Circadian changes in anxiolysis-related behavior of Syrian hamsters. Correlation with hypothalamic GABA release

Biological Rhythm Research

Volumn 27, Issue 3, 1996, Pages 365-373

  Yannielli, Paola C ^a   Kanterewicz, Beatriz I ^a   Cardinali, Daniel P ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

anxiolysis; Circadian rhythms; exploratory behavior; flumazenil; GABA release; preoptic medial basal hypothalamus

Indexed keywords

EID: 0029910241     PISSN: 09291016     EISSN: None     Source Type: Journal    
DOI: 10.1076/brhm.27.3.365.12967     Document Type: Conference Paper

References (32)

1. ACUÑA CASTROVIEJO, D., LOWENSTEIN, P.R., ROSENSTEIN, R. and CARDINALI, D.P. (1986a): Diurnal variations of benzodiazepine receptor binding in rat cerebral cortex: Disruption by pinealectomy. J. Pineal Res., 3: 101-109.
2. ACUÑA CASTROVIEJO, D., ROSENSTEIN, R., ROMEO, H.E. and CARDINALI, D.P. (1986b): Changes in gamma aminobutyric acid high affinity binding to cerebral cortex membranes after pinealectomy or melatonin administration to rats. Neuroendocrinology, 43: 24-31.
3. AGUILAR-ROBLERO, R., VERDUZCO-CARBAJAL, L., RODRIGUEZ, C., MENDES-FRANCO, J., MORAN, J. and PERES DE LA MORA, M. (1993): Circadian rhythmicity in the GABAergic system in the suprachiasmatic nuclei of the rat. Neurosci. Lett., 157: 199-202.
4. BARKAI, A.I., POTEGAL, M. and KOWALIK, S. (1985): Decline of GABA uptake in the hamster preoptic area following light onset. J. Neurochem., 44: 987-989.
5. BIGGIO, G., CONCAS, A., CORDA, M.G., GIORGI, O., SANNA, E. and SERRA, M. (1990): Gabaergic and dopaminergic transmission in the rat cerebral cortex: Effect of stress, anxiolytic and anxiogenic drugs. Pharmac. Ther., 48: 121-142.
6. CARDINALI, D.P. (1995): Sources and physiological role of melatonin in mammals. In: The Melatonin Receptor, (Dubocovich, M.L., Ed) Harwood Academic Publishers, Chur, Switzerland, in press.
7. CARDINALI, D. P., ROSENSTEIN, R. E., KANTEREWICZ, B. A., CUTRERA, R., FAILLACE, M. P., DELLA MAGGIORE, V. and YANNIELLI, P. C. (1995): Neural mechanisms involved in the chronobiological activity of melatonin. Neuroendocrinol. Lett., 17: 103-114.
8. CASANUEVA, F., APUD, J.A., MASOTTO, C., COCCHI, D., LOCATELLI, V., RACAGNI, G. and MULLER, E.E. (1984): Daily fluctuations in the activity of the tuberoinfundibular GABAergic system and prolactin levels. Neuroendocrinology, 39: 367-370.
9. CATTABENI, F., MAGGI, A., MONDUZZI, M., DE ANGELLIS, L. and RACAGNI, G. (1978): GABA: circadian fluctuations in rat hypothalamus. J. Neurochem., 31: 565-567.
10. FILE, S.E. and HYDE, J.R. (1979): A test of anxiety that distinguishes between the actions of benzodiazepines and those of other minor tranquilisers and of stimulants. Pharmacol. Biochem. Behav., 11: 65-69.
11. FILE, S.E., ZANGROSSI, H. and ANDREWS, N. (1993a): Social interaction and elevated plusmaze test: Changes in release and uptake of 5HT and GABA. Neuropharmacology, 32: 217-221.
12. FILE, S.E., ZANGROSSI, H., VIANA, M. and GRAEFF, F. (1993b): Trial 2 in the elevated plus maze: A different form of fear? Psychopharmacology, 11: 491-494.
13. GOLOMBEK, D.A. and CARDINALI, D.P. (1993): Melatonin accelerates re-entrainment after phase advance of the light-dark cycle in Syrian hamsters. Antagonism by flumazenil. Chronobiol. Int., 10: 435-441.
14. GOLOMBEK, D.A., ESCOLAR, E., BURIN, L., DE BRITO SANCHEZ, M. and CARDINALI, D.P. (1991a): Time-dependent melatonin analgesia in mice: Inhibition by opiate or benzodiazepine antagonism. Eur. J. Pharmacol., 194: 25-30.
