Amino terminal region of acute phase, but not constitutive, serum amyloid A (apoSAA) specifically binds and transports cholesterol into aortic smooth muscle and HepG2 cells

Journal of Lipid Research

Volumn 37, Issue 10, 1996, Pages 2109-2116

  Liang, Jun Shan ^a   Schreiber, Barbara M ^a   Salmona, Mario ^b   Phillip, Geraldine ^a   Gonnerman, Wayne A ^a   De Beer, Frederick C ^c   Sipe, Jean D ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

estradiol; lipoproteins; serum amyloid A isoforms; vitamin D

Indexed keywords

CHOLESTEROL; ESTRADIOL; LIPOPROTEIN; SERUM AMYLOID A; VITAMIN D;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; AORTA; ARTICLE; ATHEROSCLEROSIS; CELL STRAIN HEPG2; CHOLESTEROL TRANSPORT; HUMAN; HUMAN CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; RABBIT; VASCULAR SMOOTH MUSCLE;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, NEWBORN; AORTA; BINDING SITES; BIOLOGICAL TRANSPORT; CELL LINE; CHOLESTEROL; ESTRADIOL; HUMANS; LIVER; MUSCLE, SMOOTH, VASCULAR; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RABBITS; RECOMBINANT PROTEINS; SERUM AMYLOID A PROTEIN; VITAMIN D;

EID: 0029910905     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Husby, G., G. Marhaug, B. Dowton, K. Sletten, and J. D. Sipe. 1992. Serum amyloid A (SAA): biochemistry, genetics and the pathogenesis of AA amyloidosis. Amyloid. 1: 119-137.
2. Whitehead, A. S., M. C. de Beer, D. M. Steel, M. Rits, J. M. Lelia, W. S. Lane, and F. C. de Beer. 1992. Identification of novel members of the serum amyloid A protein superfamily as constitutive apolipoproteins of high density lipoprotein. J. Biol. Chem. 267: 3862-3867.
3. Meek, R. L., S. Urieli-Shoval, and E. P. Benditt. 1994. Expression of apolipoprotein serum amyloid A mRNA in human atherosclerotic lesions and cultured vascular cells: implications for serum amyloid A function. Proc. Natl. Acad. Sci. USA. 91: 3186-3190.
4. 3 cholesterol, apoA-I and apoA-II, and increased risk of myocardial infarction. Circulation. 85: 22-29.
5. Stamfer, M. J., F. M. Sacks, S. Salvini, W. C. Willet, and C. H. Hennekens. 1991. A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction. N. Engl. J. Med. 325: 373-381.
6. Fielding, C. J., V. G. Shore, and P. D. Fielding. 1972. A protein cofactor of lecithin:cholesterol acyltransferase. Biochem. Biophys. Res. Commun. 46: 1943-1949.
7. Liang, J. S., and J. D. Sipe. 1995. Recombinant human serum amyloid A (apoSAAp) binds cholesterol and modulates cholesterol flux. J. Lipid Res. 36: 37-46.
8. 4) as an apolipoprotein. J. Lipid Res. 36: 526-533.
9. Schreiber, B. M., H. V. Jones, P. Toselli, and C. Franzblau. 1992. Long term treatment of neonatal aortic smooth muscle cells with βVLDL induces cholesterol accumulation. Atherosclerosis. 95: 201-210.
10. Garnier, J., D. J. Osguthorpe, and B. Robson. 1978. Analysis of accuracy and implications of simple methods for predicting the secondary structure of globular proteins. J. Mol. Biol. 120: 97-120.
11. 1. Presumptive identification of calcium and lipid binding sites. Mol. Biol. Med. 3: 387-407.
12. Westermark, G. T., U. Engstrom, and P. Westermark. 1992. The N-terminal segment of protein AA determines its fibrillogenic property. Biochem. Biophys. Res. Commun. 182: 27-33.
13. 3) to rabbit fibroblasts. Amyloid. 2: 83-91.
14. Benditt, E. P., and N. Eriksen. 1977. Amyloid protein SAA is associated with high density lipoprotein from human serum. Proc. Natl. Acad. Sci. USA. 74: 4025-4028.
15. Bausserman, L. L. 1986. SAA kinetics in animals. In Amyloidosis. J. Marrink, and M. H. van Rijswijk, editors. Kluwer Academic Publishers, Dordrecht, The Netherlands. 337-340.
16. Gollaher, C. J., and L. L. Bausserman. 1990. Hepatic catabolism of serum amyloid A during an acute phase response and choronic inflammation. Proc. Soc. Exp. Biol. Med. 194: 245-250.
17. Badalato, R., J. M. Ming, W. J. Murphy, A. R. Lloyd, D. F. Michiel, L. L. Bausserman, D. J. Kelvin, and J. J. Oppenheim. 1994. Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes. J. Exp. Med. 180: 203-209.
18. Bretscher, M. S., and S. Munro. 1993. Cholesterol and the Golgi apparatus. Science. 261: 1280-1281.
19. Segrest, J. P., H. J. Pownall, R. L. Jackson, G. G. Glenner, and P. S. Pollock. 1976. Amyloid A: amphipathic helixes and lipid binding. Biochemistry. 15: 3187-3191.
20. Coetzee, G. A., A. F. Strachan, D. R. van der Westhuyzen, H. C. Hoppe, M. S. Jeenah, and F. C. de Beer. 1986. Serum amyloid A-containing human high density lipoprotein 3. J. Biol. Chem. 261: 9644-9651.