Role of the gut in the pathophysiology of extrahepatic biliary obstruction

Gut

Volumn 39, Issue 4, 1996, Pages 587-593

  Clements, W D B ^a,b   Parks, R ^a   Erwin, P ^a   Halliday, M I ^a   Barr, J ^a   Rowlands, B J ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b Department of Surgery   (United Kingdom)

Author keywords

Bacterial translocation; Bile salts; Jaundice; Sepsis

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL FLORA; ENDOTOXEMIA; EXTRAHEPATIC BILE DUCT OBSTRUCTION; GRAM NEGATIVE BACTERIUM; JAUNDICE; MORBIDITY; MORTALITY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SEPSIS;

EID: 0029909320     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.39.4.587     Document Type: Article

References (25)

1. Holman JM, Rikkers LF, Moody FG. Sepsis in management of complicated biliary disorders. Am J Surg 1979; 138: 809-13.
2. Armstrong CP, Dixon JM, Taylor TV, Davies GC. Surgical experience of deeply jaundiced patients with bile duct obstruction. Br J Surg 1984; 71: 234-8.
3. Lai EC, Chu KM, Lo CY, et al. Surgery for malignant obstructive jaundice: analysis of mortality. Surgery 1992; 112:891-6.
4. Diamond T, Rowlands BJ. Endotoxaemia in obstructive jaundice. HPB Surg 1991; 4: 81-4.
5. Bailey ME. Endotoxin, bile salts and renal function in obstructive jaundice. Br J Surg 1976; 66: 392-7.
6. Drivas G, James O, Wardle N. Study of the reticuloendothelial phagocytic capacity in patients with cholestasis. BM J 1976; 1: 1568-9.
7. Dunn CW, Horton JW. Impairment of mononuclear phagocyte system function in obstructive jaundice. FASEB J 1989;3:A930.
8. Clements WDB, Halliday MI, McCaigue MD, Barclay GR, Rowlands BJ. The effects of extrahepatic obstructive jaundice on Kupffer cell clearance capacity (KCCC). Arch Surg 1993; 128: 200-5.
9. Deitch EA, Sittig K, Li M, Berg R, Specian RD. Obstructive jaundice promotes bacterial translocation from the gut. Am J Surg 1990; 159: 79-84.
10. Ding JW, Andersson R, Soltesz V, Willen R, Bengmark S. Obstructive jaundice impairs reticuloendothelial function and promotes bacterial translocation in the rat. J Surg Res 1994; 57: 238-15.
11. Lee E. The effect of obstructive jaundice on the migration of reticuloendothelial cells and fibroblasts into early experimental granulomata. Br J Surg 1972; 59: 875-7.
12. Diamond T, Rowlands BJ. Choledochovesical fistula: a model for sterile 'external' biliary drainage. Surg Res Conun 1990; 8: 131-8.
13. Scott BB, Barclay RG. Endotoxin-polymyxin complexes in an improved enzyme-linked immunosorbent assay for IgG antibodies in blood donor sera to gram-negative endotoxin core glycolipids. Vox Sang 1987; 52: 272-80.
14. Sikora SS, Kapoor R, Pradeep R, Kapoor VK, Saxena R, Kaushik SP. Palliative surgical treatment of malignant obstructive jaundice. Eur J Surg Oncol 1994; 20: 580-4.
15. Bakkevold KE, Kambestad B. Morbidity and mortality after radical and palliative pancreatic cancer surgery. Risk factors influencing the short-term results. Ann Surg 1993; 217:356-68.
16. Su CH, P'eng FK, Lui WY. Factors affecting morbidity and mortality in biliary tract surgery. World J Surg 1992; 16: 536-40.
17. Wait RB, Kahng KU. Renal failure complicating obstructive jaundice. Am J Surg 1989; 157: 256-63.
18. Hunt DR, Allison MEM, Prentice CRM, Blumgart LH. Endotoxaemia, disturbance of coagulation, and obstructive jaundice. Am J Surg 1982; 144: 325-9.
19. Grande L, Garcia-Valdecasas JC, Fuster J, Visa J, Pera C. Obstructive jaundice and wound healing. Br J Surg 1990; 77: 440-2.
20. Wilkinson SP, Moodie H, Stamatakis JD, Kakkar W, Williams R. Endotoxaemia and renal failure in cirrhosis and obstructive jaundice. BM J 1976; 2: 1415-8.
21. Wardle EN, Wright NA. Endotoxin and acute renal failure associated with obstructive jaundice. BM J 1970; 4: 472-1.
22. Greve JW, Gouma DJ, Soeters PB, Buurman WA. Suppression of cellular immunity in obstructive jaundice is caused by endotoxins: a study with germ free rats. Gastroenterology 1990; 98: 478-85.
23. Diamond T, Rowlands BJ. Endotoxaemia in obstructive jaundice: the role of gastrointestinal bile flow. Surg Res Comm 1989; 5: 11-6.
24. Clements B, Halliday I, Erwin P, McCaigue M, Barclay GR, Rowlands BJ. Conclusive evidence for endotoxaemia in biliary obstruction. Gut 1993; 34 (suppl 4): F223.
25. Bemelemans MHA, Greve JW, Gouma DT, Buurmann WA. Cytokines, tumour necrosis factor and interleukin-6 in experimental biliary obstruction in mice. Hepatology 1992; 15: 1132-6.