T cell involvement in glomerular injury

Kidney and Blood Pressure Research

Volumn 19, Issue 5, 1996, Pages 298-304

  Merkel, F ^a   Marx, M ^b   Netzer, K O ^b   Weber, M ^a  

^a UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Autoimmunity; Glomerulonephritis; Goodpasture s syndrome; Immunosuppressive therapy; Interstitial nephritis; T cells

Indexed keywords

AUTOIMMUNITY; CELLULAR IMMUNITY; DISEASE COURSE; ETIOLOGY; GLOMERULOPATHY; GOODPASTURE SYNDROME; IMMUNOSUPPRESSIVE TREATMENT; INTERSTITIAL NEPHRITIS; PATHOGENESIS; PRIORITY JOURNAL; PROGNOSIS; REVIEW; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

EID: 0029905175     PISSN: 14204096     EISSN: 14230143     Source Type: Journal    
DOI: 10.1159/000174090     Document Type: Article

References (69)

1. Davis MM, Bjorkmann PJ: T-cell antigen receptor genes and T-cell recognition, Nature 1988: 334:395-401.
2. Romagnani S: Induction of Till and TH2 responses: A key role for 'natural' immune response? Immunol Today 1992:13:379-381.
3. Salgame P, Abrams JS, Calyberger C, Goldstein H, Convit J, Modlin RL, Bloom HR: Differing lymphokine proti les of functional subsets of human CD4 and CDS T cell clones, Science 1991;290:279-282.
4. Bruciale TJ, Brachiale VL: Antigen presentation: Structural themes and functional variations, Immunol Today 1991:12:124-129.
5. Oliveira DBG, Peters DK: Autoimmunity and the kidney, Kidney Int 1989:35:923-928.
6. Li IlL, Hancock WW, Hooke Dll, Dowling JP, Atkins RC: Mononuclear cel I activation and decreased renal function in IgA nephropathy with crescents, Kidney Int 1990:37:1552- 1556.
7. Roy-Chaudhury P, Wu B, McDonald S, I laites NE, Simpson JG, Power DA: Phenotypic analysis of the glomerular and periglomcrular mononuclear cell infiltrates in the Thy 1.1 model of glomerulonephritis, Lab Invest 1995:72:524-531.
8. Garcia del Moral R, Gomcv-Moralcs VI, Cortes V, Aguayo ML, Gigosos RL, Larde H i P, Navas A, Anciros J, Aguilar D: Mononuclear cell subsets in IgM mesangial proliferative glomerulonephritis, A comperative study with minimal change nephrotic syndrome and immunonega-tive mesangial proliferative glomerulonephritis, Nephron 1993:65:215-22 L
9. Saito T, Atkins RC: Contribution of mononuclear leukocytes to the progression of experimental focal glomerular sclerosis, Kidney Int 1990:37:1076-1083.
10. Markovie-Lipkovski J, Müller CA, Bohlc A: Mononuclear leukocytes, expression of 11 LA class II antigens and intercellular adhesion molecule I in focal segmental glomerulosclerosis, Nephron 1991;59:286-293.
11. Bottazo GF, Todd I, Mirkian R, Bclfiore A, Pujol-Borell R: Organ-specific autoimmunity: A 1986 overview, Immunol Rev 1986:94:137-169.
12. Wuthrich RP, Yui MA, Mazoujian G, Nabavi N, Glimchcr LH, Kelley VE: Enhanced MHC class II expression in renal proximal tubules precedes lossof renal function in MRl./lprmice with lupus nephritis, Am J Pathol 1989; 134:45-51.
13. Müller CA, Markovie-Lipkovski J, Risler T, Bohme A, Müller GA: Expression of HLA-DQ, DR and DP antigens in normal kidney and glomerulonephritis, Kidney Int 1989:35:116-124.
14. Benson EM, Colvin RB, Russell PS: Induction of la antigens in murine renal transplants, J Immunol 1985:134:7-9.
15. Wuthrich RP, Jevnikar AM, Takci I., Glimchcr LII, Kelley VE: Intercellular adhesion molecule-1 (ICAM-I) is uprcgulated in autoimmune lupus nephritis, Am J Pathol 1990; 136:441-450.
