Single photon emission computed tomography in psychiatry: Current perspectives

Harvard Review of Psychiatry

Volumn 4, Issue 1, 1996, Pages 27-38

  Vasile, Russell G ^a,b  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFFECTIVE NEUROSIS; BRAIN BLOOD FLOW; BRAIN SCINTISCANNING; DEMENTIA; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; HUMAN; PRIORITY JOURNAL; REVIEW; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; THREE DIMENSIONAL IMAGING;

EID: 0029904342     PISSN: 10673229     EISSN: None     Source Type: Journal    
DOI: 10.3109/10673229609030519     Document Type: Review

References (91)

1. Rauch SL, Renshaw PF. Clinical neuroimaging in psychiatry. Harvard Rev Psychiatry 1995;2:297-312.
2. 14C]deoxyglucose method for measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem 1977;28:897-916.
3. Drevets WC, Raichle ME. Positron emission tomographic imaging studies of human emotional disorders. Cambridge, Massachusetts: MIT Press, 1995.
4. Alavi A, Hirsch LJ. Studies of central nervous system disorders with single photon emission computed tomography and positron emission tomography: evolution over the past 2 decades. Semin Nucl Med 1991;21:58-81.
5. Jezzard P, Haxby J, Sadato N, Rueckert L, Mattay V. Functional magnetic resonance imaging of the brain. Ann Intern Med 1995;122:296-303.
6. Belliveau JW, Kennedy DN Jr, McKinstry RC, Buchbinder BR, Weisskoff RM, Cohen MS, et al. Functional mapping of the human visual cortex by magnetic resonance imaging. Science 1991;254:716-9.
7. Moonen CTW. Imaging of human brain activation with functional MRI. Biol Psychiatry 1995;37:141-3.
8. Devous MD Sr. Imaging brain function by single-photon emission computer tomography. In: Andreasen NC, editor. Brain imaging: applications in psychiatry. Washington, DC: American Psychiatric Press, 1989:147-234.
9. Reba RC. PET and SPECT: opportunities and challenges for psychiatry. J Clin Psychiatry 1993;54(suppl):26-32.
10. Prohovnik IP. SPECT imaging of cerebral physiology. In: Oldham JM, Riba MB, Tasman A, editors. Review of psychiatry. Washington, DC: American Psychiatric Press, 1993:421-60.
11. Van Heertum RL, Tikofsky RS, editors. Cerebral SPECT imaging. 2nd ed. New York: Raven, 1995.
12. Moretti JL, Caglar M, Weinmann P. Cerebral perfusion imaging tracers for SPECT: which one to choose? J Nucl Med 1995;36:359-63.
13. Purl BK, Lewis SW. Single photon emission computerized tomography (SPECT) in neuropsychiatry: a review. Behav Neurol 1992;5:139-47.
14. Trzepacz PT, Hertweck M, Starratt C, Zimmerman L, Adatepe MH. The relationship of SPECT scans to behavioral dysfunction in neuropsychiatric patients. Psychosomatics 1992;33:62-71.
15. Jagust WJ. Functional imaging in dementia: an overview. J Clin Psychiatry 1994;55(11 suppl):5-11.
16. Mayberg HS. Clinical correlates of PET and SPECT identified defects in dementia. J Clin Psychiatry 1994;55(11 suppl):12-21.
17. Sloan EP, Fenton GW, Kennedy NSJ, MacLennan JM. Neurophysiology and SPECT cerebral blood flow patterns in dementia. Electroencephalogr Clin Neurophysiol 1994;91:163-70.
18. Holman BL, Johnson KA, Gerada B, Carvalho PA, Satlin A. The scintigraphic appearance of Alzheimer's disease: a prospective study using technetium 99m-HMPAO SPECT. J Nucl Med 1992;33:181-5.
19. Jobst KA, Hindley NJ, King EK, Smith AD. The diagnosis of Alzheimer's disease: a question of image? J Clin Psychiatry 1994;55(11 suppl):22-31.
20. Jagust WJ, Reed BR, Martin EM. Cognitive function and regional cerebral blood flow in Parkinson's disease. Brain 1992;115:521-37.
21. 99mTc-d,l-HMPAO and SPECT of the brain in normal aging. J Cereb Blood Flow Metab 1991; 11:508-21.
22. 99mHMPAO SPECT and temporal lobe oriented x-ray CT scans [Abstract]. J Nucl Med 1994;35:20.
23. Besson JAO, Crawford JR, Parker DM, Ebmeier KP, Best PV, Gemmell HG, et al. Multimodal imaging in Alzheimer's disease: the relationship between MRI, SPECT, cognitive and pathological changes. Br J Psychiatry 1990;157:216-20.
