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Volumn 16, Issue 10, 1996, Pages 771-776

Mouse myeloma cell line secreting bifunctional fusion protein RM4/IFN- τ elicits antitumor CD8 MHC class I-restricted T cells that are cytolytic in vitro and tumoricidal in vivo

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; HYBRID PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; INTERFERON; TAU INTERFERON;

EID: 0029909453     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.1996.16.771     Document Type: Article
Times cited : (14)

References (37)
  • 1
    • 0022992144 scopus 로고
    • Interferon and major histocompatibility complex genes: A model to analyze eukaryotic gene regulation
    • I. Gresser (ed.) London: Academic
    • ROS, F., COCHET, M., and FELLOUS, M. (1986). Interferon and major histocompatibility complex genes: a model to analyze eukaryotic gene regulation. In: Interferon-τ I. Gresser (ed.) London: Academic, pp. 47-87.
    • (1986) Interferon-τ , pp. 47-87
    • Ros, F.1    Cochet, M.2    Fellous, M.3
  • 2
    • 0022397554 scopus 로고
    • Induction of HLA class II antigen expression on human carcinoma cell lines by IFN-τ
    • SCHWARTZ, R., MOMBURG, F., MOLDENHAUER, G., DORKEN, B., and SCHIRRMACHER, V. (1985). Induction of HLA class II antigen expression on human carcinoma cell lines by IFN-τ. Int. J. Cancer 35, 245-252.
    • (1985) Int. J. Cancer , vol.35 , pp. 245-252
    • Schwartz, R.1    Momburg, F.2    Moldenhauer, G.3    Dorken, B.4    Schirrmacher, V.5
  • 3
    • 0026547830 scopus 로고
    • Interferon-induced increase in sensitivity of ovarian cancer targets to lysis by lymphokine-activated killer cells: Selective effects on HER2/neu expressing cells
    • FADY, C., GARDNER, A., GERA, J., and LICHTENSTEIN, A. (1992). Interferon-induced increase in sensitivity of ovarian cancer targets to lysis by lymphokine-activated killer cells: selective effects on HER2/neu expressing cells. Cancer Res. 52, 764-769.
    • (1992) Cancer Res. , vol.52 , pp. 764-769
    • Fady, C.1    Gardner, A.2    Gera, J.3    Lichtenstein, A.4
  • 4
    • 0021964067 scopus 로고
    • Reversal of oncogenesis by the expression of a major histocompatibility complex class I gene
    • TANAKA, K., ISSELBACHER, K., KHOURY, G., and JAY, G. (1985). Reversal of oncogenesis by the expression of a major histocompatibility complex class I gene. Science 228, 26-29.
    • (1985) Science , vol.228 , pp. 26-29
    • Tanaka, K.1    Isselbacher, K.2    Khoury, G.3    Jay, G.4
  • 5
    • 0023125999 scopus 로고
    • Recombinant interferon enhances monoclonal antibody-targeting of carcinoma lesions in vivo
    • GREINER, J., GUADAGNI, F., NOGUCHI, P., PESTKA, S., COLCHER, D., FISHER, P., and SCHLOM, J. (1987). Recombinant interferon enhances monoclonal antibody-targeting of carcinoma lesions in vivo. Science 235, 895-898.
    • (1987) Science , vol.235 , pp. 895-898
    • Greiner, J.1    Guadagni, F.2    Noguchi, P.3    Pestka, S.4    Colcher, D.5    Fisher, P.6    Schlom, J.7
  • 6
    • 0024393806 scopus 로고
    • Modulation of carcinoembryonic antigen messenger RNA levels in human colon carcinoma cells by recombinant human τ-interferon
    • KANTOR, J., TRAN, R., GREINER, J., PESTKA, S., FISHER, P., SHIVELY, J., and SCHLOM, J. (1989). Modulation of carcinoembryonic antigen messenger RNA levels in human colon carcinoma cells by recombinant human τ-interferon. Cancer Res. 49, 2651-2655.
