Epidermal growth factor induces glucose storage in transgenic 3T3-L1 adipocytes overexpressing epidermal growth factor receptors

Diabetes

Volumn 45, Issue 11, 1996, Pages 1619-1625

  Van Epps Fung, Mark ^a,b   Hardy, Robert W ^a   Williford, Jodle ^a   Gupta, Kiran ^a,b   Wells, Alan ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b BIRMINGHAM VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYCLOHEXIMIDE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GLYCOGEN; GLYCOGEN SYNTHASE; INSULIN;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN 3T3; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION; GLUCOSE TRANSPORT; GLYCOGEN SYNTHESIS; HORMONAL REGULATION; MOUSE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

EID: 0029909116     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.45.11.1619     Document Type: Article

References (43)

1. Taylor SI, Accili D, Imai Y: Insulin resistance or insulin deficiency: which is the primary cause of NIDDM? Diabetes 43:735-739, 1994
2. Turner RC, Hattersley AT, Shaw JTE, Levy JC: Type II diabetes: clinical aspects of molecular biological studies. Diabetes 44:1-10, 1995
3. DeFronzo RA, Bonadonna RC, Ferrannini E: Pathogenesis of NIDDM: a balanced overview. Diabetes Care 15:318-368, 1992
4. Myers MG Jr, Backer JM, Sun XJ, Shoelson S, Hu P, Schlessinger J, Yaokim M, Schaffhausen B, White MF: IRS-1 activates phosphatidylinositol 3′-kinase by associating with src homology 2 domains of p85. Proc Natl Acad Sci USA 89:10350-10354, 1992
5. White MF, Kahn CR: The insulin signaling system. J Biol Chem 269:1-4, 1994
6. Ruderman NB, Kapeller R, White MF, Cantley LC: Activation of phosphatidylinositol 3-kinase by insulin. Proc Natl Acad Sci USA 87:1411-1415, 1990
7. Lavoinne A, Erikson E, Maller JL, Price DJ, Avruch J, Cohen P: Purification and characterisation of the insulin-stimulated protein kinase from rabbit skeletal muscle; close similarity to S6 kinase II. Eur J Biochem 199:723-728, 1991
8. Dent P, Lavoinne A, Nakielny S, Caudwell F, Watt P, Cohen P: The molec- ular mechanisms by which insulin stimulates glycogen synthesis in mammalian skeletal muscle. Nature 348:302-308, 1990
9. Standaert ML, Bandyopadhyay G, Farese RV: Studies with wortmannin suggest a role for phosphatidylinositol 3-kinase in the activation of glycogen synthase and mitogen-activated protein kinase by insulin in rat adipocytes: comparison of insulin and protein kinase C modulators Biochem Biophys Res Com 209:1082-1088, 1995
10. Okada T, Kawano Y, Sakakibara T, Hazeki O, Ui M: Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. J Biol Chem 269:3508-3573, 1994
11. Sakaue H, Hara K, Noguchi T, Matozaki T, Kotani K, Ogawa W: Ras-independent and wortmannin-sensitive activation of glycogen synthase by insulin in Chinese hamster ovary cells. J Biol Chem 270:11304-11309, 1995
12. Lazar DF, Wiese RJ, Brady MJ, Mastick CC, Waters SB, Yamauchi K, Pessin JE, Cuatrecasas P, Saltiel AR: Mitogen-activated protein kinase inhibition does not block the stimulation of glucose utilization by insulin. J Biol Chem 270:20801-20807, 1995
13. Wiese RJ, Mastick CC, Lazar DF, Saltiel AR: Activation of mitogen-activated protein kinase and phosphatidylinositol 3′-kinase is not sufficient for the hormonal stimulation of glucose uptake, lipogenesis, or glycogen synthesis in 3T3-L1 adipocytes. J Biol Chem 270:3442-3446, 1995
14. Lin T-A, John C, Lawrence J: Activation of ribosomal protein s6 kinases does not increase glycogen synthesis or glucose transport in rat adipocytes. J Biol Chem 269:21255-21261, 1994
15. Tanemoto H, Kadowaki T, Tobe K, Yagi T, Sakura H, Hayakawa T, Terauchi Y, Ueki K, Kaburagi Y, Satoh S, Sekihara H, Yoshioka S, Horikoshi H, Furuta Y, Ikawa Y, Kasuga M, Yazaki Y, Aizawa S: Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1, Nature 372:182-186, 1994
16. Araki E, Lipes MA, Patti M-E, Bruning JC, Haag B, Johnson RS, Kahn CR: Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene. Nature 372:186-190, 1994
17. Hardy RW, Gupta KB, McDonald JM, Williford J, Wells A: Epidermal growth factor (EGF) receptor carboxy-terminal domains are required for EGF-induced glucose transport in transgenic 3T3-L1 adipocytes. Endocrinol 136:431-439, 1995
18. O'Keefe E, Hollenberg MD, Cuatrecasas P: Epidermal growth factor: characteristics of specific binding in membranes from liver, placenta, and other target tissues. Arch Biochem Biophys 164:518-526, 1974
