzog AG, Kemper TL (1980) Amygdaloid changes in aging and dementia Arch Neurol 37.625-629
    • (1980) Arch Neurol , vol.37 , pp. 625-629
    • Herzog, A.G.1    Kemper, T.L.2
  • 79
    • 0028232799 scopus 로고
    • Transgenic mouse brain histopathology resembles early Alzheimer's disease
    • Higgins LS, Holtzman DM, Rabin J, Mobley WC, Cordell B (1994) Transgenic mouse brain histopathology resembles early Alzheimer's disease. Ann Neurol 35:598-607
    • (1994) Ann Neurol , vol.35 , pp. 598-607
    • Higgins, L.S.1    Holtzman, D.M.2    Rabin, J.3    Mobley, W.C.4    Cordell, B.5
  • 81
    • 0000435636 scopus 로고
    • Fine structural study of sporadic and familial amyotrophic lateral sclerosis
    • Smith RA (ed.), Marcel Dekker: New York
    • Hirano A, Kato S (1992) Fine structural study of sporadic and familial amyotrophic lateral sclerosis. In: Handbook of Amyotrophic Lateral Sclerosis, Smith RA (ed.), pp 183-192, Marcel Dekker: New York.
    • (1992) Handbook of Amyotrophic Lateral Sclerosis , pp. 183-192
    • Hirano, A.1    Kato, S.2
  • 84
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • Huntington's Disease Collaborative Research Group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72:971-983
    • (1993) Cell , vol.72 , pp. 971-983
  • 85
    • 0021145680 scopus 로고
    • Alzheimer's disease: Cell-specific pathology isolates the hippocampal formation
    • Hyman BT, Van Hoesen GW, Damasio AR, Barnes CL (1984) Alzheimer's disease: cell-specific pathology isolates the hippocampal formation. Science 225:1168-1170
    • (1984) Science , vol.225 , pp. 1168-1170
    • Hyman, B.T.1    Van Hoesen, G.W.2    Damasio, A.R.3    Barnes, C.L.4
  • 86
    • 0022535539 scopus 로고
    • Perforant pathway changes and the memory impairment of Alzheimer's disease
    • Hyman BT, Van Hoesen GW, Kromer LJ, Damasio AR (1986) Perforant pathway changes and the memory impairment of Alzheimer's disease Ann Neurol 20:472-481
    • (1986) Ann Neurol , vol.20 , pp. 472-481
    • Hyman, B.T.1    Van Hoesen, G.W.2    Kromer, L.J.3    Damasio, A.R.4
  • 87
    • 0025107676 scopus 로고
    • Memory-related neural systems in Alzheimer's disease: An anatomic study
    • Hyman BT, Van Hoesen GW, Damasio AR (1990) Memory-related neural systems in Alzheimer's disease: an anatomic study. Neurology 40:1721-1730
    • (1990) Neurology , vol.40 , pp. 1721-1730
    • Hyman, B.T.1    Van Hoesen, G.W.2    Damasio, A.R.3
  • 88
    • 85047678013 scopus 로고
    • Dentato-rubropallido-luysian atrophy: A clinico-pathological study
    • lizuka R, Hirayama K, Maehara K (1984) Dentato-rubropallido-luysian atrophy: a clinico-pathological study. J Neurol Neurosurg Psychiatry 47.1288-1298
    • (1984) J Neurol Neurosurg Psychiatry , vol.47 , pp. 1288-1298
    • Lizuka, R.1    Hirayama, K.2    Maehara, K.3
  • 89
    • 0028169925 scopus 로고
    • Visualization of Aβ42(43)-positive and Aβ40-positive senile plaques with end-specific Aβ-monoclonal antibodies. evidence that an initially deposited Aβ species is Aβ1-42(43)
    • Iwatsubo T, Odaka A, Suzuki N, Mizusawa H, Nukina N, Ihara Y (1994) Visualization of Aβ42(43)-positive and Aβ40-positive senile plaques with end-specific Aβ-monoclonal antibodies. evidence that an initially deposited Aβ species is Aβ1-42(43). Neuron 13:45-53
    • (1994) Neuron , vol.13 , pp. 45-53
    • Iwatsubo, T.1    Odaka, A.2    Suzuki, N.3    Mizusawa, H.4    Nukina, N.5    Ihara, Y.6
  • 91
    • 84988043549 scopus 로고
    • How trinucleotide repeats may function
    • Jennings C (1995) How trinucleotide repeats may function. Nature 378:127
    • (1995) Nature , vol.378 , pp. 127
    • Jennings, C.1
  • 92
    • 0029690663 scopus 로고    scopus 로고
    • Machado-Joseph disease and SCA3: The genotype meets the phenotypes
    • Junck L, Fink JK (1996) Machado-Joseph disease and SCA3: the genotype meets the phenotypes. Neurology 46:4-8
    • (1996) Neurology , vol.46 , pp. 4-8
    • Junck, L.1    Fink, J.K.2
  • 94
    • 85015880852 scopus 로고
    • Neuropathology in amyotrophic lateral sclerosis patients on respirators, uniformity and diversity in 13 cases
    • Kato S, Oda M, Hayashi H (1993) Neuropathology in amyotrophic lateral sclerosis patients on respirators, uniformity and diversity in 13 cases. Neuropathology 13:229-236
    • (1993) Neuropathology , vol.13 , pp. 229-236
    • Kato, S.1    Oda, M.2    Hayashi, H.3
  • 95
    • 0028171886 scopus 로고
    • Apolipoprotein E and Alzheimer's disease
    • Katzman R (1994) Apolipoprotein E and Alzheimer's disease. Curr Opin Neurobiol 4:703-707
    • (1994) Curr Opin Neurobiol , vol.4 , pp. 703-707
    • Katzman, R.1
  • 97
    • 0001804233 scopus 로고
    • Neuroanatomical and neuropathological changes in normal aging and in dementia
    • Albert ML (ed.), Oxford University Press: New York
    • Kemper T (1984) Neuroanatomical and neuropathological changes in normal aging and in dementia. In: Clinical Neurology of Aging, Albert ML (ed.), pp 9-52, Oxford University Press: New York.