24. Eberling JL, Jagust WJ, Reed BR. Single photon emission computed tomography studies of regional cerebral blood flow in multi-infarct dementia. J Neuroimaging 1992;2:79-85.
25. Renshaw PF, Cohen BM. Functional brain imaging in the elderly. J Nucl Med 1993;34:1101-2.
26. Curran SM, Murray CM, Van Beck M, Dougall N, O'Carroll RE, Austin MP, et al. A single photon emission computerized tomography study of regional brain function in elderly patients with major depression and with Alzheimer-type dementia. Br J Psychiatry 1993;163:155-65.
27. Sackeim HA, Prohovnik I, Moeller JR, Mayeux R, Stern Y, Devenand DP. Regional cerebral blood flow in mood disorders. II. Comparison of major depression and Alzheimer's disease. J Nucl Med 1993;34:1090-101.
28. Dolan RJ, Bench CJ, Brown RG, Scott LC, Friston KJ, Frackowiak RSJ. Regional cerebral blood flow abnormalities in depressed patients with cognitive impairment. J Neurol Neurosurg Psychiatry 1992;55:768-73.
29. Devous MD Sr, Leroy RF, Homan RW. Single photon emission computed tomography in epilepsy. Semin Nucl Med 1990;20: 325-11.
30. Fayad PB, Brass LM. Single photon emission computed tomography in cerebrovascular disease. Stroke 1991;22:950-4.
31. Rubens AB, Coslett HB. Cerebrovascular disease. In: Van Heertum RL, Rikofsky RS, editors. Cerebral SPECT imaging. 2nd ed. New York: Raven, 1995:52-110.
32. 99mTc-hexamethylpropyleneamine oxime single photon emission CT in poststroke depression. Am J Psychiatry 1990;147:242-4.
33. Biersack HJ, Grunwald F, Knopp J. Single photon emission computed tomography imaging of brain tumors. Semin Nucl Med 1990;4:342-52.
34. Holman BL, Garada B, Johnson KA. A comparison of brain perfusion SPECT in cocaine abuse and AIDS dementia complex. J Nucl Med 1992;33:1312-5.
35. Devous MD Sr, Gullion CM, Grannemann BD, Trivedi MH, Rush AJ. Regional cerebral blood flow alterations in unipolar depression. Psychiatry Res 1993;50:233-56.
36. Sackeim HA, Prohovnik I. Brain imaging studies of depressive disorders. In: Mann JJ, Kupfer DJ, editors. Biology of depressive disorders; part A: a systems perspective. New York: Plenum, 1993:205-58.
37. Bolwig TG. Regional cerebral blood flow in affective disorder. Acta Psychiatr Scand 1993;371(suppl):48-53.
38. Schwartz JA, Speed NM. SPECT research in affective disorders. In: Racagni G, Brunello N, Fukuda T, editors. Biological psychiatry, vol 1. London: Elsevier, 1991:87-90.
39. George MS, Ketter TA, Post RM. SPECT and PET imaging in mood disorders. J Clin Psychiatry 1993;54(11 suppl):6-13.
40. 99mTc-exametazime in major depression and the pattern of brain activity underlying the psychotic/neurotic continuum. J Affect Disord 1992;26:31-43.
41. 99mTc-HMPAO single photon emission tomography method. Eur J Nucl Med 1992; 19:1038-43.
42. Ebert D, Feistel H, Barocka A. Effects of sleep deprivation on the limbic system and the frontal lobes in affective disorders: a study with Tc-99m HMPAO SPECT. Psychiatry Res 1991; 40:247-51.
43. Bench CJ, Friston KJ, Brown RG, Scott L, Frackowiak RSJ, Dolan RJ. The anatomy of melancholia: abnormalities of regional cerebral blood flow in major depression. Psychol Med 1992;22:607-15.
44. Thomas P, Vaiva G, Samaille E, Maron M, Alaix C, Steinling M, et al. Cerebral blood flow in major depression and dysthymia. J Affect Disord 1993;29:235-42.
45. Sackeim HA, Prohovnik I, Moeller JR, Brown JR, Apter S, Prudic J, et al. Regional cerebral blood flow in mood disorders; I: Comparisons of major depressives and normal controls at rest. Arch Gen Psychiatry 1990;47:60-70.
46. Lesser IM, Mena I, Boone KB, Miller BL, Mehringer CM, Wohl M. Reduction of cerebral blood flow in older depressed patients. Arch Gen Psychiatry 1994;51:677-86.
47. Mayberg HS, Lewis PJ, Regenold W, Wagner HN Jr. Paralimbic hypoperfusion in unipolar depression. J Nucl Med 1994; 35:929-34.