19. Stagsted J, Ziebe S, Satoh S, Holman GD, Cushman SW, Olsson L: Insulinomimetic effect on glucose transport by epidermal growth factor when combined with a major histocompatibility complex class-I derived peptide. J Biol Chem 268:1770-1774, 1993
20. Robinson LJ, Razzack ZF, John C, Lawrence J, James DE: Mitogen-activated protein kinase activation is not sufficient for stimulation of glucose transport or glycogen synthase in 3T3-L1 adipocytes. J Biol Chem 268:26422-26437, 1993
21. Fingar DC, Hausdorff SF, Blenis J, Birnbaum MJ: Dissociation of pp70 ribosomal s6 kinase from insulin-stimulated glucose transport in 3T3-L1 adipocytes. J Biol Chem 268:3005-3008, 1993
22. Reed BC, Lane MD: Insulin receptor synthesis and turnover in differentiating 3T3-L1 preadipocytes. Proc Natl Acad Sci USA 77:285-289, 1980
23. Wells A, Welsh JB, Lazar CS, Wiley HS, Gill GN, Rosenfeld MG: Ligand-induced transformation by a non-internalizing EGF receptor. Science 247:962-964, 1990
24. Lawrence JC Jr, Larner J: Activation of glycogen synthase in rat adipocytes by insulin and glucose involves increased glucose transport and phosphorylation. J Biol Chem 253:2104-2113, 1978
25. 14C-glucose. Analytical Biochem 25:486-499, 1968
26. Bligh EG, Dyer WJ: A rapid method of total lipid extraction and purification. Canad J Biochem Physiol 37:911-917, 1959
27. Trinder P: Determination of blood glucose using an oxidase-peroxidase system with a non-carcinogenic chromogen. J Clin Pathol 22:158-161, 1969
28. Chan CP, Krebs EG: Epidermal growth factor stimulates glycogen synthase activity in cultured cells. Proc Natl Acad Sci USA 82:4563-4567, 1985
29. Hjøllund E, Pedersen O: Transport and metabolism of D-glucose in human adipocytes: studies of the dependence on medium glucose and insulin concentrations. Biochim Biophys Acta 937:93-102, 1988
30. Soler C, Alvarez CV, Beguinot L, Carpenter G: Potent SHC tyrosine phosphorylation by epidermal growth factor at low receptor density or in the absence of autophosphorylation sites. Oncogene 9:2207-2215, 1994
31. Cook SJ, McCormick F: Inhibition by cAMP of ras-dependent activation of raf. Science 262:1069-1072, 1893
32. vanBiesen T, Hawes BE, Luttrell DK, Krueger KM, Touhara K, Porfiri E, Sakaue M, Luttrell LM, Lefkowitz RJ: Receptor-tyrosine-kinase- and Gbg-mediated MAP kinase activation by a common signalling pathway. Nature 376:781-784, 1995
33. Okada S, Yamauchi K, Pessin JE: Shc isoform-specific tyrosine phosphorylation by the insulin and epidermal growth factor receptors. J Biol Chem 270:20737-20741, 1995
34. Pronk GJ, McGlade J, Pelicci G, Pawson T, Bos JL: Insulin-induced phosphorylation of the 46- and 52-kDa shc proteins. J Biol Chem 268:5748-5753, 1993
35. Klarlund JK, Cherniack AD, Czech MP: Divergent mechanisms for homologous desensitization of p21ras by insulin and growth factors. J Biol Chem 270:23421-23428, 1995
36. Hu P, Margolis B, Skolnik EY, Lammers R, Ullrich A, Schlessinger J: Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors. Mol Cell Biol 12:981-990, 1992
37. Yamauchi K, Pessin JE: Insulin receptor substrate-1 (IRS1) and Shc compete for a limited pool of Grb2 in mediating insulin downstream signaling. J Biol Chem 269:31107-31114, 1994
38. mapkinase by insulin does not correlate with its metabolic actions in cells overexpressing mutant insulin receptors. Biochem Biophys Res Com 196:301-310, 1993
39. Osterop APRM, Medema RH, Bos JL, Zon GCMvd, Moller DE, Flier JS, Moller W, Maassen JA: Relation between the insulin receptor number in cells, autophosphorylation and insulin-stimulated Ras GTP formation. J Biol Chem 267:14647-14653, 1992
40. Moller DE, Benecke H, Flier JS: Biologic activities of naturally occurring human insulin receptor mutations. J Biol Chem 266:10995-11001, 1991
41. Katz EB, Stenbit AE, Hatton K, DePinho R, Charron MJ: Cardiac and adipose tissue abnormalities but not diabetes in mice deficient for GLUT4. Nature 377:151-155, 1995
42. Maddux BA, Sbraccia P, Kumakura S, Sasson S, Youngren J, Fisher A, Spencer S, Grupe A, Henzel W, Stewart TA, Reaven GM, Goldfine ID: Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus. Nature 373:448-451, 1995
43. Reynet C, Kahn CR: Rad: a member of the Ras family overexpressed in muscle of type II diabetic humans. Science 262:1441-1444, 1993