Functional analysis of trk proto-oncogene product in medulloblastoma cells

Neurologia Medico-Chirurgica

Volumn 36, Issue 11, 1996, Pages 796-804

  Kokunai, Takashi ^a   Sawa, Hideki ^a   Tamaki, Norihiko ^a  

^a KOBE UNIVERSITY   (Japan)

Author keywords

apoptosis; differentiation; medulloblastoma; nerve growth factor; nerve growth factor receptor; proto oncogene

Indexed keywords

NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; TROPOMYOSIN;

APOPTOSIS; ARTICLE; GENE EXPRESSION REGULATION; GROWTH REGULATION; HUMAN; HUMAN CELL; MEDULLOBLASTOMA; NERVE CELL DIFFERENTIATION; NERVE GROWTH; PROTEIN PROTEIN INTERACTION; PROTO ONCOGENE;

EID: 0029906036     PISSN: 03872572     EISSN: None     Source Type: Journal    
DOI: 10.2176/nmc.36.796     Document Type: Article

References (57)

1. Baker DL, Reddy UR, Pleasure S, Hardy M, Williams M, Tartagline M, Biegel JA, Emanuel BS, Presti PL, Kreider B, Trojanowski JQ, Evans A, Ray AR, Venkatakrishnan G, Chen J, Ross AH, Pleasure D: Human central nervous system primitive neuroectodermal tumor expressing nerve growth factor receptors: CHP 707m. Ann Neurol 28: 136-145, 1990
2. LNTR reduces NGF binding to trk A on PC 12 cells. Neuron 13: 201-215, 1994
3. Banerjee SP, Synder SH, Cuatrecasas P, Greene LA: Binding of nerve growth factor in superior cervical ganglia. Proc Natl Acad Sci U S A 70: 2519-2523, 1973
4. Barbacid M: Nerve growth factor: A tale of two receptors. Oncogene 8: 2033-2042, 1993
5. LNGFR on MAH cells. Science 257: 395-397, 1992
6. Chen J, Chattopadhyay B, Venkatakrishnan G, Ross AH: Nerve growth factor-induced differentiation of human neuroblastoma and neuroepithelioma cell line. Cell Growth Differ 1: 79-85, 1990
7. Chesa PG, Rettig WJ, Thomson TM, Old LJ, Melanmed MR: Immunohistochemical analysis of nerve growth factor receptor expression in normal and malignant human tissues. J Histochem Cytochem 36: 383-389, 1988
8. Dickson G, Prentice H, Julien J-P, Ferrari G, Leon A, Walsh FS: Nerve growth factor activates Thy-1 and neurofilament gene transcription in rat PC 12 cells. EMBO J 5: 3449-3453, 1986
9. Edelman AM, Blumenthal DK, Krebs EG: Protein serine/threonine kinases. Annu Rev Biochem 56: 577-613, 1987
10. Greenberg ME, Ziff EB: Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature 311: 433-438, 1984
11. Greene LA, Rein G: Synthesis, storage and release of acetylcholine by a noradrenergic pheochromocytoma cell line. Nature 268: 349-351, 1977
12. Greene LA, Tischler AS: Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci U S A 73: 2424-2428, 1976
13. Halegoua S, Armstrong RC, Kremer NE: Dissecting the mode of action of a neuronal growth factor. Curr Top Microbiol Immunol 165: 119-170, 1991
14. Hantzopoulos PA, Suri C, Glass DJ, Goldfarb MP, Yancopoulos GD: The low affinity NGF receptor, p75, can collaborate with each of the trks to potentiate functional responses to the neurotrophins. Neuron 13: 187-201, 1994
15. Hempstead BL, Martin-Zanca D, Kaplan DR, Parada L, Chao M: High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor. Nature 350: 678-683, 1991
16. Hempstead BL, Schleifer LS, Chao M: Expression of functional nerve growth factor receptors after gene transfer. Science 243: 373-375, 1989
17. Herrup K, Schooler EM: Properties of the β-nerve growth factor receptor of avian dorsal root ganglia. Proc Natl Acad Sci U S A 70: 3884-3888, 1973