    • (1984) Clinical Neurology of Aging , pp. 9-52
    • Kemper, T.1
  • 98
    • 0023872043 scopus 로고
    • Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity
    • Kitaguchi N, Takahashi Y, Tokushima Y, Shiojiri S, Ito H (1988) Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity. Nature 331:530-532
    • (1988) Nature , vol.331 , pp. 530-532
    • Kitaguchi, N.1    Takahashi, Y.2    Tokushima, Y.3    Shiojiri, S.4    Ito, H.5
  • 103
    • 0025879957 scopus 로고
    • An in vivo model for the neurodegenerative effects of β amyloid and protection by substance P
    • Kowall NW, Beal MF, Busciglio J, Duffy LK, Yankner BA (1991) An in vivo model for the neurodegenerative effects of β amyloid and protection by substance P. Proc Natl Acad Sci USA 88:7247-7251
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7247-7251
    • Kowall, N.W.1    Beal, M.F.2    Busciglio, J.3    Duffy, L.K.4    Yankner, B.A.5
  • 104
    • 0026078330 scopus 로고
    • Glutamate-, glutaminase-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease
    • Kowall NW, Beal MF (1991) Glutamate-, glutaminase-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease. Ann Neurol 29:162-167
    • (1991) Ann Neurol , vol.29 , pp. 162-167
    • Kowall, N.W.1    Beal, M.F.2
  • 105
  • 106
    • 0028981717 scopus 로고
    • The Alzheimer's Aβ peptide induces neurodegeneration and apoptotic cell death in transgenic mice
    • LaFerla FM, Tinkle BT, Biebench CJ, Haudenschild CC, Jay G (1995) The Alzheimer's Aβ peptide induces neurodegeneration and apoptotic cell death in transgenic mice. Nature Genetics 9.21-30
    • (1995) Nature Genetics , vol.9 , pp. 21-30
    • LaFerla, F.M.1    Tinkle, B.T.2    Biebench, C.J.3    Haudenschild, C.C.4    Jay, G.5
  • 109
    • 0025904444 scopus 로고
    • A68: A major subunit of paired helical filaments and derivatized forms of normal tau
    • Lee VM-Y, Balin BJ, Otvos L, Jr, Trojanowski JQ (1991) A68: a major subunit of paired helical filaments and derivatized forms of normal tau. Science 251:675-678
    • (1991) Science , vol.251 , pp. 675-678
    • Lee, V.M.-Y.1    Balin, B.J.2    Otvos Jr., L.3    Trojanowski, J.Q.4
  • 110
    • 0028894984 scopus 로고
    • Disruption of the cytoskeleton in Alzheimer's disease
    • Lee VM-Y (1995) Disruption of the cytoskeleton in Alzheimer's disease. Curr Opin Neurobiol 5:663-668
    • (1995) Curr Opin Neurobiol , vol.5 , pp. 663-668
    • Lee, V.M.-Y.1
  • 111
    • 0026941497 scopus 로고
    • The disordered neuronal cytoskeleton in Alzheimer's disease
    • Lee VM-Y, Trojanowski JQ (1992) The disordered neuronal cytoskeleton in Alzheimer's disease. Curr Opin Neurobiol 2:653-656
    • (1992) Curr Opin Neurobiol , vol.2 , pp. 653-656
    • Lee, V.M.-Y.1    Trojanowski, J.Q.2
  • 113
    • 0029116848 scopus 로고
    • Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene
    • Levitan D, Greenwald I (1995) Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene. Nature 377-351-354
    • (1995) Nature , vol.377 , pp. 351-354
    • Levitan, D.1    Greenwald, I.2
  • 117
    • 0029618686 scopus 로고
    • Identification and expression analysis of a potential familial Alzheimer disease gene on chromosome 1 related to AD3
    • Li J, Ma J, Potter H (1995) Identification and expression analysis of a potential familial Alzheimer disease gene on chromosome 1 related to AD3. Proc Natl Acad Sci USA 92:12180-12184
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 12180-12184
    • Li, J.1    Ma, J.2    Potter, H.3
  • 118
    • 0027297703 scopus 로고
    • Novel triplet repeat containing genes in human brain: Cloning, expression, and length polymorphisms
    • Li S-H, Mclnnis MG, Margolis RL, Antonarakis SE, Ross CA (1993) Novel triplet repeat containing genes in human brain: cloning, expression, and length polymorphisms. Genomics 16:572-579
    • (1993) Genomics , vol.16 , pp. 572-579
    • Li, S.-H.1    Mclnnis, M.G.2    Margolis, R.L.3    Antonarakis, S.E.4    Ross, C.A.5
  • 120
    • 0028134969 scopus 로고