    • (1989) Cancer Res. , vol.49 , pp. 2651-2655
    • Kantor, J.1    Tran, R.2    Greiner, J.3    Pestka, S.4    Fisher, P.5    Shively, J.6    Schlom, J.7
  • 7
    • 0023162619 scopus 로고
    • Molecular transduction mechanisms by which IFN-gamma and other signals regulate macrophage development
    • ADAMS, D., and HAMILYON, T. (1987). Molecular transduction mechanisms by which IFN-gamma and other signals regulate macrophage development. Immunol. Rev. 97, 5-19.
    • (1987) Immunol. Rev. , vol.97 , pp. 5-19
    • Adams, D.1    Hamilyon, T.2
  • 9
    • 0023917090 scopus 로고
    • Differential effects of recombinant interferon alpha, beta and gamma on induction of human lymphokine-activated killer activity
    • SONE, S., UTSUGI, T., and OGURA, T. (1988). Differential effects of recombinant interferon alpha, beta and gamma on induction of human lymphokine-activated killer activity. J. Natl. Cancer Inst. 80, 425-431.
    • (1988) J. Natl. Cancer Inst. , vol.80 , pp. 425-431
    • Sone, S.1    Utsugi, T.2    Ogura, T.3
  • 10
  • 11
    • 0024384319 scopus 로고
    • IL-2 and IFN-τ are two necessary lymphokines in the development of cytolytic T cells
    • MARASKOVSKY, E., CHEN, W., and SHORTMAN, K. (1989). IL-2 and IFN-τ are two necessary lymphokines in the development of cytolytic T cells. J. Immunol. 143, 1210-1214.
    • (1989) J. Immunol. , vol.143 , pp. 1210-1214
    • Maraskovsky, E.1    Chen, W.2    Shortman, K.3
  • 12
    • 0019308886 scopus 로고
    • Therapy of spontaneous metastases by intravenous injection of liposomes containing lymphokines
    • FIDLER, J. (1980). Therapy of spontaneous metastases by intravenous injection of liposomes containing lymphokines. Science 208, 1469-1471.
    • (1980) Science , vol.208 , pp. 1469-1471
    • Fidler, J.1
  • 13
    • 0023916449 scopus 로고
    • Adoptive immunotherapy of syngeneic murine leukemia is enhanced by the combination of recombinant IFN-τ and a tumor-specific cytotoxic T cell clone
    • DE GRAAF, P., HORAK, E., and BOOKMAN, M. (1988). Adoptive immunotherapy of syngeneic murine leukemia is enhanced by the combination of recombinant IFN-τ and a tumor-specific cytotoxic T cell clone. J. Immunol. 140, 2853-2857.
    • (1988) J. Immunol. , vol.140 , pp. 2853-2857
    • De Graaf, P.1    Horak, E.2    Bookman, M.3
  • 14
    • 0026337879 scopus 로고    scopus 로고
    • Antitumor activity of τ-interferon in ascites and solid tumor models of human ovarian cancer
    • MALIK, S., KNOWLES, R., EAST, N., LANDO, D., STAMP, G., and BALKWILL, F. Antitumor activity of τ-interferon in ascites and solid tumor models of human ovarian cancer. Cancer Res. 51, 6643-6649.
    • Cancer Res. , vol.51 , pp. 6643-6649
    • Malik, S.1    Knowles, R.2    East, N.3    Lando, D.4    Stamp, G.5    Balkwill, F.6
  • 15
    • 0026582149 scopus 로고
    • Immunological effects of treatment with sequential administration of recombinant interferon-τ and alpha in patients with metastases renal cell carcinoma during a phase I trial
    • ERNSTOFF, M., GOODING, W., NAIR, S., BAHNSON, R., MIKKETIC, L., BANNER, B., DAY, R., WHITESIDE, T., and KIRKWOOD, J. (1992). Immunological effects of treatment with sequential administration of recombinant interferon-τ and alpha in patients with metastases renal cell carcinoma during a phase I trial. Cancer Res. 52, 851-856.
