Interferon-gamma plays a key role in the human mixed lymphocyte culture

Bone Marrow Transplantation

Volumn 18, Issue 5, 1996, Pages 991-996

  Danzer, S G ^a   Acampo, C ^a   Rink, L ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

BMT; Cytokines; IFN ; MLC; Transplantation

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BONE MARROW TRANSPLANTATION; CELL ACTIVITY; CONTROLLED STUDY; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; LYMPHOCYTE COUNT; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MIXED LYMPHOCYTE CULTURE; MIXED LYMPHOCYTE REACTION; MONOCYTE; NORMAL HUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ANTIGENS, CD; BONE MARROW TRANSPLANTATION; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; HUMANS; INTERFERON TYPE II; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; RECEPTORS, INTERFERON;

EID: 0029905156     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Danzer SG, a Campo C, Kunze B et al. Identification of HLA-DRB1 and HLA-DQB1 identical individuals by a cytokine-based mixed lymphocyte culture. Lymphokine Cytokine Res 1994; 13: 303-308.
2. Bishihara A, Kedar E, Leshem B et al. A 2-day MLC procedure for marrow donor selection for allogeneic bone marrow transplantation. Eur J Immunogen 1993; 20: 289-292.
3. Maraskovsky E, Chen WF, Shortman K. IL-2 and IFN-gamma are two necessary lymphokines in the development of cytolytic T cells. J Immunol 1989; 143: 1210-1214.
4. Wong GH, Clark-Lewis I, McKimm-Breschkin et al. Interferon-gamma induces enhanced expression of 1a and H-2 antigens on B lymphoid, macrophage, and myeloid cell lines. J Immunol 1983; 131; 788-793.
5. Weigent DA, Stanton GJ, Johnson HM. Interleukin 2 enhances natural killer cell activity through induction of gamma interferon. Infect Immun 1983; 41: 992-997.
6. Kasahara T, Hooks JJ, Dougherty SF, Oppenheim JJ. Interleukin 2-mediated immune interferon (IFN-gamma) production by human T cells and T cell subsets. J Immunol 1983; 130: 1784-1789.
7. Philip R, Epstein LB. Tumor necrosis factor as immunomodulator of monocyte cytotoxicity induced by itself, gamma-interferon and interleukin 1. Nature 1986; 323: 86-89.
8. Rodriguez MA, De Sanctis JB, Blasini AM et al. Human IFN-γ up-regulates IL-2 receptors in mitogen-activated T lymphocytes. Immunology 1990; 69: 554-557.
9. Gifford GE, Tibor A, Peavy DL. Interferon production in mixed lymphocyte cell cultures. Infect Immun 1971; 3: 164-166.
10. Kirchner H, Zawatzky R, Schirrmacher V. Interferon production in the murine mixed lymphocyte culture. I. Interferon production caused by differences in the H-2 K and H-2 D region but not by differences in the I region or the M locus. Eur J Immunol 1979; 9: 97-99.
11. Kirchner H, Zawatzky R, Engler H et al. Production of interferon in the murine mixed lymphocyte culture. II. Interferon production is a T cell-dependent function, independent of proliferation. Eur J Immunol 1979; 9: 824-826.
12. Puré E, Inaba K, Metlay J. Lymphokine production by murine T cells in the mixed leukocyte reaction. J Exp Med 1988; 168: 795-800.
13. Manger B, Kalden JR, Zawatzky R, Kirchner H. Interferon production in the human mixed lymphocyte culture. Transplantation 1981; 32: 149-152.
14. Perussia B, Mangoni L, Engers HD, Trinchieri G. Interferon production by human and murine lymphocytes in response to alloantigens. J Immunol 1980; 125: 1589-1595.
15. Cantell K, Koskimies S, Hirvonen S. Production of interferon in mixed leukocyte cultures from two individuals. J Interferon Res 1990; 10: 331-335.