    • The requirement for yeast superoxide dismutase is bypassed through mutations in BSD2, a novel metal homeostasis gene
    • Liu XF, Cizewski Culotta V (1994) The requirement for yeast superoxide dismutase is bypassed through mutations in BSD2, a novel metal homeostasis gene. Mol Cell Biol 14.7037-7045
    • (1994) Mol Cell Biol , vol.14 , pp. 7037-7045
    • Liu, X.F.1    Cizewski Culotta, V.2
  • 122
    • 0024299370 scopus 로고
    • Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
    • Mahley RW (1988) Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 240:622-630
    • (1988) Science , vol.240 , pp. 622-630
    • Mahley, R.W.1
  • 123
    • 0023891743 scopus 로고
    • The progression of the pathological changes of Alzheimer's disease in frontal and temporal neocortex examined both at biopsy and at autopsy
    • Mann DMA, Marcyniuk B, Yates PO, Neary D, Snowden JS (1988) The progression of the pathological changes of Alzheimer's disease in frontal and temporal neocortex examined both at biopsy and at autopsy. Neuropathol Appl Neurobiol 14:177-195
    • (1988) Neuropathol Appl Neurobiol , vol.14 , pp. 177-195
    • Mann, D.M.A.1    Marcyniuk, B.2    Yates, P.O.3    Neary, D.4    Snowden, J.S.5
  • 124
    • 0024364877 scopus 로고
    • Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease
    • Masliah E, Terry RD, DeTeresa RM, Hansen LA (1989) Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease. Neurosci Lett 103:234-239
    • (1989) Neurosci Lett , vol.103 , pp. 234-239
    • Masliah, E.1    Terry, R.D.2    Deteresa, R.M.3    Hansen, L.A.4
  • 125
    • 0025330775 scopus 로고
    • Quantitative immunohistochemistry of synaptophysin in human neocortex: An alternative method to estimate density of presynaptic terminals in paraffin sections
    • Masliah E, Terry RD, Alford M, DeTeresa R (1990) Quantitative immunohistochemistry of synaptophysin in human neocortex: an alternative method to estimate density of presynaptic terminals in paraffin sections. J Histochem Cytochem 38 837-844
    • (1990) J Histochem Cytochem , vol.38 , pp. 837-844
    • Masliah, E.1    Terry, R.D.2    Alford, M.3    DeTeresa, R.4
  • 126
    • 0025970091 scopus 로고
    • Immunoelectron microscopic study of synaptic pathology in Alzheimer's disease
    • Masliah E, Hansen L, Albnght T, Mallory M, Terry RD (1991) Immunoelectron microscopic study of synaptic pathology in Alzheimer's disease. Acta Neuropathol 81.428-433
    • (1991) Acta Neuropathol , vol.81 , pp. 428-433
    • Masliah, E.1    Hansen, L.2    Albnght, T.3    Mallory, M.4    Terry, R.D.5
  • 128
    • 0022156464 scopus 로고
    • Neuronal origin of a cerebral amyloid: Neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels
    • Masters CL, Multhaup G, Simms G, Pottgiesser J, Martins RN, Beyreuther K (1985a) Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels EMBO J 4:2757-2763
    • (1985) EMBO J , vol.4 , pp. 2757-2763
    • Masters, C.L.1    Multhaup, G.2    Simms, G.3    Pottgiesser, J.4    Martins, R.N.5    Beyreuther, K.6
  • 130
    • 0026692757 scopus 로고
    • Basophilic inclusions in sporadic juvenile amyotrophic lateral sclerosis: An immunocytochemical and ultrastructural study
    • Matsumoto S, Kusaka H, Murakami N, Hashizume Y, Okazaki H, Hirano A (1992) Basophilic inclusions in sporadic juvenile amyotrophic lateral sclerosis: an immunocytochemical and ultrastructural study. Acta Neuropathol 83:579-583
    • (1992) Acta Neuropathol , vol.83 , pp. 579-583
    • Matsumoto, S.1    Kusaka, H.2    Murakami, N.3    Hashizume, Y.4    Okazaki, H.5    Hirano, A.6
  • 132
    • 0029055738 scopus 로고
    • Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human β-amyloid precursor protein
    • Moran PM, Higgins LS, Cordell B, Moser PC (1995) Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human β-amyloid precursor protein. Proc Natl Acad Sci USA 92:5341-5345
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5341-5345
    • Moran, P.M.1    Higgins, L.S.2    Cordell, B.3    Moser, P.C.4
  • 133
    • 0029890685 scopus 로고    scopus 로고
