Synaptic mechanisms of thiopental-induced alterations in synchronized cortical activity

Anesthesiology

Volumn 84, Issue 6, 1996, Pages 1425-1434

  Lukatch, Heath S ^a   MacIver, M Bruce ^a,b  

^a STANFORD UNIVERSITY   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anesthetics, barbiturates: thiopental; Brain: aminobutyric acid; hippocampus; neocortex; Monitoring, electroencephalogram: burst suppression; isoelectric electroencephalogram activity; oscillations; Monitoring, electroencephalographic frequency bands: alpha; delta; theta; Receptors: glutamate; muscarinic

Indexed keywords

4 AMINOBUTYRIC ACID; ATROPINE; BICUCULLINE; CARBACHOL; GLUTAMATE RECEPTOR; MUSCARINIC RECEPTOR; MUSCIMOL; THIOPENTAL;

ALPHA RHYTHM; ANESTHESIA LEVEL; ANESTHESIA MECHANISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DELTA RHYTHM; ELECTROCORTICOGRAPHY; HIPPOCAMPUS; INTRAVENOUS ANESTHESIA; MALE; NEOCORTEX; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SYNAPTIC TRANSMISSION; THETA RHYTHM;

ANESTHETICS, INTRAVENOUS; ANIMALS; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROENCEPHALOGRAPHY; MALE; MUSCIMOL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA; SYNAPSES; THIOPENTAL;

EID: 0029905454     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199606000-00019     Document Type: Article

References (57)