15. GOLOMBEK, D., ESCOLAR, E. and CARDINALI, D.P. (1991b): Melatonin-induced depression of locomotor activity in hamsters. Time-dependency and inhibition by the central-type benzodiazepme antagonist Ro 15-1788. Physiol. Behav., 49: 1091-1098.
16. GOLOMBEK, D.A., FERNANDEZ DUQUE, D., DE BRITO, SANCHEZ, M.G., BURIN, L. and CARDINALI, D.P. (1992): Time-dependent anticonvulsant activity of melatonin in hamsters. Eur. J. Pharmacol., 210: 253-258.
17. GOLOMBEK, D.A., MARTINI, M. and CARDINALI, D.P. (1993): Melatonin as an anxiolytic in rats: Time-dependence and interaction with the central gabaergic system. Eur. J. Pharmacol., 237: 231-236.
18. HANDLET, S. L. and MCBLANE, J. W. (1993): An assessment of the elevated X-maze for studying anxiety and anxiety-modulating drugs. J. Pharmacol. Toxicol. Meth., 29: 129-138.
19. KANTEREWICZ, B.I., GOLOMBEK, D.A., ROSENSTEIN, R.E. and CARDINALI, D.P. (1993): Diurnal changes of GABA turnover rate in brain and pineal gland of Syrian hamsters. Brain Res. Bull., 31: 661-666.
20. KANTEREWICZ, B.I., ROSENSTEIN, R.E., GOLOMBEK, D.A., YANNIELLI, P.C. and CARDINALI, D.P. (1995): Daily variations in GABA receptor function in Syrian hamster cerebral cortex. Neurosci. Lett., in press.
21. LIOU, S.Y., SHIBATA, S., ALBERS, H.E. and UKEI, S. (1990): Effects of GABA and anxiolytics on the single unit discharge of suprachiasmatic neurons in rat hypothalamic slices. Brain Res. Bull., 25: 103-107.
22. MASSON, R., BIELLO, S.M. and HARRINGTON, M.E. (1991): The effects of GABA andbenzodiazepines on neurons in the suprachiasmatic nucleus (SCN) of Syrian hamsters. Brain Res., 552: 53-57.
23. MOORE, R.Y. and SPEH, J.C. (1993): GABA is the principal neurotransmitter of the circadian system. Neurosci. Lett., 150: 112-116.
24. PELLOW, S. and FILE, S.E. (1986): Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus maze: A novel test of anxiety in the rat. Pharmacol. Biochem. Behav., 24: 525-529.
25. ROSENSTEIN, R.E. and CARDINALI, D.P. (1986): Melatonin increases in vivo GABA accumulation in rat hypothalamus, cerebellum, cerebral cortex and pineal gland. Brain Res., 398: 403-406.
26. ROSENSTEIN, R.E. and CARDINALI, D.P. (1990): Central gabaergic mechanisms as targets for melatonin activity in brain. Neurochem. Int., 17: 373-379.
27. ROSENSTEIN, R.E., CHULUYAN, H.E., PEREYRA, E. N. and CARDINALI, D.P. (1989a): Release and effect of g-aminobutyric acid (GABA) on rat pineal melatonin production in vitro. Cell. Mol. Neurobiol., 9:207-219.
28. - influx in rat hypothalamus. J. Neuroendocrinol., 1: 443-447.
29. SIEGHART, W. (1992): GABAA receptors: Ligand-gated Cl- ion channels modulated by multiple drug-binding sites. Trends Pharmacol., 13: 446-450.
30. STANKOV, B., BIELLA, B., PANARA, C., LUCINI, V., CAPSONI, S., FAUTECK, J., COZZI, B. and FRASCHINI, F. (1992): Melatonin signal transduction and mechanism of action in the central nervous system: Using the rabbit cortex as a model. Endocrinology, 130: 2152-2159.
31. YANNIELLI, P.C., KANTEREWICZ, B.I. and CARDINALI, D.P. (1996): Daily rhythms in spontaneous and diazepam-induced anxiolysis in Syrian hamsters. Pharmacol. Biochem. Behav., in press.
32. ZORUMSKY, C.F. and ISEMBERG, K.E. (1991): Insights into the structure and function of GABA-BDZ receptors: ion-channels and psychiatry. Am. J. Psychiatry, 148: 162-173.