An Inhibition of Urinary Albumin Excretion by Protease Inhibitor in Streptozotocin-Diabetic Rats

Nephron

Volumn 74, Issue 4, 1996, Pages 709-712

  Ikeda, Tadasu ^a   Hoshino, Tazue ^a  

^a TOTTORI UNIVERSITY   (Japan)

Author keywords

Albuminuria; Diabetes mellitus; Protease inhibitor

Indexed keywords

ALBUMIN; CAMOSTAT MESILATE; PROTEINASE INHIBITOR; SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIABETIC NEPHROPATHY; KIDNEY HYPERTROPHY; KIDNEY MASS; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTEINURIA; RAT; STREPTOZOCIN DIABETES;

EID: 0029907740     PISSN: 16608151     EISSN: 22353186     Source Type: Journal    
DOI: 10.1159/000189479     Document Type: Article

References (19)

1. Cohen D. Dodds R, Viberti G: Effect of protein restriction in insulin-dependent diabetics at risk of nephropathy. Br Med J 1987:294:795-798.
2. Zatz R. Meyer TW. Rennkc HG. Brenner BM: Predominance of hemodynamic rather than metabolic factors in the pathogenesis of diabetic glomerulopathy. Proe Natl Acad Sci USA 1985:82:5963-5967.
3. Mauer SM. StelTes MW. Azar S, Brown DM: Effects of dietary protein content in streptozo-tocin-diabetic rats. Kidney Ini 1989:35:48-59.
4. 1-esterase. Biochim Biophys Acta 1977:484:417-422.
5. Takahashi H. Fukase N. Tominaga M. Sasaki H, Matsuhashi A. Ito M. Taguma Y, Matsuba-ra M: Three cases of diabetic nephropathy successfully treated with camostat mesylate. J Jpn Diabetic Soc 1990:33:973-978.
6. D'Ercotc AJ. Stiles AD. Underwood LE: Tissue concentration of somatomedin C: Further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action. Proe Natl Acad Sci USA 1984;81:935-939.
7. Ikeda T, Takeuchi T, Honda M, Mokuda O. Tominaga M, Mashiba H: Somatomedin-C in the kidney of streptozotocin diabetic rats. Bio-ehem Med Mctab Biol 1988:40:276-281.
8. Mogensen CE. Andersen MJ: Increased kidney size and glomerular filtration rate in early juvenile diabetes. Diabetes 1973:22:706-712.
9. Ross J, Goldman JK: Effect of streptozotocin-induccd diabetes on kidney weight and compensatory hypertrophy in the rat. Endocrinology 1971:88:1079-1082.
10. Christiansen JS. Gammelgaard J. Frandscn M. Pars ing H-H: Increased kidney size, glomerular filtration rate and renal plasma flow in short-term insulin-dependent diabetics. Diabe-tologia 1981:20:451-456.
11. Puig JG, Anton FM. Grande C. Paliardo LF, Arnalich F. Gil A. Vâzquez JJ. Garcia AM: Relation of kidney size to kidney function in early juvenile diabetes. Diabetologia 1981:20: 363-367.
12. Seyer-Hansen K: Renal hypertrophy in strepto-zotoein-diabetie rats. Clin Sci Mol Med 1976: 51:551-555.
13. Brenner BM. I lostetter TH. Olsen JL, Rennke HG. Venkatachalam MA: The role of glomerular hyperfiltration in the initiation and progression of diabetic nephropathy. Acta Endocrinol 1981:97(suppl 242):7-10.
14. Mogensen CE: Early glomerular hypernitration in insulin-dependent diabetics and late nephropathy. Stand.J Clin Lab Invest 1986:46: 201-206
15. Seyer-Hansen K: Renal hypertrophy in strcplo-zotocin-diabetic rats. Clin Sci Mol Med 1976; 51:551-555.
16. Ihse I. Lundquist I. Amesjo B: Oral trypsin inhibitor-induced improvement of the exocrine and endocrine pancreatic functions in alloxan-diabetic rats. Scand J Gastroenterol 1976:11:363-368.
17. Lundquist I. Ihse I. Amesjo B: Carbohydrate metabolism in normal and diabetic rats following long-term oral trypsin inhibitor administration. Scand J Gastroenterol 1976:11:369-375.
18. Flyvbjerg A, Thorlacius-Ussing O, Nairaa R. Ingerslev J, Orskov H: Kidney tissue somatomedin C and initial renal growth in diabetic and unincphrcctomized rats. Diabetologia 1988;31:310-314.
19. Flyvbjerg A. Bronfeldt KE. Marshal SM, Arn-qvist HJ. Ørskov H: Kidney IGH-I mRNA in initial renal hypertrophy in experimental diabetes in rats. Diabetologia 1990:33:334-338.