    • (1992) Cancer Res. , vol.52 , pp. 851-856
    • Ernstoff, M.1    Gooding, W.2    Nair, S.3    Bahnson, R.4    Mikketic, L.5    Banner, B.6    Day, R.7    Whiteside, T.8    Kirkwood, J.9
  • 16
    • 0026576518 scopus 로고
    • The combination of τ-interferon and tumor necrosis factor causes a rapid and extensive differentiation of human neuroblastoma cells
    • PONZONI, M., CASALARO, A., LANCIOTTI, M., MONTALDO, F., and CORNAGLIA-FERRARIS, P. (1992). The combination of τ-interferon and tumor necrosis factor causes a rapid and extensive differentiation of human neuroblastoma cells. Cancer Res. 52, 931-939.
    • (1992) Cancer Res. , vol.52 , pp. 931-939
    • Ponzoni, M.1    Casalaro, A.2    Lanciotti, M.3    Montaldo, F.4    Cornaglia-Ferraris, P.5
  • 17
    • 0023888150 scopus 로고
    • Recombinant interferon alpha and gamma in combinations as treatment for metastatic renal cell carcinoma
    • QUESADA, J., EVANS, L., SAKS, S., and GUTTERMAN, J. (1988). Recombinant interferon alpha and gamma in combinations as treatment for metastatic renal cell carcinoma. J. Biol. Resp. Modif. 7, 234-239.
    • (1988) J. Biol. Resp. Modif. , vol.7 , pp. 234-239
    • Quesada, J.1    Evans, L.2    Saks, S.3    Gutterman, J.4
  • 18
    • 0021969122 scopus 로고
    • Pharmacokinetics, single dose tolerance and biological activity of recombinant gamma interferon in cancer patients
    • KURZROCK, R., ROSENBLUM, M., and SHERWIN, S. (1985). Pharmacokinetics, single dose tolerance and biological activity of recombinant gamma interferon in cancer patients. Cancer Res. 45, 2866-2871.
    • (1985) Cancer Res. , vol.45 , pp. 2866-2871
    • Kurzrock, R.1    Rosenblum, M.2    Sherwin, S.3
  • 21
    • 0025760632 scopus 로고
    • Radiotherapy in mice with yttrium-90-labeled anti-Ly1 monoclonal antibody: Therapy of the T cell lymphoma EL4
    • SCHMIDBERGER, H., BUCHSBAUM, D., BLAZAR, B., EVERSON, P., and VALLERA, D. (1991). Radiotherapy in mice with yttrium-90-labeled anti-Ly1 monoclonal antibody: therapy of the T cell lymphoma EL4. Cancer Res. 51, 1883-1890.
    • (1991) Cancer Res. , vol.51 , pp. 1883-1890
    • Schmidberger, H.1    Buchsbaum, D.2    Blazar, B.3    Everson, P.4    Vallera, D.5
  • 23
    • 0025875744 scopus 로고
    • Construction and expression of antibody-tumor necrosis factor fusion protein
    • HOOGENBOOM, H., VOLCKAERT, G., and RAUS, J. (1991). Construction and expression of antibody-tumor necrosis factor fusion protein. Mol. Immunol. 28, 1027-1037.
    • (1991) Mol. Immunol. , vol.28 , pp. 1027-1037
    • Hoogenboom, H.1    Volckaert, G.2    Raus, J.3
  • 24
    • 0029908874 scopus 로고    scopus 로고
    • Targeting gamma interferon to tumor cells by a genetically engineered bifunctional fusion protein RM4/TFN-τ
    • In press
    • XIANG, J., QI, Y., and MOYANA, T. (1996). Targeting gamma interferon to tumor cells by a genetically engineered bifunctional fusion protein RM4/TFN-τ. Hum. Antibodies Hybridomas. In press.