16. Ilonen J, Karttunen R. The production of interleukin 2 as a measure of reactivity in mixed lymphocyte culture. Immunobiology 1984; 167: 399-403.
17. Stuber G, Vánky F, Pócsik E et al. Expression of interleukin-2 receptor on blood lymphocytes stimulated with allogeneic lymphocytes or autologous tumor cells. Cancer Immunol Immunother 1990; 31: 76-80.
18. Degiannis D, Czarnecki M, Hornung N et al. Mixed lymphocyte reaction-induced release of soluble IL-2 receptor. Transplantation 1991; 51: 518-523.
19. Bucy RP, Hanto DW, Berens E, Schreiber RD. Lack of an obligate role for IFN-γ in the primary in vitro mixed lymphocyte response. J Immunol 1988; 140: 1148-1152.
20. Novelli F, Giovarelli M, Reber-Liske R et al. Blockade of physiologically secreted IFN-γ inhibits human T lymphocyte and natural killer cell activation. J Immunol 1991; 147: 1445-1452.
21. Danzer SG, Kirchner H, Rink L. Cytokine interactions in human mixed lymphocyte culture. Transplantation 1994; 57: 1638-1642.
22. Reem GH, Yeh NH. Interleukin 2 regulates expression of its receptor and synthesis of gamma interferon by human T lymphocytes. Science 1984; 225: 429-430.
23. Grabstein K, Dower S, Gillis S et al. Expression of interleukin 2, interferon-γ, and the IL-2 receptor by human peripheral blood lymphocytes. J Immunol 1986; 136; 4503-4508.
24. Rink L, Kruse A, Nicklas W et al. Induction of cytokines in human peripheral blood and spleen cells by the mycoplasma arthritidis-derived superantigen. Lymphokine Cytokine Res 1992; 11: 105-108.
25. Shalaby MR, Espevik T, Rice GC et al. The involvement of human tumor necrosis factors-α and -β in the mixed lymphocyte reaction. J Immunol 1988; 141: 499-503.
26. Munoz Fernandez MA, Fernandez MA, Fresno M. Synergism between tumor necrosis factor-alpha and interferon-gamma on macrophage activation for the killing of intracellular trypanosoma crusi through a nitric oxide-dependent mechanism. Eur J Immunol 1992; 22: 301-307.
27. Tsujimoto M, Yip JK, Vilcek J. Interferon-gamma enhances expression of cellular receptors for tumor necrosis factor. J Immunol 1986; 136: 2441-2447.
28. Malinowski K, Pullis C, Raisbeck AP, Rapaport FT. Modulation of human lymphocyte marker expression by gamma irradiation and mitomycin C. Cell Immunol 1992; 143: 368-377.
29. Carel JC, Schreiber RD, Falqui L, Lacy PE. Transforming growth factor beta decreases the immunogenicity of rat islet xenograft (rat to mouse) and prevents rejection in association with treatment of the recipient with a monoclonal antibody to interferon gamma. Proc Natl Acad Sci USA 1990; 87: 1591-1595.
30. Didlake RH, Kim EK, Sheehan K et al. Effect of combined anti-gamma interferon antibody and cyclosporine therapy on cardiac allograft survival in the rat. Transplantation 1988; 45: 222-223.
31. Landolfo S, Cofano F, Giovarelli M et al. Inhibition of interferon-gamma may suppress allograft reactivity by T lymphocytes in vitro and in vivo. Science 1985; 229: 176-179.
32. Rosenberg AS, Finbloom DS, Maniero TG et al. Specific prolongation of MHC class II disparate skin allografts by in vivo administration of anti-IFN-γ monoclonal antibody. J Immunol 1990; 144: 4648-4650.
33. Noronha IL, Eberlein-Gonska M, Hartley B et al. In situ expression of tumor necrosis factor-alpha, interferon-gamma, and interleukin-2 receptors in renal allograft biopsies. Transplantation 1992; 54: 1017-1024.
34. Dickinson AM, Sviland L, Dunn J et al. Demonstration of direct involvement of cytokines in graft-versus-host reactions using an in vitro human skin explant model. Bone Marrow Transplant 1991; 7: 209-216.