16. Wuthrich RP, Jenkins TA, Snyder TS: Regulation of cytokine stimulated vascular cell adhesion molecule-1 expression in renal tubular epithelial cells, Transplantation 1993:55:172 176.
17. Jevnikar AM, Brennan DC, Singer GG, Hong JE, Maslinski W, Wuthrich RP, Glimchcr LIT Kelley VE: Stimulated kidney tubular epithelial cells express membrane associated and secreted TNFa, Kidney Int 1991;40:203-211.
18. Schmouder RL, Stricter RM, Wiggins RC, Chensuc SW, Kunkel SL: In vitro and in vivo interlcukin-8 production in human renal conical epithelial cells, Transplantation 1992:55: 191-198.
19. Thompson NL, Flanders KC, Smith JM, F.l-lingsworth LR, Roberts AB, Sporn MB: Impression of transforming groth factor-p I in spe-cific cells and tissue ofadult and neonatal mice, Cell Biol 1989:108:661-669.
20. Radeke fill, Emmendorffer A, Ueieehowski P, von der Ohe J, Schwinzer B, Resell K: Activation of autoreactive l-lymphocytcs by cultured syngeneic glomerular mesangial cells, Kidney Ini 1994;45:763-774.
21. Singer GG, Yokoyama H, Bloom RD, Jevnikar AM, Nabavi N, Kelley VR: Stimulated renal tubular epithelial cells induce anergy in CD4+ T cells, Kidney Int 1993:44:1030-1035.
22. Ncilson EC: Is immunological tolerance of self modulated through antigen presentation by parenchymal epithelium? Kidney Int 1993:44: 927 931.
23. Miller J: T-Cell Tolerance to Self Antigen, Immunology, cd 3, London, Mosby-Year Book, 1993, pp 10.1 10.10.
24. Hagerty DH, Allen P: Processing and presentation of self and foreign antigens by the renal proximal tubule, J Immunol 1992:148:2324 2330.
25. Bohle A, Wehrmann M, Mackensen-Haen S, Gise H, Mickeler E, Xiao TC, Müller C, Müller GA: Pathogenesis of chronic renal failure in primary glomerulopathies, Nephrol Dial Transplant 1994;9(suppl 3):4 12.
26. Schwartz RH: A cell culture model for T lymphocyte clonal anergy, Science 1990:248: 1349-1356.
27. Falk MC, Ng G, Zhang GY, Fanning GC, Roy LP, Bannister KM, T homas AC, Clarkson AR, Woodroffe AJ, Knight .IF: Infiltration of the kidney by alpha beta and gamma delta T cells: Effect on progression in IgA nephropathy, Kidney Int 1995:47:177-185.
28. Lai KN, Mo RT, Lai CK, Chan CIT, Li PK: Increase of both circulating Till and Th2 T lymphocyte subsets in IgA nephropathy, Clin Exp Immunol 1994;96:116-121.
29. Lai KN, Ho RT, Leung JC, Chili YL, Lim PL, Lui SF, Li PK: CD4-positivecells from patients w ith IgA nephropathy demonstrate increased mRNA of cytokines that induce the IgA switch and differentiation, .J Pathol 1994:174:13-22.
30. Nakamura T, Ebihara I, Takahashi T, Yamamoto M, Tomino Y, Koidc II: Increased IL-6mRNA expression by peripheral blood T cells from patients with IgA nephropathy, Autoimmunity 1993;15:171-179.
31. Hudson BG, VVieslander J, Wisdom BJ, Noel-ken ME: Goodpasture syndrome: Molecular architecture and function of basement membrane antigen, Lab Invest 1989:61:256-269.
32. Saus J, Wieslander J, Langeveld JPM, Quinones S, Hudson BG: Identification of Good-pasture antigen as the α3(IV) chain of collagen IV J Biol Chem 1988:263:13374-13380.
33. Neale TJ, Tipping PG, Carson SD, Holdsworth SR: Participation of cell-mediated immunity in deposition of fibrin in glomerulonephritis, Lancet 1988:6:421-424, '