18. Hosang M, Shooter EM: Molecular characteristics of nerve growth factor receptors on PC 12 cells. J Biol Chem 260: 655-662, 1985
19. Hsu SM, Paine L, Fanger H: Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: Comparison between ABC and unlabelled procedure (PAP). J Histochem Cytochem 29: 577-580, 1981
20. Johnson D, Lanahan A, Buck CR, Sehgel A, Morgan C, Mercer E, Bothwell NW, Chao M: Expression and structure of the human NGF receptor. Cell 47: 545-554, 1986
21. Johnson EM Jr, Gorin PD, Brandeis ID, Pearson D: Dorsal root ganglion neurons are destroyed by exposure in utero to maternal antibody to nerve growth factor. Science 210: 916-918, 1980
22. Kaplan DR, Hempstead BL, Martin-Zanca D, Chao M, Parada L: The trk proto-oncogene product: A signal transducing receptor for nerve growth factor. Science 252: 554-558, 1991
23. Kaplan DR, Martin-Zanca D, Parada L: Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF. Nature 340: 158-160, 1991
24. Klein R, Jing S, Nanduri V, O'Rouke E, Barbacid M: The trk proto-oncogene encodes a receptor for nerve growth factor. Cell 65: 189-197, 1991
25. Kokunai T, Korosue T, Tamaki N, Matsumoto S: Promoting effect of 12-O-tetradecanoylphorbol-13-acetate on the in vitro malignant transformation of fetal rat brain cells exposed in utero to ethylnitrosourea. Cancer Res 46: 1377-1381, 1986
26. Kokunai T, Sawa H, Tatsumi S, Tamaki N: Expression of nerve growth factor receptor by human primitive neuroectodermal tumors. Neurol Med Chir (Tokyo) 34: 523-529, 1994
27. Kokunai T, Tamaki N, Matsumoto S: ACNU-resistant mutants of 9L rat glioma cell line. Isolation and preliminary characterization of these subclones. J Neurosurg 63: 583-588, 1985
28. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970
29. Lee K-F, Li E, Huber LJ, Landis SC, Sharpe AH, Chao MV, Jaenisch R: Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell 69: 737-749, 1992
30. Leonard DGB, Ziff EB, Greene LE: Identification and characterization of mRNAs regulated by nerve growth factor in PC 12 cells. Mol Cell Biol 7: 3156-3167, 1987
31. Lindenbaum MH, Carbonetto S, Grosveld F, Flavell D, Mushynski WE: Transcriptional and post-transcriptional effects of nerve growth factor on expression of the three neurofilament subunits in PC-12 cells. J Biol Chem 263: 5662-5667, 1988
32. Lindenbaum MH, Carbonetto S, Mushynski WE: Nerve growth factor enhances the synthesis, phosphorylation, and metabolic stability of neurofilament proteins in PC 12 cells. J Biol Chem 262: 605-610, 1987
33. Maher PA: Nerve growth factor induces protein-tyrosine phosphorylation. Proc Natl Acad Sci U S A 85: 6788-6791, 1988
34. Martin-Zanca D, Oskam R, Mitra G, Copeland T, Barbacid M: Molecular and biochemical characterization of the human trk proto-oncogene. Mol Cell Biol 9: 24-33, 1989
35. Matsushima H, Bogenmann E: Nerve growth factor (NGF) induces neuronal differentiation in neuroblastoma cells transfected with the NGF receptor cDNA. Mol Cell Biol 10: 5015-5020, 1990
36. Matsushima H, Bogenmann E: Expression of trk A cDNA in neuroblastomas modulates differentiation in vitro and in vivo. Mol Cell Biol 13: 7447-7456, 1993
37. Miyada CG, Wallace RB: Oligonucleotide hybridization techniques. Methods Enzymol 154: 94-107, 1987
38. Nakagawa A, Arima M, Azar CG, Scavarda NJ, Brodeur GM: Inverse relationship between trk expression and N-myc amplification in human neuroblastoma. Cancer Res 52: 1364-1368, 1988
