Neonatal exposure to 2,2′,5,5′-tetrachlorobiphenyl causes increased susceptibility in the cholinergic transmitter system at adult age

Environmental Toxicology and Pharmacology

Volumn 1, Issue 3, 1996, Pages 217-220

  Eriksson, Per ^a   Fredriksson, Anders ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Behavior; Cholinergic; Developmental neurotoxicity; Neonatal; PCB (polychlorinated biphenyl)

Indexed keywords

ANIMALIA;

CHOLINERGIC RECEPTOR STIMULATING AGENT; DEXAMPHETAMINE; NICOTINE TARTRATE; NICOTINIC RECEPTOR; POLYCHLORINATED BIPHENYL; TETRACHLOROBIPHENYL;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; DOSE RESPONSE; EXPOSURE; HABITUATION; LOCOMOTION; MALE; MOTOR ACTIVITY; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEUROTOXICITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0029904363     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/1382-6689(95)00017-8     Document Type: Article

References (14)

1. Archer, T., A. Fredriksson, G. Jonsson, T. Lewander, A.K. Mohammed, S.B. Ross and U. Söderberg, 1986, Central noradrenaline depletion antagonizes aspects of d-amphetamine-induced hyperactivity in the rat, Psychopharmacology 88, 141.
2. Archer, T., A. Fredriksson, T. Lewander and U. Söderberg, 1987, Marble burying and spontaneous motor activity in mice: interactions over days and the effect of diazepam, Scand. J. Psycho. 28, 242.
3. Eriksson, P. and A. Fredriksson, 1996, Developmental neurotoxicity of four ortho-substituted polychlorinated biphenyls in the neonatal mouse, Environ. Toxicol. Pharmacol. 1, 155.
4. Falkeborn, Y., C. Larsson, A. Nordberg and P. Slanina, 1983, A comparison of the regional ontogenesis of nicotine- and muscarine-like binding sites in the mouse brain, Int. J. Dev. Neurochem. 1, 187.
5. Fiedler, E.P., M.J. Marks and A.C. Collins, 1987, Postnatal development of cholinergic enzymes and receptors in mouse brain, J. Neurochem. 49, 983.
6. Jacobson, J.L., S.W. Jacobson and H.E.B. Humphrey, 1990, Effects of in utero exposure to polychlorinated biphenyls and related contaminants on cognitive functioning in young children, J. Pediatr. 116, 38.
7. Jensen, S., 1966, Report of a new chemical hazard, New Scientist 32, 612.
8. Kirk, R.E., 1968, Experimental Design; Procedures for Behavioural Sciences (Brooks/Cole, Belmont, CA).
9. Nordberg, A., 1993, Neuronal nicotinic receptors and their implications in ageing and neurodegenerative disorders in mammals, J. Reprod. Fert., Suppl. 46, 145.
10. Nordberg, A., X. Zang, A. Fredriksson and P. Eriksson, 1991, Neonatal nicotine exposure induces permanent changes in brain nicotinic receptors and behaviour in adult mice, Dev. Brain Res. 63, 201.
11. Rogan, W.J., B.C. Gladen, K.L. Hung, S.L. Koong, L.Y. Shia, J.S. Taylor, Y.C. Wu, D. Yang, N.B. Ragan and C.C. Hsu, 1988, Congenital poisoning by polychlorinated biphenyls and their contaminants in Taiwan, Science 241, 334.
12. Seegal, R.F. and W. Shain, 1992, Neurotoxicity of polychlorinated biphenyls. The role of ortho-substituted congeners in altering neurochemical function, in: The Vulnerable Brain and Environmental Risks, ed. R.L. Isaacson and K.F. Jensen (Plenum Press, New York) Vol. 2, p. 169.
13. Tilson, H.A. and G.J. Harry, 1994, Developmental neurotoxicology of polychlorinated biphenyls and related compounds, in: The vulnerable brain and environmental risks, ed. R.L. Isaacson and K.F. Jensen (Plenum Press, New York) Vol. 3, p. 267.
14. Tilson, H.A., J.L. Jacobson and W.J. Rogan, 1990, Polychlorinated biphenyls and the developing nervous system: cross-species comparisons, Neurotox. Teratol. 12, 239.