In situ localization of tissue factor in human atherosclerotic plaques by binding of digoxigenin-labeled factors VIIa and X

Laboratory Investigation

Volumn 75, Issue 4, 1996, Pages 451-461

  Thiruvikraman, Singanallore V ^a   Guha, Arabinda ^a   Roboz, John ^a   Taubman, Mark B ^a   Nemerson, Yale ^a   Fallon, John T ^a,b  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 7A; DIGOXIGENIN; THROMBOPLASTIN;

ARTERY MUSCLE; ARTICLE; ATHEROSCLEROTIC PLAQUE; ENDOTHELIUM CELL; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; STAINING; THROMBOGENESIS; THROMBOSIS; TISSUE DISTRIBUTION;

ANIMALS; ARTERIES; ARTERIOSCLEROSIS; CORONARY VESSELS; DIGOXIGENIN; FACTOR VIIA; FACTOR X; HUMANS; IMMUNOHISTOCHEMISTRY; PROTEIN BINDING; SKIN; STAINING AND LABELING; THROMBOPLASTIN;

EID: 0029910861     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Annex BH, Denning JH, Channon KM, Sketch MH, Stack RS, Morrissey JH, and Peters KG (1995). Differential expression of tissue factor protein in directional atherectomy specimens from patients with stable and unstable coronary syndromes. Circulation 91:619-622.
2. Bach RR (1988). Initiation of coagulation by tissue factor. Crit Rev Biochem 23:339-368.
3. Bach R, Gentry R, and Nemerson Y (1986). Factor VII binding to tissue factor in reconstituted phospholipid vesicles: Induction of cooperativity by phosphatidylserine. Biochemistry 25:4007-4020.
4. Butenas S, Lawson JH, Kalafatis M, and Mann KG (1994). Cooperative interaction of divalent metal ions, substrate, and tissue factor with factor VIIa. Biochemistry 33:3449-3456.
5. Carson SD, Ross SE, and Bach Guha A (1987). An inhibitory monoclonal antibody against human tissue factor. Blood 70:490-493.
6. Contrino J, Hair GA, Schmeizl MA, Rickles FR, and Kreutzer DL (1994). In situ characterization of antigenic and functional tissue factor expression in human tumors utilizing monoclonal antibodies and recombinant factor VIIa as probes. Am J Pathol 145:1315-1322.
7. Drake TA, Morrissey JH, and Edgington TS (1989). Selective cellular expression of tissue factor in human tissues. Am J Pathol 134:1087-1097.
8. Fernandez-Ortiz A, Badimon JJ, Falk E, Fuster V, Meyer VB, Mailhac A, Weng D, Shah PK, and Badimon L (1994). Characterization of the relative thrombogenicity of atherosclerotic plaque components: Implications for consequences of plaque rupture. JACC 23:1562-1569.
9. Fleck RA, Rao LVM, Rapaport SI, and Varki N (1990). Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody. Thromb Res 57:765-781.
10. Fuster V, Badimon L, Cohen M, Ambrose JA, Badimon JJ, and Chesebro JH (1988). Insights into the pathogenesis of acute ischemic syndromes. Circulation 77:1213-1220.
11. Gertz SD, Gimble LW, Ragosta M, Roberts WC, Haber HL, Powers ER, Perez LS, and Sarembock IJ (1993). Response of femoral arteries of cholesterol-fed rabbits to balloon angioplasty with or without laser: Emphasis on the distribution of foam cells. Exp Mol Pathol 59:225-243.
12. Härtig W, Hausen D, Brauer K, Arendt T, Bigl V, and Brückner G (1994). Digoxigenin-tagged anti-GFAP and multiple labeling of human glia, vessels and β-amyloid. Clin Neurosci Neuropathol 5:573-576.
13. Henrikson KP, Hall ES, and Lin Y (1994). Cellular localization of tissue factor and prothrombin in the estrogen-treated immature rat uterus. Biol Reprod 50:1145-1150.
14. Katz SS, Shipley GG, and Small DM (1976). Physical chemistry of the lipids of human atherosclerotic lesions. Demonstration of a lesion intermediate between fatty streaks and advanced plaques. J Clin Invest 58:200-211.
15. Landers SC, Gupta M, and Lewis JC (1994). Ultrastructural localization of tissue factor on monocyte-derived macrophages and macrophage foam cells associated with atherosclerotic lesions. Virchows Arch 425:49-54.
16. Mackman N (1995). Regulation of the tissue factor gene. FASEB J 9:883-889.
17. Marmur JD, Thiruvikraman SV, Fyfe BS, Guha A, Sharma SK, Ambrose JA, Fallon JT, Nemerson Y, and Taubman MB (in press, 1996). The identification of active tissue factor in human coronary atheroma. Circulation.
18. Maynard JR, Heckman CA, Pitlick FA, and Nemerson Y (1975). Association of tissue factor with the surface of cultured cells. J Clin Invest 55:814-824.
19. Miletich JP, Broze GJ, and Majerus PW (1981). Purification of human coagulation factors II, IX, and X using sulfated dextran beads. Methods Enzymol 80:221-228.
20. Nawroth PP, Stern DM, and Kisiel W (1985). Cellular requirements for tissue factor generation by bovine aortic endothelial cells in culture. Thromb Res 40:677-691.
21. Nemerson Y (1988). Tissue factor and hemostasis. Blood 71:1-8.
22. Nemerson Y (1992). The tissue factor pathway of blood coagulation. Semin Hematol 29:170-176.
23. Nemerson Y and Gentry RD (1986). An ordered addition, essential activation model of the tissue factor pathway of coagulation: Evidence for a conformational change. Biochemistry 25:4020-4033.
24. Roboz J, Yu Q, Meng A, and van Soest R (1994). On-line buffer removal and fraction selection in gradient capillary high-performance liquid chromatography prior to electrospray mass spectrometry of peptides and proteins. Rapid Commun Mass Spectrom 8:621-626.
25. Stary HC, Chandler AB, Dinsmor RE, Fuster V, Glagov S, Insull W Jr, Rosenfeld ME, Schwartz CJ, Wagner WD, and Wisssler RW (1995). A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation 92:1355-1374.
26. 2+ mobilization and protein kinase C activation. J Clin Invest 91:547-552.
27. Tipping PG, Malliaros J, and Holdsworth SR (1989). Procoagulant activity expression by macrophages from atheromatous vascular plaques. Atherosclerosis 79:237-243.
28. van Zanten GH, de Graaf S, Slootweg PJ, Heijnen HF, Connolly TM, de Groot PG, and Sixma JJ (1994). Increased platelet deposition on atherosclerotic coronary arteries. J Clin Invest 93:615-632.
29. Waxman EJ, Ross BA, Laue TM, Guha A, Thiruvikraman SV, Lin TC, Konigsberg WH, and Nemerson Y (1992). Tissue factor and its extracellular soluble domain: The relationship between intermolecular association with factor VIIa and enzymatic activity of the complex. Biochemistry 31:3998-4003.
30. Wilcox JN, Smith KM, Schwartz SM, and Gordon D (1989). Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque. Proc Natl Acad Sci USA 86:2839-2843.