34. Huey B, McCormick K, Capper J, Ratcliff C, Colombc BW, Garovoy MR, Wilson CB: Associations of MLA-DR and HLA-DQ types w ith anti-GBM nephritis by sequence-specific oligonucleotide probe hybridization, Kidney Int 1993:44:307-312.
35. Rees AJ: The immunogeneties of glomerulonephritis, Kidney Int 1994:45:377 383.
36. Bolton WK, Tucker IT, Sturgill BC: New avian model of experimental glomerulonephritis consistent with mediation by cellular immunity, J Clin Invest 1984;73:1263 1276.
37. Bolton WK, Chandra M, Tyson TM, Kirkpatrick PR, Sadovnic MJ, Sturgill BC: Transfer of experimental glomerulonephritis in chickens by mononuclear cells, Kidney Int 1988:34:598 610.
38. Bolton WK, May WJ, Sturgill BC: Proliferative autoimmune glomerulonephritis in rats: A model for autoimmune glomerulonephritis in humans, Kidney Int 1993:44:294-306.
39. Tipping PG, Neale TJ, Holdsworth SR: T lymphocyte participation in antibody-induced experimental glomerulonephritis, Kidney Int 1985:27:530-537.
40. Reynolds J, Sallie BA, Syrganis C, Pusey CD: The role of T-helper lymphocytes in priming for experimental autoimmune glomerulonephritis in the BN rat, J Autoimmun 1993:6:571-585.
41. Huang XR, Holdsworth SR, Tipping PG: Evidence for delayed type hypersensitivity mechanisms in glomerular crescent formation, Kidney Int 1994:46:69-78.
42. Derry C.I, Ross CN, Lombardi G, Mason PD, Rees AJ, Lechler RI, Pusey CD: Analysis of Tcell responses to autoantigen in Goodpasture’s disease, Clin Exp Immunol 1995:100: 262-268.
43. Merkel F, Kalluri R, Marx M, Enders U, Steva-novic S, Giegerich G, Ncilson N, Rammenscc HG, Hudson BG, Weber M: Autoreactive T-cells in Goodpasture’s syndrome recognize the N-terminal NCI domain on α3 type IV collagen, Kidney Int 1996:49:1127 1133.
44. Lockwood CM: Immunoregulation of autoimmune responses in systemic vasculitis; in Cou-tinho A, Kazatchkine MD (eds): Autoimmunity, Physiology and Disease, New York, Wiley-Liss, 1993, pp 307-314.
45. Van der Woude F.I, Van Es LA, Daha MR: The role of the c-ANCA antigen in the pathogenesis of Wegener's granulomatosis, A hypothesis based on both humoral and cellular mecha-nsims, Nelli J Med 1990:36:169-171.
46. Mathieson PW, Thiru S, Olivcra DBG: Mercuric chloride-treated Brown Norway rats develop widespread tissue injury including necrotizing vasculitis, Lab Invest 1992:67:121-129.
47. Goldmann M, Lambert PH: Cellular and molecular aspects of systemic autoimmunity: in Cou-tinho A, Kazatchkine MD (eds): Autoimmunity, Physiology and Disease, New York, Wiley-Liss, 1993, pp 407-422.
48. Wu J, Zhou T, Zhang J, He J, Gause WC, Mountz JD: Correction of accelerated autoimmune disease by early replacement of the mutated Ipr gene with the normal Fas apoptosis gene in the Tcells of transgenic MRL-lpr Ipr mice, Proc Natl Acad Sci 1994:91:2344-2348.
49. Alexopoulos E, Leontsini M, Papadimitriou M: Relationship between interstitial infiltrates and steroid responsiveness of proteinuria in membranous nephropathy, Nephrol Dial Transplant 1994;9:623-629.
50. Soma J, Sailo T, Sato H, Ootaka T, Scino J, Fur-uta T, Abe K: Intraglomerular immune cell infiltration and complement 3 deposits in mcm-branoproliferative glomerulonephritis type I: A serial-biopsy study of 25 cases, Am J Kidney Dis 1994:23:365 373.