48. Amsterdam JD, Mozley DP. Temporal lobe asymmetry with iofetamine (IMP) SPECT imaging in patients with major depression. J Affect Disord 1992;24:43-53.
49. Cummings JL. The neuroanatomy of depression. J Clin Psychiatry 1993;54(11 suppl):14-20.
50. Baxter LR Jr, Schwartz JM, Phelps ME, Mazziotta JC, Guze BH, Selin CE, et al. Reduction of prefrontal cortex glucose metabolism common to three types of depression. Arch Gen Psychiatry 1989;46:243-50.
51. Martinot JL, Hardy P, Feline A. Huret JD, Mazoyer B, Attar-Levy D, et al. Left prefrontal glucose hypometabolism in the depressed state: a confirmation. Am J Psychiatry 1990;147: 1313-7.
52. Kumar A, Newberg A, Alavi A, Aberlin J, Smith R, Reivish M. Regional cerebral glucose metabolism in late-life depression and Alzheimer's disease: a preliminary positron emission tomography study. Proc Natl Acad Sci U S A 1993;90: 7019-23.
53. Martin AJ, Friston KJ, Colebatch JG, Frackowiak RSJ. Decreases in regional cerebral blood flow with normal aging. J Cereb Blood Flow Metab 1991;11:684-9.
54. Maes M, Dierckx R, Meltzer HY, Ingels M, Schotte C, Vandewoude M, et al. Regional cerebral blood flow in unipolar depression measured with Tc-99m-HMPAO single photon emission computed tomography: negative findings. Psychiatry Res 1993;50:77-88.
55. Reischies FM, Hedde JP, Drochner R. Clinical correlates of cerebral blood flow in depression. Psychiatry Res 1989;29: 323-6.
56. Silfverskiöld P, Risberg J. Regional cerebral blood flow in depression and mania. Arch Gen Psychiatry 1989;46:253-9.
57. Schwartz RB, Komaroff AL, Garada BM, Gleit M, Doolittle TH, Bates DW, et al. SPECT imaging of the brain: comparison of findings in patients with chronic fatigue syndrome, AIDS dementia complex and major unipolar depression. AJR Am J Roentgenol 1994;162:943-51.
58. 99mTc-hexamethylpropyleneamine oxime SPECT in elderly depressed patients. Psychiatry Res [In press].
59. Dolan RJ, Bench CJ, Liddle PF, Friston KJ, Frith CD, Grasby PM, et al. Dorsolateral prefrontal cortex dysfunction in the major psychoses; symptom or disease specificity? J Neurol Neurosurg Psychiatry 1993;56:1290-4.
60. D'haenen H, Bossuyt A, Mertens J, Bossuyt-Piron C, Gijsemans M, Kaufman L. SPECT imaging of serotonin 2 receptors in depression. Psychiatry Res 1992;45:227-37.
61. Rubin E, Sackeim HA, Nobler MS, Moeller JR. Brain imaging studies of antidepressant treatments. Psychiatr Ann 1994;24: 653-8.
62. Drevets WC, Videen TO, Price JL, Preskorn SH, Carmichael ST, Raichle ME. A functional anatomical study of unipolar depression. J Neurosci 1992;12:3628-41.
63. 99mTc-exametazime with single photon emission tomography in major depression before and after treatment. J Affect Disord 1993;29:243-53.
64. Kumar A, Mozley D, Dunham C, Velchik M, Reilley J, Gottlieb G, et al. Semiquantitative I-123 IMP SPECT studies in late onset depression before and after treatment. Int J Geriatr Psychiatry 1991;6:775-7.
65. Ebert D, Feistel H, Barocka A, Kaschka W. Increased limbic flow and total sleep deprivation in major depression with melancholia. Psychiatry Res 1994;55:101-9.
66. Murphy DG, Murphy DM, Abbas M, Palzidou E, Binnie C, Arendt J, et al. Seasonal affective disorder: response to light as measured by electroencephalogram, melatonin suppression, and cerebral blood flow. Br J Psychiatry 1993;163: 327-31.
67. Sachs G, Vasile RG, Anderson JL, Lafer B, Matthews E, Hill T. Changes in regional cerebral blood flow after light treatment for seasonal affective disorder: responders versus non-responders. Presented at the Seventh Annual Meeting on Light Treatment and Biological Rhythms, Frankfurt, Germany, June 1995.
68. Nobler MS, Sackeim HA, Prohovnik I, Moeller JR, Mukherjee S, Schnur DB. Regional cerebral blood flow in mood disorders, III: Treatment and clinical response. Arch Gen Psychiatry 1994;51:884-97.