    • (1996) Hum. Antibodies Hybridomas
    • Xiang, J.1    Qi, Y.2    Moyana, T.3
  • 25
    • 0027016849 scopus 로고
    • Construction and characterization of a high-affinity chimeric anti-colorcctal carcinoma antibody ccM4
    • XIANG, J., MOYANA, T., KAIRA, J., HAMILTON, T., and QI, Y. (1992). Construction and characterization of a high-affinity chimeric anti-colorcctal carcinoma antibody ccM4. Mol. Biother. 4, 174-182.
    • (1992) Mol. Biother. , vol.4 , pp. 174-182
    • Xiang, J.1    Moyana, T.2    Kaira, J.3    Hamilton, T.4    Qi, Y.5
  • 26
    • 0019755391 scopus 로고
    • A convenient and rapid cytopathic effect inhibition assay for interferon
    • PHILIP, F., SARA, R., and SIDNEY, P. (1981). A convenient and rapid cytopathic effect inhibition assay for interferon. Methods Enzymol. 78, 387-394.
    • (1981) Methods Enzymol. , vol.78 , pp. 387-394
    • Philip, F.1    Sara, R.2    Sidney, P.3
  • 27
    • 0027078670 scopus 로고
    • Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecule CD28 and CTLA-4
    • CHEN, L., ASHE, S., BRADY, W., HELLSTROM, I., HELLSTROM, K., LEDBETTER, J., McGOWAN, P., and LINSLEY, P. (1992). Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecule CD28 and CTLA-4. Cell 71, 1093-1102.
    • (1992) Cell , vol.71 , pp. 1093-1102
    • Chen, L.1    Ashe, S.2    Brady, W.3    Hellstrom, I.4    Hellstrom, K.5    Ledbetter, J.6    McGowan, P.7    Linsley, P.8
  • 29
    • 0021234635 scopus 로고
    • Monoclonal antibody to murine gamma interferon inhibits lymphokine-induced antiviral and macrophage tumoricidal activities
    • SPITALNY, G., and HAVELL, E. (1984). Monoclonal antibody to murine gamma interferon inhibits lymphokine-induced antiviral and macrophage tumoricidal activities. J. Exp. Med. 159, 1560-1565.
    • (1984) J. Exp. Med. , vol.159 , pp. 1560-1565
    • Spitalny, G.1    Havell, E.2
  • 30
    • 0026544897 scopus 로고
    • Induction of cytotoxic T lymphocytes specific for a syngeneic tumor expressing the E6 oncoprotein of human papillomavirus type 16
    • CHEN, L., MIZUNO, M., SINGHAL, M., HU, S., GALLOWAY, D., HELLSTROM, I., and HELLSTROM, K. (1992). Induction of cytotoxic T lymphocytes specific for a syngeneic tumor expressing the E6 oncoprotein of human papillomavirus type 16. J. Immunol. 148, 2617-2621.
    • (1992) J. Immunol. , vol.148 , pp. 2617-2621
    • Chen, L.1    Mizuno, M.2    Singhal, M.3    Hu, S.4    Galloway, D.5    Hellstrom, I.6    Hellstrom, K.7
  • 31
    • 0025604195 scopus 로고
    • Retroviral vector-mediated τ-interferon gene transfer into tumor cells generates potent and long lasting antitumor immunity
    • GANSBACHER, B., BANNERJI, R., DANIELS, B., ZIER, K., CRONIN, K., and GILBOA, E. (1990). Retroviral vector-mediated τ-interferon gene transfer into tumor cells generates potent and long lasting antitumor immunity. Cancer Res. 50, 7820-7825.