51. Sewell RF, Short CD: Minimal-change nephropathy: flow does the immune system affect the glomerulus? Nephrol Dial Transplant 1993:8: 108-116.
52. Koyama A, Fujisaki M, Kobayashi M: A glomerular permeability lactor produced by human T-cell hybridomas, Kidney Int 1991:40: 453-457.
53. Savin VJ, Artero M, Sharma R, Sharma M: Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis, N Engl J Med 1996;334:878-881.
54. Nath KA: Tubulo interstitial changes as a major determinant in the progression of renal damage, Am J Kidney Dis 1992;20:1-17.
55. Abe S, Amagasaki Y, lyori S, Konishi K, Kato E, Sakaguchi 11: Significance of tubulointerstitial lesions in biopsy specimens of glomerulonephritis patients, Am J Nephrol 1989;9:30-37.
56. Kelly CJ, Haverty TP: Mechansims of interstitial nephritis; in Jacobson HR, Striker GE, Klahr S (eds): The Principles and Practice of Nephrology, Philadelphia, Decker, 1991, pp 344-348.
57. Grcevska L, Polenakovic M: Tubular and interstitial lesions and mononuclear cell infiltration in primary forms of glomerulonephritis, Ren Fail 1993;15:485-493.
58. Colombo V, Confalonicri R, Veronese S, Mino-la E, Falcri M, Grille C, Minetti L: Interstitial leucocyte infiltration in primary glomerulonephritis: Extent and composition analysis, Ren Fail 1993:15:451-459.
59. Ncilson EG, McCafferty E, Feldman A, dayman MD, Zakheim B, Korngold R: Spontaneous interstitial nephritis in kdkd mice, I, An experimental model of autoimmune renal disease, J Immunol 1984:133:2560 2565.
60. Kelly CJ, Korngold R, dayman M, Mann R, Ncilson EG: Spontaneous interstitial nephritis in kdkd mice, II, Characterization of a tubular antigen-specific, H-2K restricted Lyt2* effector Tcell mediating destructive tubulointerstitial injury, J Immunol 1986:136:526-531.
61. Ncilson EG, Sun MJ, Kelly CJ, Hines WH, Haverty TP, Clayman MD, Cooke N: Molecular characterization of a major nephritogenic domain in the autoantigen of anti-tubular basement membrane disease, Proc Natl Acad Sci 1991:88:2006-2010.
62. Neilson EG: The nephritogenic T lymphocyte response in interstitial nephritis, Semin Nephrol 1993:13:496 502.
63. Hceger PS, Smoyer WE, Saad T, Albert S, Kelly CJ, Neilson EG: Molecular analysis of the helper T cell response in murine interstitial nephritis, .I Clin Invest 1994:94:2084 2092.
64. Sharma K, Xiyaileh FN: The transforming growth factor-fl system and the kidney, Semin Nephrol 1993;13:116-128.
65. Sturtz F, Neilson EG: The role of lymphocytes in the progression of interstitial disease, Kidney Int 1994;45:SI06-SI10.
66. Reynolds J, Puscy CD: In vivo treatment with a monoclonal antibody to T helper cells in experimental autoimmune glomerulonephritis in the BN rat, Clin Exp Immunol 1994:95:122-127.
67. Weiner HE, Maekin GA, Matsui M, Orav EJ, Khoury SJ, Dawson DM, Haller DA: Double-blind pilot trial of oral tolerization with myelin antigens in multiple sclerosis, Science 1993: 259:1321 1324.
68. Trentham DE, Dynesius-frentham RA, Orav EJ, Combitchi D, Lorenzo C. Sewell KL, Hafler DA, Weiner ML: Effects of oral administration of type II collagen on rheumatoid arthritis, Science 1993:261: 1727-1730.
69. Sayegli MH, Turka LA: Tecll costimulatory pathways: Promising novel targets for immunosuppression and tolerance induction, J Am Soc Nephrol 1995:6:1143-1150.