In vitro and in vivo antitumor activity of a novel nucleoside, 4'-thio- 2'-deoxy-2'-methylidenecytidine

Biological and Pharmaceutical Bulletin

Volumn 19, Issue 10, 1996, Pages 1311-1315

  Miura, Shinji ^a,b   Tanaka, Motohiro ^a   Yoshimura, Yuichi ^b   Satoh, Hiroshi ^b   Sakata, Shinji ^b   Machida, Haruhiko ^b   Matsuda, Akira ^c   Sasaki, Takuma ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b YAMASA CORPORATION   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

3(3,4 dimethyl thiazol 2 yl) 2,5 diphenyltetrazolium bromide (MTT) assay; 4' thio 2'deoxy 2' methylidenecytidine (4' thio DMDC); human tumor xenograft; nucleoside agent; solid tumor

Indexed keywords

4' THIO 2' DEOXY 2' METHYLIDENECYTIDINE; CYTARABINE; CYTIDINE DERIVATIVE; NUCLEOSIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLADDER CARCINOMA; CANCER CHEMOTHERAPY; CELL KILLING; CROSS RESISTANCE; DEAMINATION; DNA SYNTHESIS; GROWTH INHIBITION; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS REGULATION; TUMOR GROWTH;

EID: 0029905103     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.19.1311     Document Type: Article

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