    • The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease
    • Mourelatos Z, Gonatas NK, Stieber A, Gurney ME, Dal Canto MC (1996) The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease. Proc Natl Acad Sci USA 93:5472-5477
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5472-5477
    • Mourelatos, Z.1    Gonatas, N.K.2    Stieber, A.3    Gurney, M.E.4    Dal Canto, M.C.5
  • 136
    • 0020064620 scopus 로고
    • Familial myoclonus epilepsy and choreoathetosis: Hereditary dentatorubral-pallidoluysian atrophy
    • Naito H, Oyanagi S (1982) Familial myoclonus epilepsy and choreoathetosis: hereditary dentatorubral-pallidoluysian atrophy Neurology (NY) 32:798-807
    • (1982) Neurology (NY) , vol.32 , pp. 798-807
    • Naito, H.1    Oyanagi, S.2
  • 137
    • 0027946816 scopus 로고
    • Predictive value of apolipoprotein E genotyping in Alzheimer's disease. results of an autopsy series and an analysis of several combined studies
    • Nalbantoglu J, Gilfix BM, Bertrand P, Robitaille Y, Gauthier S, Rosenblatt DS, Poirier J (1994) Predictive value of apolipoprotein E genotyping in Alzheimer's disease. results of an autopsy series and an analysis of several combined studies. Ann Neurol 36:889-895
    • (1994) Ann Neurol , vol.36 , pp. 889-895
    • Nalbantoglu, J.1    Gilfix, B.M.2    Bertrand, P.3    Robitaille, Y.4    Gauthier, S.5    Rosenblatt, D.S.6    Poirier, J.7
  • 139
    • 0002841337 scopus 로고
    • Diseases of the basal ganglia, cerebellum and motor neurons
    • Adams JH, Duchen LW (eds.), Oxford University Press: New York
    • Oppenheimer DR, Esin MM (1992) Diseases of the basal ganglia, cerebellum and motor neurons. In: Greenfield's Neuropathology, Adams JH, Duchen LW (eds.), pp 988-1045. Oxford University Press: New York
    • (1992) Greenfield's Neuropathology , pp. 988-1045
    • Oppenheimer, D.R.1    Esin, M.M.2
  • 140
    • 0023133252 scopus 로고
    • Apolipoprotein E isoform phenotyping methodology and population frequency with identification of apoE1 and apoE5 isoforms
    • Ordovas JM, Litwack-Klein L, Wilson PWF, Schaefer MM, Schaefer EJ (1987) Apolipoprotein E isoform phenotyping methodology and population frequency with identification of apoE1 and apoE5 isoforms. J Lipid Res 28:371-380
    • (1987) J Lipid Res , vol.28 , pp. 371-380
    • Ordovas, J.M.1    Litwack-Klein, L.2    Wilson, P.W.F.3    Schaefer, M.M.4    Schaefer, E.J.5
  • 143
    • 0028815433 scopus 로고
    • Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons
    • Pardo CA, Xu Z, Borchelt DR, Price DL, Sisodia SS, Cleveland DW (1995) Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons. Proc Natl Acad Sci USA 92:954-958
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 954-958
    • Pardo, C.A.1    Xu, Z.2    Borchelt, D.R.3    Price, D.L.4    Sisodia, S.S.5    Cleveland, D.W.6
  • 146
    • 0022645755 scopus 로고
    • The cholinergic hypothesis - Ten years on
    • Perry EK (1986) The cholinergic hypothesis - ten years on. Br Med Bull 42:63-69
    • (1986) Br Med Bull , vol.42 , pp. 63-69
    • Perry, E.K.1
  • 147
    • 0020284775 scopus 로고
    • Extensive loss of choline acetyltransferase activity is not reflected by neuronal loss in the nucleus of Meynert in Alzheimer's disease
    • Perry RH, Candy JM, Perry EK, Irving D, Blessed G, Fairbairn AF, Tomlinson BE (1982) Extensive loss of choline acetyltransferase activity is not reflected by neuronal loss in the nucleus of Meynert in Alzheimer's disease. Neurosci Lett 33:311-315
    • (1982) Neurosci Lett , vol.33 , pp. 311-315
    • Perry, R.H.1    Candy, J.M.2    Perry, E.K.3    Irving, D.4    Blessed, G.5    Fairbairn, A.F.6    Tomlinson, B.E.7
  • 148
    • 0025283203 scopus 로고
    • Dentatorubro-pallidoluysian atrophy of the myoclonus epilepsy type with posterior column degeneration
    • Pfeiffer RF, McComb RD (1990) Dentatorubro-pallidoluysian atrophy of the myoclonus epilepsy type with posterior column degeneration. Mov Disord 5:134-138
    • (1990) Mov Disord , vol.5 , pp. 134-138