    • (1990) Cancer Res. , vol.50 , pp. 7820-7825
    • Gansbacher, B.1    Bannerji, R.2    Daniels, B.3    Zier, K.4    Cronin, K.5    Gilboa, E.6
  • 32
    • 0024326949 scopus 로고
    • Exogenous expression of mouse interferon gamma cDNA in mouse neuroblastoma C1300 cells results in reduced tumorigenicity by augmented antitumor immunity
    • WATANABE, Y., KURIBAYASHI, K., MIYATAKE, S., NISHIHARA, K., NAKAYAMA, E., TANIYAMA, T., and SAKATA, T. (1989). Exogenous expression of mouse interferon gamma cDNA in mouse neuroblastoma C1300 cells results in reduced tumorigenicity by augmented antitumor immunity. Proc. Natl. Acad. Sci. USA 86, 9456-9460.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 9456-9460
    • Watanabe, Y.1    Kuribayashi, K.2    Miyatake, S.3    Nishihara, K.4    Nakayama, E.5    Taniyama, T.6    Sakata, T.7
  • 33
    • 0026517015 scopus 로고
    • A nonimmunogenic sarcoma transduced with the cDNA for interferon elicits CD8 T cells against the wild-type tumor: Correlation with antigen presentation capability
    • RESTIFO, N., SPIESS, P., KARP, S., MULE, J., and ROSENBERG, S. (1992). A nonimmunogenic sarcoma transduced with the cDNA for interferon elicits CD8 T cells against the wild-type tumor: correlation with antigen presentation capability. J. Exp. Med. 175, 1423-1431.
    • (1992) J. Exp. Med. , vol.175 , pp. 1423-1431
    • Restifo, N.1    Spiess, P.2    Karp, S.3    Mule, J.4    Rosenberg, S.5
  • 34
    • 0027407938 scopus 로고
    • Mechanisms of rejection induced by tumor cell targeted gene transfer of IL-2, IL-4, IL-7, TNF and IFN-τ
    • HOCK, H., DORSCH, M., KUNZENDORF, U., QIN, Z., DIAMANTSTEIN, T., and BLANKENSTEIN, T. (1993). Mechanisms of rejection induced by tumor cell targeted gene transfer of IL-2, IL-4, IL-7, TNF and IFN-τ. Proc. Natl. Acad. Sci. USA 90, 2774-2778.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2774-2778
    • Hock, H.1    Dorsch, M.2    Kunzendorf, U.3    Qin, Z.4    Diamantstein, T.5    Blankenstein, T.6
  • 35
    • 0025755537 scopus 로고
    • Reduced tumorigenicity of murine tumor cells secreting IFN-τ is due to nonspecific host responses and is unrelated to class I major histocompatibility complex expression
    • ESUMI, N., HUNT, B., ITAYA, T., and FROST, P. (1991). Reduced tumorigenicity of murine tumor cells secreting IFN-τ is due to nonspecific host responses and is unrelated to class I major histocompatibility complex expression. Cancer Res. 51, 1185-1189.
    • (1991) Cancer Res. , vol.51 , pp. 1185-1189
    • Esumi, N.1    Hunt, B.2    Itaya, T.3    Frost, P.4
  • 36
    • 0027298471 scopus 로고
    • Antimetastatic vaccination of tumor-bearing mice with two types of IFN-τ gene-inserted tumor cells
    • PORGADOR, A., BENNERJI, R., WATANABE, Y., FELDMAN, M., GILBOA, E., and EISENBACH, L. (1993). Antimetastatic vaccination of tumor-bearing mice with two types of IFN-τ gene-inserted tumor cells. J. Immunol. 150, 1458-1470.
    • (1993) J. Immunol. , vol.150 , pp. 1458-1470
    • Porgador, A.1    Bennerji, R.2    Watanabe, Y.3    Feldman, M.4    Gilboa, E.5    Eisenbach, L.6
  • 37
    • 0022598381 scopus 로고
    • High levels of Met-72 antigen expression: Correlation with metastatic activity of B16 melanoma tumor cell variants
    • KIMURA, A., and XIANG, J. (1986). High levels of Met-72 antigen expression: correlation with metastatic activity of B16 melanoma tumor cell variants. J. Natl. Cancer Inst. 76, 1247-1253.
    • (1986) J. Natl. Cancer Inst. , vol.76 , pp. 1247-1253
    • Kimura, A.1    Xiang, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.