Racial variation of cord plasma lipoprotein(a) levels in relation to coronary risk level: A study in three ethnic groups in Singapore

Pediatric Research

Volumn 40, Issue 5, 1996, Pages 718-722

  Low, P S ^a   Heng, C K ^a   Saha, N ^a,b   Tay, J S H ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPROTEIN A;

ADULT; ARTICLE; ATHEROSCLEROSIS; BIRTH WEIGHT; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY RISK; ETHNIC GROUP; FEMALE; GESTATIONAL AGE; HUMAN; INFANT; INHERITANCE; LIPOPROTEIN BLOOD LEVEL; MALE; NEWBORN; PREVALENCE; PRIORITY JOURNAL; RACE DIFFERENCE; SINGAPORE; UMBILICAL CORD BLOOD;

EID: 0029907569     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-199611000-00011     Document Type: Article

References (17)

1. Rhoads GG. Dahlen G, Berg K, Morton NE, Dannenberg AL 1986 Lp(a) lipoprotein as a risk factor for myocardial infarction. JAMA 256:2540-2544
2. Utermann G, Hoppichler F, Dieplinger H, Seed M, Thompson G, Boerwinkle E 1989 Defects in the low density lipoprotein receptor gene affect lipoprotein(a) levels: multiplicative interaction of two gene loci associated with premature atherosclerosis. Proc Natl Acad Sci USA 86:4171-4174
3. Rosengren A, Wilhelmsen L, Eriksson E, Risberg B, Wedel H 1990 Lipoprotein(a) and coronary heart disease: a prospective case-control study in a general population sample of middle aged men. BMJ 301:1248-1251
4. Scanu AM, Fless GM 1990 Lipoprotein(a): heterogeneity and biological relevance. J Clin Invest 85:1709-1915
5. Seed M, Hoppichler F, Reaveley D, McCarthy S, Thompson GR, Boerwinkle E, Utermann G 1990 Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial hypercholesterolemia. N Engl J Med 322:1494-1499
6. Lackner C, Boerwinkle E, Leffert CC, Rahmig T, Hobbs HH 1991 Molecular basis of apolipoprotein(a) isoform size heterogeneity as revealed by pulsed-field gel electrophoresis. J Clin Invest 87:2077-2086
7. Boerwinkle E, Leffert CC, Lin J, Lackner C, Chiesa G, Hobbs HH 1992 Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations. J Clin Invest 90:52-60
8. Sandholzer CH, Boerwinkle E, Saha N, Tong MC, Utermann G 1992 Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population: evidence for the role of the apo(a) gene in coronary heart disease. J Clin Invest 89:1040-1046
9. Sandholzer CH, Hallman DM, Saha N, Sigurdsson G, Lackner C, Csaszar A, Boerwinkle E, Utermann G 1991 Effects of the apolipoprotein(a) size polymorphism on the lipoprotein(a) concentration in 7 ethnic groups. Hum Genet 86:607-614
10. Danaraj TJ, Acker KS. Danaraj W, Ong WH, Tan BY 1959 Ethnic group differences in coronary heart disease in Singapore: an analysis of necropsy records. Am Heart J 58:516-526
11. Hughes K, Lun KC, Yeo PPB 1990 Cardiovascular diseases in Chinese, Malays and Indians in Singapore. I. Differences in mortality. J Epidemiol Community Health 44:24-28
12. Sandholzer C, Saha N, Kark JD, Rees A, Jaross W, Dieplinger H, Hoppichler F, Boerwinkle E, Utermann G 1992 Apo(a) isoforms predict risk of coronary heart disease. Arterioscler Thromb 12:1214-1226
13. Van Biervliet JP, Labeur C, Michiels G, Usher DC, Rosseneu M 1991 Lipoprotein(a) profiles and evolution in newborns. Atherosclerosis 86:173-181
14. Wang XL, Wilcken DEL, Dudman NPB 1992 Expression of the apolipoprotein(a) gene: relationships between infants' and their parents' serum apolipoprotein(a) levels. Pediatrics 89:401-406
15. Strobl W, Widhalm K, Kostner G, Pollak A 1983 Serum apolipoproteins and lipoprotein(a) during the first week of life. Acta Pediatr Scand 72:505-509
16. Wang XL, Wilcken DEL, Dudman NPB 1990 Neonatal apo A-I, apo B, and apo(a) levels in dried blood spots in an Australian population. Pediatr Res 28:496-501
17. Heng CK, Saha N, Tay JSH 1995 Lack of association of apolipoprotein E polymorphism with plasma Lp(a) levels in the Chinese. Clin Genet 48:113-119