69. Bajc M, Medved V, Basic M, Topuzovic N, Babic D, Ivancevic D. Acute effect of electroconvulsive therapy on brain perfusion assessed by Tc99m-hexamethylpropyleneamineoxim and single photon emission computed tomography. Acta Psychiatr Scand 1989;80:421-6.
70. Lere B, Krausz Y, Bonne O, Shapira B, Karger H, Chisin R. ECT, antidepressant response and cerebral blood flow in patients with major depression [Abstract]. Neuropsychopharmacology 1994;10(suppl 3,1):567S.
71. Vasile RG, Hill TC, Bradley FM, Bloomingdale KB, Schildkraut JJ. Increase in left frontal cerebral blood flow following electroconvulsive treatment for depression [Abstract]. Neuropsychopharmacology 1994;10(suppl 3,2):247S.
72. 99mTc-exametazime into brain in major depression shown with single photon emission tomography. J Affect Disord 1994;30:27-34.
73. 2 receptor blockade in depression before and after sleep deprivation - preliminary results. Biol Psychiatry 1994;35:880-5.
74. 2 receptor imaging with SPECT: studies in different neuropsychiatric disorders. J Cereb Blood Flow Metab 1991;11:220-8.
75. Innis RB. Neuroreceptor imaging with SPECT. J Clin Psychiatry 1992;53(11 suppl):29-34.
76. D'haenen HA, Bossuyt A. Dopamine D2 receptors in depression measured with single photon emission computed tomography. Biol Psychiatry 1994;35:128-32.
77. Innis RB, Al-Tikriti MS, Zoghbi SS, Baldwin RM, Sybirska EH, Lamelle MA, et al. SPECT imaging of the benzodiazepine receptor: feasibility of in vivo potency measurements from stepwise displacement curves. J Nucl Med 1991;32:1754-61.
78. 99mTc-HMPAO single photon emission tomography in late life depression: a pilot study of regional cerebral blood flow at rest and during a verbal fluency task. J Affect Disord 1993;28:233-40.
79. Rezai K, Andreasen NC, Alliger R, Cohen G, Swayze V, O'Leary DS. The neuropsychology of the prefrontal cortex. Arch Neurol 1993;50:636-42.
80. Kotrla K, Chacko RC, Harper RG, Jhingran S, Doody R. SPECT findings on psychosis in Alzheimer's disease. Am J Psychiatry 1995;152:1470-5.
81. Chan KH, Johnson KA, Becker JA, Satlin A, Mendelson J, Garada B, et al. A neural network classifier for cerebral perfusion imaging. J Nucl Med 1994;35:771-4.
82. Johnson KA, Kijewski MF, Becker JA, Satlin A, Holman BL. Quantitative brain SPECT in Alzheimer's disease and normal aging. J Nucl Med 1993;34:2044-8.
83. De Christofaro MT, Sessarego A, Pupi A, Biondi F, Faravelli C. Brain perfusion abnormalities in drug-naive, lactate-sensitive panic patients: a SPECT study. Biol Psychiatry 1993;33:505-12.
84. 99mTc-exametazime shown by single photon emission computerized tomography in obsessive-compulsive disorder compared with major depression and normal controls. Acta Psychiatr Scand 1994;90:298-303.
85. George MS. The contributions of positron emission tomography and single-photon emission computed tomography toward a psychopharmacological neuroanatomy of obsessive-compulsive disorder. In: Hindmarch I, Stonier D, editors. Human psychopharmacology: measures and methods, vol 4. Chichester, England: John Wiley, 1993:99-122.
86. Rubin E, Sackeim H, Prohovnik I, Moeller JR, Schnur DB, Mukherjee S. Regional cerebral blood flow in mood disorders; IV: Comparison of mania and depression. Psychiatry Res 1995;61:1-10.
87. Andreasen NC, Cohen G, Harris G, Cizadlo T, Parkkinen J, Rezai K, et al. Image processing for the study of brain structure and function: problems and programs. J Neuropsychiatry Clin Neurosci 1992;4:125-33.
88. 201thallium SPECT images of the brain. J Nucl Med 1991;32:1478-84.
89. Drevets WC, Raichle ME. Neuroanatomical circuits in depression: implications for treatment mechanisms. Psychopharmacol Bull 1992;28:261-74.
90. Kanaya T, Yonekawa M. Regional cerebral blood flow in depression. Jpn J Psychiatr Neurol 1990;44:571-6.
91. Delvenne F, Delecluse F, Hubain P, Schoutens A, De Maertelaer V, Mendlewicz J. Regional cerebral blood flow in patients with affective disorders. Br J Psychiatry 1990;157:359-65.