1. Nicoll RA, Eccles JC, Oshima T, Rubia F: Prolongation of hippocampal inhibitory postsynaptic potentials by barbiturates. Nature 1975; 258:625-26
2. Schulz DW, Macdonald RL. Barbiturate enhancement of GABA-mediated inhibition and activation of chloride ion conductance: Correlation with anticonvulsant and anesthetic actions. Brain Res 1981; 209:177-88
3. Barker JL, Mathers DA: GABA receptors and the depressant action of pentobarbital. Trends Neurosc 1981; 10-13
4. Dunwiddie TV, Worth TS, Olsen RW: Facilitation of recurrent inhibition in rat hippocampus by barbiturate and related nonbarbiturate depressant drugs. J Pharmacol Exp Ther 1986; 238(2):564-75
5. Olsen RW: Barbiturates. Int Anesthesiol Clin 1988; 26:254-61
6. ffrench-Mullen JM, Barker JL, Rogawski MA: Calcium current block by (-)-pentobarbital, phenobarbital, and CHEB but not (+)-pentobarbital in acutely isolated hippocampal CA1 neurons: Comparison with effects on GABA-activated Cl- current. J Neurosci 1993; 13(8):3211-21
7. Clark DL, Rosner BS: Neurophysiologic effects of general anesthetics. I. The electroencephalogram and sensory evoked responses in man. ANESTHESIOLOGY 1973; 38(6):564-82
8. Buhrer M, Maitre PO, Hung OR, Ebling WT, Shafer SL, Stanski DR: Thiopental pharmacodynamics. I. Defining the pseudo-steady-state serum concentration-EEG effect relationship. ANESTHESIOLOGY 1992; 77:226-36
9. Ebling WF, Danhof M, Stanski DR: Pharmacodynamic characterization of the electroencephalographic effects of thiopental in rats. J Pharmacokinet Biopharm 1991; 19(2):123-43
10. MacIver MB, Mandema JW, Stanski DR, Bland BH: Thiopental uncouples hippocampal and cortical synchronized EEG activity. ANESTHESIOLOGY 1996; 84:1411-24
11. Gustafsson LL, Ebling WF, Osaki E, Stanski DR: Quantitation of thiopental depth of anesthesia in the rat. ANESTHESIOLOGY 1996; 84:415-27
12. MacIver MB, Harris DP, Konopacki J, Roth SH, Bland BH: Carbachol induced rhythmical slow wave activity recorded from dentate granule neurons in vitro. Proc West Pharmacol Soc 1986; 29:159-61
13. MacVicar BA, Tse FwY: Local neuronal circuitry underlying cholinergic rhythmical slow activity in CA3 area of rat hippocampal slices. J Physiol (Lond) 1989; 417:197-212
14. Huerta PT, Lisman JE: Heightened synaptic plasticity of hippocampal CA1 neurons during a cholinergically induced rhythmic state. Nature 1993; 364:723-5
15. Konopacki J, Golebiewski H, Eckersdorf B: Carbachol-induced theta-like activity in entorhinal cortex slices. Brain Res 1992; 572: 76-80
16. Konopacki J, Bland BH, MacIver MB, Roth SH: Cholinergic theta rhythm in transected hippocampal slices: independent CA1 and dentate generators. Brain Res 1987; 436:217-22
17. Ebling WF, Mills-Williams L, Harapat SR, Stanski DR: High-performance liquid chromatographic method for determining thiopental concentrations in twelve rat tissues: Application to physiologic modeling of disposition of barbiturate. J Chromatogr 1989; 490: 339-53
18. Bland BH, Colom LV: Extrinsic and intrinsic properties underlying oscillation and synchrony in limbic cortex. Prog Neurobiol 1993; 41:157-208
19. Freund TF, Gulyas AI: GABAergic interneurons containing calbindin D28K or somatostatin are major targets of GABAergic basal forebrain afferents in the rat neocortex. J Comp Neurol 1991; 314: 187-99
20. Freund TF, Meskenaite V: gamma-Aminobutyric acid-containing basal forebrain neurons innervate inhibitory interneurons in the neocortex. Proc Natl Acad Sci USA 1992; 89:738-42
21. A responses in rat hippocampus. Neuron 1993; 10:189-200
22. MacIver MB, Kendig JJ: Anesthetic effects on resting membrane potential are voltage-dependent and agent specific. ANESTHESIOLOGY 1991; 74:83-8
23. MacIver MB, Tauck DL, Kendig JJ: General anaesthetic modification of synaptic facilitation and long-term potentiation in hippocampus. Br J Anaesth 1989; 62:301-10
24. Lysakowski A, Wainer BH, Bruce G, Hersh LB: An atlas of the regional and laminar distribution of choline acetyltransferase immunoreactivity in rat cerebral cortex. Neuroscience 1989; 28:291-336
25. Zilles KJ: The cortex of the rat, A Stereotaxic Atlas. New York, Springer, 1985
26. Feenstra BW, Holsheimer J: Dipole-like neuronal sources of theta rhythm in dorsal hippocampus, dentate gyrus and cingulate cortex of the urethane-anesthetized rat. Electroencephalogr. Clin Neurophysiol 1979; 47:532-8
27. Holsheimer J: Generation of theta activity (RSA) in the cingulate cortex of the rat. Exp Brain Res 1982; 47:309-12
28. Collingridge GL, Kehl SJ, McLennan H: Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus. J Physiol (Lond) 1983; 334:33-46