    • Pfeiffer, R.F.1    McComb, R.D.2
  • 149
    • 0025733411 scopus 로고
    • Aggregation- related toxicity of synthetic β-amyloid protein in hippocampal cultures
    • Pike CJ, Walencewicz AJ, Glabe CG, Cotman CW (1991) Aggregation- related toxicity of synthetic β-amyloid protein in hippocampal cultures, Eur J Pharmacol 207.367-368
    • (1991) Eur J Pharmacol , vol.207 , pp. 367-368
    • Pike, C.J.1    Walencewicz, A.J.2    Glabe, C.G.3    Cotman, C.W.4
  • 150
    • 0027282035 scopus 로고
    • Apolipoprotein E polymorphism and Alzheimer's disease
    • Poirier J, Davignon J, Bouthillier D, et al. (1993) Apolipoprotein E polymorphism and Alzheimer's disease. Lancet 342:697-699
    • (1993) Lancet , vol.342 , pp. 697-699
    • Poirier, J.1    Davignon, J.2    Bouthillier, D.3
  • 153
    • 0029072690 scopus 로고
    • Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models
    • Portera-Cailliau C, Hedreen JC, Price DL, Koliatsos VE (1995) Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models J Neurosci 15:3775-3787
    • (1995) J Neurosci , vol.15 , pp. 3775-3787
    • Portera-Cailliau, C.1    Hedreen, J.C.2    Price, D.L.3    Koliatsos, V.E.4
  • 154
    • 0026739087 scopus 로고
    • Toxicity of synthetic Aβ peptides and modeling of Alzheimer's disease
    • Price DL, Borchelt DR, Walker LC, Sisodia SS (1992) Toxicity of synthetic Aβ peptides and modeling of Alzheimer's disease. Neurobiol Aging 13:623-625
    • (1992) Neurobiol Aging , vol.13 , pp. 623-625
    • Price, D.L.1    Borchelt, D.R.2    Walker, L.C.3    Sisodia, S.S.4
  • 155
    • 0028243033 scopus 로고
    • Cellular and molecular biology of Alzheimer's disease and animal models
    • Price DL, Sisodia SS (1994) Cellular and molecular biology of Alzheimer's disease and animal models Annu Rev Med 45:435-446
    • (1994) Annu Rev Med , vol.45 , pp. 435-446
    • Price, D.L.1    Sisodia, S.S.2
  • 156
    • 0026042933 scopus 로고
    • Deposition of β/A4 protein along neuronal plasma membranes in diffuse senile plaques
    • Probst A, Langui D, Ipsen S, Robakis N, Ulrich J (1991) Deposition of β/A4 protein along neuronal plasma membranes in diffuse senile plaques Acta Neuropathol 83:21-29
    • (1991) Acta Neuropathol , vol.83 , pp. 21-29
    • Probst, A.1    Langui, D.2    Ipsen, S.3    Robakis, N.4    Ulrich, J.5
  • 159
    • 0027374047 scopus 로고
    • Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions
    • Rebeck GW, Reiter JS, Strickland DK, Hyman BT (1993) Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions Neuron 11:575-580
    • (1993) Neuron , vol.11 , pp. 575-580
    • Rebeck, G.W.1    Reiter, J.S.2    Strickland, D.K.3    Hyman, B.T.4
  • 160
    • 0028888945 scopus 로고
    • Transgenic mice expressing an altered murine superoxide dismutase gene
    • Ripps ME, Huntley GW, Hof PR, Morrison JH, Gordon JW (1995) Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. Proc Natl Acad Sci USA 92:689-693
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 689-693
    • Ripps, M.E.1    Huntley, G.W.2    Hof, P.R.3    Morrison, J.H.4    Gordon, J.W.5
  • 161
    • 2142777413 scopus 로고
    • Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides
    • Robakis NK, Ramakrishna N, Wolfe G, Wisniewski HM (1987a) Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides. Proc Natl Acad Sci USA 84:4190-4194
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 4190-4194
    • Robakis, N.K.1    Ramakrishna, N.2    Wolfe, G.3    Wisniewski, H.M.4
  • 164
    • 0022550027 scopus 로고
    • Purification, ultrastructure, and chemical analysis of Alzheimer disease amyloid plaque core protein
    • Roher A, Wolfe D, Palutke M, KuKurga D (1986) Purification, ultrastructure, and chemical analysis of Alzheimer disease amyloid plaque core protein. Proc Natl Acad Sci USA 83:2662-2666
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 2662-2666
    • Roher, A.1    Wolfe, D.2    Palutke, M.3    Kukurga, D.4
  • 166
    • 0027936838 scopus 로고
    • Apolipoprotein E affects the rate of Alzheimer disease expression: β-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease
