Recognition of mucin by the adhesin-flagellar system of Pseudomonas aeruginosa

American Journal of Respiratory and Critical Care Medicine

Volumn 154, Issue 4 II SUPPL., 1996, Pages

  Ramphal, Reuben ^a,b   Arora, Shiwani K ^a   Ritchings, Bruce W ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; MUCIN;

BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIUM ADHERENCE; CONFERENCE PAPER; FLAGELLUM; GENE CONTROL; HUMAN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PSEUDOMONAS AERUGINOSA; RESPIRATORY TRACT INFECTION;

EID: 0029910879     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm/154.4_pt_2.s170     Document Type: Conference Paper

References (32)

1. Simel, D. L., J. P. Mastin, C. P. Pratt, C. L. Wisseman, J. D. Shelburne, and A. Spock. 1984. Scanning electron microscopic study of the airways in normal children and in patients with cystic fibrosis and other lung diseases. Pediatr. Pathol. 2:47-64.
2. Jeffrey, P. K., and A. P. R. Brain. 1988. Surface morphology of human airway mucosa: normal, carcinoma or cystic fibrosis. Scanning Microsc. 2:345-351.
3. Baltimore, R. S., C. D. C. Christie, and G. J. Smith. 1989. Immunohistopathologic localization of Pseudomonas aeruginosa in lungs from patients with cystic fibrosis. Am. Rev. Respir. Dis. 140:1650-1661.
4. Beachey, E. H. 1981. Bacterial adherence: adhesin-receptor interactions mediating attachment of bacteria to mucosal surfaces. J. Infect. Dis. 143:325-345.
5. Reid, L. M., and K. R. Bhaskar. 1989. Macromolecular and lipid constituents of bronchial epithelial mucus. In E. Chantier and N. A. Ratcliffe, editors. Mucus and Related Topics. Symposia of the Society for Experimental Biology. 43:201-219.
6. Lamblin, G., M. Lhermitte, A. Klein, N. Houdret, A. Scharfman, R. Ramphal, and P. Roussel. 1991. The carbohydrate diversity of human respiratory mucins: a protection of the underlying mucosa. Am. Rev. Respir. Dis. 144:S19-S24.
7. Vishwanath, S., and R. Ramphal. 1984. Adherence of Pseudomonas aeruginosa to human tracheobronchial mucin. Infect. Immun. 85: 197-202.
8. Ramphal, R., C. Carnoy, S. Fievre, J.-C. Michalski, N. Houdret, G. Lamblin, G. Strecker, and P. Roussel. 1991. Pseudomonas aeruginosa recognizes carbohydrate chains containing type 1 (Ga1β1-3G1-cNAc) or type 2 (Ga1β1-4GlcNAc) disaccharide units. Infect. Immun. 59:700-704.
9. Vasil, M. L. 1986. Pseudomonas aeruginosa: biology, mechanisms of virulence, epidemiology. J. Pediatr. 108:800-805.
10. Woods, D. W., D. C. Straus, W. J. Johanson, V. K. Berry, and J. A. Bass. 1980. Role of pili in adherence of Pseudomonas aeruginosa to mammalian buccal epithelial cells. Infect. Immun. 29:1146-1151.
11. Ramphal, R., J. C. Sadoff, M. Pyle, and J. D. Sillipigni. 1984. Role of pili in adherence of Pseudomonas aeruginosa to injured tracheal epithelium. Infect. Immun. 29:1146-1151.
12. Ramphal, R., C. Guay, and G. B. Pier. 1986. Pseudomonas aeruginosa adhesins for tracheobronchial mucin. Infect. Immun. 55:600-603.
13. Ramphal, R., and G. B. Pier. 1985. Role of Pseudomonas aeruginosa mucoid exopolysaccharde in adherence to tracheal cells. Infect. Immun. 47:1-4.
