2,4-cis- and trans-venezinones: New bioactive ketolactone Annonaceous acetogenins, lacking tetrahydrofuran rings, from Xylopia aromatica

Phytochemical Analysis

Volumn 7, Issue 6, 1996, Pages 313-317

  Colman Saizarbitoria, Trina ^a   Alfonso, Dorothée ^b   McLaughlin, Jerry L ^b  

^a UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Acetogenin; Annonaceae; Bioactivity directed fractionation; Ketolactone acetogenin; Non tetrahydrofuran ring acetogenin; Xylopia

Indexed keywords

CELL CULTURE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ACETOGENINS; ANNONACEAE; BIOACTIVITY-DIRECTED FRACTIONATION; KETOLACTONE; KETOLACTONE ACETOGENIN; NON-TETRAHYDROFURAN RING ACETOGENIN; TETRA-HYDROFURAN; TETRAHYDROFURANS; XYLOPIUM;

MASS SPECTROMETRY;

ACETOGENIN; LACTONE DERIVATIVE; TETRAHYDROFURAN DERIVATIVE;

ARTEMIA; ARTICLE; CYTOTOXICITY; FAST ATOM BOMBARDMENT MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ANNONACEAE; ANOSTRACA; ARTEMIA; DECAPODA (CRUSTACEA); XYLOPIA; XYLOPIA AROMATICA;

EID: 0029907258     PISSN: 09580344     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1565(199611)7:6<313::AID-PCA316>3.0.CO;2-Z     Document Type: Article

References (9)

1. Ahammadsahib, K. I., Hollingworth, R.M., McGovren, J. P., Hui Y.-H. and McLaughlin, J. L. (1993). Mode of action of bullatacin: a potent antitumor and pesticidal Annonaceous acetogenin. Life Sci. 53, 1113-1120.
2. Cavé, A., Cortes, D., Figadere, B., Hocquemiller, R., Laprevote, O., Laurens, A. and Leboeuf, A. M. (1993). Recent advances with the acetogenins of Annonaceae. In Recent Advances in Phytochemistry (Downum, K.R., Romeo, J. T. and Stafford, H. A., eds.), vol. 27, pp. 167-202. Plenun Press, New York.
3. Colman-Saizarbitoria, T. Zambrano, J., Ferrigni, N., Gu, Z.-M., Ng, J. H., Smith, D.L. and McLaughlin, J. L. (1994a). Bioactive Annonaceous acetogenins from the bark of Xylopia aromatica. J. Nat. Prod. 57, 486-493.
4. Colman-Saizarbitoria, T., Gu, Z.-M. and McLaughlin, J. L. (1994b). Two new bioactive Annonaceous acetogenins from the bark of Xylopia aromatica. J. Nat. Prod. 57, 1661-1669.
5. Colman-Saizarbitoria, Gu, Z.-M. and McLaughlin, J.L (1995). Venezenin: a new bioactive Annonaceous acetogenin from the bark of Xylopia aromatica. J. Nat. Prod. 58, 532-539.
6. Duret, P., Laurens, A., Hocquemiller, R., Cortes, D. and Cavé, A. (1994). Isoacetogenins, artifacts issued from translactonization from Annonaceous acetogenins. Heterocycles 39, 741-749.
7. Fang, X.P., Rieser, M., Gu, Z.-M., Zhao, G.-X. and McLaughlin, J. L. (1993a). Annonaceous acetogenins: an updated review. Phytochem. Anal. 4, 27-109.
8. Fang, X.-P., Song, R., Gu, Z.-M., Rieser, M. J., Miesbauer, L. R., Smith, D. L. and McLaughlin, J. L. (1993b). A new type of cytotoxic Annonaceous acetogenin: giganin from Goniothalamus giganteus. Bioorg. Med. Chem. Lett. 3, 1153-1156.
9. Fogh, J. and Trempe, G. (1975). New human tumor cell lines. In Human Tumor Cells In Vitro (Fogh, J., ed.), pp. 115-159. Plenum Press, New York.