    • Roses AD (1994) Apolipoprotein E affects the rate of Alzheimer disease expression: β-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease. J Neuropathol Exp Neurol 53:429-437
    • (1994) J Neuropathol Exp Neurol , vol.53 , pp. 429-437
    • Roses, A.D.1
  • 168
    • 0028997817 scopus 로고
    • Apolipoprotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease
    • Roses AD (1995) Apolipoprotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease. Ann Neurol 38 6-14
    • (1995) Ann Neurol , vol.38 , pp. 6-14
    • Roses, A.D.1
  • 169
    • 0027300219 scopus 로고
    • Genes with triplet repeats: Candidate mediators of neuropsychiatric disorders
    • Ross CA, Mclnnis MG, Margolis RL, Li S-H (1993) Genes with triplet repeats: candidate mediators of neuropsychiatric disorders. Trends Neurosci 16:254-260
    • (1993) Trends Neurosci , vol.16 , pp. 254-260
    • Ross, C.A.1    Mclnnis, M.G.2    Margolis, R.L.3    Li, S.-H.4
  • 170
    • 0019254568 scopus 로고
    • Reduced amounts of immunoreactive somatostatin in the temporal cortex in senile dementia of Alzheimer type
    • Rossor MN, Emson PC, Mountjoy CQ, Roth M, Iversen LL (1980) Reduced amounts of immunoreactive somatostatin in the temporal cortex in senile dementia of Alzheimer type. Neurosci Lett 20:373-377
    • (1980) Neurosci Lett , vol.20 , pp. 373-377
    • Rossor, M.N.1    Emson, P.C.2    Mountjoy, C.Q.3    Roth, M.4    Iversen, L.L.5
  • 173
    • 0027464687 scopus 로고
    • A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice
    • Schedl A, Montoliu L, Kelsey G, Schütz G (1993) A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice. Nature 362:258-261
    • (1993) Nature , vol.362 , pp. 258-261
    • Schedl, A.1    Montoliu, L.2    Kelsey, G.3    Schütz, G.4
  • 174
    • 0027400026 scopus 로고
    • Synapse loss in the temporal lobe in Alzheimer's disease
    • Scheff SW, Price DA (1993) Synapse loss in the temporal lobe in Alzheimer's disease. Ann Neurol 33:190-199
    • (1993) Ann Neurol , vol.33 , pp. 190-199
    • Scheff, S.W.1    Price, D.A.2
  • 175
    • 0029115570 scopus 로고
    • Progress in Alzheimer's disease genetics
    • Schellenberg GD (1995) Progress in Alzheimer's disease genetics. Curr Opin Neurol 8:262-267
    • (1995) Curr Opin Neurol , vol.8 , pp. 262-267
    • Schellenberg, G.D.1
  • 176
    • 0027086835 scopus 로고
    • Chimeric prion protein expression in cultured cells and transgenic mice
    • Scott MR, Köhler R, Foster D, Prusiner SB (1992) Chimeric prion protein expression in cultured cells and transgenic mice. Protein Sci 1:986-997
    • (1992) Protein Sci , vol.1 , pp. 986-997
    • Scott, M.R.1    Köhler, R.2    Foster, D.3    Prusiner, S.B.4
  • 178
    • 0023118252 scopus 로고
    • Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease
    • Selkoe DJ, Bell DS, Podlisny MB, Price DL, Cork LC (1987) Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease. Science 235:873-877
    • (1987) Science , vol.235 , pp. 873-877
    • Selkoe, D.J.1    Bell, D.S.2    Podlisny, M.B.3    Price, D.L.4    Cork, L.C.5
  • 179
    • 0029027649 scopus 로고
    • Missense on the membrane
    • Selkoe DJ (1995) Missense on the membrane. Nature 375:734-735
    • (1995) Nature , vol.375 , pp. 734-735
    • Selkoe, D.J.1
  • 180
    • 0029991245 scopus 로고    scopus 로고
    • Neurobiology of Huntington's disease
    • Sharp AH, Ross CA (1996) Neurobiology of Huntington's disease. Neurobiol Dis 3:3-15
    • (1996) Neurobiol Dis , vol.3 , pp. 3-15
    • Sharp, A.H.1    Ross, C.A.2
  • 182
    • 85015902212 scopus 로고
    • Immunohistochemical demonstration of Cu/Zn superoxide dismutase in the spinal cord of patients with familial amyotrophic lateral sclerosis
    • Shibata N, Hirano M, Kobayashi K (1993) Immunohistochemical demonstration of Cu/Zn superoxide dismutase in the spinal cord of patients with familial amyotrophic lateral sclerosis. Acta Histochem Cytochem 26:619-622
    • (1993) Acta Histochem Cytochem , vol.26 , pp. 619-622