14. Gupta, S. K., R. S. Berk, S. Masinick, and L. D. Hazlett. 1994. Pili and lipopolysaccharide of Pseudomonas aeruginosa blind to the glycolipid asialo GM1. Infect. Immun. 62:4572-4579.
15. Carnoy, C., A. Scharfman, E. Van Brussel, G. Lamblin, R. Ramphal, and P. Roussel. 1994. Pseudomonas aeruginosa outer membrane adhesins for human respiratory mucus glycoproteins. Infect. Immun. 62:1896-1900.
16. Reddy, M. S. 1992. Human tracheobronchial mucin: purification and binding to Pseudomonas aeruginosa. Infect. Immun. 60:1530-1535.
17. Ramphal, R., L. Koo, K. S. Ishimoto, P. A. Totten, J. C. Lara, and S. Lory. 1991. Adhesion of Pseudomonas aeruginosa pilin-deficient mutants to mucin. Infect. Immun. 59:1307-1311.
18. Totten, P. A., J. C. Lara, and S. Lory. 1990. The rponN gene product of Pseudomonas aeruginosa is required for expression of diverse genes, including the flagellin gene. J. Bacteriol. 172:389-396.
19. Saiman, L., K. Ishimoto, S. Lory, and A. Prince. 1990. The effect of piliation and exoproduct expression on the adherence of Pseudomonas aeruginosa to respiratory epithelial monolayers. J. Infect. Dis. 161:541-548.
20. Chi, E., R. Mehl, D. Nunn, and S. Lory. 1991. Interaction of Pseudomonas aeruginosa with A549 pneumocyte cells. Infect. Immun. 59: 949-954.
21. Simpson, D. A., R. Ramphal and S. Lory. 1992. Genetic analysis of Pseudomonas aeruginosa adherence: distinct genetic loci control attachment to epithelial cells and mucins. Infect. Immun. 60:3771-3779.
22. Totten, P. A., and S. Lory. 1990. Characterization of the type a flagellin gene from Pseudomonas aeruginosa PAK. J. Bacterial. 172:7188-7199.
23. Starnbach, M. N., and S. Lory. 1992. The fliA (rpoF) gene of Pseudomonas aeruginosa encodes an alternative sigma factor required for flagellin synthesis. Mol. Microbiol. 6:459-469.
24. Blair, D. F. 1995. How bacteria sense and swim. Annu. Rev. Microbiol. 49:489-522.
25. 34-dependent flagellar gene family in Caulobacter crescentus by the transcriptional activator F1bD. J. Bacteriol. 177:3241-3250.
26. Simpson, D. A., R. Ramphal, and S. Lory. 1995. Characterization of Pseudomonas aeruginosa fliO, a regulatory gene of flagellar biosynthesis and adherence. Infect. Immun. 63:2950-2957.
27. Arora, S. K., B. W. Ritchings, E. Almira, S. Lory, and R. Ramphal. 1996. Cloning and characterization of Pseudomonas aeruginosa fliF gene, is necessary for flagellar assembly and bacterial adherence to mucin. Infect. Immun. 64:2130-2136.
28. Ritchings, B. W., E. C. Almira, S. Lory, and R. Ramphal. 1995. Cloning and phenotypic characterization of fleS and fleR, new response regulators of Pseudomonas aeruginosa which regulate motility and adhesion to mucin. Infect. Immun. 63:4868-4876.
29. 54 bacterial enhancer-binding protein family: mechanism of action and phylogenetic relationship of their functional domains. J. Bacteriol. 175:6067-6074.
30. Stock, J. B., A. M. Stock, and J. M. Mottonen. 1990. Signal transduction in bacteria. Nature 344:395-400.
31. 1) and activates sigma-54 dependent flagellar gene promoters. Proc. Natl. Acad. Sci. U.S.A. 87:2369-2373.
32. Friedman, D. I. 1988. Integration host factor: a protein for all reasons. Cell 55:545-554.