Effects of structural changes on retinoid cytotoxicity in the CHO clonal assay

In Vitro and Molecular Toxicology: Journal of Basic and Applied Research

Volumn 9, Issue 2, 1996, Pages 173-181

  Oda, Roger M ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ESTERASE; OCTANOL; RETINOIC ACID; RETINOID;

ANIMAL CELL; ARTICLE; CELL CULTURE; CHO CELL; COLONY FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; LIPOPHILICITY; NONHUMAN;

EID: 0029904480     PISSN: 10979336     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

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2. ARMSTRONG, R.B., ASHENFELTER, K.O., ECKHOFF, C., LEVIN, A.A., and SHAPIRO, S.S. (1994). General and reproductive toxicology of retinoids, in: The Retinoids, Biology, Chemistry, and Medicine, 2nd ed. M.B. Sporn, A.B. Roberts, and D.S. Goodman (eds.) Raven Press: NY, pp. 545-572.
3. BEARD, R.L., GIL, D.W., MARLER, D.K., HENRY, E., COLON, D.F., GILLETT, S.J., AREFIEG, T., BREEN, T.S., KRAUSS, H., DAVIES, P.J.A., and CHANDRARATNA, R.A.S. (1994). Structural basis for the differential RXR & RAR activity of stilbene retinoid analogues. Bioorg. Med. Chem. Lett. 4, 1447-1452.
4. BENBROOK, D., LERNHARDT, E., and PFAHL, M. (1988). A new retinoic acid receptor identified from a hepatocellular carcinoma. Nature (London) 333, 669-672.
5. BENSON, J., ROYER, R., GALVIN, J., and SHIMIZU, R. (1983). Metabolism of phenanthridine to phenthridone by rat lung and liver microsomes after induction with benzo[a]pyrene and aroclor. Toxicol. Appl. Pharmacol. 68, 36-42.
6. BRAND, N., PETKOVICH, M., KRUST, A., CHAMBON, P., DE THE, H., MARCHIO, A., TIOLLAIS, P., and DEJEAN, A. (1988). Identification of a second human retinoic acid receptor. Nature (London) 332, 850-853.