    • Shibata, N.1    Hirano, M.2    Kobayashi, K.3
  • 183
    • 0029927679 scopus 로고    scopus 로고
    • Intense superoxide dismutase-1 immunoreactivity in intracytoplasmic hyaline inclusions of familial amyotrophic lateral sclerosis with posterior column involvement
    • Shibata N, Hirano A, Kobayashi M, Siddique T. Deng H-X, Hung W-Y, Kato T, Asayama K (1996) Intense superoxide dismutase-1 immunoreactivity in intracytoplasmic hyaline inclusions of familial amyotrophic lateral sclerosis with posterior column involvement. J Neuropathol Exp Neurol 55:481-490
    • (1996) J Neuropathol Exp Neurol , vol.55 , pp. 481-490
    • Shibata, N.1    Hirano, A.2    Kobayashi, M.3    Siddique, T.4    Deng, H.-X.5    Hung, W.-Y.6    Kato, T.7    Asayama, K.8
  • 185
    • 0028059841 scopus 로고
    • Expression of a ubiquitous, cross-reactive homologue of the mouse β-amyloid precursor protein (APP)
    • Slunt HH, Thinakaran G, von Koch C, Lo ACY, Tanzi RE, Sisodia SS (1994) Expression of a ubiquitous, cross-reactive homologue of the mouse β-amyloid precursor protein (APP). J Biol Chem 269:2637-2644
    • (1994) J Biol Chem , vol.269 , pp. 2637-2644
    • Slunt, H.H.1    Thinakaran, G.2    Von Koch, C.3    Lo, A.C.Y.4    Tanzi, R.E.5    Sisodia, S.S.6
  • 186
    • 0028891759 scopus 로고
    • Nucleotide sequence of the chromosome 14-encoded S182 cDNA and revised secondary structure prediction
    • Slunt HH, Thinakaran G, Lee MK, Sisodia SS (1995) Nucleotide sequence of the chromosome 14-encoded S182 cDNA and revised secondary structure prediction. Amyloid: Int J Exp Clin Invest 2:188-190
    • (1995) Amyloid: Int J Exp Clin Invest , vol.2 , pp. 188-190
    • Slunt, H.H.1    Thinakaran, G.2    Lee, M.K.3    Sisodia, S.S.4
  • 188
    • 0001294843 scopus 로고
    • Unusual form of cerebellar ataxia. Combined dentato-rubral and pallido-Luysian degeneration
    • Smith JK, Gonda VE, Malamud N (1958) Unusual form of cerebellar ataxia. Combined dentato-rubral and pallido-Luysian degeneration. Neurology 8:205-209
    • (1958) Neurology , vol.8 , pp. 205-209
    • Smith, J.K.1    Gonda, V.E.2    Malamud, N.3
  • 192
    • 0028577208 scopus 로고
    • Immunohistochemical evidence for apoptosis in Alzheimer's disease
    • Su JH, Anderson AJ, Cummings BJ, Cotman CW (1994) Immunohistochemical evidence for apoptosis in Alzheimer's disease. Neuroreport 5:2529-2533
    • (1994) Neuroreport , vol.5 , pp. 2529-2533
    • Su, J.H.1    Anderson, A.J.2    Cummings, B.J.3    Cotman, C.W.4
  • 193
    • 0023680089 scopus 로고
    • Hereditary dentatorubral-pallidoluysian atrophy: Clinical and pathologic variants in a family
    • Takahashi H, Ohama E, Naito H, Takeda S, Nakashima S, Makifuchi T, Ikuta F (1988) Hereditary dentatorubral-pallidoluysian atrophy: clinical and pathologic variants in a family. Neurology 38:1065-1070
    • (1988) Neurology , vol.38 , pp. 1065-1070
    • Takahashi, H.1    Ohama, E.2    Naito, H.3    Takeda, S.4    Nakashima, S.5    Makifuchi, T.6    Ikuta, F.7
  • 194
    • 0028245444 scopus 로고
    • Forward and reverse genetic approaches to behavior in the mouse
    • Takahashi JS, Pinto LH, Hotz Vitaterna M (1994) Forward and reverse genetic approaches to behavior in the mouse. Science 264:1724-1733
    • (1994) Science , vol.264 , pp. 1724-1733
    • Takahashi, J.S.1    Pinto, L.H.2    Hotz Vitaterna, M.3
  • 195
    • 0023850791 scopus 로고
    • Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease
    • Tanzi RE, McClatchey Al, Lampert ED, Villa-Komaroff L, Gusella JF, Neve RL (1988) Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease. Nature 331:528-530
    • (1988) Nature , vol.331 , pp. 528-530
    • Tanzi, R.E.1    McClatchey, Al.2    Lampert, E.D.3    Villa-Komaroff, L.4    Gusella, J.F.5    Neve, R.L.6
  • 196
    • 0025987048 scopus 로고
    • Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
    • Terry RD, Masliah E, Salmon DP, Butters N, DeTeresa R, Hill R, Hansen LA, Katzman R (1991) Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 30:572-580