29. Nicoll RA, Malenka RC, Kauer JA: Functional comparison of neurotransmitter receptor subtypes in mammalian central nervous system. Physiol Rev 1990; 70:513-65
30. Anis NA, Berry SC, Burton NR, Lodge D: The dissociative anaesthetics, ketamine and pheneyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspanate. Br J Pharmacol 1983; 79:565-75
31. Kullmann DM, Martin RL, Redman SJ: Reduction by general anaesthetics of group Ia excitatory postsynaptic potentials and currents in the cat spinal cord. J Physiol (Lond) 1989; 412:277-96
32. Barker JL: Selective depression of postsynaptic excitation by general anesthetics, Molecular Mechanisms of Anesthesia, Progress in Anesthesiology. Edited by Fink BR. New York, Raven, 1975, pp 135-53
33. Gage PW, Robertson B: Prolongation of inhibitory postsynaptic currents by pentobarbitone, halothane and ketamine in CA 1 pyramidal cells in rat hippocampus. B. J Pharmacol 1985; 85: 675-81
34. A-mediated neuronal inhibition. Ann N Y Acad Sci 1991; 625:91-6
35. Jones MV, Harrison NL: Effects of volatile anesthetics on the kinetics of inhibitory postsynaptic currents in cultured rat hippocampal neurons. J Neurophysiol 1993; 70:1339-49
36. Sato M, Austin GM, Yai H: Increase in permeability of the postsynaptic membrane to potassium produced by 'nembutal.' Nature 1967; 215:1506-8
37. Berg-Johnsen J, Langmoen IA: Mechanisms concerned in the direct effect of isotlurane on rat hippocampal and human neocortical neurons. Brain Res 1990; 507:28-34
38. Nicoll RA, Madison DV: General anesthetics hyperpolarize neurons in the vertebrate central nervous system. Science 1982; 217: 1055-7
39. MacIver MB, Roth SH: Inhalation anaesthetics exhibit pathway-specific and differential actions on hippocampal synaptic responses in vitro. Br J Anaesth 1988; 60:680-91
40. Kissin I, Mason JOd, Bradley EL, Jr: Pentobarbital and thiopental anesthetic interactions with midazolam. ANESTHESIOLOGY 1987; 67: 26-31
41. Kissin I: General anesthetic action: an obsolete notion? Anesth Analg 1993; 76:215-8
42. A receptor/chloride channel complex in anesthesia. ANESTHESIOLOGY 1993; 78:757-76
43. Bland BH: The physiology and pharmacology of hippocampal formation theta rhythms. Prog Neurobiol 1986; 26:1-54
44. Schwartzkroin PA: Hippocampal slices in experimental and human epilepsy. Adv Neurol 1986; 44:991-1010
45. Jennum P, Dam M, Fuglsang-Frederiksen A. Effect of barbiturate on epileptiform activity: Comparison between intravenous and oral administration. Sphenoidal, zygomatic and temporal recordings. Acta Neurol Scand 1993; 88:284-8
46. Mori K: Excitation and depression of CNS electrical activities induced by general anesthetics, Proceedings of 5th World Congress of Anaesthesiology. Edited by Miyasaki M, Iwatsuki K, Fujita M. Amsterdam, Excerpta Medica, 1973, pp 40-53
47. Reddy RV, Moorthy SS, Mattice T, Dierdorf SF, Deitch R, Jr: An electroencephalographic comparison of effects of propofol and methohexital. Electroencephalogr Clin Neurophysiol 1992; 83:162-8
48. Tomoda K, Shingu K, Osawa M, Murakawa M, Mori K: Comparison of CNS effects of propofol and thiopentone in cats. Br J Anaesth 1993; 71:383-7
49. B receptor-mediated presynaptic inhibition in the hippocampus in vitro. J Neurophysiol 1989; 61:524-33
50. Steriade M, Amzica F, Contreras D. Cortical and thalamic cellular correlates of electroencephalographic burst-suppression. Electroencephalogr Clin Neurophysiol 1994; 90:1-16
51. Hille B: Classical Biophysics of the squid giant axon, Na and K channels of axons, calcium channels, Ionic Channels of Excitable Membranes. Sunderland, Sinauer Associates, 1992, pp 43, 59-81, 101-4
52. Swank RL: Synchronization of spontaneous electrical activity of cerebrum by barbiturate narcosis. J Neurophysiol 1949; 12:161-72
53. Henry CE, Scoville WB: Supression-burst activity from isolated cerebral cortex in man. Electroencephalogr Clin Neurophysiol 1952; 4:1-22
54. Steriade M, McCormick DA, Sejnowski TJ: Thalamocortical oscillations in the sleeping and aroused brain. Science 1993b; 262: 679-85
55. Steriade M, Contreras D, Curro Dossi R, Nunez A: The slow (<1 Hz) oscillation in reticular thalamic and thalamocortical neurons: scenario of sleep rhythm generation in interacting thalamic and neocortical networks. J Neurosci 1993a; 13:3284-99
56. Rainnie DG, Grunze HC, McCarley RW, Greene RW: Adenosine inhibition of mesopontine cholinergic neurons: implications for EEG arousal. Science 1994; 263:689-92
57. Schneider J, Thomalske G: Exploration pharmacodynamique cortico-sous-corticale et ses criteres electrographiques. La determination d'un foyer lesionnel chez l'homme par la technique pentatholique. Electroencephalogr Clin Neurophysiol 1956; 8: 353-69