39. Perosio PM, Brooks JJ: Expression of nerve growth factor receptor in paraffin-embedded soft tissue tumors. Am J Pathol 132: 152-160, 1988
40. Pleasure SJ, Reddy UR, Venkatakrishnan G, Roy AK, Chen J, Ross AH, Trojanowski JQ, Pleasure DE, Lee VM-Y: Introduction of nerve growth factor (NGF) receptors into a medulloblastoma cell line results in expression of high- and low-affinity NGF receptors but not NGF-mediated differentiation. Proc Natl Acad Sci U S A 87: 8496-8500, 1990
41. Radeke MJ, Misko TP, Hsu C, Herzenberg LA, Shooter EM: Gene transfer and molecular cloning of the rat nerve growth factor receptor. Nature 325: 593-597, 1987
42. Ross AH, Sobue G, Hotta H, Reddy UR: Biochemical characterization of the nerve growth factor receptor in neural-related tumors. Curr Top Microbiol Immunol 165: 27-38, 1991
43. Rovelli G, Heller RA, Canossa M, Shooter EM: Chimeric tumor necrosis factor-Trk A receptors reveal that ligand-dependent activation of the Trk A tyrosine kinase is sufficient for differentiation and survival of PC 12 cells. Proc Natl Acad Sci U S A 90: 8717-8721, 1993
44. Schatteman GC, Gibbs L, Lenahann AA, Claude P, Bothwell H: Expression of NGF receptor in the developing and adult primate central nervous system. J Neurosci 8: 860-873, 1988
45. Schechter AL, Bothwell MA: Nerve growth factor receptors on PC 12 cells: Evidence for two receptor classes with differing cytoskeletal association. Cell 24: 867-874, 1981
46. Seed B, Aruffo A: Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor by a rapid immunoselection procedure. Proc Natl Acad Sci U S A 84: 3365-3369, 1987
47. Steininger TL, Wainer BH, Klein R, Barbacid M, Palfrey HC: High-affinity nerve growth factor receptor (Trk) immunoreactivity is localized in cholinergic neurons of the basal forebrain and striatum in the adult rat brain. Brain Res 612: 330-335, 1993
48. Suzuki T, Bogenmamm E, Shimada H, Stram D, Seeger RC: Lack of high-affinity nerve growth factor receptors in aggressive neuroblastomas. J Natl Cancer Inst 85: 377-384, 1993
49. Thoenen H, Barde YA: Physiology of nerve growth factor. Physiol Rev 60: 1284-1335, 1980
50. Towbin H, Staehelin T, Gordon J: Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc Natl Acad Sci U S A 16: 4350-4354, 1979
51. LNGFR regulates trk signal transduction and NGF-induced neuronal differentiation in MAH cells. Neuron 12: 733-745, 1994
52. Vetter ML, Martin-Zanca D, Parada LF, Bishop JM, Kaplan DR: Nerve growth factor rapidly stimulates tyrosine phosphorylation of phospholipase C-γ 1 by a kinase activity associated with the product of the trk protooncogene. Proc Natl Acad Sci U S A 88: 5650-5654, 1991
53. Vinores SA, Perez-Polo JR: Nerve growth factor and neuronal oncology. J Neurosci Res 9: 81-100, 1983
54. Yaeger MJ, Koestner A, Marushige K, Marushige Y: The reverse transforming effects of nerve growth factor on five human neurogenic tumor cell lines: In vitro results. Acta Neuropathol (Berl) 83: 72-80, 1991
55. Yan H, Schlessinger J, Chao M: Chimeric NGF-EGF receptors define domains responsible for neuronal differentiation. Science 252: 561-564, 1991
56. Yan Q, Johnson EM Jr: An immunohistochemical study of the nerve growth factor receptor in developing rats. J Neurosci 8: 3481-3498, 1988
57. Yanker BA, Schooter E: The biology and mechanism of action of nerve growth factor. Annu Rev Biochem 51: 845-868, 1982