    • (1991) Ann Neurol , vol.30 , pp. 572-580
    • Terry, R.D.1    Masliah, E.2    Salmon, D.P.3    Butters, N.4    DeTeresa, R.5    Hill, R.6    Hansen, L.A.7    Katzman, R.8
  • 198
    • 0029942495 scopus 로고    scopus 로고
    • Metabolism of the "Swedish" APP variant in Neuro2A (N2a) cells. evidence that cleavage at the "β-secretase" site occurs in the Golgi apparatus
    • Thinakaran G, Teplow DB, Siman R, Greenberg B, Sisodia SS (1996b) Metabolism of the "Swedish" APP variant in Neuro2A (N2a) cells. evidence that cleavage at the "β-secretase" site occurs in the Golgi apparatus J Biol Chem 271:9390-9397
    • (1996) J Biol Chem , vol.271 , pp. 9390-9397
    • Thinakaran, G.1    Teplow, D.B.2    Siman, R.3    Greenberg, B.4    Sisodia, S.S.5
  • 199
    • 0019353236 scopus 로고
    • Cell loss in locus ceruleus in senile dementia of Alzheimer type
    • Tomlinson BE, Irving D, Blessed G (1981) Cell loss in locus ceruleus in senile dementia of Alzheimer type. J Neurol Sci 49:419-428
    • (1981) J Neurol Sci , vol.49 , pp. 419-428
    • Tomlinson, B.E.1    Irving, D.2    Blessed, G.3
  • 202
    • 0029966363 scopus 로고    scopus 로고
    • Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions
    • Tu P-H, Raju P, Robinson KA, Gurney ME, Trojanowski JQ, Lee VM-Y (1996) Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions. Proc Natl Acad Sci USA 93:3155-3160
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3155-3160
    • Tu, P.-H.1    Raju, P.2    Robinson, K.A.3    Gurney, M.E.4    Trojanowski, J.Q.5    Lee, V.M.-Y.6
  • 207
    • 0028213984 scopus 로고
    • Autosomal-dominant Dentatorubropallidoluysian atrophy in the United Kingdom
    • Warner TT, Lennox GG, Janota I, Harding AE (1994) Autosomal-dominant Dentatorubropallidoluysian atrophy in the United Kingdom. Mov Disord 9:289-296
    • (1994) Mov Disord , vol.9 , pp. 289-296
    • Warner, T.T.1    Lennox, G.G.2    Janota, I.3    Harding, A.E.4
  • 208
    • 0029921128 scopus 로고    scopus 로고
    • The expanding world of trinucleotide repeats
    • Warren ST (1996) The expanding world of trinucleotide repeats. Science 271.1374-1375
    • (1996) Science , vol.271 , pp. 1374-1375
    • Warren, S.T.1
  • 210
    • 0028146969 scopus 로고
    • Lipoproteins, neurobiology, and Alzheimer's disease: Structure and function of apolipoprotein e
    • Weisgraber KH, Pitas RE, Mahley RW (1994) Lipoproteins, neurobiology, and Alzheimer's disease: structure and function of apolipoprotein E. Curr Opin Struct Biol 4:507-515
    • (1994) Curr Opin Struct Biol , vol.4 , pp. 507-515
    • Weisgraber, K.H.1    Pitas, R.E.2    Mahley, R.W.3
  • 211
    • 0028122463 scopus 로고
    • Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease
    • West MJ, Coleman PD, Flood DG, Troncoso JC (1994) Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease. Lancet 344:769-772
    • (1994) Lancet , vol.344 , pp. 769-772
    • West, M.J.1    Coleman, P.D.2    Flood, D.G.3    Troncoso, J.C.4
  • 215
  • 216
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    • Wong PC, Pardo CA, Borchelt DR, Lee MK, Copeland NG, Jenkins NA, Sisodia SS, Cleveland DW, Price DL (1995) An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 14:1105-1116
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1    Pardo, C.A.2    Borchelt, D.R.3    Lee, M.K.4    Copeland, N.G.5    Jenkins, N.A.6    Sisodia, S.S.7    Cleveland, D.W.8    Price, D.L.9
  • 218
    • 0029896354 scopus 로고    scopus 로고
    • Mechanisms of neuronal degeneration in Alzheimer's disease
    • Yankner BA (1996) Mechanisms of neuronal degeneration in Alzheimer's disease Neuron 16:921-932
    • (1996) Neuron , vol.16 , pp. 921-932
    • Yankner, B.A.1
  • 219
    • 0026779680 scopus 로고
    • Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursor
    • Yoshikawa K, Aizawa T, Hayashi Y (1992) Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursor. Nature 359:64-67
    • (1992) Nature , vol.359 , pp. 64-67
    • Yoshikawa, K.1    Aizawa, T.2    Hayashi, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.